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Items: 1 to 50 of 192

1.

Revisiting the Hallmarks of Aging to Identify Markers of Biological Age.

Guerville F, De Souto Barreto P, Ader I, Andrieu S, Casteilla L, Dray C, Fazilleau N, Guyonnet S, Langin D, Liblau R, Parini A, Valet P, Vergnolle N, Rolland Y, Vellas B.

J Prev Alzheimers Dis. 2020;7(1):56-64. doi: 10.14283/jpad.2019.50.

PMID:
32010927
2.

Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells.

Malviya M, Saoudi A, Bauer J, Fillatreau S, Liblau R.

J Autoimmun. 2020 Mar;108:102401. doi: 10.1016/j.jaut.2020.102401. Epub 2020 Jan 13.

PMID:
31948790
3.

CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.

Gross CC, Meyer C, Bhatia U, Yshii L, Kleffner I, Bauer J, Tröscher AR, Schulte-Mecklenbeck A, Herich S, Schneider-Hohendorf T, Plate H, Kuhlmann T, Schwaninger M, Brück W, Pawlitzki M, Laplaud DA, Loussouarn D, Parratt J, Barnett M, Buckland ME, Hardy TA, Reddel SW, Ringelstein M, Dörr J, Wildemann B, Kraemer M, Lassmann H, Höftberger R, Beltrán E, Dornmair K, Schwab N, Klotz L, Meuth SG, Martin-Blondel G, Wiendl H, Liblau R.

Nat Commun. 2019 Dec 18;10(1):5779. doi: 10.1038/s41467-019-13593-5.

4.

Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment.

Bassetti CLA, Adamantidis A, Burdakov D, Han F, Gay S, Kallweit U, Khatami R, Koning F, Kornum BR, Lammers GJ, Liblau RS, Luppi PH, Mayer G, Pollmächer T, Sakurai T, Sallusto F, Scammell TE, Tafti M, Dauvilliers Y.

Nat Rev Neurol. 2019 Sep;15(9):519-539. doi: 10.1038/s41582-019-0226-9. Epub 2019 Jul 19. Review.

PMID:
31324898
5.

Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons.

Salvioni A, Belloy M, Lebourg A, Bassot E, Cantaloube-Ferrieu V, Vasseur V, Blanié S, Liblau RS, Suberbielle E, Robey EA, Blanchard N.

Cell Rep. 2019 Jun 11;27(11):3254-3268.e8. doi: 10.1016/j.celrep.2019.05.051.

6.

Treatment of Progressive Multifocal Leukoencephalopathy with Nivolumab.

Walter O, Treiner E, Bonneville F, Mengelle C, Vergez F, Lerebours F, Delobel P, Liblau R, Martin-Blondel G; Immune Checkpoint Inhibitors in PML Study Group.

N Engl J Med. 2019 Apr 25;380(17):1674-1676. doi: 10.1056/NEJMc1816198. Epub 2019 Apr 10. No abstract available.

PMID:
30969500
7.

Shared T cell receptor chains in blood memory CD4+ T cells of narcolepsy type 1 patients.

Beltrán E, Nguyen XH, Quériault C, Barateau L, Dauvilliers Y, Dornmair K, Liblau RS.

J Autoimmun. 2019 Jun;100:1-6. doi: 10.1016/j.jaut.2019.03.010. Epub 2019 Apr 2.

PMID:
30948158
8.

IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration.

Yshii L, Pignolet B, Mauré E, Pierau M, Brunner-Weinzierl M, Hartley O, Bauer J, Liblau R.

JCI Insight. 2019 Apr 4;4(7). pii: 127001. doi: 10.1172/jci.insight.127001. eCollection 2019 Apr 4.

9.

[An autoimmune basis for narcolepsy type 1?]

Chabod M, Khajavi L, Liblau RS.

Med Sci (Paris). 2019 Mar;35(3):204-207. doi: 10.1051/medsci/2019041. Epub 2019 Apr 1. French. No abstract available.

PMID:
30931901
10.

Put to sleep by immune cells.

Liblau RS.

Nature. 2018 Oct;562(7725):46-48. doi: 10.1038/d41586-018-06666-w. No abstract available.

PMID:
30275550
11.

Circulating follicular helper T cells exhibit reduced ICOS expression and impaired function in narcolepsy type 1 patients.

Nguyen XH, Dauvilliers Y, Quériault C, Perals C, Romieu-Mourez R, Paulet PE, Bernard-Valnet R, Fazilleau N, Liblau R.

