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Items: 1 to 50 of 268

1.

Serine-threonine kinase, ROCK2, regulates germinal center B cell positioning and cholesterol biosynthesis.

Ricker E, Chinenov Y, Pannellini T, Flores Castro DM, Ye C, Gupta S, Manni M, Liao JK, Pernis A.

J Clin Invest. 2020 Mar 31. pii: 132414. doi: 10.1172/JCI132414. [Epub ahead of print]

2.

Community Health Workers Reduce Rehospitalizations and Emergency Department Visits for Low-Socioeconomic Urban Patients with Heart Failure.

Vohra AS, Chua RFM, Besser SA, Alcain CF, Basnet S, Battle B, Coplan MJ, Liao JK, Tabit CE.

Crit Pathw Cardiol. 2020 Mar 11. doi: 10.1097/HPC.0000000000000220. [Epub ahead of print]

PMID:
32209825
3.

Comprehensive treatment of massive macroglossia due to venous and lymphatic malformations.

Chen WL, Liao JK, Zhou B, Chen R, Yuan KF.

Int J Oral Maxillofac Surg. 2020 Jan 20. pii: S0901-5027(20)30005-9. doi: 10.1016/j.ijom.2020.01.005. [Epub ahead of print]

PMID:
31974007
4.

Targeting Rho-associated coiled-coil forming protein kinase (ROCK) in cardiovascular fibrosis and stiffening.

Yu B, Sladojevic N, Blair JE, Liao JK.

Expert Opin Ther Targets. 2020 Jan;24(1):47-62. doi: 10.1080/14728222.2020.1712593. Epub 2020 Jan 9.

PMID:
31906742
5.

A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.

McKerracher L, Shenkar R, Abbinanti M, Cao Y, Peiper A, Liao JK, Lightle R, Moore T, Hobson N, Gallione C, Ruschel J, Koskimäki J, Girard R, Rosen K, Marchuk DA, Awad IA.

Transl Stroke Res. 2019 Aug 24. doi: 10.1007/s12975-019-00725-8. [Epub ahead of print]

PMID:
31446620
6.

Association of Rising Violent Crime With Blood Pressure and Cardiovascular Risk: Longitudinal Evidence From Chicago, 2014-2016.

Tung EL, Chua RFM, Besser SA, Lindau ST, Kolak M, Anyanwu EC, Liao JK, Tabit CE.

Am J Hypertens. 2019 Nov 15;32(12):1192-1198. doi: 10.1093/ajh/hpz134.

PMID:
31414132
7.
8.

Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.

Shenkar R, Peiper A, Pardo H, Moore T, Lightle R, Girard R, Hobson N, Polster SP, Koskimäki J, Zhang D, Lyne SB, Cao Y, Chaudagar K, Saadat L, Gallione C, Pytel P, Liao JK, Marchuk D, Awad IA.

Stroke. 2019 Mar;50(3):738-744. doi: 10.1161/STROKEAHA.118.024058.

9.

Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial.

Polster SP, Stadnik A, Akers AL, Cao Y, Christoforidis GA, Fam MD, Flemming KD, Girard R, Hobson N, Koenig JI, Koskimäki J, Lane K, Liao JK, Lee C, Lyne SB, McBee N, Morrison L, Piedad K, Shenkar R, Sorrentino M, Thompson RE, Whitehead KJ, Zeineddine HA, Hanley DF, Awad IA.

Neurosurgery. 2019 Dec 1;85(6):843-853. doi: 10.1093/neuros/nyy539.

PMID:
30476251
10.

Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study.

Kishimoto S, Oki K, Maruhashi T, Kajikawa M, Matsui S, Hashimoto H, Takaeko Y, Kihara Y, Chayama K, Goto C, Aibara Y, Yusoff FM, Nakashima A, Noma K, Liao JK, Higashi Y.

J Hypertens. 2019 May;37(5):1083-1095. doi: 10.1097/HJH.0000000000001989.

11.

The Pleiotropic Effects of Statins - From Coronary Artery Disease and Stroke to Atrial Fibrillation and Ventricular Tachyarrhythmia.

Oesterle A, Liao JK.

Curr Vasc Pharmacol. 2019;17(3):222-232. doi: 10.2174/1570161116666180817155058.

12.

DROIDS 1.20: A GUI-Based Pipeline for GPU-Accelerated Comparative Protein Dynamics.

Babbitt GA, Mortensen JS, Coppola EE, Adams LE, Liao JK.

