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Short-Term Appraisal of the Effects and Safety of Manual Versus Ventilator Hyperinflation in an Animal Model of Severe Pneumonia.

Li Bassi G, Martí JD, Comaru T, Aguilera-Xiol E, Rigol M, Ntoumenopoulos G, Terraneo S, De Rosa F, Rinaudo M, Fernandez-Barat L, Battaglini D, Meli A, Ferrer M, Pelosi P, Chiumello D, Torres A.

Respir Care. 2019 Jul;64(7):760-770. doi: 10.4187/respcare.06487. Epub 2019 May 14.


Nebulized Amikacin and Fosfomycin for Severe Pseudomonas aeruginosa Pneumonia: An Experimental Study.

Li Bassi G, Motos A, Fernandez-Barat L, Aguilera Xiol E, Chiurazzi C, Senussi T, Saco MA, Fuster C, Carbonara M, Bobi J, Amaro R, De Rosa F, Comaru T, Yang H, Ranzani OT, Marti JD, Rinaudo M, Comino Trinidad O, Rigol M, Bringué J, Ramirez J, Nicolau DP, Pelosi P, Antonelli M, Blasi F, Artigas A, Montgomery AB, Torres A.

Crit Care Med. 2019 Jun;47(6):e470-e477. doi: 10.1097/CCM.0000000000003724.


An in-vitro study to evaluate high-volume low-pressure endotracheal tube cuff deflation dynamics.

Marti JD, Li Bassi G, Isetta V, Lazaro MR, Aguilera-Xiol E, Comaru T, Battaglini D, Meli A, Ferrer M, Navajas D, Pelosi P, Chiumello D, Torres A, Farre R.

Minerva Anestesiol. 2019 Mar 12. doi: 10.23736/S0375-9393.19.13133-1. [Epub ahead of print]


Invasive and non-invasive diagnostic approaches for microbiological diagnosis of hospital-acquired pneumonia.

Ranzani OT, Senussi T, Idone F, Ceccato A, Li Bassi G, Ferrer M, Torres A.

Crit Care. 2019 Feb 18;23(1):51. doi: 10.1186/s13054-019-2348-2.


Recruitment manoeuvres dislodge mucus towards the distal airways in an experimental model of severe pneumonia.

Li Bassi G, Comaru T, Martí D, Xiol EA, Chiurazzi C, Travierso C, Carbonara M, Ranzani OT, Amaro R, Frigola G, Fuster C, Saco MA, Zanella A, De Rosa F, Rigol M, Fernandez L, Luque N, Ramirez J, Blasi F, Suen J, Fraser J, Torres A.

Br J Anaesth. 2019 Feb;122(2):269-276. doi: 10.1016/j.bja.2018.07.039. Epub 2018 Nov 10.


Inhaled amikacin for severe Gram-negative pulmonary infections in the intensive care unit: current status and future prospects.

Torres A, Motos A, Battaglini D, Li Bassi G.

Crit Care. 2018 Dec 17;22(1):343. doi: 10.1186/s13054-018-1958-4. Review.


Is One Sample Enough? β-Lactam Target Attainment and Penetration into Epithelial Lining Fluid Based on Multiple Bronchoalveolar Lavage Sampling Time Points in a Swine Pneumonia Model.

Motos A, Kuti JL, Li Bassi G, Torres A, Nicolau DP.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01922-18. doi: 10.1128/AAC.01922-18. Print 2019 Feb.


Appraisal of systemic inflammation and diagnostic markers in a porcine model of VAP: secondary analysis from a study on novel preventive strategies.

Li Bassi G, Prats RG, Artigas A, Xiol EA, Marti JD, Ranzani OT, Rigol M, Fernandez L, Meli A, Battaglini D, Luque N, Ferrer M, Martin-Loeches I, Póvoa P, Chiumello D, Pelosi P, Torres A.

Intensive Care Med Exp. 2018 Oct 20;6(1):42. doi: 10.1186/s40635-018-0206-1.


In-vitro analysis of a novel 'add-on' silicone cuff to improve sealing properties of tracheal tubes.