J Autoimmun. 2018 Nov;94:134-142. doi: 10.1016/j.jaut.2018.07.021. Epub 2018 Aug 6.

PMID:
30104107
12.

The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells.

Machado-Santos J, Saji E, Tröscher AR, Paunovic M, Liblau R, Gabriely G, Bien CG, Bauer J, Lassmann H.

Brain. 2018 Jul 1;141(7):2066-2082. doi: 10.1093/brain/awy151.

13.

ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis.

Montalban X, Gold R, Thompson AJ, Otero-Romero S, Amato MP, Chandraratna D, Clanet M, Comi G, Derfuss T, Fazekas F, Hartung HP, Havrdova E, Hemmer B, Kappos L, Liblau R, Lubetzki C, Marcus E, Miller DH, Olsson T, Pilling S, Selmaj K, Siva A, Sorensen PS, Sormani MP, Thalheim C, Wiendl H, Zipp F.

Mult Scler. 2018 Feb;24(2):96-120. doi: 10.1177/1352458517751049. Epub 2018 Jan 20. Erratum in: Mult Scler. 2020 Feb 4;:1352458520906383.

PMID:
29353550
14.

ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis.

Montalban X, Gold R, Thompson AJ, Otero-Romero S, Amato MP, Chandraratna D, Clanet M, Comi G, Derfuss T, Fazekas F, Hartung HP, Havrdova E, Hemmer B, Kappos L, Liblau R, Lubetzki C, Marcus E, Miller DH, Olsson T, Pilling S, Selmaj K, Siva A, Sorensen PS, Sormani MP, Thalheim C, Wiendl H, Zipp F.

Eur J Neurol. 2018 Feb;25(2):215-237. doi: 10.1111/ene.13536. Epub 2018 Jan 19. Erratum in: Eur J Neurol. 2018 Mar;25(3):605.

PMID:
29352526
15.

Prediction of natalizumab anti-drug antibodies persistency.

Deisenhammer F, Jank M, Lauren A, Sjödin A, Ryner M, Fogdell-Hahn A, Sievers C, Lindberg R, Jensen PE, Sellebjerg F, Christodoulou L, Birchler M, Pallardy M, Auer M, Liblau R; ABIRISK consortium.

Mult Scler. 2019 Mar;25(3):392-398. doi: 10.1177/1352458517753721. Epub 2018 Jan 16.

PMID:
29336205
16.

Inflammatory CNS disease caused by immune checkpoint inhibitors: status and perspectives.

Yshii LM, Hohlfeld R, Liblau RS.

Nat Rev Neurol. 2017 Dec;13(12):755-763. doi: 10.1038/nrneurol.2017.144. Epub 2017 Nov 6. Review.

PMID:
29104289
17.

Hepatic T Cell Tolerance Induction in An Inflammatory Environment.

Dywicki J, Noyan F, Misslitz AC, Hapke M, Galla M, Schlue J, Liblau RS, Taubert R, Manns MP, Jaeckel E, Hardtke-Wolenski M.

Dig Dis. 2018;36(2):156-166. doi: 10.1159/000481341. Epub 2017 Oct 12.

PMID:
29020680
18.

Narcolepsy Type 1 as an Autoimmune Disorder: Evidence, and Implications for Pharmacological Treatment.

Barateau L, Liblau R, Peyron C, Dauvilliers Y.

CNS Drugs. 2017 Oct;31(10):821-834. doi: 10.1007/s40263-017-0464-6. Review.

PMID:
28940143
19.

Environmental modifiable risk factors for multiple sclerosis: Report from the 2016 ECTRIMS focused workshop.

Amato MP, Derfuss T, Hemmer B, Liblau R, Montalban X, Soelberg Sørensen P, Miller DH; 2016 ECTRIMS Focused Workshop Group.

Mult Scler. 2017 Jan 6:1352458516686847. doi: 10.1177/1352458516686847. [Epub ahead of print]

20.

CD4+ and CD8+ T cells are both needed to induce paraneoplastic neurological disease in a mouse model.

Gebauer C, Pignolet B, Yshii L, Mauré E, Bauer J, Liblau R.

Oncoimmunology. 2016 Dec 9;6(2):e1260212. doi: 10.1080/2162402X.2016.1260212. eCollection 2017.

21.

Endothelial cells and lymphatics at the interface between the immune and central nervous systems: implications for multiple sclerosis.

