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Items: 1 to 50 of 773

1.

Antibody-based immunotherapy targeting cytokines and atherothrombotic cardiovascular diseases: A review for future perspectives.

Ait-Oufella H, Libby P, Tedgui A.

Arch Cardiovasc Dis. 2020 Jan 5. pii: S1875-2136(19)30225-6. doi: 10.1016/j.acvd.2019.11.001. [Epub ahead of print] No abstract available.

PMID:
31917124
2.

Effects of Interleukin-1β Inhibition on Blood Pressure, Incident Hypertension, and Residual Inflammatory Risk: A Secondary Analysis of CANTOS.

Rothman AM, MacFadyen J, Thuren T, Webb A, Harrison DG, Guzik TJ, Libby P, Glynn RJ, Ridker PM.

Hypertension. 2020 Feb;75(2):477-482. doi: 10.1161/HYPERTENSIONAHA.119.13642. Epub 2019 Dec 30.

PMID:
31884854
3.

The Myocardium: More Than Myocytes.

Libby P, Swirski FK, Nahrendorf M.

J Am Coll Cardiol. 2019 Dec 24;74(25):3136-3138. doi: 10.1016/j.jacc.2019.10.031. No abstract available.

PMID:
31856970
4.

Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects.

Rogers MA, Chen J, Nallamshetty S, Pham T, Goto S, Muehlschlegel JD, Libby P, Aikawa M, Aikawa E, Plutzky J.

Arterioscler Thromb Vasc Biol. 2019 Dec 19:ATVBAHA119313366. doi: 10.1161/ATVBAHA.119.313366. [Epub ahead of print]

PMID:
31852220
5.

Adipocytes promote interleukin-18 binding to its receptors during abdominal aortic aneurysm formation in mice.

Liu CL, Ren J, Wang Y, Zhang X, Sukhova GK, Liao M, Santos M, Luo S, Yang D, Xia M, Inouye K, Hotamisligil GS, Lu G, Upchurch GR, Libby P, Guo J, Zhang J, Shi GP.

Eur Heart J. 2019 Dec 10. pii: ehz856. doi: 10.1093/eurheartj/ehz856. [Epub ahead of print]

PMID:
31821481
6.

Linking regulation of nitric oxide to endothelin-1: The Yin and Yang of vascular tone in the atherosclerotic plaque.

Gupta RM, Libby P, Barton M.

Atherosclerosis. 2020 Jan;292:201-203. doi: 10.1016/j.atherosclerosis.2019.11.001. Epub 2019 Nov 14. No abstract available.

PMID:
31810569
7.

Interleukin-1β Mediates Arterial Thrombus Formation via NET-Associated Tissue Factor.

Liberale L, Holy EW, Akhmedov A, Bonetti NR, Nietlispach F, Matter CM, Mach F, Montecucco F, Beer JH, Paneni F, Ruschitzka F, Libby P, Lüscher TF, Camici GG.

J Clin Med. 2019 Nov 26;8(12). pii: E2072. doi: 10.3390/jcm8122072.

8.

Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge.

Hoyer FF, Naxerova K, Schloss MJ, Hulsmans M, Nair AV, Dutta P, Calcagno DM, Herisson F, Anzai A, Sun Y, Wojtkiewicz G, Rohde D, Frodermann V, Vandoorne K, Courties G, Iwamoto Y, Garris CS, Williams DL, Breton S, Brown D, Whalen M, Libby P, Pittet MJ, King KR, Weissleder R, Swirski FK, Nahrendorf M.

Immunity. 2019 Nov 19;51(5):899-914.e7. doi: 10.1016/j.immuni.2019.10.010. Epub 2019 Nov 12.

PMID:
31732166
9.

Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis.

Bick AG, Pirruccello JP, Griffin GK, Gupta N, Gabriel S, Saleheen D, Libby P, Kathiresan S, Natarajan P.

Circulation. 2020 Jan 14;141(2):124-131. doi: 10.1161/CIRCULATIONAHA.119.044362. Epub 2019 Nov 11.

PMID:
31707836
10.

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells.

Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, Grune J, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Lee IH, Gustafsson K, Pasterkamp G, de Jager SCA, Sadreyev RI, MacFadyen J, Libby P, Ridker P, Scadden DT, Naxerova K, Jeffrey KL, Swirski FK, Nahrendorf M.

Nat Med. 2019 Nov;25(11):1761-1771. doi: 10.1038/s41591-019-0633-x. Epub 2019 Nov 7.

PMID:
31700184
11.

A new opening on aortic stenosis: predicting prognosis with clonal haematopoiesis.

Lin AE, Libby P, Ebert BL.