Biophys J. 2018 Mar 13;114(5):1009-1017. doi: 10.1016/j.bpj.2018.01.020.

13.

Relationship between the genetic polymorphisms of vicR and vicK Streptococcus mutans genes and early childhood caries in two-year-old children.

Zhuang PL, Yu LX, Liao JK, Zhou Y, Lin HC.

BMC Oral Health. 2018 Mar 12;18(1):39. doi: 10.1186/s12903-018-0501-y.

14.

Impaired Cognitive Performance in Endothelial Nitric Oxide Synthase Knockout Mice After Ischemic Stroke: A Pilot Study.

Li S, Wang Y, Jiang Z, Huai Y, Liao JK, Lynch KA, Zafonte R, Wood LJ, Wang QM.

Am J Phys Med Rehabil. 2018 Jul;97(7):492-499. doi: 10.1097/PHM.0000000000000904.

15.

Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice.

Hiroi Y, Noma K, Kim HH, Sladojevic N, Tabit CE, Li Y, Soydan G, Salomone S, Moskowitz MA, Liao JK.

Circ J. 2018 Mar 23;82(4):1195-1204. doi: 10.1253/circj.CJ-17-0732. Epub 2018 Jan 19.

16.

The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.

Knipe RS, Probst CK, Lagares D, Franklin A, Spinney JJ, Brazee PL, Grasberger P, Zhang L, Black KE, Sakai N, Shea BS, Liao JK, Medoff BD, Tager AM.

Am J Respir Cell Mol Biol. 2018 Apr;58(4):471-481. doi: 10.1165/rcmb.2017-0075OC.

17.

Cancer-associated fibroblasts confer cisplatin resistance of tongue cancer via autophagy activation.

Liao JK, Zhou B, Zhuang XM, Zhuang PL, Zhang DM, Chen WL.

Biomed Pharmacother. 2018 Jan;97:1341-1348. doi: 10.1016/j.biopha.2017.11.024. Epub 2017 Nov 14.

PMID:
29156523
18.

ROCK as a therapeutic target for ischemic stroke.

Sladojevic N, Yu B, Liao JK.

Expert Rev Neurother. 2017 Dec;17(12):1167-1177. doi: 10.1080/14737175.2017.1395700. Epub 2017 Oct 30. Review.

19.

Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction.

Shimizu T, Narang N, Chen P, Yu B, Knapp M, Janardanan J, Blair J, Liao JK.

JCI Insight. 2017 Jul 6;2(13). pii: 93187. doi: 10.1172/jci.insight.93187. eCollection 2017 Jul 6.

20.

Tumor necrosis factor-α levels and non-surgical bleeding in continuous-flow left ventricular assist devices.

Tabit CE, Coplan MJ, Chen P, Jeevanandam V, Uriel N, Liao JK.

J Heart Lung Transplant. 2018 Jan;37(1):107-115. doi: 10.1016/j.healun.2017.06.001. Epub 2017 Jun 8.

21.

Allograft Dermal Matrix for Restoration of Facial Contour Deformities.

Chen WL, Huang ZS, Liao JK, Chen R.

Dermatol Surg. 2017 Aug;43(8):1091-1094. doi: 10.1097/DSS.0000000000001155. No abstract available.

PMID:
28498206
22.

Cardiology Consultation in the Emergency Department Reduces Re-hospitalizations for Low-Socioeconomic Patients with Acute Decompensated Heart Failure.

Tabit CE, Coplan MJ, Spencer KT, Alcain CF, Spiegel T, Vohra AS, Adelman D, Liao JK, Sanghani RM.

Am J Med. 2017 Sep;130(9):1112.e17-1112.e31. doi: 10.1016/j.amjmed.2017.03.044. Epub 2017 Apr 27.

23.

Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets.

Sladojevic N, Oh GT, Kim HH, Beaulieu LM, Falet H, Kaminski K, Freedman JE, Liao JK.

Cardiovasc Res. 2017 Sep 1;113(11):1307-1317. doi: 10.1093/cvr/cvx071.

24.

Pleiotropic Effects of Statins on the Cardiovascular System.

Oesterle A, Laufs U, Liao JK.

Circ Res. 2017 Jan 6;120(1):229-243. doi: 10.1161/CIRCRESAHA.116.308537. Review. Erratum in: Circ Res. 2018 Sep 28;123(8):e20.

25.

Role of ROCK2 in CD4+ cells in allergic airways responses in mice.