Li Bassi G, Chiurazzi C, Aguilera E, Travierso C, Battaglini D, Yang M, Motos A, Yang H, Meli A, Marti D, Ranzani OT, Blasi F, Pelosi P, Chiumello D, Torres A.

Anaesthesia. 2018 Nov;73(11):1372-1381. doi: 10.1111/anae.14413.


Assessment of in vivo versus in vitro biofilm formation of clinical methicillin-resistant Staphylococcus aureus isolates from endotracheal tubes.

Fernández-Barat L, Ben-Aicha S, Motos A, Vila J, Marco F, Rigol M, Muñoz L, Li Bassi G, Ferrer M, Torres A.

Sci Rep. 2018 Aug 9;8(1):11906. doi: 10.1038/s41598-018-30494-7.


Summary of the international clinical guidelines for the management of hospital-acquired and ventilator-acquired pneumonia.

Torres A, Niederman MS, Chastre J, Ewig S, Fernandez-Vandellos P, Hanberger H, Kollef M, Li Bassi G, Luna CM, Martin-Loeches I, Paiva JA, Read RC, Rigau D, François Timsit J, Welte T, Wunderink R.

ERJ Open Res. 2018 Jun 26;4(2). pii: 00028-2018. doi: 10.1183/23120541.00028-2018. eCollection 2018 Apr.


Is Less More or Is It a Call for Evidence-Based Guidance?

Meli A, Pagliara F, Li Bassi G.

Respir Care. 2018 May;63(5):632-634. doi: 10.4187/respcare.06285. No abstract available.


Randomized, multicenter trial of lateral Trendelenburg versus semirecumbent body position for the prevention of ventilator-associated pneumonia.

Li Bassi G, Panigada M, Ranzani OT, Zanella A, Berra L, Cressoni M, Parrini V, Kandil H, Salati G, Selvaggi P, Amatu A, Sanz-Moncosi M, Biagioni E, Tagliaferri F, Furia M, Mercurio G, Costa A, Manca T, Lindau S, Babel J, Cavana M, Chiurazzi C, Marti JD, Consonni D, Gattinoni L, Pesenti A, Wiener-Kronish J, Bruschi C, Ballotta A, Salsi P, Livigni S, Iotti G, Fernandez J, Girardis M, Barbagallo M, Moise G, Antonelli M, Caspani ML, Vezzani A, Meybohm P, Gasparovic V, Geat E, Amato M, Niederman M, Kolobow T, Torres A; Gravity-VAP Network.

Intensive Care Med. 2017 Nov;43(11):1572-1584. doi: 10.1007/s00134-017-4858-1. Epub 2017 Jun 20.


Evaluation of the 2016 Infectious Diseases Society of America/American Thoracic Society Guideline Criteria for Risk of Multidrug-Resistant Pathogens in Patients with Hospital-acquired and Ventilator-associated Pneumonia in the ICU.

Ekren PK, Ranzani OT, Ceccato A, Li Bassi G, Muñoz Conejero E, Ferrer M, Niederman MS, Torres A.

Am J Respir Crit Care Med. 2018 Mar 15;197(6):826-830. doi: 10.1164/rccm.201708-1717LE. No abstract available.


Prevention of ventilator-associated pneumonia.

Li Bassi G, Senussi T, Aguilera Xiol E.

Curr Opin Infect Dis. 2017 Apr;30(2):214-220. doi: 10.1097/QCO.0000000000000358. Review.


Intensive care unit-acquired pneumonia due to Pseudomonas aeruginosa with and without multidrug resistance.

Fernández-Barat L, Ferrer M, De Rosa F, Gabarrús A, Esperatti M, Terraneo S, Rinaudo M, Li Bassi G, Torres A.

J Infect. 2017 Feb;74(2):142-152. doi: 10.1016/j.jinf.2016.11.008. Epub 2016 Nov 16.


Prone position and VAP incidence in the PROSEVA trial: attention to the causal question when interpreting competing risk analysis.

Ranzani OT, Li Bassi G, Torres A.