Eur Heart J. 2019 Oct 21. pii: ehz752. doi: 10.1093/eurheartj/ehz752. [Epub ahead of print] No abstract available.

PMID:
31634387
12.

From Focal Lipid Storage to Systemic Inflammation: JACC Review Topic of the Week.

Libby P, Hansson GK.

J Am Coll Cardiol. 2019 Sep 24;74(12):1594-1607. doi: 10.1016/j.jacc.2019.07.061. Review.

PMID:
31537270
14.

Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis.

Liu CL, Zhang X, Liu J, Wang Y, Sukhova GK, Wojtkiewicz GR, Liu T, Tang R, Achilefu S, Nahrendorf M, Libby P, Guo J, Zhang JY, Shi GP.

Nat Commun. 2019 Sep 4;10(1):3978. doi: 10.1038/s41467-019-11983-3.

15.

Fluorodeoxyglucose Uptake in Atheroma: Not So Simple.

Libby P, Bhatt DL, Di Carli M.

J Am Coll Cardiol. 2019 Sep 3;74(9):1233-1236. doi: 10.1016/j.jacc.2019.07.009. No abstract available.

PMID:
31466621
16.

Differential Roles of Cysteinyl Cathepsins in TGF-β Signaling and Tissue Fibrosis.

Zhang X, Zhou Y, Yu X, Huang Q, Fang W, Li J, Bonventre JV, Sukhova GK, Libby P, Shi GP.

iScience. 2019 Sep 27;19:607-622. doi: 10.1016/j.isci.2019.08.014. Epub 2019 Aug 9.

17.

Atherosclerosis.

Libby P, Buring JE, Badimon L, Hansson GK, Deanfield J, Bittencourt MS, Tokgözoğlu L, Lewis EF.

Nat Rev Dis Primers. 2019 Aug 16;5(1):56. doi: 10.1038/s41572-019-0106-z. Review.

PMID:
31420554
18.

Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease.

Jaiswal S, Libby P.

Nat Rev Cardiol. 2019 Aug 12. doi: 10.1038/s41569-019-0247-5. [Epub ahead of print] Review.

PMID:
31406340
19.

Residual vascular risk in diabetes - Will the SPPARM alpha concept hold the key?

Fruchart JC, Santos RD, Yamashita S, Libby P; International Atherosclerosis Society/R3i Foundation Consensus Panel.

Diabetes Metab Syndr. 2019 Jul - Aug;13(4):2723-2725. doi: 10.1016/j.dsx.2019.05.034. Epub 2019 May 30. Review. No abstract available.

PMID:
31405699
20.

Inhibiting NLRP3 Inflammasome Activity in Acute Myocardial Infarction: A Review of Pharmacologic Agents and Clinical Outcomes.

Buckley LF, Libby P.

J Cardiovasc Pharmacol. 2019 Oct;74(4):297-305. doi: 10.1097/FJC.0000000000000701.

PMID:
31356538
21.

Clonal Hematopoiesis: Crossroads of Aging, Cardiovascular Disease, and Cancer: JACC Review Topic of the Week.

Libby P, Sidlow R, Lin AE, Gupta D, Jones LW, Moslehi J, Zeiher A, Jaiswal S, Schulz C, Blankstein R, Bolton KL, Steensma D, Levine RL, Ebert BL.

J Am Coll Cardiol. 2019 Jul 30;74(4):567-577. doi: 10.1016/j.jacc.2019.06.007. Review.

PMID:
31345432
22.

Anticytokine Immune Therapy and Atherothrombotic Cardiovascular Risk.

Ait-Oufella H, Libby P, Tedgui A.

Arterioscler Thromb Vasc Biol. 2019 Aug;39(8):1510-1519. doi: 10.1161/ATVBAHA.119.311998. Epub 2019 Jul 11.

PMID:
31294625
23.

Low-Density Lipoprotein Cholesterol After an Acute Coronary Syndrome: How Low to Go?

Qamar A, Libby P.

Curr Cardiol Rep. 2019 Jun 27;21(8):77. doi: 10.1007/s11886-019-1160-6. Review.

PMID:
31250329
24.

Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology.

Ketelhuth DFJ, Lutgens E, Bäck M, Binder CJ, Van den Bossche J, Daniel C, Dumitriu IE, Hoefer I, Libby P, O'Neill L, Weber C, Evans PC.

Cardiovasc Res. 2019 Jul 1;115(9):1385-1392. doi: 10.1093/cvr/cvz166.

PMID:
31228191
25.

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation.

