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Subclonal STAT3 mutations solidify clonal dominance.

Kerr CM, Clemente MJ, Chomczynski PW, Przychodzen B, Nagata Y, Adema V, Visconte V, Lichtin AE, Mustjoki S, Radivoyevitch T, Sekeres MA, Maciejewski JP.

Blood Adv. 2019 Mar 26;3(6):917-921. doi: 10.1182/bloodadvances.2018027862.


Laparoscopic splenectomy for immune thrombocytopenia (ITP): long-term outcomes of a modern cohort.

Tastaldi L, Krpata DM, Prabhu AS, Petro CC, Haskins IN, Perez AJ, Alkhatib H, Colturato I, Tu C, Lichtin A, Rosen MJ, Rosenblatt S.

Surg Endosc. 2019 Feb;33(2):475-485. doi: 10.1007/s00464-018-6321-y. Epub 2018 Jul 9.


Clinical features and treatment outcomes in large granular lymphocytic leukemia (LGLL).

Sanikommu SR, Clemente MJ, Chomczynski P, Afable MG 2nd, Jerez A, Thota S, Patel B, Hirsch C, Nazha A, Desamito J, Lichtin A, Pohlman B, Sekeres MA, Radivoyevitch T, Maciejewski JP.

Leuk Lymphoma. 2018 Feb;59(2):416-422. doi: 10.1080/10428194.2017.1339880. Epub 2017 Jun 20.


Erythrocytosis due to presumed polycythemia vera.

Patell R, Theil K, Lichtin A.

Cleve Clin J Med. 2016 Sep;83(9):648-53. doi: 10.3949/ccjm.83a.15154. Review. No abstract available.


Thrombotic thrombocytopenic purpura: The role of ADAMTS13.

Rogers HJ, Allen C, Lichtin AE.

Cleve Clin J Med. 2016 Aug;83(8):597-603. doi: 10.3949/ccjm.83a.15009. Review.


Ankle pain in a young woman with Gaucher disease.

Kattoor AJ, Bauer TW, Berkowitz M, Polster JM, Lichtin AE.

Cleve Clin J Med. 2015 Sep;82(9):607-13. doi: 10.3949/ccjm.82a.14108. No abstract available.


Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes.

Saunthararajah Y, Sekeres M, Advani A, Mahfouz R, Durkin L, Radivoyevitch T, Englehaupt R, Juersivich J, Cooper K, Husseinzadeh H, Przychodzen B, Rump M, Hobson S, Earl M, Sobecks R, Dean R, Reu F, Tiu R, Hamilton B, Copelan E, Lichtin A, Hsi E, Kalaycio M, Maciejewski J.

J Clin Invest. 2015 Mar 2;125(3):1043-55. doi: 10.1172/JCI78789. Epub 2015 Jan 26.


Cyclosporine dependent pure red cell aplasia: a case presentation.

Al-Issa K, Visconte V, Rogers HJ, Dembla V, Lichtin AE, Tiu RV.

Blood Cells Mol Dis. 2015 Mar;54(3):281-3. doi: 10.1016/j.bcmd.2014.11.013. Epub 2014 Nov 25. No abstract available.


Screening for SF3B1 mutations is a useful tool to differentiate between acquired clonal and non-clonal sideroblastic anemia.

Visconte V, Tabarroki A, Gerace CJ, Al-Issa K, Hsi ED, Rogers HJ, Sekeres MA, Silver BJ, Lichtin AE, Mukherjee S, Tiu RV.

Leuk Lymphoma. 2015 Jun;56(6):1888-90. doi: 10.3109/10428194.2014.976821. Epub 2014 Nov 14. No abstract available.


Ruxolitinib leads to improvement of pulmonary hypertension in patients with myelofibrosis.

Tabarroki A, Lindner DJ, Visconte V, Zhang L, Rogers HJ, Parker Y, Duong HK, Lichtin A, Kalaycio ME, Sekeres MA, Mountantonakis SE, Heresi GA, Tiu RV.

Leukemia. 2014 Jul;28(7):1486-93. doi: 10.1038/leu.2014.5. Epub 2014 Jan 10.


STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients.

