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Items: 1 to 50 of 81

1.

Claudin 1 Is Highly Upregulated by PKC in MCF7 Human Breast Cancer Cells and Correlates Positively with PKCε in Patient Biopsies.

Blanchard AA, Ma X, Wang N, Hombach-Klonisch S, Penner C, Ozturk A, Klonisch T, Pitz M, Murphy L, Leygue E, Myal Y.

Transl Oncol. 2019 Mar;12(3):561-575. doi: 10.1016/j.tranon.2018.12.011. Epub 2019 Jan 15.

2.

Population-based analysis of breast cancer treatment by intrinsic sub-type in Manitoba, Canada.

Hammond E, Shu E, Sawchuk K, Myal Y, Raouf A, Klonisch T, Hombach-Klonisch S, Leygue E, Kung S, Safneck J, Mowat M, Xu W, Murphy L, Pitz M.

Cancer Epidemiol. 2016 Dec;45:82-90. doi: 10.1016/j.canep.2016.10.006. Epub 2016 Oct 19.

PMID:
27770672
3.

Identification of Claudin 1 Transcript Variants in Human Invasive Breast Cancer.

Blanchard AA, Zelinski T, Xie J, Cooper S, Penner C, Leygue E, Myal Y.

PLoS One. 2016 Sep 20;11(9):e0163387. doi: 10.1371/journal.pone.0163387. eCollection 2016.

4.

Idiopathic Hypogonadotropic Hypogonadism Caused by Inactivating Mutations in SRA1.

Kotan LD, Cooper C, Darcan Ş, Carr IM, Özen S, Yan Y, Hamedani MK, Gürbüz F, Mengen E, Turan İ, Ulubay A, Akkuş G, Yüksel B, Topaloğlu AK, Leygue E.

J Clin Res Pediatr Endocrinol. 2016 Jun 5;8(2):125-34. doi: 10.4274/jcrpe.3248. Epub 2016 Apr 18.

5.

Dynamic Histone Acetylation of H3K4me3 Nucleosome Regulates MCL1 Pre-mRNA Splicing.

Khan DH, Gonzalez C, Tailor N, Hamedani MK, Leygue E, Davie JR.

J Cell Physiol. 2016 Oct;231(10):2196-204. doi: 10.1002/jcp.25337. Epub 2016 Mar 6.

PMID:
26864447
6.

Claudin 1 in Breast Cancer: New Insights.

Zhou B, Moodie A, Blanchard AA, Leygue E, Myal Y.

J Clin Med. 2015 Nov 27;4(12):1960-76. doi: 10.3390/jcm4121952. Review.

7.

The steroid receptor RNA activator protein (SRAP) controls cancer cell migration/motility.

Yan Y, Cooper C, Hamedani MK, Guppy B, Xu W, Tsuyuki D, Zhang C, Nugent Z, Blanchard A, Davie JR, McManus K, Murphy LC, Myal Y, Leygue E.

FEBS Lett. 2015 Dec 21;589(24 Pt B):4010-8. doi: 10.1016/j.febslet.2015.11.007. Epub 2015 Nov 17.

8.

PDK2-mediated alternative splicing switches Bnip3 from cell death to cell survival.

Gang H, Dhingra R, Lin J, Hai Y, Aviv Y, Margulets V, Hamedani M, Thanasupawat T, Leygue E, Klonisch T, Davie JR, Kirshenbaum LA.

J Cell Biol. 2015 Sep 28;210(7):1101-15. doi: 10.1083/jcb.201504047.

9.

Claudin 1 promotes migration and increases sensitivity to tamoxifen and anticancer drugs in luminal-like human breast cancer cells MCF7.

Zhou B, Blanchard A, Wang N, Ma X, Han J, Schroedter I, Leygue E, Myal Y.

Cancer Invest. 2015;33(9):429-39. doi: 10.3109/07357907.2015.1060996. Epub 2015 Aug 17.

PMID:
26288115
10.

Claudin 1 Promotes Migration and Increases Sensitivity to Tamoxifen and Anticancer Drugs in Luminal-like Human Breast Cancer Cells MCF7.

Zhou B, Blanchard A, Wang N, Ma X, Han J, Schroedter I, Leygue E, Myal Y.

Cancer Invest. 2015 Aug 17. [Epub ahead of print]

PMID:
26279089
11.

