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A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function.

Trubiroha A, Gillotay P, Giusti N, Gacquer D, Libert F, Lefort A, Haerlingen B, De Deken X, Opitz R, Costagliola S.

Sci Rep. 2018 Apr 4;8(1):5647. doi: 10.1038/s41598-018-24036-4.


Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution.

Dom G, Frank S, Floor S, Kehagias P, Libert F, Hoang C, Andry G, Spinette A, Craciun L, de Saint Aubin N, Tresallet C, Tissier F, Savagner F, Majjaj S, Gutierrez-Roelens I, Marbaix E, Dumont JE, Maenhaut C.

Oncotarget. 2017 Dec 8;9(12):10343-10359. doi: 10.18632/oncotarget.23130. eCollection 2018 Feb 13.


Genetic Analysis of Mu and Kappa Opioid Receptor and COMT Enzyme in Cancer Pain Tunisian Patients Under Opioid Treatment.

Chatti I, Woillard JB, Mili A, Creveaux I, Ben Charfeddine I, Feki J, Langlais S, Ben Fatma L, Saad A, Gribaa M, Libert F.

Iran J Public Health. 2017 Dec;46(12):1704-1711.


Agomelatine: a new opportunity to reduce neuropathic pain-preclinical evidence.

Chenaf C, Chapuy E, Libert F, Marchand F, Courteix C, Bertrand M, Gabriel C, Mocaër E, Eschalier A, Authier N.

Pain. 2017 Jan;158(1):149-160.


[Therapeutic drug monitoring of olanzapine].

Djerada Z, Brousse G, Niel P, Llorca PM, Eschalier A, Bentue-Ferrer D, Libert F; groupe suivi thérapeutique pharmacologique de la Société française de pharmacologie et de thérapeutique.

Therapie. 2016 Oct 25. pii: S0040-5957(16)30042-7. doi: 10.2515/therapie/2015040. [Epub ahead of print] French.


[Therapeutic drug monitoring of clozapine].

Djerada Z, Daviet F, Llorca PM, Eschalier A, Saint-Marcoux F, Bentué-Ferrer D, Libert F; Groupe suivi thérapeutique pharmacologique de la Société française de pharmacologie et de thérapeutique.

Therapie. 2016 Aug 24. pii: S0040-5957(16)31132-5. doi: 10.2515/therapie/2015041. [Epub ahead of print] French.


Increasing spinal 5-HT2A receptor responsiveness mediates anti-allodynic effect and potentiates fluoxetine efficacy in neuropathic rats. Evidence for GABA release.

Dupuis A, Wattiez AS, Pinguet J, Richard D, Libert F, Chalus M, Aissouni Y, Sion B, Ardid D, Marin P, Eschalier A, Courteix C.

Pharmacol Res. 2017 Apr;118:93-103. doi: 10.1016/j.phrs.2016.09.021. Epub 2016 Sep 20.


Pharmacogenomics in pain treatment.

Peiró AM, Planelles B, Juhasz G, Bagdy G, Libert F, Eschalier A, Busserolles J, Sperlagh B, Llerena A.

Drug Metab Pers Ther. 2016 Sep 1;31(3):131-42. doi: 10.1515/dmpt-2016-0005. Review.


Association of the OPRM1 and COMT genes' polymorphisms with the efficacy of morphine in Tunisian cancer patients: Impact of the high genetic heterogeneity in Tunisia?

Chatti I, Creveaux I, Woillard JB, Langlais S, Amara A, Ben Fatma L, Saad A, Gribaa M, Libert F.

Therapie. 2016 Oct;71(5):507-513. doi: 10.1016/j.therap.2016.04.004. Epub 2016 May 18.


[Practical information for therapeutic drug monitoring of the most common compounds].

Saint-Marcoux F, Libert F; groupe Suivi thérapeutique pharmacologique de la Société française de pharmacologie et de thérapeutique.

Therapie. 2016 Sep;71(4):405-34. doi: 10.1016/j.therap.2016.01.007. Epub 2016 May 4. French.


Ultrasonographic Pattern of Testicular Metastasis of Clear Cell Renal Cell Carcinoma with Pathological Correlation.

Libert F, Cabri-Wiltzer M, Dardenne E, Draguet AP, Puttemans T.

J Belg Soc Radiol. 2016 Mar 31;100(1):54. doi: 10.5334/jbr-btr.937.


Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage.

Fernandez Vallone V, Leprovots M, Strollo S, Vasile G, Lefort A, Libert F, Vassart G, Garcia MI.

Development. 2016 May 1;143(9):1452-63. doi: 10.1242/dev.131490. Epub 2016 Mar 17.


Genome-wide analysis of TIAR RNA ligands in mouse macrophages before and after LPS stimulation.

