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Items: 16

1.

Novel isatin-derived molecules activate p53 via interference with Mdm2 to promote apoptosis.

Fedorova O, Daks A, Petrova V, Petukhov A, Lezina L, Shuvalov O, Davidovich P, Kriger D, Lomert E, Tentler D, Kartsev V, Uyanik B, Tribulovich V, Demidov O, Melino G, Barlev NA.

Cell Cycle. 2018;17(15):1917-1930. doi: 10.1080/15384101.2018.1506664. Epub 2018 Sep 5.

PMID:
30109812
2.

CD40L/IL-4-stimulated CLL demonstrates variation in translational regulation of DNA damage response genes including ATM.

Lezina L, Spriggs RV, Beck D, Jones C, Dudek KM, Bzura A, Jones GDD, Packham G, Willis AE, Wagner SD.

Blood Adv. 2018 Aug 14;2(15):1869-1881. doi: 10.1182/bloodadvances.2017015560.

3.

Specific Drug Delivery to Cancer Cells with Double-Imprinted Nanoparticles against Epidermal Growth Factor Receptor.

Canfarotta F, Lezina L, Guerreiro A, Czulak J, Petukhov A, Daks A, Smolinska-Kempisty K, Poma A, Piletsky S, Barlev NA.

Nano Lett. 2018 Aug 8;18(8):4641-4646. doi: 10.1021/acs.nanolett.7b03206. Epub 2018 Jul 9.

PMID:
29969563
4.

Human EHMT2/G9a activates p53 through methylation-independent mechanism.

Rada M, Vasileva E, Lezina L, Marouco D, Antonov AV, Macip S, Melino G, Barlev NA.

Oncogene. 2017 Feb 16;36(7):922-932. doi: 10.1038/onc.2016.258. Epub 2016 Jul 25.

PMID:
27452519
5.

Synthetic Lethal Screen Demonstrates That a JAK2 Inhibitor Suppresses a BCL6-dependent IL10RA/JAK2/STAT3 Pathway in High Grade B-cell Lymphoma.

Beck D, Zobel J, Barber R, Evans S, Lezina L, Allchin RL, Blades M, Elliott R, Lord CJ, Ashworth A, Porter AC, Wagner SD.

J Biol Chem. 2016 Aug 5;291(32):16686-98. doi: 10.1074/jbc.M116.736868. Epub 2016 Jun 6.

6.

Extracellular vesicles released by CD40/IL-4-stimulated CLL cells confer altered functional properties to CD4+ T cells.

Smallwood DT, Apollonio B, Willimott S, Lezina L, Alharthi A, Ambrose AR, De Rossi G, Ramsay AG, Wagner SD.

Blood. 2016 Jul 28;128(4):542-52. doi: 10.1182/blood-2015-11-682377. Epub 2016 Apr 26.

7.

KMT Set7/9 affects genotoxic stress response via the Mdm2 axis.

Lezina L, Aksenova V, Fedorova O, Malikova D, Shuvalov O, Antonov AV, Tentler D, Garabadgiu AV, Melino G, Barlev NA.

Oncotarget. 2015 Sep 22;6(28):25843-55. doi: 10.18632/oncotarget.4584.

8.

Characterization of novel markers of senescence and their prognostic potential in cancer.

Althubiti M, Lezina L, Carrera S, Jukes-Jones R, Giblett SM, Antonov A, Barlev N, Saldanha GS, Pritchard CA, Cain K, Macip S.

Cell Death Dis. 2014 Nov 20;5:e1528. doi: 10.1038/cddis.2014.489.

9.

KMTase Set7/9 is a critical regulator of E2F1 activity upon genotoxic stress.

Lezina L, Aksenova V, Ivanova T, Purmessur N, Antonov AV, Tentler D, Fedorova O, Garabadgiu AV, Talianidis I, Melino G, Barlev NA.

Cell Death Differ. 2014 Dec;21(12):1889-99. doi: 10.1038/cdd.2014.108. Epub 2014 Aug 15.

10.

miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress.

Lezina L, Purmessur N, Antonov AV, Ivanova T, Karpova E, Krishan K, Ivan M, Aksenova V, Tentler D, Garabadgiu AV, Melino G, Barlev NA.

Cell Death Dis. 2013 Dec 12;4:e953. doi: 10.1038/cddis.2013.483.

11.

Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability.

Foster CT, Dovey OM, Lezina L, Luo JL, Gant TW, Barlev N, Bradley A, Cowley SM.

Mol Cell Biol. 2010 Oct;30(20):4851-63. doi: 10.1128/MCB.00521-10. Epub 2010 Aug 16.

12.

26S proteasome exhibits endoribonuclease activity controlled by extra-cellular stimuli.

Kulichkova VA, Tsimokha AS, Fedorova OA, Moiseeva TN, Bottril A, Lezina L, Gauze LN, Konstantinova IM, Mittenberg AG, Barlev NA.

Cell Cycle. 2010 Feb 15;9(4):840-9. Epub 2010 Mar 2.

PMID:
20139718
13.

DNA affinity purification of Epstein-Barr virus OriP-binding proteins.

Atanasiu C, Lezina L, Lieberman PM.

Methods Mol Biol. 2005;292:267-76.

PMID:
15507714
14.

Telomeric proteins regulate episomal maintenance of Epstein-Barr virus origin of plasmid replication.

Deng Z, Lezina L, Chen CJ, Shtivelband S, So W, Lieberman PM.

Mol Cell. 2002 Mar;9(3):493-503.

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