Intensive Care Med. 2016 Dec;42(12):2119-2120. doi: 10.1007/s00134-016-4469-2. Epub 2016 Sep 29. No abstract available.


The effects of direct hemoperfusion using a polymyxin B-immobilized column in a pig model of severe Pseudomonas aeruginosa pneumonia.

Li Bassi G, Marti JD, Xiol EA, Comaru T, De Rosa F, Rigol M, Terraneo S, Rinaudo M, Fernandez L, Ferrer M, Torres A.

Ann Intensive Care. 2016 Dec;6(1):58. doi: 10.1186/s13613-016-0155-3. Epub 2016 Jul 5.


Polymicrobial intensive care unit-acquired pneumonia: prevalence, microbiology and outcome.

Ferrer M, Difrancesco LF, Liapikou A, Rinaudo M, Carbonara M, Li Bassi G, Gabarrus A, Torres A.

Crit Care. 2015 Dec 23;19:450. doi: 10.1186/s13054-015-1165-5.


Tracheal tube biofilm removal through a novel closed-suctioning system: an experimental study.

Aguilera Xiol E, Li Bassi G, Wyncoll D, Ntoumenopoulos G, Fernandez-Barat L, Marti JD, Comaru T, De Rosa F, Rigol M, Rinaudo M, Ferrer M, Torres A.

Br J Anaesth. 2015 Nov;115(5):775-83. doi: 10.1093/bja/aev340.


Impact of Candida spp. isolation in the respiratory tract in patients with intensive care unit-acquired pneumonia.

Terraneo S, Ferrer M, Martín-Loeches I, Esperatti M, Di Pasquale M, Giunta V, Rinaudo M, de Rosa F, Li Bassi G, Centanni S, Torres A.

Clin Microbiol Infect. 2016 Jan;22(1):94.e1-94.e8. doi: 10.1016/j.cmi.2015.09.002. Epub 2015 Sep 12.


Endotracheal tube biofilm translocation in the lateral Trendelenburg position.

Li Bassi G, Fernandez-Barat L, Saucedo L, Giunta V, Marti JD, Tavares Ranzani O, Aguilera Xiol E, Rigol M, Roca I, Muñoz L, Luque N, Esperatti M, Saco MA, Ramirez J, Vila J, Ferrer M, Torres A.

Crit Care. 2015 Feb 27;19:59. doi: 10.1186/s13054-015-0785-0.


Impact of COPD in the outcome of ICU-acquired pneumonia with and without previous intubation.

Rinaudo M, Ferrer M, Terraneo S, De Rosa F, Peralta R, Fernández-Barat L, Li Bassi G, Torres A.

Chest. 2015 Jun;147(6):1530-1538. doi: 10.1378/chest.14-2005.


Selective digestive decontamination: a pre-emptive treatment for a few European ecological niches or a worldwide implementation?

Li Bassi G, Aguilera E.

Minerva Anestesiol. 2015 Jul;81(7):705-8. Epub 2015 Jan 19. No abstract available.


Endotracheal tubes for critically ill patients: an in vivo analysis of associated tracheal injury, mucociliary clearance, and sealing efficacy.

Li Bassi G, Luque N, Martí JD, Aguilera Xiol E, Di Pasquale M, Giunta V, Comaru T, Rigol M, Terraneo S, De Rosa F, Rinaudo M, Crisafulli E, Peralta Lepe RC, Agusti C, Lucena C, Ferrer M, Fernández L, Torres A.

Chest. 2015 May;147(5):1327-1335. doi: 10.1378/chest.14-1438.


Resistance patterns and outcomes in intensive care unit (ICU)-acquired pneumonia. Validation of European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC) classification of multidrug resistant organisms.

Martin-Loeches I, Torres A, Rinaudo M, Terraneo S, de Rosa F, Ramirez P, Diaz E, Fernández-Barat L, Li Bassi GL, Ferrer M.

J Infect. 2015 Mar;70(3):213-22. doi: 10.1016/j.jinf.2014.10.004. Epub 2014 Oct 27.


Gravity predominates over ventilatory pattern in the prevention of ventilator-associated pneumonia.

