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Items: 1 to 50 of 77

1.

Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis.

Sishc BJ, Nelson CB, McKenna MJ, Battaglia CL, Herndon A, Idate R, Liber HL, Bailey SM.

Front Oncol. 2015 Nov 24;5:257. doi: 10.3389/fonc.2015.00257. eCollection 2015.

2.

Radiation quality and mutagenesis in human lymphoblastoid cells.

Liber HL, Idate R, Warner C, Bailey SM.

Radiat Res. 2014 Oct;182(4):390-5. doi: 10.1667/RR13817.1. Epub 2014 Sep 3.

PMID:
25184374
3.

Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.

Dregalla RC, Zhou J, Idate RR, Battaglia CL, Liber HL, Bailey SM.

Aging (Albany NY). 2010 Oct;2(10):691-708.

4.

Distinct signaling pathways after higher or lower doses of radiation in three closely related human lymphoblast cell lines.

Lu TP, Lai LC, Lin BI, Chen LH, Hsiao TH, Liber HL, Cook JA, Mitchell JB, Tsai MH, Chuang EY.

Int J Radiat Oncol Biol Phys. 2010 Jan 1;76(1):212-9. doi: 10.1016/j.ijrobp.2009.08.015.

PMID:
20005454
5.

Ionizing radiation-induced bystander mutagenesis and adaptation: quantitative and temporal aspects.

Zhang Y, Zhou J, Baldwin J, Held KD, Prise KM, Redmond RW, Liber HL.

Mutat Res. 2009 Dec 1;671(1-2):20-5. doi: 10.1016/j.mrfmmm.2009.08.006. Epub 2009 Aug 18.

6.

Bystander effects induced by diffusing mediators after photodynamic stress.

Chakraborty A, Held KD, Prise KM, Liber HL, Redmond RW.

Radiat Res. 2009 Jul;172(1):74-81. doi: 10.1667/RR1669.1.

7.

Real-time imaging of novel spatial and temporal responses to photodynamic stress.

Rubio N, Rajadurai A, Held KD, Prise KM, Liber HL, Redmond RW.

Free Radic Biol Med. 2009 Aug 1;47(3):283-90. doi: 10.1016/j.freeradbiomed.2009.04.024. Epub 2009 May 3.

PMID:
19409981
8.

Deficiencies of double-strand break repair factors and effects on mutagenesis in directly gamma-irradiated and medium-mediated bystander human lymphoblastoid cells.

Zhang Y, Zhou J, Held KD, Redmond RW, Prise KM, Liber HL.

Radiat Res. 2008 Feb;169(2):197-206. doi: 10.1667/RR1189.1.

PMID:
18220473
9.

Wild-type p53 reduces radiation hypermutability in p53-mutated human lymphoblast cells.

Zhang Q, Liu Y, Zhou J, Chen W, Zhang Y, Liber HL.

Mutagenesis. 2007 Sep;22(5):329-34. Epub 2007 Jun 13.

PMID:
17567629
10.

Induction and loss of a TP53-dependent radioadaptive response in the human lymphoblastoid cell model TK6 and its abrogation by BCL2 over-expression.

Schwartz JL, Jordan R, Slovic J, Moruzzi AM, Kimmel RR, Liber HL.

Int J Radiat Biol. 2007 Mar;83(3):153-9.

PMID:
17378523
11.

Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells.

Zhang Y, Zhou J, Cao X, Zhang Q, Lim CU, Ullrich RL, Bailey SM, Liber HL.

Cancer Lett. 2007 May 18;250(1):63-73. Epub 2006 Nov 13.

PMID:
17095151
12.

Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells.

Tsai MH, Chen X, Chandramouli GV, Chen Y, Yan H, Zhao S, Keng P, Liber HL, Coleman CN, Mitchell JB, Chuang EY.

Oncogene. 2006 Jan 26;25(4):622-32.

PMID:
16247478
13.

Suppression of DNA-PK by RNAi has different quantitative effects on telomere dysfunction and mutagenesis in human lymphoblasts treated with gamma rays or HZE particles.

Zhang Q, Williams ES, Askin KF, Peng Y, Bedford JS, Liber HL, Bailey SM.

Radiat Res. 2005 Oct;164(4 Pt 2):497-504.

PMID:
16187756
14.

NBS1 knockdown by small interfering RNA increases ionizing radiation mutagenesis and telomere association in human cells.

Zhang Y, Lim CU, Williams ES, Zhou J, Zhang Q, Fox MH, Bailey SM, Liber HL.

Cancer Res. 2005 Jul 1;65(13):5544-53.

15.

Baseline levels of chromosome instability in the human lymphoblastoid cell TK6.

Schwartz JL, Jordan R, Evans HH, Lenarczyk M, Liber HL.

Mutagenesis. 2004 Nov;19(6):477-82.

PMID:
15548760
16.
19.

Radiation-induced mutations at the autosomal thymidine kinase locus are not elevated in p53-null cells.

