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Distinctive and common features of moderate aplastic anaemia.

Patel BJ, Barot SV, Kuzmanovic T, Kerr C, Przychodzen BP, Thota S, Lee S, Patel S, Radivoyevitch T, Lichtin A, Advani A, Kalaycio M, Sekeres MA, Carraway HE, Maciejewski JP.

Br J Haematol. 2020 Jan 31. doi: 10.1111/bjh.16460. [Epub ahead of print]


Large granular lymphocytic laeukemia after solid organ and haematopoietic stem cell transplantation.

Awada H, Mahfouz RZ, Durrani J, Kishtagari A, Jagadeesh D, Lichtin AE, Hill BT, Hamilton BK, Carraway HE, Nazha A, Majhail NS, Sobecks R, Visconte V, Kalaycio M, Sekeres MA, Maciejewski JP.

Br J Haematol. 2020 Jan 20. doi: 10.1111/bjh.16336. [Epub ahead of print]


Isolated CNS leukaemic relapse in acute myeloid leukaemia.

Essa A, Gbadamosi-Akindele M, Lichtin A.

BMJ Case Rep. 2019 Dec 17;12(12). pii: e233499. doi: 10.1136/bcr-2019-233499. No abstract available.


Extended experience with a non-cytotoxic DNMT1-targeting regimen of decitabine to treat myeloid malignancies.

Awada H, Mahfouz RZ, Kishtagari A, Kuzmanovic T, Durrani J, Kerr CM, Patel BJ, Visconte V, Radivoyevitch T, Lichtin A, Carraway HE, Maciejewski JP, Saunthararajah Y.

Br J Haematol. 2019 Nov 17. doi: 10.1111/bjh.16281. [Epub ahead of print]


Large granular lymphocytic leukemia coexists with myeloid clones and myelodysplastic syndrome.

Durrani J, Awada H, Kishtagari A, Visconte V, Kerr C, Adema V, Nagata Y, Kuzmanovic T, Hong S, Patel B, Nazha A, Lichtin A, Mukherjee S, Saunthararajah Y, Carraway H, Sekeres M, Maciejewski JP.

Leukemia. 2019 Oct 17. doi: 10.1038/s41375-019-0601-y. [Epub ahead of print] No abstract available.


An unusual cause of bruising.

Atieh T, Lichtin A.

Cleve Clin J Med. 2019 Aug;86(8):535-542. doi: 10.3949/ccjm.86a.18119. No abstract available.


Subclonal STAT3 mutations solidify clonal dominance.

Kerr CM, Clemente MJ, Chomczynski PW, Przychodzen B, Nagata Y, Adema V, Visconte V, Lichtin AE, Mustjoki S, Radivoyevitch T, Sekeres MA, Maciejewski JP.

Blood Adv. 2019 Mar 26;3(6):917-921. doi: 10.1182/bloodadvances.2018027862.


Laparoscopic splenectomy for immune thrombocytopenia (ITP): long-term outcomes of a modern cohort.

Tastaldi L, Krpata DM, Prabhu AS, Petro CC, Haskins IN, Perez AJ, Alkhatib H, Colturato I, Tu C, Lichtin A, Rosen MJ, Rosenblatt S.

Surg Endosc. 2019 Feb;33(2):475-485. doi: 10.1007/s00464-018-6321-y. Epub 2018 Jul 9.


Clinical features and treatment outcomes in large granular lymphocytic leukemia (LGLL).

Sanikommu SR, Clemente MJ, Chomczynski P, Afable MG 2nd, Jerez A, Thota S, Patel B, Hirsch C, Nazha A, Desamito J, Lichtin A, Pohlman B, Sekeres MA, Radivoyevitch T, Maciejewski JP.

Leuk Lymphoma. 2018 Feb;59(2):416-422. doi: 10.1080/10428194.2017.1339880. Epub 2017 Jun 20.


Erythrocytosis due to presumed polycythemia vera.

Patell R, Theil K, Lichtin A.

Cleve Clin J Med. 2016 Sep;83(9):648-53. doi: 10.3949/ccjm.83a.15154. Review. No abstract available.


Thrombotic thrombocytopenic purpura: The role of ADAMTS13.

Rogers HJ, Allen C, Lichtin AE.

Cleve Clin J Med. 2016 Aug;83(8):597-603. doi: 10.3949/ccjm.83a.15009. Review.


Ankle pain in a young woman with Gaucher disease.

Kattoor AJ, Bauer TW, Berkowitz M, Polster JM, Lichtin AE.

