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Items: 1 to 50 of 55

1.

Global smoking trends in inflammatory bowel disease: A systematic review of inception cohorts.

Thomas T, Chandan JS, Li VSW, Lai CY, Tang W, Bhala N, Kaplan GG, Ng SC, Ghosh S.

PLoS One. 2019 Sep 23;14(9):e0221961. doi: 10.1371/journal.pone.0221961. eCollection 2019.

2.

Tissue-Engineering the Intestine: The Trials before the Trials.

Clevers H, Conder RK, Li VSW, Lutolf MP, Vallier L, Chan S, Grikscheit TC, Jensen KB, De Coppi P.

Cell Stem Cell. 2019 Jun 6;24(6):855-859. doi: 10.1016/j.stem.2019.04.018.

PMID:
31173715
3.

Yap in regeneration and symmetry breaking.

Li VSW.

Nat Cell Biol. 2019 Jun;21(6):665-667. doi: 10.1038/s41556-019-0334-1. No abstract available.

PMID:
31086262
4.

SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization.

Antas P, Novellasdemunt L, Kucharska A, Massie I, Carvalho J, Oukrif D, Nye E, Novelli M, Li VSW.

Cell Rep. 2019 Feb 26;26(9):2266-2273.e4. doi: 10.1016/j.celrep.2019.01.110.

5.

Profiling proliferative cells and their progeny in damaged murine hearts.

Kretzschmar K, Post Y, Bannier-Hélaouët M, Mattiotti A, Drost J, Basak O, Li VSW, van den Born M, Gunst QD, Versteeg D, Kooijman L, van der Elst S, van Es JH, van Rooij E, van den Hoff MJB, Clevers H.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12245-E12254. doi: 10.1073/pnas.1805829115. Epub 2018 Dec 7.

6.

Pak1 Kinase Maintains Apical Membrane Identity in Epithelia.

Aguilar-Aragon M, Elbediwy A, Foglizzo V, Fletcher GC, Li VSW, Thompson BJ.

Cell Rep. 2018 Feb 13;22(7):1639-1646. doi: 10.1016/j.celrep.2018.01.060.

7.

NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease.

Schwerd T, Bryant RV, Pandey S, Capitani M, Meran L, Cazier JB, Jung J, Mondal K, Parkes M, Mathew CG, Fiedler K, McCarthy DJ; WGS500 Consortium; Oxford IBD cohort study investigators; COLORS in IBD group investigators; UK IBD Genetics Consortium, Sullivan PB, Rodrigues A, Travis SPL, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J; INTERVAL Study, Russell RK, Wilson DC, Kelsen JR, Cornall R, Denson LA, Kugathasan S, Knaus UG, Serra EG, Anderson CA, Duerr RH, McGovern DP, Cho J, Powrie F, Li VS, Muise AM, Uhlig HH.

Mucosal Immunol. 2018 Mar;11(2):562-574. doi: 10.1038/mi.2017.74. Epub 2017 Nov 1.

8.

USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.

Novellasdemunt L, Foglizzo V, Cuadrado L, Antas P, Kucharska A, Encheva V, Snijders AP, Li VSW.

Cell Rep. 2017 Oct 17;21(3):612-627. doi: 10.1016/j.celrep.2017.09.072.

9.

Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components.

Meran L, Baulies A, Li VSW.

Stem Cells Int. 2017;2017:7970385. doi: 10.1155/2017/7970385. Epub 2017 Aug 1. Review.

10.

Correction: The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis.

Mahmoudi T, Boj SF, Hatzis P, Li VS, Taouatas N, Vries RG, Teunissen H, Begthel H, Korving J, Mohammed S, Heck AJ, Clevers H.

PLoS Biol. 2017 Feb 7;15(2):e1002596. doi: 10.1371/journal.pbio.1002596. eCollection 2017 Feb.

11.

Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon.

Sasaki N, Sachs N, Wiebrands K, Ellenbroek SI, Fumagalli A, Lyubimova A, Begthel H, van den Born M, van Es JH, Karthaus WR, Li VS, López-Iglesias C, Peters PJ, van Rheenen J, van Oudenaarden A, Clevers H.

Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5399-407. doi: 10.1073/pnas.1607327113. Epub 2016 Aug 29.

12.

Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms.

Novellasdemunt L, Antas P, Li VS.

Am J Physiol Cell Physiol. 2015 Oct 15;309(8):C511-21. doi: 10.1152/ajpcell.00117.2015. Epub 2015 Aug 19. Review.

13.

Prospective derivation of a living organoid biobank of colorectal cancer patients.

van de Wetering M, Francies HE, Francis JM, Bounova G, Iorio F, Pronk A, van Houdt W, van Gorp J, Taylor-Weiner A, Kester L, McLaren-Douglas A, Blokker J, Jaksani S, Bartfeld S, Volckman R, van Sluis P, Li VS, Seepo S, Sekhar Pedamallu C, Cibulskis K, Carter SL, McKenna A, Lawrence MS, Lichtenstein L, Stewart C, Koster J, Versteeg R, van Oudenaarden A, Saez-Rodriguez J, Vries RG, Getz G, Wessels L, Stratton MR, McDermott U, Meyerson M, Garnett MJ, Clevers H.

Cell. 2015 May 7;161(4):933-45. doi: 10.1016/j.cell.2015.03.053.

14.

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.

Wang K, Yuen ST, Xu J, Lee SP, Yan HH, Shi ST, Siu HC, Deng S, Chu KM, Law S, Chan KH, Chan AS, Tsui WY, Ho SL, Chan AK, Man JL, Foglizzo V, Ng MK, Chan AS, Ching YP, Cheng GH, Xie T, Fernandez J, Li VS, Clevers H, Rejto PA, Mao M, Leung SY.

Nat Genet. 2014 Jun;46(6):573-82. doi: 10.1038/ng.2983. Epub 2014 May 11.

PMID:
24816253
15.

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.

Huch M, Bonfanti P, Boj SF, Sato T, Loomans CJ, van de Wetering M, Sojoodi M, Li VS, Schuijers J, Gracanin A, Ringnalda F, Begthel H, Hamer K, Mulder J, van Es JH, de Koning E, Vries RG, Heimberg H, Clevers H.

EMBO J. 2013 Oct 16;32(20):2708-21. doi: 10.1038/emboj.2013.204. Epub 2013 Sep 17.

16.

Platelet-derived growth factor-D promotes fibrogenesis of cardiac fibroblasts.

Zhao T, Zhao W, Chen Y, Li VS, Meng W, Sun Y.

Am J Physiol Heart Circ Physiol. 2013 Jun 15;304(12):H1719-26. doi: 10.1152/ajpheart.00130.2013. Epub 2013 Apr 12.

17.

Intestinal regeneration: YAP-tumor suppressor and oncoprotein?

Li VS, Clevers H.

Curr Biol. 2013 Feb 4;23(3):R110-2. doi: 10.1016/j.cub.2012.12.021.

18.

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

Huch M, Dorrell C, Boj SF, van Es JH, Li VS, van de Wetering M, Sato T, Hamer K, Sasaki N, Finegold MJ, Haft A, Vries RG, Grompe M, Clevers H.

Nature. 2013 Feb 14;494(7436):247-50. doi: 10.1038/nature11826. Epub 2013 Jan 27.

19.

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.

Boj SF, van Es JH, Huch M, Li VS, José A, Hatzis P, Mokry M, Haegebarth A, van den Born M, Chambon P, Voshol P, Dor Y, Cuppen E, Fillat C, Clevers H.

Cell. 2012 Dec 21;151(7):1595-607. doi: 10.1016/j.cell.2012.10.053.

20.

Peyer's patch M cells derived from Lgr5(+) stem cells require SpiB and are induced by RankL in cultured "miniguts".

de Lau W, Kujala P, Schneeberger K, Middendorp S, Li VS, Barker N, Martens A, Hofhuis F, DeKoter RP, Peters PJ, Nieuwenhuis E, Clevers H.

Mol Cell Biol. 2012 Sep;32(18):3639-47. doi: 10.1128/MCB.00434-12. Epub 2012 Jul 9.

21.

Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.

Li VS, Ng SS, Boersema PJ, Low TY, Karthaus WR, Gerlach JP, Mohammed S, Heck AJ, Maurice MM, Mahmoudi T, Clevers H.

