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Items: 41

1.

Phase II activity of belinostat (PXD-101), carboplatin, and paclitaxel in women with previously treated ovarian cancer.

Dizon DS, Damstrup L, Finkler NJ, Lassen U, Celano P, Glasspool R, Crowley E, Lichenstein HS, Knoblach P, Penson RT.

Int J Gynecol Cancer. 2012 Jul;22(6):979-86. doi: 10.1097/IGC.0b013e31825736fd.

PMID:
22694911
2.

Activity of the histone deacetylase inhibitor belinostat (PXD101) in preclinical models of prostate cancer.

Qian X, Ara G, Mills E, LaRochelle WJ, Lichenstein HS, Jeffers M.

Int J Cancer. 2008 Mar 15;122(6):1400-10.

3.

Plasma and cerebrospinal fluid pharmacokinetics of the histone deacetylase inhibitor, belinostat (PXD101), in non-human primates.

Warren KE, McCully C, Dvinge H, Tjørnelund J, Sehested M, Lichenstein HS, Balis FM.

Cancer Chemother Pharmacol. 2008 Aug;62(3):433-7. Epub 2007 Oct 25.

PMID:
17960383
4.

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors.

Khan N, Jeffers M, Kumar S, Hackett C, Boldog F, Khramtsov N, Qian X, Mills E, Berghs SC, Carey N, Finn PW, Collins LS, Tumber A, Ritchie JW, Jensen PB, Lichenstein HS, Sehested M.

Biochem J. 2008 Jan 15;409(2):581-9.

PMID:
17868033
5.

Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB.

Pollack VA, Alvarez E, Tse KF, Torgov MY, Xie S, Shenoy SG, MacDougall JR, Arrol S, Zhong H, Gerwien RW, Hahne WF, Senter PD, Jeffers ME, Lichenstein HS, LaRochelle WJ.

Cancer Chemother Pharmacol. 2007 Aug;60(3):423-35. Epub 2007 Jun 1.

PMID:
17541593
6.

Activity of PXD101, a histone deacetylase inhibitor, in preclinical ovarian cancer studies.

Qian X, LaRochelle WJ, Ara G, Wu F, Petersen KD, Thougaard A, Sehested M, Lichenstein HS, Jeffers M.

Mol Cancer Ther. 2006 Aug;5(8):2086-95.

7.

Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells.

van Roeyen CR, Ostendorf T, Denecke B, Bokemeyer D, Behrmann I, Strutz F, Lichenstein HS, LaRochelle WJ, Pena CE, Chaudhuri A, Floege J.

Kidney Int. 2006 Apr;69(8):1393-402.

8.

CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma.

Tse KF, Jeffers M, Pollack VA, McCabe DA, Shadish ML, Khramtsov NV, Hackett CS, Shenoy SG, Kuang B, Boldog FL, MacDougall JR, Rastelli L, Herrmann J, Gallo M, Gazit-Bornstein G, Senter PD, Meyer DL, Lichenstein HS, LaRochelle WJ.

Clin Cancer Res. 2006 Feb 15;12(4):1373-82.

9.

Angioarrestin: a unique angiopoietin-related protein with anti-angiogenic properties.

Dhanabal M, Jeffers M, LaRochelle WJ, Lichenstein HS.

Biochem Biophys Res Commun. 2005 Jul 29;333(2):308-15. Review.

PMID:
15950186
10.

Recombinant semaphorin 6A-1 ectodomain inhibits in vivo growth factor and tumor cell line-induced angiogenesis.

Dhanabal M, Wu F, Alvarez E, McQueeney KD, Jeffers M, MacDougall J, Boldog FL, Hackett C, Shenoy S, Khramtsov N, Weiner J, Lichenstein HS, LaRochelle WJ.

Cancer Biol Ther. 2005 Jun;4(6):659-68. Epub 2005 Jun 11.

PMID:
15917651
11.

Preclinical characterization of CG53135 (FGF-20) in radiation and concomitant chemotherapy/radiation-induced oral mucositis.

Alvarez E, Fey EG, Valax P, Yim Z, Peterson JD, Mesri M, Jeffers M, Dindinger M, Twomlow N, Ghatpande A, LaRochelle WJ, Sonis ST, Lichenstein HS.

Clin Cancer Res. 2003 Aug 15;9(9):3454-61.

12.

A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis.

Ostendorf T, van Roeyen CR, Peterson JD, Kunter U, Eitner F, Hamad AJ, Chan G, Jia XC, Macaluso J, Gazit-Bornstein G, Keyt BA, Lichenstein HS, LaRochelle WJ, Floege J.