Cleve Clin J Med. 2015 Sep;82(9):607-13. doi: 10.3949/ccjm.82a.14108. No abstract available.


Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes.

Saunthararajah Y, Sekeres M, Advani A, Mahfouz R, Durkin L, Radivoyevitch T, Englehaupt R, Juersivich J, Cooper K, Husseinzadeh H, Przychodzen B, Rump M, Hobson S, Earl M, Sobecks R, Dean R, Reu F, Tiu R, Hamilton B, Copelan E, Lichtin A, Hsi E, Kalaycio M, Maciejewski J.

J Clin Invest. 2015 Mar 2;125(3):1043-55. doi: 10.1172/JCI78789. Epub 2015 Jan 26.


Cyclosporine dependent pure red cell aplasia: a case presentation.

Al-Issa K, Visconte V, Rogers HJ, Dembla V, Lichtin AE, Tiu RV.

Blood Cells Mol Dis. 2015 Mar;54(3):281-3. doi: 10.1016/j.bcmd.2014.11.013. Epub 2014 Nov 25. No abstract available.


Screening for SF3B1 mutations is a useful tool to differentiate between acquired clonal and non-clonal sideroblastic anemia.

Visconte V, Tabarroki A, Gerace CJ, Al-Issa K, Hsi ED, Rogers HJ, Sekeres MA, Silver BJ, Lichtin AE, Mukherjee S, Tiu RV.

Leuk Lymphoma. 2015 Jun;56(6):1888-90. doi: 10.3109/10428194.2014.976821. Epub 2014 Nov 14. No abstract available.


Ruxolitinib leads to improvement of pulmonary hypertension in patients with myelofibrosis.

Tabarroki A, Lindner DJ, Visconte V, Zhang L, Rogers HJ, Parker Y, Duong HK, Lichtin A, Kalaycio ME, Sekeres MA, Mountantonakis SE, Heresi GA, Tiu RV.

Leukemia. 2014 Jul;28(7):1486-93. doi: 10.1038/leu.2014.5. Epub 2014 Jan 10.


STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients.

Jerez A, Clemente MJ, Makishima H, Rajala H, Gómez-Seguí I, Olson T, McGraw K, Przychodzen B, Kulasekararaj A, Afable M, Husseinzadeh HD, Hosono N, LeBlanc F, Lagström S, Zhang D, Ellonen P, Tichelli A, Nissen C, Lichtin AE, Wodnar-Filipowicz A, Mufti GJ, List AF, Mustjoki S, Loughran TP Jr, Maciejewski JP.

Blood. 2013 Oct 3;122(14):2453-9. doi: 10.1182/blood-2013-04-494930. Epub 2013 Aug 7. Erratum in: Blood. 2014 May 22;123(21):3364.


SF3B1 mutations are infrequently found in non-myelodysplastic bone marrow failure syndromes and mast cell diseases but, if present, are associated with the ring sideroblast phenotype.

Visconte V, Tabarroki A, Rogers HJ, Hasrouni E, Traina F, Makishima H, Hamilton BK, Liu Y, O'Keefe C, Lichtin A, Horwitz L, Sekeres MA, Hsieh FH, Tiu RV.

Haematologica. 2013 Sep;98(9):e105-7. doi: 10.3324/haematol.2013.090506. Epub 2013 Jul 5. No abstract available.


A young woman with enlarged lymph nodes.

Husseinzadeh H, Cotta CV, Gordon S, Lichtin A.

Cleve Clin J Med. 2013 May;80(5):276-80. doi: 10.3949/ccjm.80a.12086. No abstract available.


Clinical experiences with ruxolitinib in symptomatic patients with myeloproliferative neoplasm with chronic kidney disease.

Tabarroki A, Visconte V, Rogers HJ, Sekeres MA, Samaras C, Lichtin A, Duong HK, Englehaupt R, Cinalli T, Dodd K, Desamito J, Rouphail B, Altman JK, Stein BL, Tiu RV.

Leuk Lymphoma. 2014 Jan;55(1):213-6. doi: 10.3109/10428194.2013.797086. Epub 2013 Jun 12. No abstract available.


Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.

Traina F, Visconte V, Jankowska AM, Makishima H, O'Keefe CL, Elson P, Han Y, Hsieh FH, Sekeres MA, Mali RS, Kalaycio M, Lichtin AE, Advani AS, Duong HK, Copelan E, Kapur R, Olalla Saad ST, Maciejewski JP, Tiu RV.

PLoS One. 2012;7(8):e43090. doi: 10.1371/journal.pone.0043090. Epub 2012 Aug 15.


Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertension.

Asosingh K, Farha S, Lichtin A, Graham B, George D, Aldred M, Hazen SL, Loyd J, Tuder R, Erzurum SC.

Blood. 2012 Aug 9;120(6):1218-27. doi: 10.1182/blood-2012-03-419275. Epub 2012 Jun 28.


p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies.

Saunthararajah Y, Triozzi P, Rini B, Singh A, Radivoyevitch T, Sekeres M, Advani A, Tiu R, Reu F, Kalaycio M, Copelan E, Hsi E, Lichtin A, Bolwell B.

Semin Oncol. 2012 Feb;39(1):97-108. doi: 10.1053/j.seminoncol.2011.11.011. Review.


A 54-year-old woman with pancytopenia.

Timothy AD, Jegalian A, Lichtin AE.

Cleve Clin J Med. 2011 Dec;78(12):815-20. doi: 10.3949/ccjm.78a.11061. No abstract available.


High levels of zinc-protoporphyrin identify iron metabolic abnormalities in pulmonary arterial hypertension.

Decker I, Ghosh S, Comhair SA, Farha S, Tang WH, Park M, Wang S, Lichtin AE, Erzurum SC.

Clin Transl Sci. 2011 Aug;4(4):253-8. doi: 10.1111/j.1752-8062.2011.00301.x.


Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia.

Clemente MJ, Wlodarski MW, Makishima H, Viny AD, Bretschneider I, Shaik M, Bejanyan N, Lichtin AE, Hsi ED, Paquette RL, Loughran TP Jr, Maciejewski JP.

Blood. 2011 Oct 20;118(16):4384-93. doi: 10.1182/blood-2011-02-338517. Epub 2011 Aug 24. Erratum in: Blood. 2012 Aug 30;120(9):1963. His, Eric D [corrected to Hsi, Eric D].


Efficacy of rabbit anti-thymocyte globulin in severe aplastic anemia.

Afable MG 2nd, Shaik M, Sugimoto Y, Elson P, Clemente M, Makishima H, Sekeres MA, Lichtin A, Advani A, Kalaycio M, Tiu RV, O'Keefe CL, Maciejewski JP.

Haematologica. 2011 Sep;96(9):1269-75. doi: 10.3324/haematol.2011.042622. Epub 2011 May 23.


Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities.

Farha S, Asosingh K, Xu W, Sharp J, George D, Comhair S, Park M, Tang WH, Loyd JE, Theil K, Tubbs R, Hsi E, Lichtin A, Erzurum SC.

Blood. 2011 Mar 31;117(13):3485-93. doi: 10.1182/blood-2010-09-306357. Epub 2011 Jan 21.


Clinical practice guidelines for the use of erythroid-stimulating agents: ASCO, EORTC, NCCN.

Lichtin AE.

Cancer Treat Res. 2011;157:239-48. doi: 10.1007/978-1-4419-7073-2_14. Review. No abstract available.


Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8+ large granular lymphocyte leukemia.

Mohan SR, Clemente MJ, Afable M, Cazzolli HN, Bejanyan N, Wlodarski MW, Lichtin AE, Maciejewski JP.

Haematologica. 2009 Oct;94(10):1407-14. doi: 10.3324/haematol.2009.009191.


How safe are erythropoiesis-stimulating agents?

Lichtin AE.

Cleve Clin J Med. 2008 May;75(5):359-60. No abstract available.


Outcomes of splenectomy in T-cell large granular lymphocyte leukemia with splenomegaly and cytopenia.

Subbiah V, Viny AD, Rosenblatt S, Pohlman B, Lichtin A, Maciejewski JP.

Exp Hematol. 2008 Sep;36(9):1078-83. doi: 10.1016/j.exphem.2008.04.005. Epub 2008 Jun 11.


Chronic B-cell dyscrasias are an important clinical feature of T-LGL leukemia.

Viny AD, Lichtin A, Pohlman B, Loughran T, Maciejewski J.

Leuk Lymphoma. 2008 May;49(5):932-8. doi: 10.1080/10428190801932635.


Bilateral panocular involvement with mantle-cell lymphoma.

Chappelow AV, Singh AD, Perez VL, Lichtin A, Pohlman B, Macklis R.

J Clin Oncol. 2008 Mar 1;26(7):1167. doi: 10.1200/JCO.2007.14.2620. No abstract available.


Clonal predominance of CD8(+) T cells in patients with unexplained neutropenia.

