Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 309

1.

CD8+-T Cells With Specificity for a Model Antigen in Cardiomyocytes Can Become Activated After Transverse Aortic Constriction but Do Not Accelerate Progression to Heart Failure.

Gröschel C, Sasse A, Monecke S, Röhrborn C, Elsner L, Didié M, Reupke V, Bunt G, Lichtman AH, Toischer K, Zimmermann WH, Hasenfuß G, Dressel R.

Front Immunol. 2018 Nov 15;9:2665. doi: 10.3389/fimmu.2018.02665. eCollection 2018.

2.

Neuronal nicotinic acetylcholine receptors mediate ∆9 -THC dependence: Mouse and human studies.

Donvito G, Muldoon PP, Jackson KJ, Ahmad U, Zaveri NT, McIntosh JM, Chen X, Lichtman AH, Damaj MI.

Addict Biol. 2018 Oct 31. doi: 10.1111/adb.12691. [Epub ahead of print]

PMID:
30378732
3.

Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS.

Hermes DJ, Xu C, Poklis JL, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S.

Neuropharmacology. 2018 Oct;141:55-65. doi: 10.1016/j.neuropharm.2018.08.013. Epub 2018 Aug 13.

4.

Differential Tolerance to FTY720-Induced Antinociception in Acute Thermal and Nerve Injury Mouse Pain Models: Role of Sphingosine-1-Phosphate Receptor Adaptation.

Sim-Selley LJ, Wilkerson JL, Burston JJ, Hauser KF, McLane V, Welch SP, Lichtman AH, Selley DE.

J Pharmacol Exp Ther. 2018 Sep;366(3):509-518. doi: 10.1124/jpet.118.248260. Epub 2018 Jun 26.

PMID:
29945931
5.

Vasoactive Intestinal Peptide Ameliorates Acute Myocarditis and Atherosclerosis by Regulating Inflammatory and Autoimmune Responses.

Benitez R, Delgado-Maroto V, Caro M, Forte-Lago I, Duran-Prado M, O'Valle F, Lichtman AH, Gonzalez-Rey E, Delgado M.

J Immunol. 2018 Jun 1;200(11):3697-3710. doi: 10.4049/jimmunol.1800122. Epub 2018 Apr 18.

PMID:
29669783
6.

IL-23R Deficiency Does Not Impact Atherosclerotic Plaque Development in Mice.

Engelbertsen D, Depuydt MAC, Verwilligen RAF, Rattik S, Levinsohn E, Edsfeldt A, Kuperwaser F, Jarolim P, Lichtman AH.

J Am Heart Assoc. 2018 Apr 4;7(8). pii: e008257. doi: 10.1161/JAHA.117.008257.

7.

N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice.

Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, Lichtman AH, Damaj MI, Di Marzo V, Mechoulam R.

Neuropharmacology. 2018 Mar 19. pii: S0028-3908(18)30131-X. doi: 10.1016/j.neuropharm.2018.03.020. [Epub ahead of print]

PMID:
29567093
8.

Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy.

Curry ZA, Wilkerson JL, Bagdas D, Kyte SL, Patel N, Donvito G, Mustafa MA, Poklis JL, Niphakis MJ, Hsu KL, Cravatt BF, Gewirtz DA, Damaj MI, Lichtman AH.

J Pharmacol Exp Ther. 2018 Jul;366(1):169-183. doi: 10.1124/jpet.117.245704. Epub 2018 Mar 14.

PMID:
29540562
9.

Evaluation of different drug classes on transient sciatic nerve injury-depressed marble burying in mice.

Wilkerson JL, Curry ZA, Kinlow PD, Mason BL, Hsu KL, van der Stelt M, Cravatt BF, Lichtman AH.

Pain. 2018 Jun;159(6):1155-1165. doi: 10.1097/j.pain.0000000000001199.

PMID:
29528965
10.

Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity.

Dopart R, Lu D, Lichtman AH, Kendall DA.

Drug Metab Rev. 2018 Feb;50(1):3-13. doi: 10.1080/03602532.2018.1428342. Epub 2018 Jan 21. Review.

PMID:
29355030
11.

T helper cells with specificity for an antigen in cardiomyocytes promote pressure overload-induced progression from hypertrophy to heart failure.

Gröschel C, Sasse A, Röhrborn C, Monecke S, Didié M, Elsner L, Kruse V, Bunt G, Lichtman AH, Toischer K, Zimmermann WH, Hasenfuß G, Dressel R.

Sci Rep. 2017 Nov 22;7(1):15998. doi: 10.1038/s41598-017-16147-1.

12.

Monocyte-Macrophages and T Cells in Atherosclerosis.