Kharraz Y, Lefort A, Libert F, Mann CJ, Gueydan C, Kruys V.

Genom Data. 2016 Feb 8;7:297-300. doi: 10.1016/j.gdata.2016.02.007. eCollection 2016 Mar.


Fully automated semi-quantitative toxicological screening in three biological matrices using turbulent flow chromatography/high resolution mass spectrometry.

Roche L, Pinguet J, Herviou P, Libert F, Chenaf C, Eschalier A, Authier N, Richard D.

Clin Chim Acta. 2016 Apr 1;455:46-54. doi: 10.1016/j.cca.2016.01.017. Epub 2016 Jan 23.


Determination of irinotecan and SN38 in human plasma by TurboFlow™ liquid chromatography-tandem mass spectrometry.

Herviou P, Richard D, Roche L, Pinguet J, Libert F, Eschalier A, Durando X, Authier N.

J Pharm Biomed Anal. 2016 Jan 25;118:284-291. doi: 10.1016/j.jpba.2015.10.044. Epub 2015 Nov 4.


Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.

Fumagalli D, Gacquer D, Rothé F, Lefort A, Libert F, Brown D, Kheddoumi N, Shlien A, Konopka T, Salgado R, Larsimont D, Polyak K, Willard-Gallo K, Desmedt C, Piccart M, Abramowicz M, Campbell PJ, Sotiriou C, Detours V.

Cell Rep. 2015 Oct 13;13(2):277-89. doi: 10.1016/j.celrep.2015.09.032. Epub 2015 Oct 1.


[Therapeutic Drug Monitoring of Clozapine].

Djerada Z, Daviet F, Llorca PM, Eschalier A, Saint-Marcoux F, Bentué-Ferrer D, Libert F.

Therapie. 2015 Jul 28. [Epub ahead of print] French.


[Therapeutic Drug Monitoring of Olanzapine].

Djerada Z, Brousse G, Niel P, Llorca PM, Eschalier A, Bentue-Ferrer D, Libert F.

Therapie. 2015 Jul 28. [Epub ahead of print] French.


[Spondylodiscitis in children: a review. A propos of two cases].

Gueulette E, Sana G, Libert F, Nisolle JF, Bodart E, Tuerlinckx D.

Rev Med Liege. 2015 Apr;70(4):189-94. Review. French.


microRNA expression in autonomous thyroid adenomas: Correlation with mRNA regulation.

Floor SL, Trésallet C, Hébrant A, Desbuleux A, Libert F, Hoang C, Capello M, Andry G, van Staveren WC, Maenhaut C.

Mol Cell Endocrinol. 2015 Aug 15;411:1-10. doi: 10.1016/j.mce.2015.04.001. Epub 2015 Apr 23.


Prevention of oxaliplatin-induced peripheral neuropathy by a polyamine-reduced diet-NEUROXAPOL: protocol of a prospective, randomised, controlled, single-blind and monocentric trial.

Balayssac D, Ferrier J, Pereira B, Gillet B, Pétorin C, Vein J, Libert F, Eschalier A, Pezet D.

BMJ Open. 2015 Apr 1;5(4):e007479. doi: 10.1136/bmjopen-2014-007479.


MiRNA expression may account for chronic but not for acute regulation of mRNA expression in human thyroid tumor models.

Floor SL, Hebrant A, Pita JM, Saiselet M, Trésallet C, Libert F, Andry G, Dumont JE, van Staveren WC, Maenhaut C.

PLoS One. 2014 Nov 6;9(11):e111581. doi: 10.1371/journal.pone.0111581. eCollection 2014.


Buccal acetaminophen provides fast analgesia: two randomized clinical trials in healthy volunteers.

Pickering G, Macian N, Libert F, Cardot JM, Coissard S, Perovitch P, Maury M, Dubray C.

Drug Des Devel Ther. 2014 Sep 26;8:1621-7. doi: 10.2147/DDDT.S63476. eCollection 2014.


Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium.

Mustata RC, Vasile G, Fernandez-Vallone V, Strollo S, Lefort A, Libert F, Monteyne D, Pérez-Morga D, Vassart G, Garcia MI.

Cell Rep. 2013 Oct 31;5(2):421-32. doi: 10.1016/j.celrep.2013.09.005. Epub 2013 Oct 17.


Fatty acid amide hydrolase-dependent generation of antinociceptive drug metabolites acting on TRPV1 in the brain.

Barrière DA, Mallet C, Blomgren A, Simonsen C, Daulhac L, Libert F, Chapuy E, Etienne M, Högestätt ED, Zygmunt PM, Eschalier A.