Towards further defining the proteome of mouse saliva.

Blanchard AA, Ezzati P, Shamshurin D, Nistor AC, Leygue E, Wilkins JA, Myal Y.

Proteome Sci. 2015 Feb 25;13:10. doi: 10.1186/s12953-015-0068-3. eCollection 2015.

12.

RNA-dependent dynamic histone acetylation regulates MCL1 alternative splicing.

Khan DH, Gonzalez C, Cooper C, Sun JM, Chen HY, Healy S, Xu W, Smith KT, Workman JL, Leygue E, Davie JR.

Nucleic Acids Res. 2014 Feb;42(3):1656-70. doi: 10.1093/nar/gkt1134. Epub 2013 Nov 14.

13.

Steroid receptor RNA activator protein (SRAP) expression as a prognostic factor in ER+ human breast tumors.

Yan Y, Penner CC, Skliris GP, Cooper C, Nugent Z, Blanchard A, Hamedani MK, Wang X, Myal Y, Murphy LC, Leygue E.

J Cancer Res Clin Oncol. 2013 Oct;139(10):1637-47. doi: 10.1007/s00432-013-1485-2. Epub 2013 Aug 2.

PMID:
23907597
14.

Claudin 1 expression in basal-like breast cancer is related to patient age.

Blanchard AA, Ma X, Dueck KJ, Penner C, Cooper SC, Mulhall D, Murphy LC, Leygue E, Myal Y.

BMC Cancer. 2013 May 30;13:268. doi: 10.1186/1471-2407-13-268.

15.

Expression of both estrogen receptor-beta 1 (ER-β1) and its co-regulator steroid receptor RNA activator protein (SRAP) are predictive for benefit from tamoxifen therapy in patients with estrogen receptor-alpha (ER-α)-negative early breast cancer (EBC).

Yan Y, Li X, Blanchard A, Bramwell VH, Pritchard KI, Tu D, Shepherd L, Myal Y, Penner C, Watson PH, Leygue E, Murphy LC.

Ann Oncol. 2013 Aug;24(8):1986-93. doi: 10.1093/annonc/mdt132. Epub 2013 Apr 11.

PMID:
23579816
16.

A bi-faceted role of estrogen receptor β in breast cancer.

Leygue E, Murphy LC.

Endocr Relat Cancer. 2013 May 30;20(3):R127-39. doi: 10.1530/ERC-12-0389. Print 2013 Jun. Review.

PMID:
23533249
17.

The role of estrogen receptor-β in breast cancer.

Murphy LC, Leygue E.

Semin Reprod Med. 2012 Jan;30(1):5-13. doi: 10.1055/s-0031-1299592. Epub 2012 Jan 23. Review.

PMID:
22271289
18.

Steroid Receptor RNA Activator bi-faceted genetic system: Heads or Tails?

Cooper C, Vincett D, Yan Y, Hamedani MK, Myal Y, Leygue E.

Biochimie. 2011 Nov;93(11):1973-80. doi: 10.1016/j.biochi.2011.07.002. Epub 2011 Jul 12. Review.

PMID:
21771633
19.

Comparative evaluation of ERα and ERβ significance in breast cancer: state of the art.

Leygue E, Murphy L.

Expert Rev Endocrinol Metab. 2011 May;6(3):333-343. doi: 10.1586/eem.11.27.

PMID:
30754114
20.

A novel hypoxia-inducible spliced variant of mitochondrial death gene Bnip3 promotes survival of ventricular myocytes.

Gang H, Hai Y, Dhingra R, Gordon JW, Yurkova N, Aviv Y, Li H, Aguilar F, Marshall A, Leygue E, Kirshenbaum LA.

Circ Res. 2011 Apr 29;108(9):1084-92. doi: 10.1161/CIRCRESAHA.110.238709. Epub 2011 Mar 17.

PMID:
21415393
21.

Claudin 1 in breast tumorigenesis: revelation of a possible novel "claudin high" subset of breast cancers.

Myal Y, Leygue E, Blanchard AA.

J Biomed Biotechnol. 2010;2010:956897. doi: 10.1155/2010/956897. Epub 2010 May 13.

22.

The steroid receptor RNA activator protein is recruited to promoter regions and acts as a transcriptional repressor.