Tabas I, Lichtman AH.

Immunity. 2017 Oct 17;47(4):621-634. doi: 10.1016/j.immuni.2017.09.008. Review.

13.

Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN.

Kyte SL, Toma W, Bagdas D, Meade JA, Schurman LD, Lichtman AH, Chen ZJ, Del Fabbro E, Fang X, Bigbee JW, Damaj MI, Gewirtz DA.

J Pharmacol Exp Ther. 2018 Jan;364(1):110-119. doi: 10.1124/jpet.117.243972. Epub 2017 Oct 17.

PMID:
29042416
14.

Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model.

Wilkerson JL, Donvito G, Grim TW, Abdullah RA, Ogasawara D, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2017 Dec;363(3):394-401. doi: 10.1124/jpet.117.243808. Epub 2017 Oct 2.

15.

Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain.

Lichtman AH, Lux EA, McQuade R, Rossetti S, Sanchez R, Sun W, Wright S, Kornyeyeva E, Fallon MT.

J Pain Symptom Manage. 2018 Feb;55(2):179-188.e1. doi: 10.1016/j.jpainsymman.2017.09.001. Epub 2017 Sep 18.

PMID:
28923526
16.

Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo.

Shin M, Snyder HW, Donvito G, Schurman LD, Fox TE, Lichtman AH, Kester M, Hsu KL.

Mol Pharm. 2018 Mar 5;15(3):721-728. doi: 10.1021/acs.molpharmaceut.7b00657. Epub 2017 Sep 13.

PMID:
28901776
17.

Unraveling Vascular Inflammation: From Immunology to Imaging.

Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, Mehta NN.

J Am Coll Cardiol. 2017 Sep 12;70(11):1403-1412. doi: 10.1016/j.jacc.2017.07.750. Review.

18.

A role for T helper cells in anti-CTLA-4 therapy.

Lichtman AH.

Sci Immunol. 2017 Sep 1;2(15). pii: eaao6871. doi: 10.1126/sciimmunol.aao6871.

PMID:
28864497
19.

The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain.

Donvito G, Nass SR, Wilkerson JL, Curry ZA, Schurman LD, Kinsey SG, Lichtman AH.

Neuropsychopharmacology. 2018 Jan;43(1):52-79. doi: 10.1038/npp.2017.204. Epub 2017 Aug 31. Review.

PMID:
28857069
20.

Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies.

Fallon MT, Albert Lux E, McQuade R, Rossetti S, Sanchez R, Sun W, Wright S, Lichtman AH, Kornyeyeva E.

Br J Pain. 2017 Aug;11(3):119-133. doi: 10.1177/2049463717710042. Epub 2017 May 17.

21.

Help not wanted in the joint.

Lichtman AH.

Sci Immunol. 2017 Mar 3;2(9). pii: eaan0289. doi: 10.1126/sciimmunol.aan0289.

PMID:
28783699
22.

Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein.

Xu C, Hermes DJ, Nwanguma B, Jacobs IR, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska B, Fitting S.

Mol Cell Neurosci. 2017 Sep;83:92-102. doi: 10.1016/j.mcn.2017.07.003. Epub 2017 Jul 19.

23.

Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice.

Owens RA, Mustafa MA, Ignatowska-Jankowska BM, Damaj MI, Beardsley PM, Wiley JL, Niphakis MJ, Cravatt BF, Lichtman AH.

Neuropharmacology. 2017 Oct;125:80-86. doi: 10.1016/j.neuropharm.2017.06.032. Epub 2017 Jun 30.

24.

The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice.

Donvito G, Bagdas D, Toma W, Rahimpour E, Jackson A, Meade JA, AlSharari S, Kulkarni AR, Ivy Carroll F, Lichtman AH, Papke RL, Thakur GA, Imad Damaj M.

Exp Neurol. 2017 Sep;295:194-201. doi: 10.1016/j.expneurol.2017.06.014. Epub 2017 Jun 9.

25.

Investigation of left and right lateral fluid percussion injury in C57BL6/J mice: In vivo functional consequences.

Schurman LD, Smith TL, Morales AJ, Lee NN, Reeves TM, Phillips LL, Lichtman AH.

Neurosci Lett. 2017 Jul 13;653:31-38. doi: 10.1016/j.neulet.2017.05.032. Epub 2017 May 17.

26.

Innate lymphoid cells in atherosclerosis.

Engelbertsen D, Lichtman AH.

Eur J Pharmacol. 2017 Dec 5;816:32-36. doi: 10.1016/j.ejphar.2017.04.030. Epub 2017 Apr 25. Review.

PMID:
28449862
27.

