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Items: 18


Effects of Absence of Constitutive Androstane Receptor (CAR) on Bile Acid Homeostasis in Male and Female Mice.

Lickteig AJ, Zhang Y, Klaassen CD, Csanaky IL.

Toxicol Sci. 2019 Jun 21. pii: kfz143. doi: 10.1093/toxsci/kfz143. [Epub ahead of print]


Aryl hydrocarbon receptor (AhR) mediated short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on bile acid homeostasis in mice.

Csanaky IL, Lickteig AJ, Klaassen CD.

Toxicol Appl Pharmacol. 2018 Mar 15;343:48-61. doi: 10.1016/j.taap.2018.02.005. Epub 2018 Feb 13.


Activation of PPARĪ± decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion.

Zhang Y, Lickteig AJ, Csanaky IL, Klaassen CD.

Toxicol Appl Pharmacol. 2018 Jan 1;338:112-123. doi: 10.1016/j.taap.2017.11.014. Epub 2017 Nov 22.


Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARĪ±-Dependent Manner.

Zhang Y, Lickteig AJ, Csanaky IL, Klaassen CD.

Toxicol Sci. 2017 Dec 1;160(2):351-360. doi: 10.1093/toxsci/kfx191.


Urinary Concentrations of Topically Administered Pain Medications.

Glinn MA, Lickteig AJ, Weber L, Recer S, Salske M, Harvey A, Rappold B, Stensland J, Bell P.

J Anal Toxicol. 2017 Mar 1;41(2):127-133. doi: 10.1093/jat/bkw110.


Activation of Constitutive Androstane Receptor (CAR) in Mice Results in Maintained Biliary Excretion of Bile Acids Despite a Marked Decrease of Bile Acids in Liver.

Lickteig AJ, Csanaky IL, Pratt-Hyatt M, Klaassen CD.

Toxicol Sci. 2016 Jun;151(2):403-18. doi: 10.1093/toxsci/kfw054. Epub 2016 Mar 16.


Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene.

Canet MJ, Merrell MD, Harder BG, Maher JM, Wu T, Lickteig AJ, Jackson JP, Zhang DD, Yamamoto M, Cherrington NJ.

Drug Metab Dispos. 2015 Jan;43(1):93-9. doi: 10.1124/dmd.114.060103. Epub 2014 Oct 27.


Synergistic interaction between genetics and disease on pravastatin disposition.

Clarke JD, Hardwick RN, Lake AD, Lickteig AJ, Goedken MJ, Klaassen CD, Cherrington NJ.

J Hepatol. 2014 Jul;61(1):139-47. doi: 10.1016/j.jhep.2014.02.021. Epub 2014 Mar 5.


Tissue distribution, ontogeny, and chemical induction of aldo-keto reductases in mice.

Pratt-Hyatt M, Lickteig AJ, Klaassen CD.

Drug Metab Dispos. 2013 Aug;41(8):1480-7. doi: 10.1124/dmd.113.051904. Epub 2013 May 9.


Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease.

Fisher CD, Lickteig AJ, Augustine LM, Ranger-Moore J, Jackson JP, Ferguson SS, Cherrington NJ.

Drug Metab Dispos. 2009 Oct;37(10):2087-94. doi: 10.1124/dmd.109.027466. Epub 2009 Aug 3.


Expression and characterization of functional dog flavin-containing monooxygenase 3.

Lickteig AJ, Riley R, Melton RJ, Reitz BA, Fischer HD, Stevens JC.

Drug Metab Dispos. 2009 Oct;37(10):1987-90. doi: 10.1124/dmd.109.027714. Epub 2009 Jul 27.


Experimental non-alcoholic fatty liver disease results in decreased hepatic uptake transporter expression and function in rats.

Fisher CD, Lickteig AJ, Augustine LM, Oude Elferink RP, Besselsen DG, Erickson RP, Cherrington NJ.

Eur J Pharmacol. 2009 Jun 24;613(1-3):119-27. doi: 10.1016/j.ejphar.2009.04.002. Epub 2009 Apr 7.


Tissue distribution, ontogeny and induction of the transporters Multidrug and toxin extrusion (MATE) 1 and MATE2 mRNA expression levels in mice.

Lickteig AJ, Cheng X, Augustine LM, Klaassen CD, Cherrington NJ.

Life Sci. 2008 Jul 4;83(1-2):59-64. doi: 10.1016/j.lfs.2008.05.004. Epub 2008 May 18.


Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.

Fisher CD, Jackson JP, Lickteig AJ, Augustine LM, Cherrington NJ.

Arch Toxicol. 2008 Dec;82(12):959-64. doi: 10.1007/s00204-008-0312-z. Epub 2008 May 17.


Gender divergent expression of Nqo1 in Sprague Dawley and August Copenhagen x Irish rats.

Augustine LM, Fisher CD, Lickteig AJ, Aleksunes LM, Slitt AL, Cherrington NJ.

J Biochem Mol Toxicol. 2008 Mar-Apr;22(2):93-100. doi: 10.1002/jbt.20224.


Genes of the antioxidant response undergo upregulation in a rodent model of nonalcoholic steatohepatitis.

Lickteig AJ, Fisher CD, Augustine LM, Cherrington NJ.

J Biochem Mol Toxicol. 2007;21(4):216-20.


Efflux transporter expression and acetaminophen metabolite excretion are altered in rodent models of nonalcoholic fatty liver disease.

Lickteig AJ, Fisher CD, Augustine LM, Aleksunes LM, Besselsen DG, Slitt AL, Manautou JE, Cherrington NJ.

Drug Metab Dispos. 2007 Oct;35(10):1970-8. Epub 2007 Jul 19.


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