Chooniedass-Kothari S, Hamedani MK, Auge C, Wang X, Carascossa S, Yan Y, Cooper C, Vincett D, Myal Y, Jalaguier S, Cavailles V, Leygue E.

FEBS Lett. 2010 Jun 3;584(11):2218-24. doi: 10.1016/j.febslet.2010.04.022. Epub 2010 Apr 14.

23.

The protein encoded by the functional steroid receptor RNA activator is a new modulator of ER alpha transcriptional activity.

Chooniedass-Kothari S, Vincett D, Yan Y, Cooper C, Hamedani MK, Myal Y, Leygue E.

FEBS Lett. 2010 Mar 19;584(6):1174-80. doi: 10.1016/j.febslet.2010.02.024. Epub 2010 Feb 11.

24.

Computational modelling of protein interactions: energy minimization for the refinement and scoring of association decoys.

Dibrov A, Myal Y, Leygue E.

Acta Biotheor. 2009 Dec;57(4):419-28. doi: 10.1007/s10441-009-9085-x. Epub 2009 Sep 23.

PMID:
19774465
25.

Steroid Receptor RNA Activator Protein (SRAP): a potential new prognostic marker for estrogen receptor-positive/node-negative/younger breast cancer patients.

Yan Y, Skliris GP, Penner C, Chooniedass-Kothari S, Cooper C, Nugent Z, Blanchard A, Watson PH, Myal Y, Murphy LC, Leygue E.

Breast Cancer Res. 2009;11(5):R67. doi: 10.1186/bcr2359.

26.

Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotides.

Cooper C, Guo J, Yan Y, Chooniedass-Kothari S, Hube F, Hamedani MK, Murphy LC, Myal Y, Leygue E.

Nucleic Acids Res. 2009 Jul;37(13):4518-31. doi: 10.1093/nar/gkp441. Epub 2009 May 29.

27.

Claudins 1, 3, and 4 protein expression in ER negative breast cancer correlates with markers of the basal phenotype.

Blanchard AA, Skliris GP, Watson PH, Murphy LC, Penner C, Tomes L, Young TL, Leygue E, Myal Y.

Virchows Arch. 2009 Jun;454(6):647-56. doi: 10.1007/s00428-009-0770-6. Epub 2009 Apr 23.

PMID:
19387682
28.

Expression of small breast epithelial mucin (SBEM) protein in tissue microarrays (TMAs) of primary invasive breast cancers.

Skliris GP, Hubé F, Gheorghiu I, Mutawe MM, Penner C, Watson PH, Murphy LC, Leygue E, Myal Y.

Histopathology. 2008 Feb;52(3):355-69. doi: 10.1111/j.1365-2559.2007.02955.x.

29.

Estrogen receptor alpha negative breast cancer patients: estrogen receptor beta as a therapeutic target.

Skliris GP, Leygue E, Watson PH, Murphy LC.

J Steroid Biochem Mol Biol. 2008 Mar;109(1-2):1-10. doi: 10.1016/j.jsbmb.2007.12.010. Epub 2007 Dec 8. Review.

PMID:
18243688
31.

Gene expression profiling of early involuting mammary gland reveals novel genes potentially relevant to human breast cancer.

Blanchard A, Shiu R, Booth S, Sorensen G, DeCorby N, Nistor A, Wong P, Leygue E, Myal Y.

Front Biosci. 2007 Jan 1;12:2221-32.

PMID:
17127459
32.

Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours.

Skliris GP, Leygue E, Curtis-Snell L, Watson PH, Murphy LC.

Br J Cancer. 2006 Sep 4;95(5):616-26. Epub 2006 Aug 1.

33.

Alternative splicing of the first intron of the steroid receptor RNA activator (SRA) participates in the generation of coding and noncoding RNA isoforms in breast cancer cell lines.

Hube F, Guo J, Chooniedass-Kothari S, Cooper C, Hamedani MK, Dibrov AA, Blanchard AA, Wang X, Deng G, Myal Y, Leygue E.

DNA Cell Biol. 2006 Jul;25(7):418-28.

PMID:
16848684
34.

Expression of two breast-specific molecules in the lung.

Hube F, Myal Y, Leygue E, Rollin J, Gruel Y.

