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Items: 1 to 50 of 681

1.

A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.

Zhang S, Sakuma M, Deora GS, Levy CW, Klausing A, Breda C, Read KD, Edlin CD, Ross BP, Wright Muelas M, Day PJ, O'Hagan S, Kell DB, Schwarcz R, Leys D, Heyes DJ, Giorgini F, Scrutton NS.

Commun Biol. 2019 Jul 24;2:271. doi: 10.1038/s42003-019-0520-5. eCollection 2019.

2.

Intravenous thrombolysis prior to mechanical thrombectomy in large vessel occlusions.

Katsanos AH, Malhotra K, Goyal N, Arthur A, Schellinger PD, Köhrmann M, Krogias C, Turc G, Magoufis G, Leys D, Ahmed N, Khatri P, Goyal M, Alexandrov AV, Tsivgoulis G.

Ann Neurol. 2019 Sep;86(3):395-406. doi: 10.1002/ana.25544. Epub 2019 Jul 22.

PMID:
31282044
3.

Editorial.

Leys D, Klijn K, Norrving B.

Eur Stroke J. 2019 Jun;4(2):99-100. doi: 10.1177/2396987319851741. Epub 2019 Jun 14. No abstract available.

4.

Editorial.

Leys D, Klijn K, Norrving B.

Eur Stroke J. 2018 Dec;3(4):307-308. doi: 10.1177/2396987318813246. Epub 2018 Nov 16. No abstract available.

5.

Access to mechanical thrombectomy for cerebral ischaemia: A population-based study in the North-of-France.

Leys D, Dequatre-Ponchelle N, Ferrigno M, Henon H, Mounier-Vehier F, Moulin S, Casolla B, Tortuyaux R, Chochoi M, Moreau C, Girard-Buttaz I, Pruvo JP, Goldstein P, Cordonnier C; STROKE NETWORK 59-62.

Rev Neurol (Paris). 2019 Jun 14. pii: S0035-3787(18)30934-2. doi: 10.1016/j.neurol.2018.12.010. [Epub ahead of print]

PMID:
31208814
6.

Antiplatelet Therapy After Noncardioembolic Stroke.

Greving JP, Diener HC, Reitsma JB, Bath PM, Csiba L, Hacke W, Kappelle LJ, Koudstaal PJ, Leys D, Mas JL, Sacco RL, Algra A.

Stroke. 2019 Jul;50(7):1812-1818. doi: 10.1161/STROKEAHA.118.024497. Epub 2019 Jun 10.

7.

Editorial.

Norrving B, Leys D, Klijn K.

Eur Stroke J. 2019 Mar;4(1):4-5. doi: 10.1177/2396987319834772. Epub 2019 Mar 6. No abstract available.

8.

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S; AFGen Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; INVENT Consortium; STARNET, Bis JC, Pastinen T, Ruusalepp A, Schadt EE, Koplev S, Björkegren JLM, Codoni V, Civelek M, Smith NL, Trégouët DA, Christophersen IE, Roselli C, Lubitz SA, Ellinor PT, Tai ES, Kooner JS, Kato N, He J, van der Harst P, Elliott P, Chambers JC, Takeuchi F, Johnson AD; BioBank Japan Cooperative Hospital Group; COMPASS Consortium; EPIC-CVD Consortium; EPIC-InterAct Consortium; International Stroke Genetics Consortium (ISGC); METASTROKE Consortium; Neurology Working Group of the CHARGE Consortium; NINDS Stroke Genetics Network (SiGN); UK Young Lacunar DNA Study; MEGASTROKE Consortium, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M.

Nat Genet. 2019 Jul;51(7):1192-1193. doi: 10.1038/s41588-019-0449-0.

PMID:
31160810
9.

The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry.

Marshall SA, Payne KAP, Fisher K, White MD, Ní Cheallaigh A, Balaikaite A, Rigby SEJ, Leys D.