Chuang YY, Chen Q, Brown JP, Sedivy JM, Liber HL.

Cancer Res. 1999 Jul 1;59(13):3073-6. Erratum in: Cancer Res 1999 Oct 15;59(20):5400.

20.

Interrelationships between radiation-induced mutations and modifications in gene expression linked to cancer.

Liber HL, Phillips EN.

Crit Rev Eukaryot Gene Expr. 1998;8(3-4):257-76. Review.

PMID:
9807696
21.
23.
25.

Mutant frequency at the hprt locus in human lymphocytes in a case-control study of lung cancer.

Cheng TJ, Christiani DC, Liber HL, Wain JC, Xu X, Wiencke JK, Kelsey KT.

Mutat Res. 1995 Nov;332(1-2):109-18.

PMID:
7500985
26.
27.

Electroporation of human lymphoblastoid cells.

Xia F, Liber HL.

Methods Mol Biol. 1995;48:151-60. No abstract available.

PMID:
8528388
28.
29.
30.

Genotoxicity to human cells induced by air particulates isolated during the Kuwait oil fires.

Kelsey KT, Xia F, Bodell WJ, Spengler JD, Christiani DC, Dockery DW, Liber HL.

Environ Res. 1994 Jan;64(1):18-25.

PMID:
8287839
31.

Mutational spectrum of ICR-191 at the hprt locus in human lymphoblastoid cells.

Taft SA, Liber HL, Skopek TR.

Environ Mol Mutagen. 1994;23(2):96-100.

PMID:
8143707
33.

Mutagenesis after cancer therapy.

Kelsey KT, Caggana M, Mauch PM, Coleman CN, Clark JR, Liber HL.

Environ Health Perspect. 1993 Oct;101 Suppl 3:177-84.

35.

Mutagenesis after therapy for Hodgkin's disease.

Kelsey KT, Caggana-Aviles M, Mauch P, Coleman CN, Shulman LN, Liber HL.

Hematol Oncol Clin North Am. 1993 Apr;7(2):353-67.

PMID:
8468270
36.
37.

Heritable alterations at the adenine phosphoribosyltransferase (APRT) locus in human lymphoblastoid cell lines.

Amundson SA, Fortunato JE, Liber HL.

Mutat Res. 1992 Dec 16;284(2):287-95.

PMID:
1281280
38.

Induction of mutations by bismuth-212 alpha particles at two genetic loci in human B-lymphoblasts.

Metting NF, Palayoor ST, Macklis RM, Atcher RW, Liber HL, Little JB.

Radiat Res. 1992 Dec;132(3):339-45.

PMID:
1475356
39.

A prospective study of hprt mutant and mutation frequencies in treated cancer patients.

Caggana M, Liber HL, Coleman CN, Mauch P, Clark JR, Kelsey KT.

Cancer Epidemiol Biomarkers Prev. 1992 Nov-Dec;1(7):573-80.

40.
41.

In vivo exposure of human lymphocytes to technetium-99m in nuclear medicine patients does not induce detectable genetic effects.

Kelsey KT, Donohoe KJ, Memisoglu A, Baxter B, Caggana M, Liber HL.

Mutat Res. 1991 Dec;264(4):213-8.

PMID:
1723502
42.
43.

Mutagenicity of 2-amino-N6-hydroxyadenine to TK6 human lymphoblast cells.

Liber HL, Denault CM.

Mutat Res. 1991 Aug;253(1):91-5.

PMID:
1870612
44.

Human lymphocytes exposed to low doses of X-rays are less susceptible to radiation-induced mutagenesis.

Kelsey KT, Memisoglu A, Frenkel D, Liber HL.

Mutat Res. 1991 Aug;263(4):197-201.

PMID:
1861683
45.

RFLP mapping of thymidine kinase mutants places D17S4 proximal to the human TK1 locus.

Amundson SA, Benjamin MB, Little JB, Liber HL.

Nucleic Acids Res. 1991 Jul 11;19(13):3748. No abstract available.

46.

Genotoxic and mutagenic effects of the diagnostic use of thallium-201 in nuclear medicine.

Kelsey KT, Donohoe KJ, Baxter B, Memisoglu A, Little JB, Caggana M, Liber HL.

Mutat Res. 1991 Jul;260(3):239-46.

PMID:
1870614
47.

A comparison of induced mutation at homologous alleles of the tk locus in human cells.

Amundson SA, Liber HL.

Mutat Res. 1991 Mar;247(1):19-27.

PMID:
1672226
48.

In vivo somatic mutation in the lymphocytes of Hodgkin's disease patients.

Caggana M, Liber HL, Mauch PM, Coleman CN, Kelsey KT.

Environ Mol Mutagen. 1991;18(1):6-13.

PMID:
1713845
49.
50.

Formaldehyde-induced and spontaneous alterations in human hprt DNA sequence and mRNA expression.

Liber HL, Benforado K, Crosby RM, Simpson D, Skopek TR.

Mutat Res. 1989 May;226(1):31-7.

PMID:
2716766

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