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Items: 1 to 50 of 54

1.

Ammonium salts are a reservoir of nitrogen on a cometary nucleus and possibly on some asteroids.

Poch O, Istiqomah I, Quirico E, Beck P, Schmitt B, Theulé P, Faure A, Hily-Blant P, Bonal L, Raponi A, Ciarniello M, Rousseau B, Potin S, Brissaud O, Flandinet L, Filacchione G, Pommerol A, Thomas N, Kappel D, Mennella V, Moroz L, Vinogradoff V, Arnold G, Erard S, Bockelée-Morvan D, Leyrat C, Capaccioni F, De Sanctis MC, Longobardo A, Mancarella F, Palomba E, Tosi F.

Science. 2020 Mar 13;367(6483). pii: eaaw7462. doi: 10.1126/science.aaw7462.

PMID:
32165559
2.

Propensity scores using missingness pattern information: a practical guide.

Blake HA, Leyrat C, Mansfield KE, Seaman S, Tomlinson LA, Carpenter J, Williamson EJ.

Stat Med. 2020 Feb 27. doi: 10.1002/sim.8503. [Epub ahead of print]

PMID:
32103533
3.

Estimating treatment effects with partially observed covariates using outcome regression with missing indicators.

Blake HA, Leyrat C, Mansfield KE, Tomlinson LA, Carpenter J, Williamson EJ.

Biom J. 2020 Mar;62(2):428-443. doi: 10.1002/bimj.201900041. Epub 2020 Jan 29.

PMID:
31994239
4.

Proactive case detection of common childhood illnesses by community health workers: a systematic review.

Whidden C, Thwing J, Gutman J, Wohl E, Leyrat C, Kayentao K, Johnson AD, Greenwood B, Chandramohan D.

BMJ Glob Health. 2019 Dec 15;4(6):e001799. doi: 10.1136/bmjgh-2019-001799. eCollection 2019.

5.

The LC8-RavP ensemble Structure Evinces A Role for LC8 in Regulating Lyssavirus Polymerase Functionality.

Jespersen NE, Leyrat C, Gérard FC, Bourhis JM, Blondel D, Jamin M, Barbar E.

J Mol Biol. 2019 Dec 6;431(24):4959-4977. doi: 10.1016/j.jmb.2019.10.011. Epub 2019 Oct 18.

PMID:
31634467
6.
7.

Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.

Vasiliauskaité-Brooks I, Healey RD, Rochaix P, Saint-Paul J, Sounier R, Grison C, Waltrich-Augusto T, Fortier M, Hoh F, Saied EM, Arenz C, Basu S, Leyrat C, Granier S.

Nat Commun. 2018 Dec 21;9(1):5437. doi: 10.1038/s41467-018-07864-w.

8.

Intervention effect estimates in cluster randomized versus individually randomized trials: a meta-epidemiological study.

Leyrat C, Caille A, Eldridge S, Kerry S, Dechartres A, Giraudeau B.

Int J Epidemiol. 2019 Apr 1;48(2):609-619. doi: 10.1093/ije/dyy229.

9.

Response to: How to design and analyse cluster randomized trials with a small number of clusters? Comment on Leyrat et al.

Leyrat C, Morgan KE, Leurent B, Kahan BC.

Int J Epidemiol. 2018 Jun 1;47(3):1001-1002. doi: 10.1093/ije/dyy062. No abstract available.

10.

Cluster randomized trials with a small number of clusters: which analyses should be used?

Leyrat C, Morgan KE, Leurent B, Kahan BC.

Int J Epidemiol. 2018 Jun 1;47(3):1012. doi: 10.1093/ije/dyy057. No abstract available.

PMID:
29596636
11.

Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study.

Crellin E, Mansfield KE, Leyrat C, Nitsch D, Douglas IJ, Root A, Williamson E, Smeeth L, Tomlinson LA.

BMJ. 2018 Feb 9;360:k341. doi: 10.1136/bmj.k341.

12.

Quality of reporting of pilot and feasibility cluster randomised trials: a systematic review.