Nat Commun. 2019 May 29;10(1):2357. doi: 10.1038/s41467-019-10220-1.

10.

Extending thrombolysis to 4·5-9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data.

Campbell BCV, Ma H, Ringleb PA, Parsons MW, Churilov L, Bendszus M, Levi CR, Hsu C, Kleinig TJ, Fatar M, Leys D, Molina C, Wijeratne T, Curtze S, Dewey HM, Barber PA, Butcher KS, De Silva DA, Bladin CF, Yassi N, Pfaff JAR, Sharma G, Bivard A, Desmond PM, Schwab S, Schellinger PD, Yan B, Mitchell PJ, Serena J, Toni D, Thijs V, Hacke W, Davis SM, Donnan GA; EXTEND, ECASS-4, and EPITHET Investigators.

Lancet. 2019 Jul 13;394(10193):139-147. doi: 10.1016/S0140-6736(19)31053-0. Epub 2019 May 22.

PMID:
31128925
11.

Heterologous production, reconstitution and EPR spectroscopic analysis of prFMN dependent enzymes.

Marshall SA, Payne KAP, Fisher K, Gahloth D, Bailey SS, Balaikaite A, Saaret A, Gostimskaya I, Aleku G, Huang H, Rigby SEJ, Procter D, Leys D.

Methods Enzymol. 2019;620:489-508. doi: 10.1016/bs.mie.2019.03.022. Epub 2019 Apr 11.

PMID:
31072499
12.

Enzymatic Carboxylation of 2-Furoic Acid Yields 2,5-Furandicarboxylic Acid (FDCA).

Payne KAP, Marshall SA, Fisher K, Cliff MJ, Cannas DM, Yan C, Heyes DJ, Parker DA, Larrosa I, Leys D.

ACS Catal. 2019 Apr 5;9(4):2854-2865. doi: 10.1021/acscatal.8b04862. Epub 2019 Feb 15.

13.

Five-Year Risk of Major Ischemic and Hemorrhagic Events After Intracerebral Hemorrhage.

Casolla B, Moulin S, Kyheng M, Hénon H, Labreuche J, Leys D, Bauters C, Cordonnier C.

Stroke. 2019 May;50(5):1100-1107. doi: 10.1161/STROKEAHA.118.024449.

PMID:
31009357
14.

Editorial.

Norrving B, Leys D, Klijn K.

Eur Stroke J. 2018 Sep;3(3):204-205. doi: 10.1177/2396987318795604. Epub 2018 Aug 30. No abstract available.

15.

Editorial.

Leys D, Norrving B.

Eur Stroke J. 2018 Jun;3(2):99-100. doi: 10.1177/2396987318772409. Epub 2018 Apr 30. No abstract available.

16.

Stroke in 2018: new progress and new challenges.

Norrving B, Leys D.

Eur Stroke J. 2018 Mar;3(1):4. doi: 10.1177/2396987318760162. Epub 2018 Feb 20. No abstract available.

17.

Extending the time window for intravenous thrombolysis in acute ischemic stroke using magnetic resonance imaging-based patient selection.

Ringleb P, Bendszus M, Bluhmki E, Donnan G, Eschenfelder C, Fatar M, Kessler C, Molina C, Leys D, Muddegowda G, Poli S, Schellinger P, Schwab S, Serena J, Toni D, Wahlgren N, Hacke W; ECASS-4 study group.

Int J Stroke. 2019 Apr 4:1747493019840938. doi: 10.1177/1747493019840938. [Epub ahead of print]

PMID:
30947642
18.

Triple and quadruple cervical artery dissections: a systematic review of individual patient data.

Guglielmi V, Visser J, Arnold M, Sarikaya H, van den Berg R, Nederkoorn PJ, Leys D, Calvet D, Kloss M, Pezzini A, Tatlisumak T, Schilling S, Debette S, Coutinho JM.