Meyer C, Martin-Blondel G, Liblau RS.

Curr Opin Neurol. 2017 Jun;30(3):222-230. doi: 10.1097/WCO.0000000000000454. Review.

PMID:
28323646
22.

A Fashi Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation.

Menezes SM, Leal FE, Dierckx T, Khouri R, Decanine D, Silva-Santos G, Schnitman SV, Kruschewsky R, López G, Alvarez C, Talledo M, Gotuzzo E, Nixon DF, Vercauteren J, Brassat D, Liblau R, Vandamme AM, Galvão-Castro B, Van Weyenbergh J.

Front Immunol. 2017 Feb 14;8:97. doi: 10.3389/fimmu.2017.00097. eCollection 2017.

23.

Narcolepsy Type 1 Is Associated with a Systemic Increase and Activation of Regulatory T Cells and with a Systemic Activation of Global T Cells.

Lecendreux M, Churlaud G, Pitoiset F, Regnault A, Tran TA, Liblau R, Klatzmann D, Rosenzwajg M.

PLoS One. 2017 Jan 20;12(1):e0169836. doi: 10.1371/journal.pone.0169836. eCollection 2017.

24.

High-dimensional single-cell analysis reveals the immune signature of narcolepsy.

Hartmann FJ, Bernard-Valnet R, Quériault C, Mrdjen D, Weber LM, Galli E, Krieg C, Robinson MD, Nguyen XH, Dauvilliers Y, Liblau RS, Becher B.

J Exp Med. 2016 Nov 14;213(12):2621-2633. Epub 2016 Nov 7.

25.

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes.

Stienne C, Michieletto MF, Benamar M, Carrié N, Bernard I, Nguyen XH, Lippi Y, Duguet F, Liblau RS, Hedrick SM, Saoudi A, Dejean AS.

Immunity. 2016 Oct 18;45(4):774-787. doi: 10.1016/j.immuni.2016.09.010. Epub 2016 Oct 11.

26.

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice.

Bernard-Valnet R, Yshii L, Quériault C, Nguyen XH, Arthaud S, Rodrigues M, Canivet A, Morel AL, Matthys A, Bauer J, Pignolet B, Dauvilliers Y, Peyron C, Liblau RS.

Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10956-61. doi: 10.1073/pnas.1603325113. Epub 2016 Sep 12.

27.

CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model.

Yshii LM, Gebauer CM, Pignolet B, Mauré E, Quériault C, Pierau M, Saito H, Suzuki N, Brunner-Weinzierl M, Bauer J, Liblau R.

Brain. 2016 Nov 1;139(11):2923-2934. doi: 10.1093/brain/aww225.

PMID:
27604307
28.

A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation.

Kassem S, Gaud G, Bernard I, Benamar M, Dejean AS, Liblau R, Fournié GJ, Colacios C, Malissen B, Saoudi A.

PLoS Genet. 2016 Jul 20;12(7):e1006185. doi: 10.1371/journal.pgen.1006185. eCollection 2016 Jul.

29.

Myelin oligodendrocyte glycoprotein induces incomplete tolerance of CD4(+) T cells specific for both a myelin and a neuronal self-antigen in mice.

Lucca LE, Axisa PP, Aloulou M, Perals C, Ramadan A, Rufas P, Kyewski B, Derbinski J, Fazilleau N, Mars LT, Liblau RS.

Eur J Immunol. 2016 Sep;46(9):2247-59. doi: 10.1002/eji.201646416. Epub 2016 Jul 21.

30.

Thymus-Derived Regulatory T Cells Are Positively Selected on Natural Self-Antigen through Cognate Interactions of High Functional Avidity.

Kieback E, Hilgenberg E, Stervbo U, Lampropoulou V, Shen P, Bunse M, Jaimes Y, Boudinot P, Radbruch A, Klemm U, Kühl AA, Liblau R, Hoevelmeyer N, Anderton SM, Uckert W, Fillatreau S.

Immunity. 2016 May 17;44(5):1114-26. doi: 10.1016/j.immuni.2016.04.018.

31.

Vaccine-associated inflammatory diseases of the central nervous system: from signals to causation.

Nguyen XH, Saoudi A, Liblau RS.

Curr Opin Neurol. 2016 Jun;29(3):362-71. doi: 10.1097/WCO.0000000000000318. Review.

PMID:
27023738
32.