Chan CL, Leyrat C, Eldridge SM.

BMJ Open. 2017 Nov 8;7(11):e016970. doi: 10.1136/bmjopen-2017-016970. Review.

13.

Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering.

Renner M, Paesen GC, Grison CM, Granier S, Grimes JM, Leyrat C.

Sci Rep. 2017 Nov 1;7(1):14865. doi: 10.1038/s41598-017-14448-z.

14.

Cluster randomized trials with a small number of clusters: which analyses should be used?

Leyrat C, Morgan KE, Leurent B, Kahan BC.

Int J Epidemiol. 2018 Feb 1;47(1):321-331. doi: 10.1093/ije/dyx169.

15.

Propensity score analysis with partially observed covariates: How should multiple imputation be used?

Leyrat C, Seaman SR, White IR, Douglas I, Smeeth L, Kim J, Resche-Rigon M, Carpenter JR, Williamson EJ.

Stat Methods Med Res. 2019 Jan;28(1):3-19. doi: 10.1177/0962280217713032. Epub 2017 Jun 2.

16.

Structural insights into adiponectin receptors suggest ceramidase activity.

Vasiliauskaité-Brooks I, Sounier R, Rochaix P, Bellot G, Fortier M, Hoh F, De Colibus L, Bechara C, Saied EM, Arenz C, Leyrat C, Granier S.

Nature. 2017 Apr 6;544(7648):120-123. doi: 10.1038/nature21714. Epub 2017 Mar 22.

17.

Seasonal exposure of carbon dioxide ice on the nucleus of comet 67P/Churyumov-Gerasimenko.

Filacchione G, Raponi A, Capaccioni F, Ciarniello M, Tosi F, Capria MT, De Sanctis MC, Migliorini A, Piccioni G, Cerroni P, Barucci MA, Fornasier S, Schmitt B, Quirico E, Erard S, Bockelee-Morvan D, Leyrat C, Arnold G, Mennella V, Ammannito E, Bellucci G, Benkhoff J, Bibring JP, Blanco A, Blecka MI, Carlson R, Carsenty U, Colangeli L, Combes M, Combi M, Crovisier J, Drossart P, Encrenaz T, Federico C, Fink U, Fonti S, Fulchignoni M, Ip WH, Irwin P, Jaumann R, Kuehrt E, Langevin Y, Magni G, McCord T, Moroz L, Mottola S, Palomba E, Schade U, Stephan K, Taylor F, Tiphene D, Tozzi GP, Beck P, Biver N, Bonal L, Combe JP, Despan D, Flamini E, Formisano M, Frigeri A, Grassi D, Gudipati MS, Kappel D, Longobardo A, Mancarella F, Markus K, Merlin F, Orosei R, Rinaldi G, Cartacci M, Cicchetti A, Hello Y, Henry F, Jacquinod S, Reess JM, Noschese R, Politi R, Peter G.

Science. 2016 Dec 23;354(6319):1563-1566. doi: 10.1126/science.aag3161. Epub 2016 Nov 17.

PMID:
27856846
18.

Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs.

Stoeber M, Schellenberger P, Siebert CA, Leyrat C, Helenius A, Grünewald K.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8069-E8078. Epub 2016 Nov 10.

19.

Increased risk of type I errors in cluster randomised trials with small or medium numbers of clusters: a review, reanalysis, and simulation study.

Kahan BC, Forbes G, Ali Y, Jairath V, Bremner S, Harhay MO, Hooper R, Wright N, Eldridge SM, Leyrat C.

Trials. 2016 Sep 6;17(1):438. doi: 10.1186/s13063-016-1571-2.

20.

Timeline cluster: a graphical tool to identify risk of bias in cluster randomised trials.

Caille A, Kerry S, Tavernier E, Leyrat C, Eldridge S, Giraudeau B.

BMJ. 2016 Aug 16;354:i4291. doi: 10.1136/bmj.i4291. No abstract available.

21.