Li Bassi G, Marti JD, Saucedo L, Rigol M, Roca I, Cabanas M, Muñoz L, Ranzani OT, Giunta V, Luque N, Esperatti M, Gabarrus A, Fernandez L, Rinaudo M, Ferrer M, Ramirez J, Vila J, Torres A.

Crit Care Med. 2014 Sep;42(9):e620-7. doi: 10.1097/CCM.0000000000000487.


A novel porcine model of ventilator-associated pneumonia caused by oropharyngeal challenge with Pseudomonas aeruginosa.

Li Bassi G, Rigol M, Marti JD, Saucedo L, Ranzani OT, Roca I, Cabanas M, Muñoz L, Giunta V, Luque N, Rinaudo M, Esperatti M, Fernandez-Barat L, Ferrer M, Vila J, Ramirez J, Torres A.

Anesthesiology. 2014 May;120(5):1205-15. doi: 10.1097/ALN.0000000000000222.


Oropharyngeal decontamination with antiseptics to prevent ventilator-associated pneumonia: rethinking the benefits of povidone-iodine.

Li Bassi G, De Rosa F, Marti JD, Terraneo S.

Crit Care Med. 2014 Jan;42(1):188-90. doi: 10.1097/CCM.0b013e3182a84bcb. No abstract available.


Assessment of severity of ICU-acquired pneumonia and association with etiology.

Di Pasquale M, Ferrer M, Esperatti M, Crisafulli E, Giunta V, Li Bassi G, Rinaudo M, Blasi F, Niederman M, Torres A.

Crit Care Med. 2014 Feb;42(2):303-12. doi: 10.1097/CCM.0b013e3182a272a2.


ICU-acquired pneumonia with or without etiologic diagnosis: a comparison of outcomes.

Giunta V, Ferrer M, Esperatti M, Ranzani OT, Saucedo LM, Li Bassi G, Blasi F, Torres A.

Crit Care Med. 2013 Sep;41(9):2133-43. doi: 10.1097/CCM.0b013e31828a453b.


Validation of predictors of adverse outcomes in hospital-acquired pneumonia in the ICU.

Esperatti M, Ferrer M, Giunta V, Ranzani OT, Saucedo LM, Li Bassi G, Blasi F, Rello J, Niederman MS, Torres A.

Crit Care Med. 2013 Sep;41(9):2151-61. doi: 10.1097/CCM.0b013e31828a674a.


Effects of manual rib cage compressions on expiratory flow and mucus clearance during mechanical ventilation.

Martí JD, Li Bassi G, Rigol M, Saucedo L, Ranzani OT, Esperatti M, Luque N, Ferrer M, Vilaro J, Kolobow T, Torres A.

Crit Care Med. 2013 Mar;41(3):850-6. doi: 10.1097/CCM.0b013e3182711b52.


Systematic implementation of evidence-based guidelines in intensive care medicine: resistance to change is human nature.

Li Bassi G, Ranzani OT, Torres A.

Crit Care Med. 2013 Jan;41(1):329-31. doi: 10.1097/CCM.0b013e318270e234. No abstract available.


An in vitro study to assess determinant features associated with fluid sealing in the design of endotracheal tube cuffs and exerted tracheal pressures.

Li Bassi G, Ranzani OT, Marti JD, Giunta V, Luque N, Isetta V, Ferrer M, Farre R, Pimentel GL, Torres A.

Crit Care Med. 2013 Feb;41(2):518-26. doi: 10.1097/CCM.0b013e31826a4804.


Linezolid limits burden of methicillin-resistant Staphylococcus aureus in biofilm of tracheal tubes.

Fernández-Barat L, Ferrer M, Sierra JM, Soy D, Guerrero L, Vila J, Li Bassi G, Cortadellas N, Martínez-Olondris P, Rigol M, Esperatti M, Luque N, Saucedo LM, Agustí C, Torres A.

Crit Care Med. 2012 Aug;40(8):2385-9. doi: 10.1097/CCM.0b013e31825332fc.


