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PARaDIM - A PHITS-based Monte Carlo tool for internal dosimetry with tetrahedral mesh computational phantoms.

Carter LM, Crawford TM, Sato T, Furuta T, Choi C, Kim CH, Brown JL, Bolch WE, Zanzonico PB, Lewis JS.

J Nucl Med. 2019 Jun 14. pii: jnumed.119.229013. doi: 10.2967/jnumed.119.229013. [Epub ahead of print]


Acid specific dark quencher QC1 pHLIP for multi-spectral optoacoustic diagnoses of breast cancer.

Roberts S, Strome A, Choi C, Andreou C, Kossatz S, Brand C, Williams T, Bradbury M, Kircher MF, Reshetnyak YK, Grimm J, Lewis JS, Reiner T.

Sci Rep. 2019 Jun 12;9(1):8550. doi: 10.1038/s41598-019-44873-1.


Temporal Modulation of HER2 Membrane Availability Increases Pertuzumab Uptake and Pretargeted Molecular Imaging of Gastric Tumors.

Pereira PM, Mandleywala K, Ragupathi A, Carter LM, Goos JACM, Janjigian YY, Lewis JS.

J Nucl Med. 2019 Jun 6. pii: jnumed.119.225813. doi: 10.2967/jnumed.119.225813. [Epub ahead of print]


A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals.

Sharma SK, Lyashchenko SK, Park HA, Pillarsetty N, Roux Y, Wu J, Poty S, Tully KM, Poirier JT, Lewis JS.

Nucl Med Biol. 2019 May 3;71:32-38. doi: 10.1016/j.nucmedbio.2019.04.005. [Epub ahead of print]


Dual-Sized Microparticle System for Generating Suppressive Dendritic Cells Prevents and Reverses Type 1 Diabetes in the Nonobese Diabetic Mouse Model.

Lewis JS, Stewart JM, Marshall GP, Carstens MR, Zhang Y, Dolgova NV, Xia C, Brusko TM, Wasserfall CH, Clare-Salzler MJ, Atkinson MA, Keselowsky BG.

ACS Biomater Sci Eng. 2019 May 13;5(5):2631-2646. doi: 10.1021/acsbiomaterials.9b00332. Epub 2019 Mar 26.


Multimodal Positron Emission Tomography Imaging to Quantify Uptake of 89Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall.

Lobatto ME, Binderup T, Robson PM, Giesen LFP, Calcagno C, Witjes J, Fay F, Baxter S, Wessel CH, Eldib M, Bini J, Carlin SD, Stroes ESG, Storm G, Kjaer A, Lewis JS, Reiner T, Fayad ZA, Mulder WJM, Pérez-Medina C.

Bioconjug Chem. 2019 Jun 7. doi: 10.1021/acs.bioconjchem.9b00256. [Epub ahead of print]


An Empirical Study of the Role of Student Employment in Leadership Learning.

Lewis JS.

New Dir Stud Leadersh. 2019 Jun;2019(162):37-47. doi: 10.1002/yd.20332.


Isavuconazole to prevent invasive fungal infection in immunocompromised adults: Initial experience at an academic medical centre.

Bowen CD, Tallman GB, Hakki M, Lewis Ⅱ JS.

Mycoses. 2019 May 3. doi: 10.1111/myc.12924. [Epub ahead of print]


The Impact of Positron Range on PET Resolution, Evaluated with Phantoms and PHITS Monte Carlo Simulations for Conventional and Non-conventional Radionuclides.

Carter LM, Kesner AL, Pratt EC, Sanders VA, Massicano AVF, Cutler CS, Lapi SE, Lewis JS.

Mol Imaging Biol. 2019 Apr 18. doi: 10.1007/s11307-019-01337-2. [Epub ahead of print]


UV Signature Mutations Reclassify Salivary High-grade Neuroendocrine Carcinomas as Occult Metastatic Cutaneous Merkel Cell Carcinomas.

Sun L, Cliften PF, Duncavage EJ, Lewis JS Jr, Chernock RD.

Am J Surg Pathol. 2019 May;43(5):682-687. doi: 10.1097/PAS.0000000000001231.


Inter-observer Variability in the Diagnosis of Proliferative Verrucous Leukoplakia: Clinical Implications for Oral and Maxillofacial Surgeon Understanding: A Collaborative Pilot Study.