J Am Soc Nephrol. 2003 Sep;14(9):2237-47.

13.

A novel human fibroblast growth factor treats experimental intestinal inflammation.

Jeffers M, McDonald WF, Chillakuru RA, Yang M, Nakase H, Deegler LL, Sylander ED, Rittman B, Bendele A, Sartor RB, Lichenstein HS.

Gastroenterology. 2002 Oct;123(4):1151-62.

PMID:
12360478
14.

Fibroblast growth factors in cancer: therapeutic possibilities.

Jeffers M, LaRochelle WJ, Lichenstein HS.

Expert Opin Ther Targets. 2002 Aug;6(4):469-82. Review.

PMID:
12223061
15.

Angioarrestin: an antiangiogenic protein with tumor-inhibiting properties.

Dhanabal M, LaRochelle WJ, Jeffers M, Herrmann J, Rastelli L, McDonald WF, Chillakuru RA, Yang M, Boldog FL, Padigaru M, McQueeney KD, Wu F, Minskoff SA, Shimkets RA, Lichenstein HS.

Cancer Res. 2002 Jul 1;62(13):3834-41.

16.

Platelet-derived growth factor D: tumorigenicity in mice and dysregulated expression in human cancer.

LaRochelle WJ, Jeffers M, Corvalan JR, Jia XC, Feng X, Vanegas S, Vickroy JD, Yang XD, Chen F, Gazit G, Mayotte J, Macaluso J, Rittman B, Wu F, Dhanabal M, Herrmann J, Lichenstein HS.

Cancer Res. 2002 May 1;62(9):2468-73.

17.

PDGF-D, a new protease-activated growth factor.

LaRochelle WJ, Jeffers M, McDonald WF, Chillakuru RA, Giese NA, Lokker NA, Sullivan C, Boldog FL, Yang M, Vernet C, Burgess CE, Fernandes E, Deegler LL, Rittman B, Shimkets J, Shimkets RA, Rothberg JM, Lichenstein HS.

Nat Cell Biol. 2001 May;3(5):517-21.

PMID:
11331882
18.

Identification of a novel human fibroblast growth factor and characterization of its role in oncogenesis.

Jeffers M, Shimkets R, Prayaga S, Boldog F, Yang M, Burgess C, Fernandes E, Rittman B, Shimkets J, LaRochelle WJ, Lichenstein HS.

Cancer Res. 2001 Apr 1;61(7):3131-8.

19.

Neutrophil activation by bacterial lipoprotein versus lipopolysaccharide: differential requirements for serum and CD14.

Soler-Rodriguez AM, Zhang H, Lichenstein HS, Qureshi N, Niesel DW, Crowe SE, Peterson JW, Klimpel GR.

J Immunol. 2000 Mar 1;164(5):2674-83.

20.

Cytokine mRNA decay is accelerated by an inhibitor of p38-mitogen-activated protein kinase.

Wang SW, Pawlowski J, Wathen ST, Kinney SD, Lichenstein HS, Manthey CL.

Inflamm Res. 1999 Oct;48(10):533-8.

PMID:
10563470
21.

Purification and activation of recombinant p38 isoforms alpha, beta, gamma, and delta.

Keesler GA, Bray J, Hunt J, Johnson DA, Gleason T, Yao Z, Wang SW, Parker C, Yamane H, Cole C, Lichenstein HS.

Protein Expr Purif. 1998 Nov;14(2):221-8.

PMID:
9790884
22.

Soluble CD14(1-152) confers responsiveness to both lipoarabinomannan and lipopolysaccharide in a novel HL-60 cell bioassay.

Yu W, Soprana E, Cosentino G, Volta M, Lichenstein HS, Viale G, Vercelli D.

J Immunol. 1998 Oct 15;161(8):4244-51.

23.

Identification of stathmin as a novel substrate for p38 delta.

Parker CG, Hunt J, Diener K, McGinley M, Soriano B, Keesler GA, Bray J, Yao Z, Wang XS, Kohno T, Lichenstein HS.

Biochem Biophys Res Commun. 1998 Aug 28;249(3):791-6.

PMID:
9731215
24.

Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases.

Rosendahl MS, Ko SC, Long DL, Brewer MT, Rosenzweig B, Hedl E, Anderson L, Pyle SM, Moreland J, Meyers MA, Kohno T, Lyons D, Lichenstein HS.