Kasahara DI, Mathews JA, Ninin FM, Wurmbrand AP, Liao JK, Shore SA.

Clin Exp Allergy. 2017 Feb;47(2):224-235. doi: 10.1111/cea.12866. Epub 2017 Jan 11.

26.

RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.

Shenkar R, Shi C, Austin C, Moore T, Lightle R, Cao Y, Zhang L, Wu M, Zeineddine HA, Girard R, McDonald DA, Rorrer A, Gallione C, Pytel P, Liao JK, Marchuk DA, Awad IA.

Stroke. 2017 Jan;48(1):187-194. doi: 10.1161/STROKEAHA.116.015013. Epub 2016 Nov 22.

27.

MnTBAP increases BMPR-II expression in endothelial cells and attenuates vascular inflammation.

Zhou Q, Einert M, Schmitt H, Wang Z, Pankratz F, Olivier CB, Bode C, Liao JK, Moser M.

Vascul Pharmacol. 2016 Sep;84:67-73. doi: 10.1016/j.vph.2016.07.001. Epub 2016 Jul 8.

28.

Elevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Nonsurgical Bleeding.

Tabit CE, Chen P, Kim GH, Fedson SE, Sayer G, Coplan MJ, Jeevanandam V, Uriel N, Liao JK.

Circulation. 2016 Jul 12;134(2):141-52. doi: 10.1161/CIRCULATIONAHA.115.019692. Epub 2016 Jun 28.

29.

Rho Kinases and Cardiac Remodeling.

Shimizu T, Liao JK.

Circ J. 2016 Jun 24;80(7):1491-8. doi: 10.1253/circj.CJ-16-0433. Epub 2016 Jun 1. Review.

30.
31.

Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma.

Lennon FE, Cianci GC, Kanteti R, Riehm JJ, Arif Q, Poroyko VA, Lupovitch E, Vigneswaran W, Husain A, Chen P, Liao JK, Sattler M, Kindler HL, Salgia R.

Sci Rep. 2016 Apr 15;6:24578. doi: 10.1038/srep24578.

32.

Relative Lack of Culprit and Obstructive Coronary Lesions in Patients With Acute Ischemic Stroke and Elevated Cardiac Troponin.

Hofmann Bowman MA, Liao JK.

Circulation. 2016 Mar 29;133(13):1228-9. doi: 10.1161/CIRCULATIONAHA.116.021795. Epub 2016 Mar 1. No abstract available.

33.

Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease.

Girard R, Khanna O, Shenkar R, Zhang L, Wu M, Jesselson M, Zeineddine HA, Gangal A, Fam MD, Gibson CC, Whitehead KJ, Li DY, Liao JK, Shi C, Awad IA.

Biomark Med. 2016;10(3):255-64. doi: 10.2217/bmm.15.118. Epub 2016 Feb 9.

34.

The Performance Analysis of the Map-Aided Fuzzy Decision Tree Based on the Pedestrian Dead Reckoning Algorithm in an Indoor Environment.

Chiang KW, Liao JK, Tsai GJ, Chang HW.

Sensors (Basel). 2015 Dec 28;16(1). pii: E34. doi: 10.3390/s16010034.

35.

The Effect of Reading Aloud Exercises for Complete Denture Patients during the Functional Rehabilitation Period.

Liu L, Ye XH, Li JY, Liao JK, Ye JT.

J Prosthodont. 2017 Apr;26(3):201-205. doi: 10.1111/jopr.12339. Epub 2015 Sep 16.

PMID:
26375868
36.

Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome.

Kajikawa M, Noma K, Nakashima A, Maruhashi T, Iwamoto Y, Matsumoto T, Iwamoto A, Oda N, Hidaka T, Kihara Y, Aibara Y, Chayama K, Sasaki S, Kato M, Dote K, Goto C, Liao JK, Higashi Y.

Hypertension. 2015 Oct;66(4):892-9. doi: 10.1161/HYPERTENSIONAHA.115.05587. Epub 2015 Aug 17.

37.

ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice.

Kasahara DI, Mathews JA, Park CY, Cho Y, Hunt G, Wurmbrand AP, Liao JK, Shore SA.

Am J Physiol Lung Cell Mol Physiol. 2015 Oct 1;309(7):L736-46. doi: 10.1152/ajplung.00372.2014. Epub 2015 Aug 14.

38.

Effect of heating palladium-silver alloys on ceramic bond strength.