Cell. 2012 Jun 8;149(6):1245-56. doi: 10.1016/j.cell.2012.05.002.

22.

In vitro expansion and transplantation of intestinal crypt stem cells.

Li VS, Clevers H.

Gastroenterology. 2012 Jul;143(1):30-4. doi: 10.1053/j.gastro.2012.05.017. Epub 2012 May 18. Review. No abstract available.

PMID:
22613623
23.

The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis.

Sylva M, Li VS, Buffing AA, van Es JH, van den Born M, van der Velden S, Gunst Q, Koolstra JH, Moorman AF, Clevers H, van den Hoff MJ.

PLoS One. 2011;6(8):e22616. doi: 10.1371/journal.pone.0022616. Epub 2011 Aug 3.

24.

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.

de Lau W, Barker N, Low TY, Koo BK, Li VS, Teunissen H, Kujala P, Haegebarth A, Peters PJ, van de Wetering M, Stange DE, van Es JE, Guardavaccaro D, Schasfoort RB, Mohri Y, Nishimori K, Mohammed S, Heck AJ, Clevers H.

Nature. 2011 Jul 4;476(7360):293-7. doi: 10.1038/nature10337.

PMID:
21727895
25.

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.

Mahmoudi T, Boj SF, Hatzis P, Li VS, Taouatas N, Vries RG, Teunissen H, Begthel H, Korving J, Mohammed S, Heck AJ, Clevers H.

PLoS Biol. 2010 Nov 16;8(11):e1000539. doi: 10.1371/journal.pbio.1000539. Erratum in: PLoS Biol. 2017 Feb 7;15(2):e1002596.

26.

MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway.

Sue Ng S, Mahmoudi T, Li VS, Hatzis P, Boersema PJ, Mohammed S, Heck AJ, Clevers H.

Biol Chem. 2010 Feb-Mar;391(2-3):171-80. doi: 10.1515/BC.2010.028.

PMID:
20128690
27.

The kinase TNIK is an essential activator of Wnt target genes.

Mahmoudi T, Li VS, Ng SS, Taouatas N, Vries RG, Mohammed S, Heck AJ, Clevers H.

EMBO J. 2009 Nov 4;28(21):3329-40. doi: 10.1038/emboj.2009.285. Epub 2009 Oct 8.

28.

Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms.

Li VS, Yuen ST, Chan TL, Yan HH, Law WL, Yeung BH, Chan AS, Tsui WY, So S, Chen X, Leung SY.

Gastroenterology. 2009 Jul;137(1):176-87. doi: 10.1053/j.gastro.2009.03.005. Epub 2009 Mar 18.

PMID:
19303019
29.

Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors.

Kosinski C, Li VS, Chan AS, Zhang J, Ho C, Tsui WY, Chan TL, Mifflin RC, Powell DW, Yuen ST, Leung SY, Chen X.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15418-23. Epub 2007 Sep 19.

30.

Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer.

Chan TL, Yuen ST, Kong CK, Chan YW, Chan AS, Ng WF, Tsui WY, Lo MW, Tam WY, Li VS, Leung SY.

Nat Genet. 2006 Oct;38(10):1178-83. Epub 2006 Sep 3.

PMID:
16951683
31.

Mutations of PIK3CA in gastric adenocarcinoma.

Li VS, Wong CW, Chan TL, Chan AS, Zhao W, Chu KM, So S, Chen X, Yuen ST, Leung SY.

BMC Cancer. 2005 Mar 23;5:29.

32.

Synthetic enantiopure aziridinomitosenes: preparation, reactivity, and DNA alkylation studies.

Vedejs E, Naidu BN, Klapars A, Warner DL, Li VS, Na Y, Kohn H.

J Am Chem Soc. 2003 Dec 24;125(51):15796-806.

PMID:
14677970
33.
34.

Synthesis, DNA cross-linking activity, and cytotoxicity of dimeric mitomycins.

Na Y, Li VS, Nakanishi Y, Bastow KF, Kohn H.

J Med Chem. 2001 Oct 11;44(21):3453-62.

PMID:
11585450
35.