J Mol Diagn. 2006 Jul;8(3):390-1; author reply 391-3. No abstract available.

35.

Identification of an octamer-binding site controlling the activity of the small breast epithelial mucin gene promoter.

Hubé F, Chooniedass-Kothari S, Hamedani MK, Miksicek RJ, Leygue E, Myal Y.

Front Biosci. 2006 Sep 1;11:2483-95.

PMID:
16720387
36.

Differential expression of claudin 1, 3, and 4 during normal mammary gland development in the mouse.

Blanchard AA, Watson PH, Shiu RP, Leygue E, Nistor A, Wong P, Myal Y.

DNA Cell Biol. 2006 Feb;25(2):79-86.

PMID:
16460231
37.
38.

The steroid receptor RNA activator protein is expressed in breast tumor tissues.

Chooniedass-Kothari S, Hamedani MK, Troup S, Hubé F, Leygue E.

Int J Cancer. 2006 Feb 15;118(4):1054-9.

39.

Inducible upregulation of oestrogen receptor-beta1 affects oestrogen and tamoxifen responsiveness in MCF7 human breast cancer cells.

Murphy LC, Peng B, Lewis A, Davie JR, Leygue E, Kemp A, Ung K, Vendetti M, Shiu R.

J Mol Endocrinol. 2005 Apr;34(2):553-66.

PMID:
15821116
40.

Human small breast epithelial mucin: the promise of a new breast tumor biomarker.

Hubé F, Mutawe M, Leygue E, Myal Y.

DNA Cell Biol. 2004 Dec;23(12):842-9.

PMID:
15684711
41.

The steroid receptor RNA activator is the first functional RNA encoding a protein.

Chooniedass-Kothari S, Emberley E, Hamedani MK, Troup S, Wang X, Czosnek A, Hube F, Mutawe M, Watson PH, Leygue E.

FEBS Lett. 2004 May 21;566(1-3):43-7.

42.

Relationship between mammaglobin expression and estrogen receptor status in breast tumors.

Guan XF, Hamedani MK, Adeyinka A, Walker C, Kemp A, Murphy LC, Watson PH, Leygue E.

Endocrine. 2003 Aug;21(3):245-50.

PMID:
14515009
43.

Psoriasin interacts with Jab1 and influences breast cancer progression.

Emberley ED, Niu Y, Leygue E, Tomes L, Gietz RD, Murphy LC, Watson PH.

Cancer Res. 2003 Apr 15;63(8):1954-61.

44.

Putative functional characteristics of human estrogen receptor-beta isoforms.

Peng B, Lu B, Leygue E, Murphy LC.

J Mol Endocrinol. 2003 Feb;30(1):13-29.

PMID:
12580758
45.

Identification of new human coding steroid receptor RNA activator isoforms.

Emberley E, Huang GJ, Hamedani MK, Czosnek A, Ali D, Grolla A, Lu B, Watson PH, Murphy LC, Leygue E.

Biochem Biophys Res Commun. 2003 Feb 7;301(2):509-15. Erratum in: Biochem Biophys Res Commun. 2003 Aug 1;307(3):757.

PMID:
12565891
46.

Relationship of coregulator and oestrogen receptor isoform expression to de novo tamoxifen resistance in human breast cancer.

Murphy LC, Leygue E, Niu Y, Snell L, Ho SM, Watson PH.

Br J Cancer. 2002 Dec 2;87(12):1411-6.

47.

Identification of a novel breast- and salivary gland-specific, mucin-like gene strongly expressed in normal and tumor human mammary epithelium.

Miksicek RJ, Myal Y, Watson PH, Walker C, Murphy LC, Leygue E.

Cancer Res. 2002 May 15;62(10):2736-40.

48.
49.

Altered expression of estrogen receptor coregulators during human breast tumorigenesis.

Murphy LC, Simon SL, Parkes A, Leygue E, Dotzlaw H, Snell L, Troup S, Adeyinka A, Watson PH.

Cancer Res. 2000 Nov 15;60(22):6266-71.

50.

Lumican and decorin are differentially expressed in human breast carcinoma.

Leygue E, Snell L, Dotzlaw H, Troup S, Hiller-Hitchcock T, Murphy LC, Roughley PJ, Watson PH.

J Pathol. 2000 Nov;192(3):313-20.

PMID:
11054714

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