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Items: 33

1.

Comparison of the Expression Kinetics and Immunostimulatory Activity of Replicating mRNA, Nonreplicating mRNA, and pDNA after Intradermal Electroporation in Pigs.

Leyman B, Huysmans H, Mc Cafferty S, Combes F, Cox E, Devriendt B, Sanders NN.

Mol Pharm. 2018 Feb 5;15(2):377-384. doi: 10.1021/acs.molpharmaceut.7b00722. Epub 2018 Jan 17.

PMID:
29297692
2.

Evaluation of a xenogeneic vascular endothelial growth factor-2 vaccine in two preclinical metastatic tumor models in mice.

Denies S, Leyman B, Huysmans H, Combes F, Mc Cafferty S, Cicchelero L, Steppe M, De Temmerman J, Sanders NN.

Cancer Immunol Immunother. 2017 Dec;66(12):1545-1555. doi: 10.1007/s00262-017-2046-3. Epub 2017 Aug 3.

PMID:
28776079
3.

Subtherapeutic tetracycline concentrations aggravate Salmonella Typhimurium infection by increasing bacterial virulence.

Verbrugghe E, Van Parys A, Haesendonck R, Leyman B, Boyen F, Haesebrouck F, Pasmans F.

J Antimicrob Chemother. 2016 Aug;71(8):2158-66. doi: 10.1093/jac/dkw152. Epub 2016 May 10.

PMID:
27165787
4.

Erratum: Host Stress Drives Salmonella Recrudescence.

Verbrugghe E, Dhaenens M, Leyman B, Boyen F, Shearer N, Van Parys A, Haesendonck R, Bert W, Favoreel H, Deforce D, Thompson A, Haesebrouck F, Pasmans F.

Sci Rep. 2016 Apr 15;6:23877. doi: 10.1038/srep23877. No abstract available.

5.

Host Stress Drives Salmonella Recrudescence.

Verbrugghe E, Dhaenens M, Leyman B, Boyen F, Shearer N, Van Parys A, Haesendonck R, Bert W, Favoreel H, Deforce D, Thompson A, Haesebrouck F, Pasmans F.

Sci Rep. 2016 Feb 9;6:20849. doi: 10.1038/srep20849. Erratum in: Sci Rep. 2016;6:23877.

6.

Heat-labile enterotoxin of Escherichia coli promotes intestinal colonization of Salmonella enterica.

Verbrugghe E, Van Parys A, Leyman B, Boyen F, Arnouts S, Lundberg U, Ducatelle R, Van den Broeck W, Yekta MA, Cox E, Haesebrouck F, Pasmans F.

Comp Immunol Microbiol Infect Dis. 2015 Dec;43:1-7. doi: 10.1016/j.cimid.2015.09.002. Epub 2015 Sep 16.

PMID:
26616654
7.

HtpG contributes to Salmonella Typhimurium intestinal persistence in pigs.

Verbrugghe E, Van Parys A, Leyman B, Boyen F, Haesebrouck F, Pasmans F.

Vet Res. 2015 Oct 14;46:118. doi: 10.1186/s13567-015-0261-5.

8.

Effect of a DIVA vaccine with and without in-feed use of coated calcium-butyrate on transmission of Salmonella Typhimurium in pigs.

De Ridder L, Maes D, Dewulf J, Pasmans F, Boyen F, Haesebrouck F, Méroc E, Roels S, Leyman B, Butaye P, Van der Stede Y.

BMC Vet Res. 2013 Dec 4;9:243. doi: 10.1186/1746-6148-9-243.

9.

Induction of seroconversion and persistence of Salmonella Typhimurium in pigs are strain dependent.

Van Parys A, Boyen F, Leyman B, Verbrugghe E, Maes D, Haesebrouck F, Pasmans F.

Comp Immunol Microbiol Infect Dis. 2013 Sep;36(5):465-71. doi: 10.1016/j.cimid.2013.03.007. Epub 2013 May 10.

PMID:
23669459
10.

A modified glucomannan mycotoxin-adsorbing agent counteracts the reduced weight gain and diminishes cecal colonization of Salmonella Typhimurium in T-2 toxin exposed pigs.