Fruchart JC, Santos RD, Aguilar-Salinas C, Aikawa M, Al Rasadi K, Amarenco P, Barter PJ, Ceska R, Corsini A, Després JP, Duriez P, Eckel RH, Ezhov MV, Farnier M, Ginsberg HN, Hermans MP, Ishibashi S, Karpe F, Kodama T, Koenig W, Krempf M, Lim S, Lorenzatti AJ, McPherson R, Nuñez-Cortes JM, Nordestgaard BG, Ogawa H, Packard CJ, Plutzky J, Ponte-Negretti CI, Pradhan A, Ray KK, Reiner Ž, Ridker PM, Ruscica M, Sadikot S, Shimano H, Sritara P, Stock JK, Su TC, Susekov AV, Tartar A, Taskinen MR, Tenenbaum A, Tokgözoğlu LS, Tomlinson B, Tybjærg-Hansen A, Valensi P, Vrablík M, Wahli W, Watts GF, Yamashita S, Yokote K, Zambon A, Libby P.

Cardiovasc Diabetol. 2019 Jun 4;18(1):71. doi: 10.1186/s12933-019-0864-7. Review.

26.

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.

Shikatani EA, Besla R, Ensan S, Upadhye A, Khyzha N, Li A, Emoto T, Chiu F, Degousee N, Moreau JM, Perry HM, Thayaparan D, Cheng HS, Pacheco S, Smyth D, Noyan H, Zavitz CCJ, Bauer CMT, Hilgendorf I, Libby P, Swirski FK, Gommerman JL, Fish JE, Stampfli MR, Cybulsky MI, Rubin BB, Paige CJ, Bender TP, McNamara CA, Husain M, Robbins CS.

Cell Rep. 2019 May 21;27(8):2304-2312.e6. doi: 10.1016/j.celrep.2019.04.090.

27.

Targeting RNA to lower triglycerides: long strides from short molecules.

Qamar A, Libby P, Bhatt DL.

Eur Heart J. 2019 Sep 1;40(33):2797-2800. doi: 10.1093/eurheartj/ehz321. No abstract available.

28.

Leaders in Cardiovascular Research: Peter Libby.

Guzik TJ, Libby P.

Cardiovasc Res. 2019 May 1;115(6):e61-e62. doi: 10.1093/cvr/cvz069. No abstract available.

PMID:
31077586
29.

Johann Sebastian Bach.

Libby P.

Circ Res. 2019 Apr 26;124(9):1303-1308. doi: 10.1161/CIRCRESAHA.119.315025. No abstract available.

PMID:
31021721
30.

Dietary cholesterol is essential to mast cell activation and associated obesity and diabetes in mice.

Zhang X, Huang Q, Wang X, Deng Z, Li J, Yan X, Jauhiainen M, Metso J, Libby P, Liu J, Shi GP.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1690-1700. doi: 10.1016/j.bbadis.2019.04.006. Epub 2019 Apr 9.

PMID:
30978390
31.

Modulating Adaptive Immunity in Vascular Disease: CD4 to the Fore.

Libby P, Lichtman AI.

J Am Coll Cardiol. 2019 Apr 16;73(14):1824-1826. doi: 10.1016/j.jacc.2019.01.050. No abstract available.

PMID:
30975300
32.

Editorial commentary: Arson in the artery: Who set the atheroma aflame?

Libby P.

Trends Cardiovasc Med. 2019 Nov;29(8):473-475. doi: 10.1016/j.tcm.2019.03.006. Epub 2019 Mar 28.

PMID:
30956033
33.

Arterial Inflammation: The Heat Before the Storm.

Blankstein R, Libby P, Bhatt DL.

J Am Coll Cardiol. 2019 Apr 2;73(12):1383-1385. doi: 10.1016/j.jacc.2019.02.002. No abstract available.

PMID:
30922469
34.

Inflammation: a common contributor to cancer, aging, and cardiovascular diseases-expanding the concept of cardio-oncology.

Libby P, Kobold S.

Cardiovasc Res. 2019 Apr 15;115(5):824-829. doi: 10.1093/cvr/cvz058.

PMID:
30830168
35.

Novel Antiatherosclerotic Therapies.

Libby P, Everett BM.

Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):538-545. doi: 10.1161/ATVBAHA.118.310958. Review.

PMID:
30816799
36.

Once more unto the breach: endothelial permeability and atherogenesis.

Libby P.

Eur Heart J. 2019 Mar 14;40(11):938-940. doi: 10.1093/eurheartj/ehz081.

PMID:
30805590
37.

Dysregulation of IL-33/ST2 signaling and myocardial periarteriolar fibrosis.

Garbern JC, Williams J, Kristl AC, Malick A, Rachmin I, Gaeta B, Ahmed N, Vujic A, Libby P, Lee RT.