J Biol Chem. 1997 Sep 26;272(39):24588-93.

25.

Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase.

Wang XS, Diener K, Manthey CL, Wang S, Rosenzweig B, Bray J, Delaney J, Cole CN, Chan-Hui PY, Mantlo N, Lichenstein HS, Zukowski M, Yao Z.

J Biol Chem. 1997 Sep 19;272(38):23668-74.

26.

Dual effects of soluble CD14 on LPS priming of neutrophils.

Troelstra A, Giepmans BN, Van Kessel KP, Lichenstein HS, Verhoef J, Van Strijp JA.

J Leukoc Biol. 1997 Feb;61(2):173-8.

PMID:
9021923
28.

Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14.

Hailman E, Vasselon T, Kelley M, Busse LA, Hu MC, Lichenstein HS, Detmers PA, Wright SD.

J Immunol. 1996 Jun 1;156(11):4384-90.

PMID:
8666811
29.

Molecules from Staphylococcus aureus that bind CD14 and stimulate innate immune responses.

Kusunoki T, Hailman E, Juan TS, Lichenstein HS, Wright SD.

J Exp Med. 1995 Dec 1;182(6):1673-82.

30.

Identification of a domain in soluble CD14 essential for lipopolysaccharide (LPS) signaling but not LPS binding.

Juan TS, Hailman E, Kelley MJ, Wright SD, Lichenstein HS.

J Biol Chem. 1995 Jul 21;270(29):17237-42.

31.

Influence of CD14, LBP and BPI in the monocyte response to LPS of different polysaccharide chain length.

Jahr TG, Sundan A, Lichenstein HS, Espevik T.

Scand J Immunol. 1995 Jul;42(1):119-27.

PMID:
7543211
32.

Identification of a lipopolysaccharide binding domain in CD14 between amino acids 57 and 64.

Juan TS, Hailman E, Kelley MJ, Busse LA, Davy E, Empig CJ, Narhi LO, Wright SD, Lichenstein HS.

J Biol Chem. 1995 Mar 10;270(10):5219-24.

33.

CD14: physical properties and identification of an exposed site that is protected by lipopolysaccharide.

McGinley MD, Narhi LO, Kelley MJ, Davy E, Robinson J, Rohde MF, Wright SD, Lichenstein HS.

J Biol Chem. 1995 Mar 10;270(10):5213-8.

34.

P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin.

Moore KL, Patel KD, Bruehl RE, Li F, Johnson DA, Lichenstein HS, Cummings RD, Bainton DF, McEver RP.

J Cell Biol. 1995 Feb;128(4):661-71.

35.

Soluble CD14 truncated at amino acid 152 binds lipopolysaccharide (LPS) and enables cellular response to LPS.

Juan TS, Kelley MJ, Johnson DA, Busse LA, Hailman E, Wright SD, Lichenstein HS.

J Biol Chem. 1995 Jan 20;270(3):1382-7.

36.

The P-selectin glycoprotein ligand from human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamine.

Moore KL, Eaton SF, Lyons DE, Lichenstein HS, Cummings RD, McEver RP.

J Biol Chem. 1994 Sep 16;269(37):23318-27.

37.

Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family.

Lichenstein HS, Lyons DE, Wurfel MM, Johnson DA, McGinley MD, Leidli JC, Trollinger DB, Mayer JP, Wright SD, Zukowski MM.

J Biol Chem. 1994 Jul 8;269(27):18149-54.

38.

Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.

Hailman E, Lichenstein HS, Wurfel MM, Miller DS, Johnson DA, Kelley M, Busse LA, Zukowski MM, Wright SD.

J Exp Med. 1994 Jan 1;179(1):269-77.

39.

Cloning and characterization of a gene encoding extracellular metalloprotease from Streptomyces lividans.

Lichenstein HS, Busse LA, Smith GA, Narhi LO, McGinley MO, Rohde MF, Katzowitz JL, Zukowski MM.

Gene. 1992 Feb 1;111(1):125-30.

PMID:
1547948
40.

Cloning and nucleotide sequence of the N-acetylmuramidase M1-encoding gene from Streptomyces globisporus.

Lichenstein HS, Hastings AE, Langley KE, Mendiaz EA, Rohde MF, Elmore R, Zukowski MM.

Gene. 1990 Mar 30;88(1):81-6.

PMID:
2341041
41.

Repression and catabolite gene activation in the araBAD operon.

Lichenstein HS, Hamilton EP, Lee N.

J Bacteriol. 1987 Feb;169(2):811-22.

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