Verbrugghe E, Croubels S, Vandenbroucke V, Goossens J, De Backer P, Eeckhout M, De Saeger S, Boyen F, Leyman B, Van Parys A, Haesebrouck F, Pasmans F.

Res Vet Sci. 2012 Dec;93(3):1139-41. doi: 10.1016/j.rvsc.2012.07.007. Epub 2012 Jul 24.

PMID:
22835700
11.

Salmonella Typhimurium induces SPI-1 and SPI-2 regulated and strain dependent downregulation of MHC II expression on porcine alveolar macrophages.

Van Parys A, Boyen F, Verbrugghe E, Leyman B, Bram F, Haesebrouck F, Pasmans F.

Vet Res. 2012 Jun 13;43:52. doi: 10.1186/1297-9716-43-52.

12.

Tackling the issue of environmental survival of live Salmonella Typhimurium vaccines: deletion of the lon gene.

Leyman B, Boyen F, Van Parys A, Verbrugghe E, Haesebrouck F, Pasmans F.

Res Vet Sci. 2012 Dec;93(3):1168-72. doi: 10.1016/j.rvsc.2012.05.008. Epub 2012 Jun 9.

PMID:
22683389
13.

Vaccination of pigs reduces Salmonella Typhimurium numbers in a model mimicking pre-slaughter stress.

Leyman B, Boyen F, Verbrugghe E, Parys AV, Haesebrouck F, Pasmans F.

Vet J. 2012 Nov;194(2):250-2. doi: 10.1016/j.tvjl.2012.04.011. Epub 2012 May 19.

PMID:
22609152
14.

T-2 toxin induced Salmonella Typhimurium intoxication results in decreased Salmonella numbers in the cecum contents of pigs, despite marked effects on Salmonella-host cell interactions.

Verbrugghe E, Vandenbroucke V, Dhaenens M, Shearer N, Goossens J, De Saeger S, Eeckhout M, D'Herde K, Thompson A, Deforce D, Boyen F, Leyman B, Van Parys A, De Backer P, Haesebrouck F, Croubels S, Pasmans F.

Vet Res. 2012 Mar 22;43:22. doi: 10.1186/1297-9716-43-22.

15.

Stress induced Salmonella Typhimurium recrudescence in pigs coincides with cortisol induced increased intracellular proliferation in macrophages.

Verbrugghe E, Boyen F, Van Parys A, Van Deun K, Croubels S, Thompson A, Shearer N, Leyman B, Haesebrouck F, Pasmans F.

Vet Res. 2011 Dec 7;42:118. doi: 10.1186/1297-9716-42-118.

16.

The complex interplay between stress and bacterial infections in animals.

Verbrugghe E, Boyen F, Gaastra W, Bekhuis L, Leyman B, Van Parys A, Haesebrouck F, Pasmans F.

Vet Microbiol. 2012 Mar 23;155(2-4):115-27. doi: 10.1016/j.vetmic.2011.09.012. Epub 2011 Sep 16. Review.

PMID:
21963418
17.

Tissue-specific Salmonella Typhimurium gene expression during persistence in pigs.

Van Parys A, Boyen F, Leyman B, Verbrugghe E, Haesebrouck F, Pasmans F.

PLoS One. 2011;6(8):e24120. doi: 10.1371/journal.pone.0024120. Epub 2011 Aug 24.

18.

Salmonella Typhimurium LPS mutations for use in vaccines allowing differentiation of infected and vaccinated pigs.

Leyman B, Boyen F, Van Parys A, Verbrugghe E, Haesebrouck F, Pasmans F.

Vaccine. 2011 May 9;29(20):3679-85. doi: 10.1016/j.vaccine.2011.03.004. Epub 2011 Apr 3.

PMID:
21419163
19.

Salmonella Typhimurium resides largely as an extracellular pathogen in porcine tonsils, independently of biofilm-associated genes csgA, csgD and adrA.

Van Parys A, Boyen F, Volf J, Verbrugghe E, Leyman B, Rychlik I, Haesebrouck F, Pasmans F.

Vet Microbiol. 2010 Jul 29;144(1-2):93-9. doi: 10.1016/j.vetmic.2009.12.021. Epub 2009 Dec 29.

PMID:
20074872
20.