Ensemble Structure of the Highly Flexible Complex Formed between Vesicular Stomatitis Virus Unassembled Nucleoprotein and its Phosphoprotein Chaperone.

Yabukarski F, Leyrat C, Martinez N, Communie G, Ivanov I, Ribeiro EA Jr, Buisson M, Gerard FC, Bourhis JM, Jensen MR, Bernadó P, Blackledge M, Jamin M.

J Mol Biol. 2016 Jul 3;428(13):2671-94. doi: 10.1016/j.jmb.2016.04.010. Epub 2016 Apr 21.

PMID:
27107640
22.

Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein.

Renner M, Bertinelli M, Leyrat C, Paesen GC, Saraiva de Oliveira LF, Huiskonen JT, Grimes JM.

Elife. 2016 Feb 15;5:e12627. doi: 10.7554/eLife.12627.

23.

Propensity score to detect baseline imbalance in cluster randomized trials: the role of the c-statistic.

Leyrat C, Caille A, Foucher Y, Giraudeau B.

BMC Med Res Methodol. 2016 Jan 22;16:9. doi: 10.1186/s12874-015-0100-4.

24.

Exposed water ice on the nucleus of comet 67P/Churyumov-Gerasimenko.

Filacchione G, De Sanctis MC, Capaccioni F, Raponi A, Tosi F, Ciarniello M, Cerroni P, Piccioni G, Capria MT, Palomba E, Bellucci G, Erard S, Bockelee-Morvan D, Leyrat C, Arnold G, Barucci MA, Fulchignoni M, Schmitt B, Quirico E, Jaumann R, Stephan K, Longobardo A, Mennella V, Migliorini A, Ammannito E, Benkhoff J, Bibring JP, Blanco A, Blecka MI, Carlson R, Carsenty U, Colangeli L, Combes M, Combi M, Crovisier J, Drossart P, Encrenaz T, Federico C, Fink U, Fonti S, Ip WH, Irwin P, Kuehrt E, Langevin Y, Magni G, McCord T, Moroz L, Mottola S, Orofino V, Schade U, Taylor F, Tiphene D, Tozzi GP, Beck P, Biver N, Bonal L, Combe JP, Despan D, Flamini E, Formisano M, Fornasier S, Frigeri A, Grassi D, Gudipati MS, Kappel D, Mancarella F, Markus K, Merlin F, Orosei R, Rinaldi G, Cartacci M, Cicchetti A, Giuppi S, Hello Y, Henry F, Jacquinod S, Reess JM, Noschese R, Politi R, Peter G.

Nature. 2016 Jan 21;529(7586):368-72. doi: 10.1038/nature16190. Epub 2016 Jan 13.

PMID:
26760209
25.

The diurnal cycle of water ice on comet 67P/Churyumov-Gerasimenko.

De Sanctis MC, Capaccioni F, Ciarniello M, Filacchione G, Formisano M, Mottola S, Raponi A, Tosi F, Bockelée-Morvan D, Erard S, Leyrat C, Schmitt B, Ammannito E, Arnold G, Barucci MA, Combi M, Capria MT, Cerroni P, Ip WH, Kuehrt E, McCord TB, Palomba E, Beck P, Quirico E; VIRTIS Team.

Nature. 2015 Sep 24;525(7570):500-3. doi: 10.1038/nature14869.

PMID:
26399830
26.

Performance of principal scores to estimate the marginal compliers causal effect of an intervention.

Porcher R, Leyrat C, Baron G, Giraudeau B, Boutron I.

Stat Med. 2016 Feb 28;35(5):752-67. doi: 10.1002/sim.6735. Epub 2015 Sep 17.

PMID:
26381261
27.

Calcium-controlled conformational choreography in the N-terminal half of adseverin.

Chumnarnsilpa S, Robinson RC, Grimes JM, Leyrat C.

Nat Commun. 2015 Sep 14;6:8254. doi: 10.1038/ncomms9254.

28.

Large heterogeneities in comet 67P as revealed by active pits from sinkhole collapse.