Jerez A, Clemente MJ, Makishima H, Rajala H, Gómez-Seguí I, Olson T, McGraw K, Przychodzen B, Kulasekararaj A, Afable M, Husseinzadeh HD, Hosono N, LeBlanc F, Lagström S, Zhang D, Ellonen P, Tichelli A, Nissen C, Lichtin AE, Wodnar-Filipowicz A, Mufti GJ, List AF, Mustjoki S, Loughran TP Jr, Maciejewski JP.

Blood. 2013 Oct 3;122(14):2453-9. doi: 10.1182/blood-2013-04-494930. Epub 2013 Aug 7. Erratum in: Blood. 2014 May 22;123(21):3364.


SF3B1 mutations are infrequently found in non-myelodysplastic bone marrow failure syndromes and mast cell diseases but, if present, are associated with the ring sideroblast phenotype.

Visconte V, Tabarroki A, Rogers HJ, Hasrouni E, Traina F, Makishima H, Hamilton BK, Liu Y, O'Keefe C, Lichtin A, Horwitz L, Sekeres MA, Hsieh FH, Tiu RV.

Haematologica. 2013 Sep;98(9):e105-7. doi: 10.3324/haematol.2013.090506. Epub 2013 Jul 5. No abstract available.


A young woman with enlarged lymph nodes.

Husseinzadeh H, Cotta CV, Gordon S, Lichtin A.

Cleve Clin J Med. 2013 May;80(5):276-80. doi: 10.3949/ccjm.80a.12086. No abstract available.


Clinical experiences with ruxolitinib in symptomatic patients with myeloproliferative neoplasm with chronic kidney disease.

Tabarroki A, Visconte V, Rogers HJ, Sekeres MA, Samaras C, Lichtin A, Duong HK, Englehaupt R, Cinalli T, Dodd K, Desamito J, Rouphail B, Altman JK, Stein BL, Tiu RV.

Leuk Lymphoma. 2014 Jan;55(1):213-6. doi: 10.3109/10428194.2013.797086. Epub 2013 Jun 12. No abstract available.


Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.

Traina F, Visconte V, Jankowska AM, Makishima H, O'Keefe CL, Elson P, Han Y, Hsieh FH, Sekeres MA, Mali RS, Kalaycio M, Lichtin AE, Advani AS, Duong HK, Copelan E, Kapur R, Olalla Saad ST, Maciejewski JP, Tiu RV.

PLoS One. 2012;7(8):e43090. doi: 10.1371/journal.pone.0043090. Epub 2012 Aug 15.


Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertension.

Asosingh K, Farha S, Lichtin A, Graham B, George D, Aldred M, Hazen SL, Loyd J, Tuder R, Erzurum SC.

Blood. 2012 Aug 9;120(6):1218-27. doi: 10.1182/blood-2012-03-419275. Epub 2012 Jun 28.


p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies.

Saunthararajah Y, Triozzi P, Rini B, Singh A, Radivoyevitch T, Sekeres M, Advani A, Tiu R, Reu F, Kalaycio M, Copelan E, Hsi E, Lichtin A, Bolwell B.

Semin Oncol. 2012 Feb;39(1):97-108. doi: 10.1053/j.seminoncol.2011.11.011. Review.


A 54-year-old woman with pancytopenia.

Timothy AD, Jegalian A, Lichtin AE.

Cleve Clin J Med. 2011 Dec;78(12):815-20. doi: 10.3949/ccjm.78a.11061. No abstract available.


High levels of zinc-protoporphyrin identify iron metabolic abnormalities in pulmonary arterial hypertension.

Decker I, Ghosh S, Comhair SA, Farha S, Tang WH, Park M, Wang S, Lichtin AE, Erzurum SC.

Clin Transl Sci. 2011 Aug;4(4):253-8. doi: 10.1111/j.1752-8062.2011.00301.x.


Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia.

Clemente MJ, Wlodarski MW, Makishima H, Viny AD, Bretschneider I, Shaik M, Bejanyan N, Lichtin AE, Hsi ED, Paquette RL, Loughran TP Jr, Maciejewski JP.

Blood. 2011 Oct 20;118(16):4384-93. doi: 10.1182/blood-2011-02-338517. Epub 2011 Aug 24. Erratum in: Blood. 2012 Aug 30;120(9):1963. His, Eric D [corrected to Hsi, Eric D].

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