J Neurol. 2019 Jun;266(6):1383-1388. doi: 10.1007/s00415-019-09269-1. Epub 2019 Mar 23.

19.

Preadmission use of benzodiazepines and stroke outcomes: the Biostroke prospective cohort study.

Colin O, Labreuche J, Deguil J, Mendyk AM, Deken V, Cordonnier C, Deplanque D, Leys D, Bordet R.

BMJ Open. 2019 Jan 15;9(1):e022720. doi: 10.1136/bmjopen-2018-022720.

20.

Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs.

Jeffreys LN, Poddar H, Golovanova M, Levy CW, Girvan HM, McLean KJ, Voice MW, Leys D, Munro AW.

Sci Rep. 2019 Feb 7;9(1):1577. doi: 10.1038/s41598-018-37330-y.

21.

Genetic Imbalance Is Associated With Functional Outcome After Ischemic Stroke.

Pfeiffer D, Chen B, Schlicht K, Ginsbach P, Abboud S, Bersano A, Bevan S, Brandt T, Caso V, Debette S, Erhart P, Freitag-Wolf S, Giacalone G, Grau AJ, Hayani E, Jern C, Jiménez-Conde J, Kloss M, Krawczak M, Lee JM, Lemmens R, Leys D, Lichy C, Maguire JM, Martin JJ, Metso AJ, Metso TM, Mitchell BD, Pezzini A, Rosand J, Rost NS, Stenman M, Tatlisumak T, Thijs V, Touzé E, Traenka C, Werner I, Woo D, Del Zotto E, Engelter ST, Kittner SJ, Cole JW, Grond-Ginsbach C, Lyrer PA, Lindgren A; CADISP; GISCOME; SiGN studies; and ISGC.

Stroke. 2019 Feb;50(2):298-304. doi: 10.1161/STROKEAHA.118.021856.

PMID:
30661490
22.

Characterization of a Putrescine Transaminase From Pseudomonas putida and its Application to the Synthesis of Benzylamine Derivatives.

Galman JL, Gahloth D, Parmeggiani F, Slabu I, Leys D, Turner NJ.

Front Bioeng Biotechnol. 2018 Dec 21;6:205. doi: 10.3389/fbioe.2018.00205. eCollection 2018.

23.

Editorial: The changing profile of cerebrovascular diseases.

Leys D.

Curr Opin Neurol. 2019 Feb;32(1):1-2. doi: 10.1097/WCO.0000000000000648. No abstract available.

PMID:
30516644
24.

Aging and cerebrovascular lesions in pure and in mixed neurodegenerative and vascular dementia brains: a neuropathological study.

De Reuck J, Maurage CA, Deramecourt V, Pasquier F, Cordonnier C, Leys D, Bordet R.

Folia Neuropathol. 2018;56(2):81-87. doi: 10.5114/fn.2018.76610.

25.

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.

Cole JW, Xu H, Ryan K, Jaworek T, Dueker N, McArdle P, Gaynor B, Cheng YC, O'Connell J, Bevan S, Malik R, Ahmed NU, Amouyel P, Anjum S, Bis JC, Crosslin D, Danesh J, Engelter ST, Fornage M, Frossard P, Gieger C, Giese AK, Grond-Ginsbach C, Ho WK, Holliday E, Hopewell J, Hussain M, Iqbal W, Jabeen S, Jannes J, Kamal A, Kamatani Y, Kanse S, Kloss M, Lathrop M, Leys D, Lindgren A, Longstreth WT Jr, Mahmood K, Meisinger C, Metso TM, Mosley T Jr, Müller-Nurasyid M, Norrving B, Parati E, Peters A, Pezzini A, Quereshi I, Rasheed A, Rauf A, Salam T, Shen J, Słowik A, Stanne T, Strauch K, Tatlisumak T, Thijs VN, Tiedt S, Traylor M, Waldenberger M, Walters M, Zhao W, Boncoraglio G, Debette S, Jern C, Levi C, Markus H, Meschia J, Rolfs A, Rothwell P, Saleheen D, Seshadri S, Sharma P, Sudlow C, Worrall B; METASTROKE Consortium of the ISGC; WTCCC-2 Consortium, Stine OC, Kittner SJ, Mitchell BD.

