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Items: 15

1.

MicroRNA-155 is essential for the optimal proliferation and survival of plasmablast B cells.

Arbore G, Henley T, Biggins L, Andrews S, Vigorito E, Turner M, Leyland R.

Life Sci Alliance. 2019 May 16;2(3). pii: e201800244. doi: 10.26508/lsa.201800244. Print 2019 Jun.

2.

Epigenomic Modifications Mediating Antibody Maturation.

Sheppard EC, Morrish RB, Dillon MJ, Leyland R, Chahwan R.

Front Immunol. 2018 Feb 26;9:355. doi: 10.3389/fimmu.2018.00355. eCollection 2018. Review.

3.

A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist.

Leyland R, Watkins A, Mulgrew KA, Holoweckyj N, Bamber L, Tigue NJ, Offer E, Andrews J, Yan L, Mullins S, Oberst MD, Coates Ulrichsen J, Leinster DA, McGlinchey K, Young L, Morrow M, Hammond SA, Mallinder P, Herath A, Leow CC, Wilkinson RW, Stewart R.

Clin Cancer Res. 2017 Jul 1;23(13):3416-3427. doi: 10.1158/1078-0432.CCR-16-2000. Epub 2017 Jan 9.

4.

Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery.

Mosely SI, Prime JE, Sainson RC, Koopmann JO, Wang DY, Greenawalt DM, Ahdesmaki MJ, Leyland R, Mullins S, Pacelli L, Marcus D, Anderton J, Watkins A, Coates Ulrichsen J, Brohawn P, Higgs BW, McCourt M, Jones H, Harper JA, Morrow M, Valge-Archer V, Stewart R, Dovedi SJ, Wilkinson RW.

Cancer Immunol Res. 2017 Jan;5(1):29-41. doi: 10.1158/2326-6066.CIR-16-0114. Epub 2016 Dec 6.

5.

Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy.

Williams GS, Mistry B, Guillard S, Ulrichsen JC, Sandercock AM, Wang J, González-Muñoz A, Parmentier J, Black C, Soden J, Freeth J, Jovanović J, Leyland R, Al-Lamki RS, Leishman AJ, Rust SJ, Stewart R, Jermutus L, Bradley JR, Bedian V, Valge-Archer V, Minter R, Wilkinson RW.

Oncotarget. 2016 Oct 18;7(42):68278-68291. doi: 10.18632/oncotarget.11943.

6.

A survey of Lab Tests Online-UK users: a key resource for patients to empower and help them understand their laboratory test results.

Leyland R, Freedman DB.

Ann Clin Biochem. 2016 Nov;53(6):669-679. doi: 10.1177/0004563216631774. Epub 2016 Jul 20.

PMID:
27013742
7.

MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis.

Nakagawa R, Leyland R, Meyer-Hermann M, Lu D, Turner M, Arbore G, Phan TG, Brink R, Vigorito E.

J Clin Invest. 2016 Jan;126(1):377-88. doi: 10.1172/JCI82914. Epub 2015 Dec 14.

8.

Multicentre study of investigation and management of inpatient hyponatraemia in the UK.

Tzoulis P, Evans R, Falinska A, Barnard M, Tan T, Woolman E, Leyland R, Martin N, Edwards R, Scott R, Gurazada K, Parsons M, Nair D, Khoo B, Bouloux PM.

Postgrad Med J. 2014 Dec;90(1070):694-8. doi: 10.1136/postgradmedj-2014-132885. Epub 2014 Nov 14.

9.

The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation.

Lu D, Nakagawa R, Lazzaro S, Staudacher P, Abreu-Goodger C, Henley T, Boiani S, Leyland R, Galloway A, Andrews S, Butcher G, Nutt SL, Turner M, Vigorito E.

J Exp Med. 2014 Oct 20;211(11):2183-98. doi: 10.1084/jem.20140338. Epub 2014 Oct 6.

10.

miR-155: an ancient regulator of the immune system.

Vigorito E, Kohlhaas S, Lu D, Leyland R.

Immunol Rev. 2013 May;253(1):146-57. doi: 10.1111/imr.12057. Review.

PMID:
23550644
11.

MicroRNA-155 is required for Mycobacterium bovis BCG-mediated apoptosis of macrophages.

Ghorpade DS, Leyland R, Kurowska-Stolarska M, Patil SA, Balaji KN.

Mol Cell Biol. 2012 Jun;32(12):2239-53. doi: 10.1128/MCB.06597-11. Epub 2012 Apr 2.

12.

Characterisation of 5-HT3C, 5-HT3D and 5-HT3E receptor subunits: evolution, distribution and function.

Holbrook JD, Gill CH, Zebda N, Spencer JP, Leyland R, Rance KH, Trinh H, Balmer G, Kelly FM, Yusaf SP, Courtenay N, Luck J, Rhodes A, Modha S, Moore SE, Sanger GJ, Gunthorpe MJ.

J Neurochem. 2009 Jan;108(2):384-96. doi: 10.1111/j.1471-4159.2008.05775.x. Epub 2008 Nov 29.

13.

Outbreak of Escherichia coli O157:H7 gastroenteritis associated with consumption of beef donairs, Edmonton, Alberta, May-June 2006.

Honish L, Zazulak I, Mahabeer R, Krywiak K, Leyland R, Hislop N, Chui L.

Can Commun Dis Rep. 2007 Jan 15;33(2):14-9. English, French. No abstract available.

14.

The effects of tetanus toxin-induced limbic epilepsy on the exploratory response to novelty in the rat.

Mellanby J, Johansen-Berg H, Leyland R, Milward AJ.

Epilepsia. 1999 Aug;40(8):1058-61.

15.

Outbreak of Campylobacter enteritis due to consumption of raw milk.

McNaughton RD, Leyland R, Mueller L.

Can Med Assoc J. 1982 Mar 15;126(6):657-8. No abstract available.

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