Vincent JB, Bodewits D, Besse S, Sierks H, Barbieri C, Lamy P, Rodrigo R, Koschny D, Rickman H, Keller HU, Agarwal J, A'Hearn MF, Auger AT, Barucci MA, Bertaux JL, Bertini I, Capanna C, Cremonese G, Da Deppo V, Davidsson B, Debei S, De Cecco M, El-Maarry MR, Ferri F, Fornasier S, Fulle M, Gaskell R, Giacomini L, Groussin O, Guilbert-Lepoutre A, Gutierrez-Marques P, Gutiérrez PJ, Güttler C, Hoekzema N, Höfner S, Hviid SF, Ip WH, Jorda L, Knollenberg J, Kovacs G, Kramm R, Kührt E, Küppers M, La Forgia F, Lara LM, Lazzarin M, Lee V, Leyrat C, Lin ZY, Lopez Moreno JJ, Lowry S, Magrin S, Maquet L, Marchi S, Marzari F, Massironi M, Michalik H, Moissl R, Mottola S, Naletto G, Oklay N, Pajola M, Preusker F, Scholten F, Thomas N, Toth I, Tubiana C.

Nature. 2015 Jul 2;523(7558):63-6. doi: 10.1038/nature14564.

PMID:
26135448
29.

Cometary science. On the nucleus structure and activity of comet 67P/Churyumov-Gerasimenko.

Sierks H, Barbieri C, Lamy PL, Rodrigo R, Koschny D, Rickman H, Keller HU, Agarwal J, A'Hearn MF, Angrilli F, Auger AT, Barucci MA, Bertaux JL, Bertini I, Besse S, Bodewits D, Capanna C, Cremonese G, Da Deppo V, Davidsson B, Debei S, De Cecco M, Ferri F, Fornasier S, Fulle M, Gaskell R, Giacomini L, Groussin O, Gutierrez-Marques P, Gutiérrez PJ, Güttler C, Hoekzema N, Hviid SF, Ip WH, Jorda L, Knollenberg J, Kovacs G, Kramm JR, Kührt E, Küppers M, La Forgia F, Lara LM, Lazzarin M, Leyrat C, Lopez Moreno JJ, Magrin S, Marchi S, Marzari F, Massironi M, Michalik H, Moissl R, Mottola S, Naletto G, Oklay N, Pajola M, Pertile M, Preusker F, Sabau L, Scholten F, Snodgrass C, Thomas N, Tubiana C, Vincent JB, Wenzel KP, Zaccariotto M, Pätzold M.

Science. 2015 Jan 23;347(6220):aaa1044. doi: 10.1126/science.aaa1044.

30.

Cometary science. Subsurface properties and early activity of comet 67P/Churyumov-Gerasimenko.

Gulkis S, Allen M, von Allmen P, Beaudin G, Biver N, Bockelée-Morvan D, Choukroun M, Crovisier J, Davidsson BJ, Encrenaz P, Encrenaz T, Frerking M, Hartogh P, Hofstadter M, Ip WH, Janssen M, Jarchow C, Keihm S, Lee S, Lellouch E, Leyrat C, Rezac L, Schloerb FP, Spilker T.

Science. 2015 Jan 23;347(6220):aaa0709. doi: 10.1126/science.aaa0709.

31.

Cometary science. The organic-rich surface of comet 67P/Churyumov-Gerasimenko as seen by VIRTIS/Rosetta.