PLoS One. 2018 Nov 1;13(11):e0206554. doi: 10.1371/journal.pone.0206554. eCollection 2018.

26.

Biological and imaging predictors of cognitive impairment after stroke: a systematic review.

Casolla B, Caparros F, Cordonnier C, Bombois S, Hénon H, Bordet R, Orzi F, Leys D.

J Neurol. 2018 Oct 22. doi: 10.1007/s00415-018-9089-z. [Epub ahead of print] Review.

PMID:
30350168
27.

Terminal Alkenes from Acrylic Acid Derivatives via Non-Oxidative Enzymatic Decarboxylation by Ferulic Acid Decarboxylases.

Aleku GA, Prause C, Bradshaw-Allen RT, Plasch K, Glueck SM, Bailey SS, Payne KAP, Parker DA, Faber K, Leys D.

ChemCatChem. 2018 Sep 7;10(17):3736-3745. doi: 10.1002/cctc.201800643. Epub 2018 Jul 17.

28.

Flavin metamorphosis: cofactor transformation through prenylation.

Leys D.

Curr Opin Chem Biol. 2018 Dec;47:117-125. doi: 10.1016/j.cbpa.2018.09.024. Epub 2018 Oct 13. Review.

29.

Neutrophils in tPA-induced hemorrhagic transformations: Main culprit, accomplice or innocent bystander?

Ouk T, Potey C, Maestrini I, Petrault M, Mendyk AM, Leys D, Bordet R, Gautier S.

Pharmacol Ther. 2019 Feb;194:73-83. doi: 10.1016/j.pharmthera.2018.09.005. Epub 2018 Sep 18. Review.

PMID:
30240634
30.

Stroke mimics and chameleons.

Moulin S, Leys D.

Curr Opin Neurol. 2019 Feb;32(1):54-59. doi: 10.1097/WCO.0000000000000620. Review.

PMID:
30239360
31.

Cohort profile: Thrombolysis in Ischemic Stroke Patients (TRISP): a multicentre research collaboration.

Scheitz JF, Gensicke H, Zinkstok SM, Curtze S, Arnold M, Hametner C, Pezzini A, Turc G, Zini A, Padjen V, Wegener S, Nordanstig A, Kellert L, Kägi G, Bejot Y, Michel P, Leys D, Nolte CH, Nederkoorn PJ, Engelter ST; TRISP collaboration.

BMJ Open. 2018 Sep 17;8(9):e023265. doi: 10.1136/bmjopen-2018-023265.

32.

Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus.

Girvan HM, Poddar H, McLean KJ, Nelson DR, Hollywood KA, Levy CW, Leys D, Munro AW.

J Inorg Biochem. 2018 Nov;188:18-28. doi: 10.1016/j.jinorgbio.2018.08.002. Epub 2018 Aug 3.

33.

Determinants and outcome of multiple and early recurrent cervical artery dissections.

Compter A, Schilling S, Vaineau CJ, Goeggel-Simonetti B, Metso TM, Southerland A, Pezzini A, Kloss M, Touzé E, Worrall BB, Thijs V, Bejot Y, Reiner P, Grond-Ginsbach C, Bersano A, Brandt T, Caso V, Lyrer PA, Traenka C, Lichy C, Martin JJ, Leys D, Sarikaya H, Baumgartner RW, Jung S, Fischer U, Engelter ST, Dallongeville J, Chabriat H, Tatlisumak T, Bousser MG, Arnold M, Debette S; CADISP-plus Consortium.

