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A rapid and sensitive UHPLC-MS/MS method for the determination of ziyuglycoside I and its application in a preliminary pharmacokinetic study in healthy and leukopenic rats.

Zhu LJ, Chen L, Bai CF, Wu AG, Liang SC, Huang FH, Cao SS, Yang L, Zou WJ, Wu JM.

Biomed Pharmacother. 2020 Mar;123:109756. doi: 10.1016/j.biopha.2019.109756. Epub 2019 Dec 25.


Tribute to Paul M. Vanhoutte, MD, PhD (1940-2019).

Boulanger CM, Baretella O, Blaise G, Bond RA, Cai Y, Chan CKY, Chataigneau T, Chen MJ, Chen H, Cheng Y, Clement DL, Cohen RA, Collis M, Danser AHJ, de Mey J, Detremmerie CMS, Duprez D, Feletou M, Flavahan N, Gao Y, Guo Y, Hoeffner U, Houston DS, Huang IB, Huang Y, Iliano S, Junquero D, Katusic ZS, Komori K, Lee MYK, Leung SWS, Li Z, Liang SC, Liu JTC, Luscher TF, Michel F, Miller VM, Mombouli JV, Morrison K, Muldoon SM, O'Rourke S, Perrault L, Quignard JF, Rusch NJ, Sanchez-Ferrer CF, Schini-Kerth V, Shen K, Shi Y, Song E, Sun KWY, Taddei S, Tang EHC, Tuncer M, van den Ende R, Vedernikov Y, Verbeuren TJ, Webb C, Weigert A, Wong KHK, Xu C, Yang K, Ying F, Zellers T, Zhao Y, Zou Q, Shimokawa H; Professor Paul M. Vanhoutte’s former fellows.

Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):2445-2447. doi: 10.1161/ATVBAHA.119.313461. Epub 2019 Nov 26. No abstract available.


[Spatial distribution patterns and association of Loropetalum chinense population in karst hills of Guilin, Southwest China].

Tu HR, Li JF, Liu RH, Liang SC, Lan ZN, Zhang XY, Kang XD, Jiang Y.

Ying Yong Sheng Tai Xue Bao. 2019 Aug;30(8):2621-2630. doi: 10.13287/j.1001-9332.201908.016. Chinese.


Inner ear function in patients with obstructive sleep apnea.

Li X, Chen WJ, Zhang XY, Liang SC, Guo ZP, Lu ML, Ye JY.

Sleep Breath. 2020 Mar;24(1):65-69. doi: 10.1007/s11325-019-01891-7. Epub 2019 Jul 16.


[Interspecific associations of the main tree populations of the Cyclobalanopsis glauca community in Karst hills of Guilin, Southwest China].

Tu HR, Li JF, Yang LT, Bai JL, Lu GQ, Li HC, Liang SC, Jiang Y.

Ying Yong Sheng Tai Xue Bao. 2019 Jan 20;30(1):67-76. doi: 10.13287/j.1001-9332.201901.018. Chinese.


PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8+ T-cell Function.

Whelan S, Ophir E, Kotturi MF, Levy O, Ganguly S, Leung L, Vaknin I, Kumar S, Dassa L, Hansen K, Bernados D, Murter B, Soni A, Taube JM, Fader AN, Wang TL, Shih IM, White M, Pardoll DM, Liang SC.

Cancer Immunol Res. 2019 Feb;7(2):257-268. doi: 10.1158/2326-6066.CIR-18-0442. Epub 2019 Jan 18.


ILDR2 Is a Novel B7-like Protein That Negatively Regulates T Cell Responses.

Hecht I, Toporik A, Podojil JR, Vaknin I, Cojocaru G, Oren A, Aizman E, Liang SC, Leung L, Dicken Y, Novik A, Marbach-Bar N, Elmesmari A, Tange C, Gilmour A, McIntyre D, Kurowska-Stolarska M, McNamee K, Leitner J, Greenwald S, Dassa L, Levine Z, Steinberger P, Williams RO, Miller SD, McInnes IB, Neria E, Rotman G.