Apparent CB1 Receptor Rimonabant Affinity Estimates: Combination with THC and Synthetic Cannabinoids in the Mouse In Vivo Triad Model.

Grim TW, Morales AJ, Thomas BF, Wiley JL, Endres GW, Negus SS, Lichtman AH.

J Pharmacol Exp Ther. 2017 Jul;362(1):210-218. doi: 10.1124/jpet.117.240192. Epub 2017 Apr 25.

28.

Cortistatin reduces atherosclerosis in hyperlipidemic ApoE-deficient mice and the formation of foam cells.

Delgado-Maroto V, Benitez R, Forte-Lago I, Morell M, Maganto-Garcia E, Souza-Moreira L, O'Valle F, Duran-Prado M, Lichtman AH, Gonzalez-Rey E, Delgado M.

Sci Rep. 2017 Apr 13;7:46444. doi: 10.1038/srep46444.

29.

In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence.

Jackson A, Bagdas D, Muldoon PP, Lichtman AH, Carroll FI, Greenwald M, Miles MF, Damaj MI.

Neuropharmacology. 2017 May 15;118:38-45. doi: 10.1016/j.neuropharm.2017.03.005. Epub 2017 Mar 7.

30.

Endocannabinoids: A Promising Impact for Traumatic Brain Injury.

Schurman LD, Lichtman AH.

Front Pharmacol. 2017 Feb 17;8:69. doi: 10.3389/fphar.2017.00069. eCollection 2017. Review.

31.

Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse.

Toma W, Kyte SL, Bagdas D, Alkhlaif Y, Alsharari SD, Lichtman AH, Chen ZJ, Del Fabbro E, Bigbee JW, Gewirtz DA, Damaj MI.

Neuropharmacology. 2017 May 1;117:305-315. doi: 10.1016/j.neuropharm.2017.02.020. Epub 2017 Feb 22.

32.

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.

Soethoudt M, Grether U, Fingerle J, Grim TW, Fezza F, de Petrocellis L, Ullmer C, Rothenhäusler B, Perret C, van Gils N, Finlay D, MacDonald C, Chicca A, Gens MD, Stuart J, de Vries H, Mastrangelo N, Xia L, Alachouzos G, Baggelaar MP, Martella A, Mock ED, Deng H, Heitman LH, Connor M, Di Marzo V, Gertsch J, Lichtman AH, Maccarrone M, Pacher P, Glass M, van der Stelt M.

Nat Commun. 2017 Jan 3;8:13958. doi: 10.1038/ncomms13958.

33.

Defects in CD4+ T cell LFA-1 integrin-dependent adhesion and proliferation protect Cd47-/- mice from EAE.

Azcutia V, Bassil R, Herter JM, Engelbertsen D, Newton G, Autio A, Mayadas T, Lichtman AH, Khoury SJ, Parkos CA, Elyaman W, Luscinskas FW.

J Leukoc Biol. 2017 Feb;101(2):493-505. doi: 10.1189/jlb.3A1215-546RR. Epub 2016 Dec 13.

34.

The neuropeptide cortistatin attenuates experimental autoimmune myocarditis via inhibition of cardiomyogenic T cell-driven inflammatory responses.

Delgado-Maroto V, Falo CP, Forte-Lago I, Adan N, Morell M, Maganto-Garcia E, Robledo G, O'Valle F, Lichtman AH, Gonzalez-Rey E, Delgado M.

Br J Pharmacol. 2017 Feb;174(3):267-280. doi: 10.1111/bph.13682. Epub 2017 Jan 8.

35.

The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice.

Wilkerson JL, Ghosh S, Mustafa M, Abdullah RA, Niphakis MJ, Cabrera R, Maldonado RL, Cravatt BF, Lichtman AH.

Neuropharmacology. 2017 Mar 1;114:156-167. doi: 10.1016/j.neuropharm.2016.11.015. Epub 2016 Nov 25.

36.

Dendritic Cell KLF2 Expression Regulates T Cell Activation and Proatherogenic Immune Responses.

Alberts-Grill N, Engelbertsen D, Bu D, Foks A, Grabie N, Herter JM, Kuperwaser F, Chen T, Destefano G, Jarolim P, Lichtman AH.

J Immunol. 2016 Dec 15;197(12):4651-4662. Epub 2016 Nov 11.

37.

Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

Johnson DB, Balko JM, Compton ML, Chalkias S, Gorham J, Xu Y, Hicks M, Puzanov I, Alexander MR, Bloomer TL, Becker JR, Slosky DA, Phillips EJ, Pilkinton MA, Craig-Owens L, Kola N, Plautz G, Reshef DS, Deutsch JS, Deering RP, Olenchock BA, Lichtman AH, Roden DM, Seidman CE, Koralnik IJ, Seidman JG, Hoffman RD, Taube JM, Diaz LA Jr, Anders RA, Sosman JA, Moslehi JJ.