Direct analysis of bacterial viability in endotracheal tube biofilm from a pig model of methicillin-resistant Staphylococcus aureus pneumonia following antimicrobial therapy.

Fernández-Barat L, Li Bassi G, Ferrer M, Bosch A, Calvo M, Vila J, Gabarrús A, Martínez-Olondris P, Rigol M, Esperatti M, Luque N, Torres A.

FEMS Immunol Med Microbiol. 2012 Jul;65(2):309-17. doi: 10.1111/j.1574-695X.2012.00961.x. Epub 2012 Apr 23.


Effects of duty cycle and positive end-expiratory pressure on mucus clearance during mechanical ventilation*.

Li Bassi G, Saucedo L, Marti JD, Rigol M, Esperatti M, Luque N, Ferrer M, Gabarrus A, Fernandez L, Kolobow T, Torres A.

Crit Care Med. 2012 Mar;40(3):895-902. doi: 10.1097/CCM.0b013e318236efb5.


Efficacy of linezolid compared to vancomycin in an experimental model of pneumonia induced by methicillin-resistant Staphylococcus aureus in ventilated pigs.

Martinez-Olondris P, Rigol M, Soy D, Guerrero L, Agusti C, Quera MA, Li Bassi G, Esperatti M, Luque N, Liapikou M, Filella X, Marco F, de la Bellacasa JP, Torres A.

Crit Care Med. 2012 Jan;40(1):162-8. doi: 10.1097/CCM.0b013e31822d74a2.


Ventilator-associated pneumonia: role of positioning.

Li Bassi G, Torres A.

Curr Opin Crit Care. 2011 Feb;17(1):57-63. doi: 10.1097/MCC.0b013e3283428b31. Review.


Continuous lateral rotation therapy to prevent ventilator-associated pneumonia: the neglected effects of gravity on pathogenesis of ventilator-associated pneumonia.

Berra L, Cressoni M, Li Bassi G, Kolobow T, Panigada M, Zanella A; Gravity-VAP Network.

Crit Care Med. 2010 Mar;38(3):1018-9; author reply 1019. doi: 10.1097/CCM.0b013e3181cc40fc. No abstract available.


Perioperative hypothermia: the delicate balance between heat gain and heat loss.

Li Bassi G.

Minerva Anestesiol. 2008 Dec;74(12):683-5. No abstract available.


Antimicrobial-coated endotracheal tubes: an experimental study.

Berra L, Curto F, Li Bassi G, Laquerriere P, Pitts B, Baccarelli A, Kolobow T.

Intensive Care Med. 2008 Jun;34(6):1020-9. doi: 10.1007/s00134-008-1099-3. Epub 2008 Apr 17.


Following tracheal intubation, mucus flow is reversed in the semirecumbent position: possible role in the pathogenesis of ventilator-associated pneumonia.

Li Bassi G, Zanella A, Cressoni M, Stylianou M, Kolobow T.

Crit Care Med. 2008 Feb;36(2):518-25. doi: 10.1097/01.CCM.0000299741.32078.E9.


The effect of different volumes and temperatures of saline on the bladder pressure measurement in critically ill patients.

Chiumello D, Tallarini F, Chierichetti M, Polli F, Li Bassi G, Motta G, Azzari S, Carsenzola C, Gattinoni L.

Crit Care. 2007;11(4):R82.


Treatment of proximal humeral fractures with reverse prostheses in elderly patients.

Terragnoli F, Zattoni G, Damiani L, Cabrioli A, Li Bassi G.

J Orthop Traumatol. 2007 Jun;8(2):71-6. doi: 10.1007/s10195-007-0165-x. Epub 2007 Jun 8.


Silver-coated endotracheal tubes: is the bactericidal effect time limited?

Li Bassi G, Berra L, Kolobow T.

Crit Care Med. 2007 Mar;35(3):986; author reply 987. No abstract available.


A 72-hour study to test the efficacy and safety of the "Mucus Slurper" in mechanically ventilated sheep.

Li Bassi G, Curto F, Zanella A, Stylianou M, Kolobow T.

Crit Care Med. 2007 Mar;35(3):906-11.


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