J Immunol. 2018 Mar 15;200(6):2025-2037. doi: 10.4049/jimmunol.1700325. Epub 2018 Feb 5.


[Clinical analysis of 76 cases of sentinel lymph node detection in cervical cancer and endometrial cancer].

Liang SC, Wang ZQ, Wang JL.

Zhonghua Fu Chan Ke Za Zhi. 2017 Sep 25;52(9):605-611. doi: 10.3760/cma.j.issn.0529-567X.2017.09.006. Chinese.


[Effect of intermittent fasting on physiology and gut microbiota in presenium rats].

Rong ZH, Liang SC, Lu JQ, He Y, Luo YM, You C, Xia GH, M P, Li P, Zhou HW.

Nan Fang Yi Ke Da Xue Xue Bao. 2016 Apr 20;37(4):423-430. Chinese.


[In vitro metabolism of daphnetin in rat liver S9 fractions].

Liang SC, Ge GB, Xia YL, Qi XY, Wang AX, Tu CX, Yang L.

Yao Xue Xue Bao. 2017 Feb;52(2):291-5. Chinese.


Isoindoline nitroxide-labeled porphyrins as potential fluorescence-suppressed spin probes.

Liu F, Zou TJ, Tan ZL, Chen S, Wu ZH, Yan GP, Zhang Q, Liang SC, Yang J.

Org Biomol Chem. 2017 Feb 7;15(5):1245-1253. doi: 10.1039/c6ob02748b. Epub 2017 Jan 18.


Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites.

Liang SC, Ge GB, Xia YL, Pei-Pei D, Ping W, Qi XY, Cai-Xia T, Ling Y.

Xenobiotica. 2017 Jun;47(6):498-504. doi: 10.1080/00498254.2016.1204567. Epub 2016 Jul 20.


Correction: Kicking against the PRCs--A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.

Liang SC, Hartwig B, Perera P, Mora-García S, de Leau E, Thornton H, de Lima Alves F, Rappsilber J, Yang S, James GV, Schneeberger K, Finnegan EJ, Turck F, Goodrich J.

PLoS Genet. 2016 Feb 19;12(2):e1005812. doi: 10.1371/journal.pgen.1005812. eCollection 2016 Feb. No abstract available.


Methylation, Glucuronidation, and Sulfonation of Daphnetin in Human Hepatic Preparations In Vitro: Metabolic Profiling, Pathway Comparison, and Bioactivity Analysis.

Liang SC, Xia YL, Hou J, Ge GB, Zhang JW, He YQ, Wang JY, Qi XY, Yang L.

J Pharm Sci. 2016 Feb;105(2):808-816. doi: 10.1016/j.xphs.2015.10.010. Epub 2016 Jan 6.


Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.

Liang SC, Hartwig B, Perera P, Mora-García S, de Leau E, Thornton H, de Lima Alves F, Rappsilber J, Yang S, James GV, Schneeberger K, Finnegan EJ, Turck F, Goodrich J.

PLoS Genet. 2015 Dec 7;11(12):e1005660. doi: 10.1371/journal.pgen.1005660. eCollection 2015 Dec. Erratum in: PLoS Genet. 2016 Feb;12(2):e1005812. de Alves, Flavia Lima [corrected to de Lima Alves, Flavia]; Rapsilber, Juri [corrected to Rappsilber, Juri].


Interleukin-4 receptor-targeted liposomal doxorubicin as a model for enhancing cellular uptake and antitumor efficacy in murine colorectal cancer.

Yang CY, Liu HW, Tsai YC, Tseng JY, Liang SC, Chen CY, Lian WN, Wei MC, Lu M, Lu RH, Lin CH, Jiang JK.

Cancer Biol Ther. 2015;16(11):1641-50. doi: 10.1080/15384047.2015.1095397. Epub 2015 Oct 5.


Investigation of the Optoelectronic Properties of Ti-doped Indium Tin Oxide Thin Film.