N Engl J Med. 2016 Nov 3;375(18):1749-1755.

38.

Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice.

Donvito G, Wilkerson JL, Damaj MI, Lichtman AH.

J Pharmacol Exp Ther. 2016 Nov;359(2):310-318. Epub 2016 Sep 8.

39.

Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro Assays.

Grim TW, Morales AJ, Gonek MM, Wiley JL, Thomas BF, Endres GW, Sim-Selley LJ, Selley DE, Negus SS, Lichtman AH.

J Pharmacol Exp Ther. 2016 Nov;359(2):329-339. Epub 2016 Aug 17.

40.

Just add water: cannabinoid discrimination in a water T-maze with FAAH(-/-) and FAAH(+/+) mice.

Wiley JL, Lefever TW, Pulley NS, Marusich JA, Cravatt BF, Lichtman AH.

Behav Pharmacol. 2016 Aug;27(5):479-84. doi: 10.1097/FBP.0000000000000228.

41.

Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice.

Owens RA, Ignatowska-Jankowska B, Mustafa M, Beardsley PM, Wiley JL, Jali A, Selley DE, Niphakis MJ, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2016 Aug;358(2):306-14. doi: 10.1124/jpet.115.229492. Epub 2016 Jun 15.

42.

Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids.

Wiley JL, Owens RA, Lichtman AH.

Curr Top Behav Neurosci. 2018;39:153-173. doi: 10.1007/7854_2016_24.

PMID:
27278640
43.

The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain.

Bagdas D, Wilkerson JL, Kulkarni A, Toma W, AlSharari S, Gul Z, Lichtman AH, Papke RL, Thakur GA, Damaj MI.

Br J Pharmacol. 2016 Aug;173(16):2506-20. doi: 10.1111/bph.13528. Epub 2016 Jul 18.

44.

Pharmacological characterization of repeated administration of the first generation abused synthetic cannabinoid CP47,497.

Grim TW, Samano KL, Ignatowska-Jankowska B, Tao Q, Sim-Selly LJ, Selley DE, Wise LE, Poklis A, Lichtman AH.

J Basic Clin Physiol Pharmacol. 2016 May 1;27(3):217-28. doi: 10.1515/jbcpp-2015-0118.

45.

Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices.

Xu C, Hermes DJ, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S.

J Neuroimmune Pharmacol. 2016 Jun;11(2):316-31. doi: 10.1007/s11481-016-9664-y. Epub 2016 Mar 18.

46.

Diacylglycerol lipase β inhibition reverses nociceptive behaviour in mouse models of inflammatory and neuropathic pain.

Wilkerson JL, Ghosh S, Bagdas D, Mason BL, Crowe MS, Hsu KL, Wise LE, Kinsey SG, Damaj MI, Cravatt BF, Lichtman AH.

Br J Pharmacol. 2016 May;173(10):1678-92. doi: 10.1111/bph.13469. Epub 2016 Apr 8.

47.

Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation and β-arrestin 2 activity in the forebrain.

Hahn YK, Paris JJ, Lichtman AH, Hauser KF, Sim-Selley LJ, Selley DE, Knapp PE.

Neurobiol Dis. 2016 Aug;92(Pt B):124-36. doi: 10.1016/j.nbd.2016.01.014. Epub 2016 Feb 1.

48.

Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice.

Foks AC, Engelbertsen D, Kuperwaser F, Alberts-Grill N, Gonen A, Witztum JL, Lederer J, Jarolim P, DeKruyff RH, Freeman GJ, Lichtman AH.

Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):456-65. doi: 10.1161/ATVBAHA.115.306860. Epub 2016 Jan 28.

49.

The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model.

Wilkerson JL, Niphakis MJ, Grim TW, Mustafa MA, Abdullah RA, Poklis JL, Dewey WL, Akbarali H, Banks ML, Wise LE, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2016 Apr;357(1):145-56. doi: 10.1124/jpet.115.229971. Epub 2016 Jan 20.

50.

AKAP9 regulates activation-induced retention of T lymphocytes at sites of inflammation.

Herter JM, Grabie N, Cullere X, Azcutia V, Rosetti F, Bennett P, Herter-Sprie GS, Elyaman W, Luscinskas FW, Lichtman AH, Mayadas TN.

Nat Commun. 2015 Dec 18;6:10182. doi: 10.1038/ncomms10182.

Supplemental Content

Loading ...
Support Center