Capaccioni F, Coradini A, Filacchione G, Erard S, Arnold G, Drossart P, De Sanctis MC, Bockelee-Morvan D, Capria MT, Tosi F, Leyrat C, Schmitt B, Quirico E, Cerroni P, Mennella V, Raponi A, Ciarniello M, McCord T, Moroz L, Palomba E, Ammannito E, Barucci MA, Bellucci G, Benkhoff J, Bibring JP, Blanco A, Blecka M, Carlson R, Carsenty U, Colangeli L, Combes M, Combi M, Crovisier J, Encrenaz T, Federico C, Fink U, Fonti S, Ip WH, Irwin P, Jaumann R, Kuehrt E, Langevin Y, Magni G, Mottola S, Orofino V, Palumbo P, Piccioni G, Schade U, Taylor F, Tiphene D, Tozzi GP, Beck P, Biver N, Bonal L, Combe JP, Despan D, Flamini E, Fornasier S, Frigeri A, Grassi D, Gudipati M, Longobardo A, Markus K, Merlin F, Orosei R, Rinaldi G, Stephan K, Cartacci M, Cicchetti A, Giuppi S, Hello Y, Henry F, Jacquinod S, Noschese R, Peter G, Politi R, Reess JM, Semery A.

Science. 2015 Jan 23;347(6220):aaa0628. doi: 10.1126/science.aaa0628.

32.

Structural basis of thymosin-β4/profilin exchange leading to actin filament polymerization.

Xue B, Leyrat C, Grimes JM, Robinson RC.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4596-605. doi: 10.1073/pnas.1412271111. Epub 2014 Oct 13.

33.

Structural insights into the human metapneumovirus glycoprotein ectodomain.

Leyrat C, Paesen GC, Charleston J, Renner M, Grimes JM.

J Virol. 2014 Oct;88(19):11611-6. doi: 10.1128/JVI.01726-14. Epub 2014 Jul 16.

34.

Drastic changes in conformational dynamics of the antiterminator M2-1 regulate transcription efficiency in Pneumovirinae.

Leyrat C, Renner M, Harlos K, Huiskonen JT, Grimes JM.

Elife. 2014 May 19;3:e02674. doi: 10.7554/eLife.02674.

35.

Propensity score methods for estimating relative risks in cluster randomized trials with low-incidence binary outcomes and selection bias.

Leyrat C, Caille A, Donner A, Giraudeau B.

Stat Med. 2014 Sep 10;33(20):3556-75. doi: 10.1002/sim.6185. Epub 2014 Apr 27.

PMID:
24771662
36.

A comparison of imputation strategies in cluster randomized trials with missing binary outcomes.

Caille A, Leyrat C, Giraudeau B.

Stat Methods Med Res. 2016 Dec;25(6):2650-2669. Epub 2014 Apr 7.

PMID:
24713160
37.

[Cluster randomised trials].

Caille A, Leyrat C, Giraudeau B.

Ann Dermatol Venereol. 2014 Feb;141(2):144-6. doi: 10.1016/j.annder.2013.07.024. Epub 2013 Nov 22. Review. French. No abstract available.

PMID:
24507210
38.

Structure and self-assembly of the calcium binding matrix protein of human metapneumovirus.

Leyrat C, Renner M, Harlos K, Huiskonen JT, Grimes JM.

Structure. 2014 Jan 7;22(1):136-48. doi: 10.1016/j.str.2013.10.013. Epub 2013 Dec 5.

39.

Solution and crystallographic structures of the central region of the phosphoprotein from human metapneumovirus.

Leyrat C, Renner M, Harlos K, Grimes JM.

PLoS One. 2013 Nov 4;8(11):e80371. doi: 10.1371/journal.pone.0080371. eCollection 2013.

40.

Structure of the C-terminal domain of lettuce necrotic yellows virus phosphoprotein.

Martinez N, Ribeiro EA Jr, Leyrat C, Tarbouriech N, Ruigrok RW, Jamin M.

J Virol. 2013 Sep;87(17):9569-78. doi: 10.1128/JVI.00999-13. Epub 2013 Jun 19.

41.

Propensity scores used for analysis of cluster randomized trials with selection bias: a simulation study.

Leyrat C, Caille A, Donner A, Giraudeau B.

Stat Med. 2013 Aug 30;32(19):3357-72. doi: 10.1002/sim.5795. Epub 2013 Mar 31.

PMID:
23553813
42.

Structure of the full-length HCV IRES in solution.

Pérard J, Leyrat C, Baudin F, Drouet E, Jamin M.