Pu NW, Liu WS, Cheng HM, Hu HC, Hsieh WT, Yu HW, Liang SC.

Materials (Basel). 2015 Sep 21;8(9):6471-6481. doi: 10.3390/ma8095316.


GFP Loss-of-Function Mutations in Arabidopsis thaliana.

Fu JL, Kanno T, Liang SC, Matzke AJ, Matzke M.

G3 (Bethesda). 2015 Jul 6;5(9):1849-55. doi: 10.1534/g3.115.019604.


In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis.

Liang SC, Ge GB, Xia YL, Zhang JW, Qi XY, Tu CX, Yang L.

J Pharm Sci. 2015 Oct;104(10):3557-64. doi: 10.1002/jps.24538. Epub 2015 Jun 17.


Identifying and applying a highly selective probe to simultaneously determine the O-glucuronidation activity of human UGT1A3 and UGT1A4.

Jiang L, Liang SC, Wang C, Ge GB, Huo XK, Qi XY, Deng S, Liu KX, Ma XC.

Sci Rep. 2015 Apr 17;5:9627. doi: 10.1038/srep09627.


An Rtf2 Domain-Containing Protein Influences Pre-mRNA Splicing and Is Essential for Embryonic Development in Arabidopsis thaliana.

Sasaki T, Kanno T, Liang SC, Chen PY, Liao WW, Lin WD, Matzke AJ, Matzke M.

Genetics. 2015 Jun;200(2):523-35. doi: 10.1534/genetics.115.176438. Epub 2015 Mar 27.


ABCG2 localizes to the nucleus and modulates CDH1 expression in lung cancer cells.

Liang SC, Yang CY, Tseng JY, Wang HL, Tung CY, Liu HW, Chen CY, Yeh YC, Chou TY, Yang MH, Whang-Peng J, Lin CH.

Neoplasia. 2015 Mar;17(3):265-78. doi: 10.1016/j.neo.2015.01.004.


Structural modifications at the C-4 position strongly affect the glucuronidation of 6,7-dihydroxycoumarins.

Xia YL, Ge GB, Wang P, Liang SC, He YQ, Ning J, Qian XK, Li Y, Yang L.

Drug Metab Dispos. 2015 Apr;43(4):553-60. doi: 10.1124/dmd.114.060681. Epub 2015 Jan 27.


Dynamic changes in numbers and properties of circulating tumor cells and their potential applications.

Tseng JY, Yang CY, Liang SC, Liu RS, Jiang JK, Lin CH.

Cancers (Basel). 2014 Dec 16;6(4):2369-86. doi: 10.3390/cancers6042369. Review.


Common effects of fat, ethanol, and nicotine on enkephalin in discrete areas of the brain.

Chang GQ, Karatayev O, Barson JR, Liang SC, Leibowitz SF.

Neuroscience. 2014 Sep 26;277:665-78. doi: 10.1016/j.neuroscience.2014.07.050. Epub 2014 Jul 30.


Role of EZH2 protein expression in gastric carcinogenesis among Asians: a meta-analysis.

Guo L, Yang TF, Liang SC, Guo JX, Wang Q.

Tumour Biol. 2014 Jul;35(7):6649-56. doi: 10.1007/s13277-014-1888-y. Epub 2014 Apr 5.


Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases.

Tseng JY, Yang CY, Liang SC, Liu RS, Yang SH, Lin JK, Chen YM, Wu YC, Jiang JK, Lin CH.

Clin Cancer Res. 2014 Jun 1;20(11):2885-97. doi: 10.1158/1078-0432.CCR-13-2162. Epub 2014 Mar 27.


The ability to form homodimers is essential for RDM1 to function in RNA-directed DNA methylation.

Sasaki T, Lorković ZJ, Liang SC, Matzke AJ, Matzke M.

PLoS One. 2014 Feb 3;9(2):e88190. doi: 10.1371/journal.pone.0088190. eCollection 2014.