Wlodarski MW, Nearman Z, Jiang Y, Lichtin A, Maciejewski JP.

Exp Hematol. 2008 Mar;36(3):293-300. doi: 10.1016/j.exphem.2007.11.011.


Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial.

Kuter DJ, Bussel JB, Lyons RM, Pullarkat V, Gernsheimer TB, Senecal FM, Aledort LM, George JN, Kessler CM, Sanz MA, Liebman HA, Slovick FT, de Wolf JT, Bourgeois E, Guthrie TH Jr, Newland A, Wasser JS, Hamburg SI, Grande C, Lefrère F, Lichtin AE, Tarantino MD, Terebelo HR, Viallard JF, Cuevas FJ, Go RS, Henry DH, Redner RL, Rice L, Schipperus MR, Guo DM, Nichol JL.

Lancet. 2008 Feb 2;371(9610):395-403. doi: 10.1016/S0140-6736(08)60203-2.


Platelet larceny: spurious hypoxaemia due to extreme thrombocytosis.

Mehta A, Lichtin AE, Vigg A, Parambil JG.

Eur Respir J. 2008 Feb;31(2):469-72. doi: 10.1183/09031936.00039607.


Hypocupremia and bone marrow failure.

Haddad AS, Subbiah V, Lichtin AE, Theil KS, Maciejewski JP.

Haematologica. 2008 Jan;93(1):e1-5. doi: 10.3324/haematol.12121.


Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Clinical Oncology/American Society of Hematology clinical practice guideline update.

Rizzo JD, Somerfield MR, Hagerty KL, Seidenfeld J, Bohlius J, Bennett CL, Cella DF, Djulbegovic B, Goode MJ, Jakubowski AA, Rarick MU, Regan DH, Lichtin AE; American Society of Clinical Oncology; American Society of Hematology.

J Clin Oncol. 2008 Jan 1;26(1):132-49. Epub 2007 Oct 22. Erratum in: J Clin Oncol. 2008 Mar 1;26(7):1192.


Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Hematology/American Society of Clinical Oncology clinical practice guideline update.

Rizzo JD, Somerfield MR, Hagerty KL, Seidenfeld J, Bohlius J, Bennett CL, Cella DF, Djulbegovic B, Goode MJ, Jakubowski AA, Rarick MU, Regan DH, Lichtin AE.

Blood. 2008 Jan 1;111(1):25-41. Epub 2007 Oct 22. Review. Erratum in: Blood. 2008 Apr 1;111(7):3909.


Thyroid disease in patients with idiopathic thrombocytopenia: a cohort study.

Ioachimescu AG, Makdissi A, Lichtin A, Zimmerman RS.

Thyroid. 2007 Nov;17(11):1137-42.


Hemochromatosis-associated gene mutations in patients with myelodysplastic syndromes with refractory anemia with ringed sideroblasts.

Nearman ZP, Szpurka H, Serio B, Warshawksy I, Theil K, Lichtin A, Sekeres MA, Maciejewski JP.

Am J Hematol. 2007 Dec;82(12):1076-9.


High-resolution genomic arrays facilitate detection of novel cryptic chromosomal lesions in myelodysplastic syndromes.

O'Keefe CL, Tiu R, Gondek LP, Powers J, Theil KS, Kalaycio M, Lichtin A, Sekeres MA, Maciejewski JP.

Exp Hematol. 2007 Feb;35(2):240-51.


AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP.

Bussel JB, Kuter DJ, George JN, McMillan R, Aledort LM, Conklin GT, Lichtin AE, Lyons RM, Nieva J, Wasser JS, Wiznitzer I, Kelly R, Chen CF, Nichol JL.

N Engl J Med. 2006 Oct 19;355(16):1672-81. Erratum in: N Engl J Med. 2006 Nov 9;355(19):2054.


The ASH/ASCO clinical guidelines on the use of erythropoietin.

Lichtin A.

Best Pract Res Clin Haematol. 2005;18(3):433-8. Review.


Acute leukemia with a very high leukocyte count: confronting a medical emergency.

Majhail NS, Lichtin AE.

Cleve Clin J Med. 2004 Aug;71(8):633-7. Review.


Clopidogrel and thrombotic thrombocytopenic purpura: no clear case for causality.

Majhail NS, Lichtin AE.

Cleve Clin J Med. 2003 May;70(5):466-70. Review.


Rare coexistence of multiple myeloma with essential thrombocythemia: report of two cases.

Majhail NS, Lichtin AE.

Haematologica. 2003 Apr;88(4):ECR09. No abstract available.


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