PLoS One. 2013 Aug 5;8(8):e70690. doi: 10.1371/journal.pone.0070690. Print 2013.


Hyperosmotic stress induces cell cycle arrest in retinal pigmented epithelial cells.

Arsenijevic T, Vujovic A, Libert F, Op de Beeck A, Hébrant A, Janssens S, Grégoire F, Lefort A, Bolaky N, Perret J, Caspers L, Willermain F, Delporte C.

Cell Death Dis. 2013 Jun 6;4:e662. doi: 10.1038/cddis.2013.189.


5-aza-2'-deoxycytidine has minor effects on differentiation in human thyroid cancer cell lines, but modulates genes that are involved in adaptation in vitro.

Dom G, Galdo VC, Tarabichi M, Tomás G, Hébrant A, Andry G, De Martelar V, Libert F, Leteurtre E, Dumont JE, Maenhaut C, van Staveren WC.

Thyroid. 2013 Mar;23(3):317-28. doi: 10.1089/thy.2012.0388.


Kinetochore KMN network gene CASC5 mutated in primary microcephaly.

Genin A, Desir J, Lambert N, Biervliet M, Van Der Aa N, Pierquin G, Killian A, Tosi M, Urbina M, Lefort A, Libert F, Pirson I, Abramowicz M.

Hum Mol Genet. 2012 Dec 15;21(24):5306-17. doi: 10.1093/hmg/dds386. Epub 2012 Sep 13.


Measurement of imatinib uptake by flow cytometry.

Bourgne C, Bamdad M, Janel A, Libert F, Gagnieu MC, Rapatel C, Pigeon P, Pereira S, Hermet E, Guerci A, Pereira B, Makhoul PC, Ansah AJ, Cahn JY, Guyotat D, Trouillier S, Berger J, Boiret-Dupré N, Berger MG.

Cytometry A. 2012 Nov;81(11):996-1004. doi: 10.1002/cyto.a.22118. Epub 2012 Aug 28.


Functional inactivation of thyroid transcription factor-1 in PCCl3 thyroid cells.

Christophe-Hobertus C, Lefort A, Libert F, Christophe D.

Mol Cell Endocrinol. 2012 Jul 6;358(1):36-45. doi: 10.1016/j.mce.2012.02.013. Epub 2012 Feb 19.


Role of Epac and protein kinase A in thyrotropin-induced gene expression in primary thyrocytes.

van Staveren WC, Beeckman S, Tomás G, Dom G, Hébrant A, Delys L, Vliem MJ, Trésallet C, Andry G, Franc B, Libert F, Dumont JE, Maenhaut C.

Exp Cell Res. 2012 Mar 10;318(5):444-52. doi: 10.1016/j.yexcr.2011.12.022. Epub 2012 Jan 4.


[Level of evidence for therapeutic drug monitoring of itraconazole].

Charles M, Le Guellec C, Richard D, Libert F; Groupe Suivi Therapeutique Pharmacologique de la Societe Francaise de Pharmacologie et de Therapeutique.

Therapie. 2011 Mar-Apr;66(2):103-8. Epub 2011 Jun 6. Review. French.


Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo.

Mustata RC, Van Loy T, Lefort A, Libert F, Strollo S, Vassart G, Garcia MI.

EMBO Rep. 2011 Jun;12(6):558-64. doi: 10.1038/embor.2011.52. Epub 2011 Apr 21.


Vitamin D deficiency-induced hypertension is associated with vascular oxidative stress and altered heart gene expression.

Argacha JF, Egrise D, Pochet S, Fontaine D, Lefort A, Libert F, Goldman S, van de Borne P, Berkenboom G, Moreno-Reyes R.

J Cardiovasc Pharmacol. 2011 Jul;58(1):65-71. doi: 10.1097/FJC.0b013e31821c832f.


Genes expressed in specific areas of the human fetal cerebral cortex display distinct patterns of evolution.

Lambert N, Lambot MA, Bilheu A, Albert V, Englert Y, Libert F, Noel JC, Sotiriou C, Holloway AK, Pollard KS, Detours V, Vanderhaeghen P.

PLoS One. 2011 Mar 18;6(3):e17753. doi: 10.1371/journal.pone.0017753.


Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?

Wattiez AS, Libert F, Privat AM, Loiodice S, Fialip J, Eschalier A, Courteix C.

Br J Pharmacol. 2011 Jun;163(4):792-803. doi: 10.1111/j.1476-5381.2011.01297.x.


Niveau de preuve du suivi thérapeutique pharmacologique de l'itraconazole.

Charles M, Le Guellec C, Richard D, Libert F; pour le groupe Suivi Thérapeutique Pharmacologique de la Société Française de Pharmacologie et de Thérapeutique.