Asian couples in negotiation: a mixed-method observational study of cultural variations across five Asian regions.

Lee WY, Nakamura S, Chung MJ, Chun YJ, Fu M, Liang SC, Liu CL.

Fam Process. 2013 Sep;52(3):499-518. doi: 10.1111/famp.12040. Epub 2013 Aug 29.


Identification and characterization of human UDP-glucuronosyltransferases responsible for the glucuronidation of fraxetin.

Xia YL, Liang SC, Zhu LL, Ge GB, He GY, Ning J, Lv X, Ma XC, Yang L, Yang SL.

Drug Metab Pharmacokinet. 2014;29(2):135-40. Epub 2013 Sep 10.


[Research progress of abnormal amygdala in autistic patients' social impairments].

Li J, Liang SC, Zhang R.

Sheng Li Ke Xue Jin Zhan. 2013 Apr;44(2):121-4. Review. Chinese. No abstract available.


Depletion of regulatory T cells by targeting folate receptor 4 enhances the potency of a GM-CSF-secreting tumor cell immunotherapy.

Liang SC, Moskalenko M, Van Roey M, Jooss K.

Clin Immunol. 2013 Aug;148(2):287-98. doi: 10.1016/j.clim.2013.05.011. Epub 2013 May 25.


Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes.

Qi XY, Liang SC, Ge GB, Liu Y, Dong PP, Zhang JW, Wang AX, Hou J, Zhu LL, Yang L, Tu CX.

Food Chem Toxicol. 2013 Jun;56:392-7. doi: 10.1016/j.fct.2013.02.054. Epub 2013 Mar 14.


The role of serum albumin in the metabolism of Boc5: molecular identification, species differences and contribution to plasma metabolism.

Ge GB, Ai CZ, Hu WB, Hou J, Zhu LL, He GY, Fang ZZ, Liang SC, Wang FY, Yang L.

Eur J Pharm Sci. 2013 Jan 23;48(1-2):360-9. doi: 10.1016/j.ejps.2012.11.011. Epub 2012 Dec 6.


[Bioaccumulation of heavy metals by the dominant plants growing in Huayuan manganese and lead/zinc mineland, Xiangxi].

Yang SX, Tian QJ, Liang SC, Zhou YY, Zou HC.

Huan Jing Ke Xue. 2012 Jun;33(6):2038-45. Chinese.


Prenatal ethanol exposure stimulates neurogenesis in hypothalamic and limbic peptide systems: possible mechanism for offspring ethanol overconsumption.

Chang GQ, Karatayev O, Liang SC, Barson JR, Leibowitz SF.

Neuroscience. 2012 Oct 11;222:417-28. doi: 10.1016/j.neuroscience.2012.05.066. Epub 2012 Jun 26.


Characteristics of cochlear microphonics in infants and young children with auditory neuropathy.

Shi W, Ji F, Lan L, Liang SC, Ding HN, Wang H, Li N, Li Q, Li XQ, Wang QJ.

Acta Otolaryngol. 2012 Feb;132(2):188-96. doi: 10.3109/00016489.2011.630016. Epub 2011 Nov 21.


Investigation of UDP-glucuronosyltransferases (UGTs) inhibitory properties of carvacrol.

Dong RH, Fang ZZ, Zhu LL, Liang SC, Ge GB, Yang L, Liu ZY.

Phytother Res. 2012 Jan;26(1):86-90. doi: 10.1002/ptr.3525. Epub 2011 May 5.


Expression of an Oncidium gene encoding a patatin-like protein delays flowering in Arabidopsis by reducing gibberellin synthesis.

Lin CC, Chu CF, Liu PH, Lin HH, Liang SC, Hsu WE, Lin JS, Wang HM, Chang LL, Chien CT, Jeng ST.

Plant Cell Physiol. 2011 Feb;52(2):421-35. doi: 10.1093/pcp/pcq206. Epub 2011 Jan 7.


Comparative metabolism of cinobufagin in liver microsomes from mouse, rat, dog, minipig, monkey, and human.