J Mol Cell Cardiol. 2019 Mar;128:179-186. doi: 10.1016/j.yjmcc.2019.01.018. Epub 2019 Feb 11.

PMID:
30763587
38.

Sleep modulates haematopoiesis and protects against atherosclerosis.

McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK.

Nature. 2019 Feb;566(7744):383-387. doi: 10.1038/s41586-019-0948-2. Epub 2019 Feb 13.

39.

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.

He S, Kahles F, Rattik S, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK.

Nature. 2019 Feb;566(7742):115-119. doi: 10.1038/s41586-018-0849-9. Epub 2019 Jan 30.

40.

Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis.

Vromman A, Ruvkun V, Shvartz E, Wojtkiewicz G, Santos Masson G, Tesmenitsky Y, Folco E, Gram H, Nahrendorf M, Swirski FK, Sukhova GK, Libby P.

Eur Heart J. 2019 Aug 7;40(30):2482-2491. doi: 10.1093/eurheartj/ehz008.

PMID:
30698710
41.

Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis.

Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK.

J Exp Med. 2019 Feb 4;216(2):369-383. doi: 10.1084/jem.20180722. Epub 2019 Jan 22.

42.

Deficiency of mouse mast cell protease 4 mitigates cardiac dysfunctions in mice after myocardium infarction.

Wang Y, Liu CL, Fang W, Zhang X, Yang C, Li J, Liu J, Sukhova GK, Gurish MF, Libby P, Shi GP, Zhang J.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1170-1181. doi: 10.1016/j.bbadis.2019.01.011. Epub 2019 Jan 11.

PMID:
30639224
43.

Cardiovascular Benefits of GLP-1 Receptor Agonism: Is Inflammation a Key?

Marx N, Libby P.

JACC Basic Transl Sci. 2018 Dec 31;3(6):858-860. doi: 10.1016/j.jacbts.2018.11.008. eCollection 2018 Dec. No abstract available.

44.

Nanoparticles targeting extra domain B of fibronectin-specific to the atherosclerotic lesion types III, IV, and V-enhance plaque detection and cargo delivery.

Yu M, Ortega CA, Si K, Molinaro R, Schoen FJ, Leitao RFC, Xu X, Mahmoudi M, Ahn S, Liu J, Saw PE, Lee IH, Brayner MMB, Lotfi A, Shi J, Libby P, Jon S, Farokhzad OC.

Theranostics. 2018 Nov 15;8(21):6008-6024. doi: 10.7150/thno.24365. eCollection 2018.

45.

Reassessing the Mechanisms of Acute Coronary Syndromes.

Libby P, Pasterkamp G, Crea F, Jang IK.

Circ Res. 2019 Jan 4;124(1):150-160. doi: 10.1161/CIRCRESAHA.118.311098. Review.

46.

Anti-Inflammatory Therapy With Canakinumab for the Prevention of Hospitalization for Heart Failure.

Everett BM, Cornel JH, Lainscak M, Anker SD, Abbate A, Thuren T, Libby P, Glynn RJ, Ridker PM.

Circulation. 2019 Mar 5;139(10):1289-1299. doi: 10.1161/CIRCULATIONAHA.118.038010.

PMID:
30586730
47.

Jak-ing Up the Plaque's Lipid Core…and Even More.

Libby P, Molinaro R, Sellar RS, Ebert BL.

Circ Res. 2018 Nov 9;123(11):1180-1182. doi: 10.1161/CIRCRESAHA.118.314074. No abstract available.

48.

Fish Oil and Perioperative Bleeding.

Akintoye E, Sethi P, Harris WS, Thompson PA, Marchioli R, Tavazzi L, Latini R, Pretorius M, Brown NJ, Libby P, Mozaffarian D.

Circ Cardiovasc Qual Outcomes. 2018 Nov;11(11):e004584. doi: 10.1161/CIRCOUTCOMES.118.004584.

49.

CHIPping Away at the Pathogenesis of Heart Failure.

Libby P, Jaiswal S, Lin AE, Ebert BL.

JAMA Cardiol. 2019 Jan 1;4(1):5-6. doi: 10.1001/jamacardio.2018.4039. No abstract available.

PMID:
30566187
50.

Medical Therapy for Long-Term Prevention of Atherothrombosis Following an Acute Coronary Syndrome: JACC State-of-the-Art Review.

Gallone G, Baldetti L, Pagnesi M, Latib A, Colombo A, Libby P, Giannini F.

J Am Coll Cardiol. 2018 Dec 11;72(23 Pt A):2886-2903. doi: 10.1016/j.jacc.2018.09.052. Review.

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