Li JY, Li RN, Chang SH, Zhuang PL, Liao JK, Ye XH, Ye JT.

J Prosthet Dent. 2015 Nov;114(5):715-24. doi: 10.1016/j.prosdent.2015.05.006. Epub 2015 Jul 26.

PMID:
26213266
39.

MnTBAP stimulates angiogenic functions in endothelial cells through mitofusin-1.

Zhou Q, Gensch C, Keller C, Schmitt H, Esser J, Moser M, Liao JK.

Vascul Pharmacol. 2015 Sep;72:163-71. doi: 10.1016/j.vph.2015.05.007. Epub 2015 May 23.

40.

Exogenous nitric oxide inhibits Rho-associated kinase activity in patients with angina pectoris: a randomized controlled trial.

Maruhashi T, Noma K, Fujimura N, Kajikawa M, Matsumoto T, Hidaka T, Nakashima A, Kihara Y, Liao JK, Higashi Y.

Hypertens Res. 2015 Jul;38(7):485-90. doi: 10.1038/hr.2015.24. Epub 2015 Mar 5.

41.

Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism.

Matsumoto T, Oki K, Kajikawa M, Nakashima A, Maruhashi T, Iwamoto Y, Iwamoto A, Oda N, Hidaka T, Kihara Y, Kohno N, Chayama K, Goto C, Aibara Y, Noma K, Liao JK, Higashi Y.

Hypertension. 2015 Apr;65(4):841-8. doi: 10.1161/HYPERTENSIONAHA.114.05001. Epub 2015 Jan 26.

42.

Two functional polymorphisms of ROCK2 enhance arterial stiffening through inhibiting its activity and expression.

Liao YC, Liu PY, Lin HF, Lin WY, Liao JK, Juo SH.

J Mol Cell Cardiol. 2015 Feb;79:180-6. doi: 10.1016/j.yjmcc.2014.11.023. Epub 2014 Dec 3.

43.

The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis.

Knipe RS, Tager AM, Liao JK.

Pharmacol Rev. 2015;67(1):103-17. doi: 10.1124/pr.114.009381. Review.

44.

Abrogation of airway hyperresponsiveness but not inflammation by rho kinase insufficiency.

Kasahara DI, Ninin FM, Wurmbrand AP, Liao JK, Shore SA.

Clin Exp Allergy. 2015 Feb;45(2):457-70. doi: 10.1111/cea.12438.

45.

Critical role of exogenous nitric oxide in ROCK activity in vascular smooth muscle cells.

Maruhashi T, Noma K, Iwamoto Y, Iwamoto A, Oda N, Kajikawa M, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Liao JK, Higashi Y.

PLoS One. 2014 Oct 3;9(10):e109017. doi: 10.1371/journal.pone.0109017. eCollection 2014.

46.

Evidence of pleiotropy by statins: leukocyte Rho kinase (ROCK) activity and pretreated statin before percutaneous coronary interventions are clinical vascular outcome predictors.

Liu PY, Lee PT, Chang WT, Tai YL, Chao TH, Lee CH, Li YH, Chen JH, Tsai LM, Liao JK.

Int J Cardiol. 2014 Sep;176(1):250-3. doi: 10.1016/j.ijcard.2014.06.059. Epub 2014 Jul 6. No abstract available.

47.

Potential serum biomarkers in the pathophysiological processes of stroke.

Miao Y, Liao JK.

Expert Rev Neurother. 2014 Feb;14(2):173-85. doi: 10.1586/14737175.2014.875471. Epub 2014 Jan 13. Review.

48.

Rho-associated kinase activity is a predictor of cardiovascular outcomes.

Kajikawa M, Noma K, Maruhashi T, Mikami S, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Liao JK, Higashi Y.

Hypertension. 2014 Apr;63(4):856-64. doi: 10.1161/HYPERTENSIONAHA.113.02296. Epub 2013 Dec 30.

49.

Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.

Zee RYL, Wang QM, Chasman DI, Ridker PM, Liao JK.

Clin Sci (Lond). 2014 Jun;126(12):829-835. doi: 10.1042/CS20130652.

50.

Effect of pretreatments on the metal-ceramic bonding strength of a Pd-Ag alloy.

Li BH, Ye JT, Liao JK, Zhuang PL, Zhang YP, Li JY.

J Dent. 2014 Mar;42(3):319-28. doi: 10.1016/j.jdent.2013.11.020. Epub 2013 Dec 4.

PMID:
24316343

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