In situ expansion of T cells that recognize distinct self-antigens sustains autoimmunity in the CNS.

Ramadan A, Lucca LE, Carrié N, Desbois S, Axisa PP, Hayder M, Bauer J, Liblau RS, Mars LT.

Brain. 2016 May;139(Pt 5):1433-46. doi: 10.1093/brain/aww032. Epub 2016 Mar 21.

PMID:
27000832
33.

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells.

Aloulou M, Carr EJ, Gador M, Bignon A, Liblau RS, Fazilleau N, Linterman MA.

Nat Commun. 2016 Jan 28;7:10579. doi: 10.1038/ncomms10579.

34.

CCR5 blockade for neuroinflammatory diseases--beyond control of HIV.

Martin-Blondel G, Brassat D, Bauer J, Lassmann H, Liblau RS.

Nat Rev Neurol. 2016 Feb;12(2):95-105. doi: 10.1038/nrneurol.2015.248. Epub 2016 Jan 18. Review.

PMID:
26782333
35.

Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity.

Tafti M, Lammers GJ, Dauvilliers Y, Overeem S, Mayer G, Nowak J, Pfister C, Dubois V, Eliaou JF, Eberhard HP, Liblau R, Wierzbicka A, Geisler P, Bassetti CL, Mathis J, Lecendreux M, Khatami R, Heinzer R, Haba-Rubio J, Feketeova E, Baumann CR, Kutalik Z, Tiercy JM.

Sleep. 2016 Mar 1;39(3):581-7. doi: 10.5665/sleep.5532.

36.

Mucosal-Associated Invariant T Cells in Multiple Sclerosis: The Jury is Still Out.

Treiner E, Liblau RS.

Front Immunol. 2015 Sep 30;6:503. doi: 10.3389/fimmu.2015.00503. eCollection 2015. Review.

37.

Phosphorus-Based Dendrimer ABP Treats Neuroinflammation by Promoting IL-10-Producing CD4(+) T Cells.

Hayder M, Varilh M, Turrin CO, Saoudi A, Caminade AM, Poupot R, Liblau RS.

Biomacromolecules. 2015 Nov 9;16(11):3425-33. doi: 10.1021/acs.biomac.5b00643. Epub 2015 Oct 7.

PMID:
26397709
38.

Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1-integrin.

Martin-Blondel G, Pignolet B, Tietz S, Yshii L, Gebauer C, Perinat T, Van Weddingen I, Blatti C, Engelhardt B, Liblau R.

Eur J Immunol. 2015 Dec;45(12):3302-12. doi: 10.1002/eji.201545632. Epub 2015 Oct 6.

39.

Neurons and T cells: Understanding this interaction for inflammatory neurological diseases.

Yshii L, Gebauer C, Bernard-Valnet R, Liblau R.

Eur J Immunol. 2015 Oct;45(10):2712-20. doi: 10.1002/eji.201545759. Epub 2015 Sep 23. Review.

40.

[Migration and pathogenicity of CD8 T cells in central nervous system diseases].

Martin-Blondel G, Pignolet B, Liblau RS.

Med Sci (Paris). 2015 Aug-Sep;31(8-9):748-55. doi: 10.1051/medsci/20153108013. Epub 2015 Sep 4. Review. French.

41.

Innate and adaptive immune responses in the CNS.

Waisman A, Liblau RS, Becher B.

Lancet Neurol. 2015 Sep;14(9):945-55. doi: 10.1016/S1474-4422(15)00141-6. Review.

PMID:
26293566
42.

Consensus nomenclature for CD8+ T cell phenotypes in cancer.

Apetoh L, Smyth MJ, Drake CG, Abastado JP, Apte RN, Ayyoub M, Blay JY, Bonneville M, Butterfield LH, Caignard A, Castelli C, Cavallo F, Celis E, Chen L, Colombo MP, Comin-Anduix B, Coukos G, Dhodapkar MV, Dranoff G, Frazer IH, Fridman WH, Gabrilovich DI, Gilboa E, Gnjatic S, Jäger D, Kalinski P, Kaufman HL, Kiessling R, Kirkwood J, Knuth A, Liblau R, Lotze MT, Lugli E, Marincola F, Melero I, Melief CJ, Mempel TR, Mittendorf EA, Odun K, Overwijk WW, Palucka AK, Parmiani G, Ribas A, Romero P, Schreiber RD, Schuler G, Srivastava PK, Tartour E, Valmori D, van der Burg SH, van der Bruggen P, van den Eynde BJ, Wang E, Zou W, Whiteside TL, Speiser DE, Pardoll DM, Restifo NP, Anderson AC.