Extensive expression regulation and lack of heterologous enzymatic activity of the Class II trehalose metabolism proteins from Arabidopsis thaliana.

Ramon M, De Smet I, Vandesteene L, Naudts M, Leyman B, Van Dijck P, Rolland F, Beeckman T, Thevelein JM.

Plant Cell Environ. 2009 Aug;32(8):1015-32. doi: 10.1111/j.1365-3040.2009.01985.x. Epub 2009 Apr 2.

21.

Improved drought tolerance without undesired side effects in transgenic plants producing trehalose.

Karim S, Aronsson H, Ericson H, Pirhonen M, Leyman B, Welin B, Mäntylä E, Palva ET, Van Dijck P, Holmström KO.

Plant Mol Biol. 2007 Jul;64(4):371-86. Epub 2007 Apr 24.

PMID:
17453154
22.

Immunogold localization of trehalose-6-phosphate synthase in leaf segments of wild-type and transgenic tobacco plants expressing the AtTPS1 gene from Arabidopsis thaliana.

Almeida AM, Santos M, Villalobos E, Araújo SS, van Dijck P, Leyman B, Cardoso LA, Santos D, Fevereiro PS, Torné JM.

Protoplasma. 2007;230(1-2):41-9. Epub 2006 Nov 21.

PMID:
17111094
23.

ABI4 mediates the effects of exogenous trehalose on Arabidopsis growth and starch breakdown.

Ramon M, Rolland F, Thevelein JM, Van Dijck P, Leyman B.

Plant Mol Biol. 2007 Jan;63(2):195-206. Epub 2006 Sep 23.

PMID:
17031512
24.

Trehalose-6-phosphate synthase as an intrinsic selection marker for plant transformation.

Leyman B, Avonce N, Ramon M, Van Dijck P, Iturriaga G, Thevelein JM.

J Biotechnol. 2006 Feb 10;121(3):309-17. Epub 2005 Nov 4.

PMID:
16271790
25.

Trehalose metabolism and glucose sensing in plants.

Avonce N, Leyman B, Thevelein J, Iturriaga G.

Biochem Soc Trans. 2005 Feb;33(Pt 1):276-9. Erratum in: Biochem Soc Trans. 2005 Dec;33(Pt 6):1547.

PMID:
15667325
26.

The Arabidopsis trehalose-6-P synthase AtTPS1 gene is a regulator of glucose, abscisic acid, and stress signaling.

Avonce N, Leyman B, Mascorro-Gallardo JO, Van Dijck P, Thevelein JM, Iturriaga G.

Plant Physiol. 2004 Nov;136(3):3649-59. Epub 2004 Oct 29.

27.

New selection marker for plant transformation.

Leyman B, Avonce N, Ramon M, Van Dijck P, Thevelein JM, Iturriaga G.

Methods Mol Biol. 2004;267:385-96.

PMID:
15269438
28.

The abscisic acid-related SNARE homolog NtSyr1 contributes to secretion and growth: evidence from competition with its cytosolic domain.

Geelen D, Leyman B, Batoko H, Di Sansebastiano GP, Moore I, Blatt MR.

Plant Cell. 2002 Feb;14(2):387-406. Erratum in: Plant Cell 2002 Apr;14(4):963. Di Sansabastiano Gian-Pietro [corrected to Di Sansebastiano Gian-Pietro].

29.

An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana.

Leyman B, Van Dijck P, Thevelein JM.

Trends Plant Sci. 2001 Nov;6(11):510-3.

PMID:
11701378
30.

Localization and control of expression of Nt-Syr1, a tobacco SNARE protein.

Leyman B, Geelen D, Blatt MR.

Plant J. 2000 Nov;24(3):369-81.

31.

A tobacco syntaxin with a role in hormonal control of guard cell ion channels.

Leyman B, Geelen D, Quintero FJ, Blatt MR.

Science. 1999 Jan 22;283(5401):537-40.

32.

NodS is an S-adenosyl-L-methionine-dependent methyltransferase that methylates chitooligosaccharides deacetylated at the non-reducing end.

Geelen D, Leyman B, Mergaert P, Klarskov K, Van Montagu M, Geremia R, Holsters M.

Mol Microbiol. 1995 Jul;17(2):387-97.

PMID:
7494487
33.

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