Neurology. 2018 Aug 21;91(8):e769-e780. doi: 10.1212/WNL.0000000000006037. Epub 2018 Aug 1.

PMID:
30068628
34.

What now for embolic stroke of undetermined source?

Leys D, Moulin S.

Nat Rev Neurol. 2018 Sep;14(9):512-513. doi: 10.1038/s41582-018-0046-3. No abstract available.

PMID:
29995836
35.

Transatlantic Differences in Management of Carotid Stenosis: BRIDGing the Gap in StrokE Management (BRIDGE) Project.

Balucani C, Arnedo V, Weedon J, Leys D, Mas JL, Brown M, Grotta JC, Gonzales NR, Hacke W, Brott T, Levine SR.

Neurohospitalist. 2018 Jul;8(3):113-123. doi: 10.1177/1941874417747772. Epub 2018 Jan 17.

36.

Cortical superficial siderosis: A prospective observational cohort study.

Moulin S, Casolla B, Kuchcinski G, Boulouis G, Rossi C, Hénon H, Leys D, Cordonnier C.

Neurology. 2018 Jul 10;91(2):e132-e138. doi: 10.1212/WNL.0000000000005778. Epub 2018 Jun 8.

PMID:
29884737
37.

Intravenous Recombinant Tissue-Type Plasminogen Activator: Influence on Outcome in Anterior Circulation Ischemic Stroke Treated by Mechanical Thrombectomy.

Ferrigno M, Bricout N, Leys D, Estrade L, Cordonnier C, Personnic T, Kyheng M, Henon H.

Stroke. 2018 Jun;49(6):1377-1385. doi: 10.1161/STROKEAHA.118.020490. Epub 2018 May 10.

PMID:
29748424
38.

NADPH-Driven Organohalide Reduction by a Nonrespiratory Reductive Dehalogenase.

Collins FA, Fisher K, Payne KAP, Gaytan Mondragon S, Rigby SEJ, Leys D.

Biochemistry. 2018 Jun 26;57(25):3493-3502. doi: 10.1021/acs.biochem.8b00255. Epub 2018 Jun 13.

PMID:
29630828
39.

Influence of on-going treatment with angiotensin-converting enzyme inhibitor or angiotensin receptor blocker on the outcome of patients treated with intravenous rt-PA for ischemic stroke.

Gilliot S, Sibon I, Mas JL, Moulin T, Béjot Y, Cordonnier C, Giroud M, Odou P, Bordet R, Vivien D, Leys D; OPHELIE Investigators.

J Neurol. 2018 May;265(5):1166-1173. doi: 10.1007/s00415-018-8827-6. Epub 2018 Mar 16.

PMID:
29549467
40.

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S; AFGen Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; INVENT Consortium; STARNET, Bis JC, Pastinen T, Ruusalepp A, Schadt EE, Koplev S, Björkegren JLM, Codoni V, Civelek M, Smith NL, Trégouët DA, Christophersen IE, Roselli C, Lubitz SA, Ellinor PT, Tai ES, Kooner JS, Kato N, He J, van der Harst P, Elliott P, Chambers JC, Takeuchi F, Johnson AD; BioBank Japan Cooperative Hospital Group; COMPASS Consortium; EPIC-CVD Consortium; EPIC-InterAct Consortium; International Stroke Genetics Consortium (ISGC); METASTROKE Consortium; Neurology Working Group of the CHARGE Consortium; NINDS Stroke Genetics Network (SiGN); UK Young Lacunar DNA Study; MEGASTROKE Consortium, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M.

Nat Genet. 2018 Apr;50(4):524-537. doi: 10.1038/s41588-018-0058-3. Epub 2018 Mar 12. Erratum in: Nat Genet. 2019 Jul;51(7):1192-1193.

41.

University education and cervical artery dissection.