The effect of C(5) cytosine methylation at CpG sequences on mitomycin-DNA bonding profiles.

Li VS, Tang MS, Kohn H.

Bioorg Med Chem. 2001 Apr;9(4):863-73.

PMID:
11354669
36.

C5 cytosine methylation at CpG sites enhances sequence selectivity of mitomycin C-DNA bonding.

Li VS, Reed M, Zheng Y, Kohn H, Tang M.

Biochemistry. 2000 Mar 14;39(10):2612-8.

PMID:
10704210
37.

[Stimulation of regenerative processes and correction of the functional activity of the liver in its partial resection and toxic lesions].

Abakumova OIu, Kutsenko NG, Fedorova LM, Podobed OV, Gavril'chak AV, Shekhter AB, Kovaleva GG, Popov AA, Li VS, Karagiulian SR, Mitina VKh, Kliashchitskiĭ BA.

Vestn Ross Akad Med Nauk. 1996;(5):36-41. Russian.

PMID:
8924825
38.

Structural requirements for mitomycin C DNA bonding.

Li VS, Choi D, Tang MS, Kohn H.

Biochemistry. 1995 May 30;34(21):7120-6.

PMID:
7766622
39.

[The effect of covalently and noncovalently bound complexes of albumin with bilirubin on DNA and protein synthesis in liver and spleen of rats subjected to splenectomy and partial hepatectomy].

Abakumova OIu, Fedorova LM, Popov AA, Kutsenko NG, Li VS, Mitina VKh, Kliashchitskiĭ BA, Bachmanova GI.

Vopr Med Khim. 1995 Jan-Feb;41(1):9-13. Russian.

PMID:
7771097
40.

Effects of albumin-bilirubin complexes with syngeneic or allogeneic albumin on DNA and protein synthesis in liver and spleen of partially hepatectomized rats.

Abakumova OYu, Fedorova LM, Popov AA, Li VS, Arkhangelskaya SL, Bachmanova GI.

J Hepatol. 1994 Dec;21(6):947-52.

PMID:
7699258
41.

[Antioxidative properties of glycyrrhyzic acid salts and their effect on the liver monooxygenase system].

Abdugafurova MA, Li VS, Sherstnev MP, Atanaev TB, Isamukhamedov ASh, Bachmanova GI.

Vopr Med Khim. 1990 Sep-Oct;36(5):29-31. Russian.

PMID:
2251786
42.
44.

Influence of cholesterol and prostaglandin E1 on the molecular organization of phospholipids in the erythrocyte membrane. A fluorescent polarization study with lipid-specific probes.

Manevich EM, Lakin KM, Archakov AI, Li VS, Molotkovsky JG, Bezuglov VV, Bergelson LD.

Biochim Biophys Acta. 1985 May 28;815(3):455-60.

PMID:
4039606
45.

Phosphinic Acid analogues of methylaspartic and methylglutamic acids as antibacterials.

Cates LA, Li VS.

Pharm Res. 1985 May;2(3):135-6. doi: 10.1023/A:1016315400847.

PMID:
24272691
47.

Excitatory amino acid receptor interactions of a novel alpha-phosphinic acid analogue of alpha-methylaspartic acid.

Cates LA, Li VS, Hu ZS, Lehmann J, Coyle JT, Ferkany JW.

J Pharm Sci. 1984 Nov;73(11):1550-3.

PMID:
6151596
48.

Phosphorus analogues of gamma-aminobutyric acid, a new class of anticonvulsants.

Cates LA, Li VS, Yakshe CC, Fadeyi MO, Andree TH, Karbon EW, Enna SJ.

J Med Chem. 1984 May;27(5):654-9.

PMID:
6325692
49.

Phosphorus-nitrogen compounds. 24. Phosphoramide mustard carrier derivatives.

Cates LA, Li VS, Powell DR, van der Helm D.

J Med Chem. 1984 Mar;27(3):397-401.

PMID:
6699885
50.

[Lipid composition and structure-functional properties of membranes of erythrocytes of different ages].

Li VS, Khalilov EM, Saburova VI, Gorbatenkova EA, Azizova OA.

Vopr Med Khim. 1982 Nov-Dec;28(6):66-71. Russian.

PMID:
7157723

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