Ma XC, Ning J, Ge GB, Liang SC, Wang XL, Zhang BJ, Huang SS, Li JK, Yang L.

Drug Metab Dispos. 2011 Apr;39(4):675-82. doi: 10.1124/dmd.110.036830. Epub 2011 Jan 4.


[Research advances in denitrogenation characteristics of aerobic denitrifiers].

Liang SC, Zhao M, Lu L, Zhao LY.

Ying Yong Sheng Tai Xue Bao. 2010 Jun;21(6):1581-8. Review. Chinese.


IL-22 induces an acute-phase response.

Liang SC, Nickerson-Nutter C, Pittman DD, Carrier Y, Goodwin DG, Shields KM, Lambert AJ, Schelling SH, Medley QG, Ma HL, Collins M, Dunussi-Joannopoulos K, Fouser LA.

J Immunol. 2010 Nov 1;185(9):5531-8. doi: 10.4049/jimmunol.0904091. Epub 2010 Sep 24.


Determination of propofol UDP-glucuronosyltransferase (UGT) activities in hepatic microsomes from different species by UFLC-ESI-MS.

Liang SC, Ge GB, Liu HX, Shang HT, Wei H, Fang ZZ, Zhu LL, Mao YX, Yang L.

J Pharm Biomed Anal. 2011 Jan 5;54(1):236-41. doi: 10.1016/j.jpba.2010.07.049. Epub 2010 Aug 13.


Progressive renal distortion by multiple cysts in transgenic mice expressing artificial microRNAs against Pkd1.

Wang E, Hsieh-Li HM, Chiou YY, Chien YL, Ho HH, Chin HJ, Wang CK, Liang SC, Jiang ST.

J Pathol. 2010 Nov;222(3):238-48. doi: 10.1002/path.2765.


Identification of cytochrome P450 (CYP) isoforms involved in the metabolism of corynoline, and assessment of its herb-drug interactions.

Fang ZZ, Zhang YY, Ge GB, Liang SC, Sun DX, Zhu LL, Dong PP, Cao YF, Yang L.

Phytother Res. 2011 Feb;25(2):256-63. doi: 10.1002/ptr.3255.


Rapid qualitative and quantitative determination of seven valuable taxanes from various Taxus species by UFLC-ESI-MS and UFLC-DAD.

Ge GB, Liang SC, Hu Y, Liu XB, Mao YX, Zhang YY, Luan HW, Qiu MH, Yang L.

Planta Med. 2010 Oct;76(15):1773-7. doi: 10.1055/s-0030-1249959. Epub 2010 May 26.


Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS.

Wang AX, Ge GB, Qi XY, Hu Y, Liang SC, Yang L, Tu CX.

Fitoterapia. 2010 Sep;81(6):662-7. doi: 10.1016/j.fitote.2010.03.016. Epub 2010 Mar 31.


Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction.

Fang ZZ, Zhang YY, Ge GB, Huo H, Liang SC, Yang L.

Br J Clin Pharmacol. 2010 Feb;69(2):193-9. doi: 10.1111/j.1365-2125.2009.03572.x.


Identification and characterization of human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of daphnetin.

Liang SC, Ge GB, Liu HX, Zhang YY, Wang LM, Zhang JW, Yin L, Li W, Fang ZZ, Wu JJ, Li GH, Yang L.

Drug Metab Dispos. 2010 Jun;38(6):973-80. doi: 10.1124/dmd.109.030734. Epub 2010 Feb 22.


Microbial contaminations of laboratory mice and rats in Taiwan from 2004 to 2007.

Liang CT, Shih A, Chang YH, Liu CW, Lee YT, Hsieh WC, Huang YL, Huang WT, Kuang CH, Lee KH, Zhuo YX, Ho SY, Liao SL, Chiu YY, Hsu CN, Liang SC, Yu CK.

J Am Assoc Lab Anim Sci. 2009 Jul;48(4):381-6.

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