Therapie. 2011 Mar-Apr;66(2):103-8. doi: 10.2515/therapie/2011015. French.


Development of a Bayesian estimator for the therapeutic drug monitoring of mycophenolate mofetil in children with idiopathic nephrotic syndrome.

Saint-Marcoux F, Guigonis V, Decramer S, Gandia P, Ranchin B, Parant F, Bessenay L, Libert F, Harambat J, Bouchet S, Broux F, Compagnon P, Marquet P.

Pharmacol Res. 2011 May;63(5):423-31. doi: 10.1016/j.phrs.2011.01.009. Epub 2011 Jan 25.


Transcriptome, methylome and genomic variations analysis of ectopic thyroid glands.

Abu-Khudir R, Paquette J, Lefort A, Libert F, Chanoine JP, Vassart G, Deladoëy J.

PLoS One. 2010 Oct 15;5(10):e13420. doi: 10.1371/journal.pone.0013420.


Kit K641E oncogene up-regulates Sprouty homolog 4 and trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours.

Gromova P, Ralea S, Lefort A, Libert F, Rubin BP, Erneux C, Vanderwinden JM.

J Cell Mol Med. 2009 Aug;13(8A):1536-48. doi: 10.1111/j.1582-4934.2009.00768.x. Epub 2009 May 19.


LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine.

Garcia MI, Ghiani M, Lefort A, Libert F, Strollo S, Vassart G.

Dev Biol. 2009 Jul 1;331(1):58-67. doi: 10.1016/j.ydbio.2009.04.020. Epub 2009 Apr 24.


Genotypic and gene expression studies in congenital melanocytic nevi: insight into initial steps of melanotumorigenesis.

Dessars B, De Raeve LE, Morandini R, Lefort A, El Housni H, Ghanem GE, Van den Eynde BJ, Ma W, Roseeuw D, Vassart G, Libert F, Heimann P.

J Invest Dermatol. 2009 Jan;129(1):139-47. doi: 10.1038/jid.2008.203. Epub 2008 Jul 17.


Endocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesia.

Mallet C, Daulhac L, Bonnefont J, Ledent C, Etienne M, Chapuy E, Libert F, Eschalier A.

Pain. 2008 Sep 30;139(1):190-200. doi: 10.1016/j.pain.2008.03.030. Epub 2008 May 15.


Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A(2B) receptor.

Ben Addi A, Lefort A, Hua X, Libert F, Communi D, Ledent C, Macours P, Tilley SL, Boeynaems JM, Robaye B.

Eur J Immunol. 2008 Jun;38(6):1610-20. doi: 10.1002/eji.200737781.


Human thyroid tumor cell lines derived from different tumor types present a common dedifferentiated phenotype.

van Staveren WC, Solís DW, Delys L, Duprez L, Andry G, Franc B, Thomas G, Libert F, Dumont JE, Detours V, Maenhaut C.

Cancer Res. 2007 Sep 1;67(17):8113-20.


Gene expression profiling defines ATP as a key regulator of human dendritic cell functions.

Bles N, Horckmans M, Lefort A, Libert F, Macours P, El Housni H, Marteau F, Boeynaems JM, Communi D.

J Immunol. 2007 Sep 15;179(6):3550-8.


Genome-wide gene expression profiling suggests distinct radiation susceptibilities in sporadic and post-Chernobyl papillary thyroid cancers.

Detours V, Delys L, Libert F, Weiss Solís D, Bogdanova T, Dumont JE, Franc B, Thomas G, Maenhaut C.

Br J Cancer. 2007 Sep 17;97(6):818-25. Epub 2007 Aug 21.


Long-term EGF/serum-treated human thyrocytes mimic papillary thyroid carcinomas with regard to gene expression.

Hébrant A, van Staveren WC, Delys L, Solís DW, Bogdanova T, Andry G, Roger P, Dumont JE, Libert F, Maenhaut C.

Exp Cell Res. 2007 Sep 10;313(15):3276-84. Epub 2007 Jul 4. Erratum in: Exp Cell Res. 2007 Nov 15;313(19):4082.


Gene expression and the biological phenotype of papillary thyroid carcinomas.

Delys L, Detours V, Franc B, Thomas G, Bogdanova T, Tronko M, Libert F, Dumont JE, Maenhaut C.

Oncogene. 2007 Dec 13;26(57):7894-903. Epub 2007 Jul 9.


Extracellular nucleotides induce COX-2 up-regulation and prostaglandin E2 production in human A549 alveolar type II epithelial cells.

Marcet B, Libert F, Boeynaems JM, Communi D.

Eur J Pharmacol. 2007 Jul 2;566(1-3):167-71. Epub 2007 Apr 14.


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