Oncoimmunology. 2015 Feb 25;4(4):e998538. eCollection 2015 Apr.

43.

Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.

Rouhani SJ, Eccles JD, Riccardi P, Peske JD, Tewalt EF, Cohen JN, Liblau R, Mäkinen T, Engelhard VH.

Nat Commun. 2015 Apr 10;6:6771. doi: 10.1038/ncomms7771.

44.

Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy.

Liblau RS, Vassalli A, Seifinejad A, Tafti M.

Lancet Neurol. 2015 Mar;14(3):318-28. doi: 10.1016/S1474-4422(14)70218-2. Epub 2015 Feb 16. Review.

PMID:
25728441
45.

Neuromyelitis optica: a positive appraisal of seronegative cases.

Bernard-Valnet R, Liblau RS, Vukusic S, Marignier R.

Eur J Neurol. 2015 Dec;22(12):1511-8, e82-3. doi: 10.1111/ene.12679. Epub 2015 Feb 16. Review.

PMID:
25689634
46.

Therapeutic use of CCR5 antagonists is supported by strong expression of CCR5 on CD8(+) T cells in progressive multifocal leukoencephalopathy-associated immune reconstitution inflammatory syndrome.

Martin-Blondel G, Bauer J, Uro-Coste E, Biotti D, Averseng-Peaureaux D, Fabre N, Dumas H, Bonneville F, Lassmann H, Marchou B, Liblau RS, Brassat D.

Acta Neuropathol. 2015 Mar;129(3):463-5. doi: 10.1007/s00401-015-1383-6. Epub 2015 Jan 15. No abstract available.

PMID:
25589222
47.

Immunotherapy of AD: Alum Demain?

Liblau R, Saoudi A.

J Prev Alzheimers Dis. 2015;2(2):80-81. doi: 10.14283/jpad.2015.64. No abstract available.

PMID:
29231228
48.

Classification of current anticancer immunotherapies.

Galluzzi L, Vacchelli E, Bravo-San Pedro JM, Buqué A, Senovilla L, Baracco EE, Bloy N, Castoldi F, Abastado JP, Agostinis P, Apte RN, Aranda F, Ayyoub M, Beckhove P, Blay JY, Bracci L, Caignard A, Castelli C, Cavallo F, Celis E, Cerundolo V, Clayton A, Colombo MP, Coussens L, Dhodapkar MV, Eggermont AM, Fearon DT, Fridman WH, Fučíková J, Gabrilovich DI, Galon J, Garg A, Ghiringhelli F, Giaccone G, Gilboa E, Gnjatic S, Hoos A, Hosmalin A, Jäger D, Kalinski P, Kärre K, Kepp O, Kiessling R, Kirkwood JM, Klein E, Knuth A, Lewis CE, Liblau R, Lotze MT, Lugli E, Mach JP, Mattei F, Mavilio D, Melero I, Melief CJ, Mittendorf EA, Moretta L, Odunsi A, Okada H, Palucka AK, Peter ME, Pienta KJ, Porgador A, Prendergast GC, Rabinovich GA, Restifo NP, Rizvi N, Sautès-Fridman C, Schreiber H, Seliger B, Shiku H, Silva-Santos B, Smyth MJ, Speiser DE, Spisek R, Srivastava PK, Talmadge JE, Tartour E, Van Der Burg SH, Van Den Eynde BJ, Vile R, Wagner H, Weber JS, Whiteside TL, Wolchok JD, Zitvogel L, Zou W, Kroemer G.

Oncotarget. 2014 Dec 30;5(24):12472-508. Review.

49.

[Editorial].

Antoine JC, Liblau R, Lubetzki C.

Rev Neurol (Paris). 2014 Oct;170(10):559-60. doi: 10.1016/j.neurol.2014.09.001. French. No abstract available.

PMID:
25280980
50.

From classic to spontaneous and humanized models of multiple sclerosis: impact on understanding pathogenesis and drug development.

Ben-Nun A, Kaushansky N, Kawakami N, Krishnamoorthy G, Berer K, Liblau R, Hohlfeld R, Wekerle H.

J Autoimmun. 2014 Nov;54:33-50. doi: 10.1016/j.jaut.2014.06.004. Epub 2014 Aug 28. Review.

PMID:
25175979

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