Kellert L, Grau A, Pezzini A, Debette S, Leys D, Caso V, Thijs VN, Bersano A, Touzé E, Tatlisumak T, Traenka C, Lyrer PA, Engelter ST, Metso TM, Grond-Ginsbach C, Kloss M; Cervical Artery Dissection and Ischemic Stroke Patients (CADISP)-Study Group.

J Neurol. 2018 May;265(5):1065-1070. doi: 10.1007/s00415-018-8798-7. Epub 2018 Feb 24.

PMID:
29478223
42.

Controlled Education of patients after Stroke (CEOPS)- nurse-led multimodal and long-term interventional program involving a patient's caregiver to optimize secondary prevention of stroke: study protocol for a randomized controlled trial.

Mendyk AM, Duhamel A, Bejot Y, Leys D, Derex L, Dereeper O, Detante O, Garcia PY, Godefroy O, Montoro FM, Neau JP, Richard S, Rosolacci T, Sibon I, Sablot D, Timsit S, Zuber M, Cordonnier C, Bordet R; on the behalf of Strokavenir network.

Trials. 2018 Feb 22;19(1):137. doi: 10.1186/s13063-018-2483-0.

43.

Intravenous thrombolysis and platelet count.

Gensicke H, Al Sultan AS, Strbian D, Hametner C, Zinkstok SM, Moulin S, Bill O, Zini A, Padjen V, Kägi G, Pezzini A, Seiffge DJ, Traenka C, Räty S, Amiri H, Zonneveld TP, Lachenmeier R, Polymeris A, Roos YB, Gumbinger C, Jovanovic DR, Curtze S, Sibolt G, Vandelli L, Ringleb PA, Leys D, Cordonnier C, Michel P, Lyrer PA, Peters N, Tatlisumak T, Nederkoorn PJ, Engelter ST; Thrombolysis in Stroke Patients (TRISP) Collaborators.

Neurology. 2018 Feb 20;90(8):e690-e697. doi: 10.1212/WNL.0000000000004982. Epub 2018 Jan 24. Erratum in: Neurology. 2018 Oct 30;91(18):852.

PMID:
29367438
44.

Heterologous Production and Purification of a Functional Chloroform Reductive Dehalogenase.

Jugder BE, Payne KAP, Fisher K, Bohl S, Lebhar H, Manefield M, Lee M, Leys D, Marquis CP.

ACS Chem Biol. 2018 Mar 16;13(3):548-552. doi: 10.1021/acschembio.7b00846. Epub 2018 Jan 25.

PMID:
29363941
45.

The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis.

Bailey SS, Payne KAP, Fisher K, Marshall SA, Cliff MJ, Spiess R, Parker DA, Rigby SEJ, Leys D.

J Biol Chem. 2018 Feb 16;293(7):2272-2287. doi: 10.1074/jbc.RA117.000881. Epub 2017 Dec 19.

46.

Non-office-hours admission affects intravenous thrombolysis treatment times and clinical outcome.

Zonneveld TP, Curtze S, Zinkstok SM, Gensicke H, Moulin S, Scheitz JF, Seiffge DJ, Hametner C, Heldner MR, Traenka C, Erdur H, Baharoglu I, Martinez-Majander N, Pezzini A, Zini A, Padjen V, Correia PN, Strbian D, Michel P, Béjot Y, Arnold M, Leys D, Ringleb PA, Tatlisumak T, Nolte CH, Engelter ST, Nederkoorn PJ; TRISP collaborators.

J Neurol Neurosurg Psychiatry. 2018 Sep;89(9):1005-1007. doi: 10.1136/jnnp-2017-316791. Epub 2017 Oct 25. No abstract available.

PMID:
29070647
47.

Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes.

Weise NJ, Ahmed ST, Parmeggiani F, Galman JL, Dunstan MS, Charnock SJ, Leys D, Turner NJ.

Sci Rep. 2017 Oct 20;7(1):13691. doi: 10.1038/s41598-017-13990-0.

48.

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