Nat Commun. 2013;4:1612. doi: 10.1038/ncomms2611.

PMID:
23511476
43.

Ensemble structure of the modular and flexible full-length vesicular stomatitis virus phosphoprotein.

Leyrat C, Schneider R, Ribeiro EA Jr, Yabukarski F, Yao M, Gérard FC, Jensen MR, Ruigrok RW, Blackledge M, Jamin M.

J Mol Biol. 2012 Oct 19;423(2):182-97. doi: 10.1016/j.jmb.2012.07.003. Epub 2012 Jul 9.

PMID:
22789567
44.

Dichotomizing a continuous outcome in cluster randomized trials: impact on power.

Caille A, Leyrat C, Giraudeau B.

Stat Med. 2012 Oct 30;31(24):2822-32. doi: 10.1002/sim.5409. Epub 2012 Jun 26.

PMID:
22733454
45.

Peer review of grant applications: a simple method to identify proposals with discordant reviews.

Giraudeau B, Leyrat C, Le Gouge A, Léger J, Caille A.

PLoS One. 2011;6(11):e27557. doi: 10.1371/journal.pone.0027557. Epub 2011 Nov 14.

46.

Images of asteroid 21 Lutetia: a remnant planetesimal from the early Solar System.

Sierks H, Lamy P, Barbieri C, Koschny D, Rickman H, Rodrigo R, A'Hearn MF, Angrilli F, Barucci MA, Bertaux JL, Bertini I, Besse S, Carry B, Cremonese G, Da Deppo V, Davidsson B, Debei S, De Cecco M, De Leon J, Ferri F, Fornasier S, Fulle M, Hviid SF, Gaskell RW, Groussin O, Gutierrez P, Ip W, Jorda L, Kaasalainen M, Keller HU, Knollenberg J, Kramm R, Kührt E, Küppers M, Lara L, Lazzarin M, Leyrat C, Lopez Moreno JJ, Magrin S, Marchi S, Marzari F, Massironi M, Michalik H, Moissl R, Naletto G, Preusker F, Sabau L, Sabolo W, Scholten F, Snodgrass C, Thomas N, Tubiana C, Vernazza P, Vincent JB, Wenzel KP, Andert T, Pätzold M, Weiss BP.

Science. 2011 Oct 28;334(6055):487-90. doi: 10.1126/science.1207325.

47.

Structure of the vesicular stomatitis virus N⁰-P complex.

Leyrat C, Yabukarski F, Tarbouriech N, Ribeiro EA Jr, Jensen MR, Blackledge M, Ruigrok RW, Jamin M.

PLoS Pathog. 2011 Sep;7(9):e1002248. doi: 10.1371/journal.ppat.1002248. Epub 2011 Sep 22.

48.

The N(0)-binding region of the vesicular stomatitis virus phosphoprotein is globally disordered but contains transient α-helices.

Leyrat C, Jensen MR, Ribeiro EA Jr, Gérard FC, Ruigrok RW, Blackledge M, Jamin M.

Protein Sci. 2011 Mar;20(3):542-56. doi: 10.1002/pro.587. Epub 2011 Feb 16.

49.

Structural disorder in proteins of the rhabdoviridae replication complex.

Leyrat C, Gérard FC, de Almeida Ribeiro E Jr, Ivanov I, Ruigrok RW, Jamin M.

Protein Pept Lett. 2010 Aug;17(8):979-87.

PMID:
20450482
50.

Structure and plasticity of the peptidyl-prolyl isomerase Par27 of Bordetella pertussis revealed by X-ray diffraction and small-angle X-ray scattering.

Clantin B, Leyrat C, Wohlkönig A, Hodak H, Ribeiro Ede A Jr, Martinez N, Baud C, Smet-Nocca C, Villeret V, Jacob-Dubuisson F, Jamin M.

J Struct Biol. 2010 Mar;169(3):253-65. doi: 10.1016/j.jsb.2009.11.007. Epub 2009 Nov 20.

PMID:
19932182

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