Upadhyaya JD, Fitzpatrick SG, Cohen DM, Bilodeau EA, Bhattacharyya I, Lewis JS Jr, Lai J, Wright JM, Bishop JA, Leon ME, Islam MN, Seethala R, Padilla RJ, Carlos R, Müller S, Thompson LDR.

Head Neck Pathol. 2019 Apr 10. doi: 10.1007/s12105-019-01035-z. [Epub ahead of print]


Isavuconazole prophylaxis in patients with hematologic malignancies and hematopoietic-cell transplant recipients.

Fontana L, Perlin DS, Zhao Y, Noble BN, Lewis JS, Strasfeld L, Hakki M.

Clin Infect Dis. 2019 Apr 8. pii: ciz282. doi: 10.1093/cid/ciz282. [Epub ahead of print]


A Conversation Between Michael Phelps and Jason Lewis.

Phelps ME, Lewis JS.

J Nucl Med. 2019 Apr;60(4):439-442. doi: 10.2967/jnumed.119.228296. No abstract available.


Toward the Optimization of Click-Mediated Pretargeted Radioimmunotherapy.

Membreno R, Keinänen OM, Cook BE, Tully KM, Fung KC, Lewis JS, Zeglis BM.

Mol Pharm. 2019 May 6;16(5):2259-2263. doi: 10.1021/acs.molpharmaceut.9b00062. Epub 2019 Apr 9.


Hypopharyngeal Skin Cancer Following Total Laryngectomy and Pectoralis Flap Reconstruction: Case Report and Literature Review.

Amin SN, Shinn JR, Tang A, Lewis JS Jr, Mannion K.

Head Neck Pathol. 2019 Mar 19. doi: 10.1007/s12105-019-01029-x. [Epub ahead of print]


Assessment of simplified methods for quantification of 18F-FDHT uptake in patients with metastatic castration-resistant prostate cancer.

Kramer GM, Yaqub M, Vargas HA, Schuit R, Windhorst AD, van den Eertwegh A, van der Veldt A, Bergman A, Burnazi E, Lewis JS, Chua SS, Staton K, Beattie BJ, Humm JL, Davis ID, Weickhardt A, Scott A, Morris MJ, Hoekstra OS, Lammertsma AA.

J Nucl Med. 2019 Mar 8. pii: jnumed.118.220111. doi: 10.2967/jnumed.118.220111. [Epub ahead of print]


Recycling of single-stranded DNA-binding protein by the bacterial replisome.

Spenkelink LM, Lewis JS, Jergic S, Xu ZQ, Robinson A, Dixon NE, van Oijen AM.

Nucleic Acids Res. 2019 May 7;47(8):4111-4123. doi: 10.1093/nar/gkz090.


Utility and Practicality of Multi-level Sectioning and Upfront Unstained Slide Cutting in Head and Neck Biopsies: A Critical Analysis.

Saab-Chalhoub MW, Lewis JS Jr.

Head Neck Pathol. 2019 Feb 13. doi: 10.1007/s12105-019-01016-2. [Epub ahead of print]


Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response.

Ghodke H, Paudel BP, Lewis JS, Jergic S, Gopal K, Romero ZJ, Wood EA, Woodgate R, Cox MM, van Oijen AM.

Elife. 2019 Feb 5;8. pii: e42761. doi: 10.7554/eLife.42761.


Shining a Spotlight on DNA: Single-Molecule Methods to Visualise DNA.

Kaur G, Lewis JS, van Oijen AM.

Molecules. 2019 Jan 30;24(3). pii: E491. doi: 10.3390/molecules24030491. Review.


Current Concepts and Future Directions in the Pharmacology and Treatment of Coccidioidomycosis.

Thompson GR 3rd, Lewis JS 2nd, Nix DE, Patterson TF.

Med Mycol. 2019 Feb 1;57(Supplement_1):S76-S84. doi: 10.1093/mmy/myy029. Review.


Early onset oral tongue squamous cell carcinoma: Associated factors and patient outcomes.

Campbell BR, Sanders CB, Netterville JL, Sinard RJ, Rohde SL, Langerman A, Mannion K, Kim YJ, Murphy BA, Lewis JS Jr, Warner JL, Smith DK, Lang Kuhs KA.

Head Neck. 2019 Jun;41(6):1952-1960. doi: 10.1002/hed.25650. Epub 2019 Jan 11.


Trastuzumab gold-conjugates: synthetic approach and in vitro evaluation of anticancer activities in breast cancer cell lines.

Curado N, Dewaele-Le Roi G, Poty S, Lewis JS, Contel M.

Chem Commun (Camb). 2019 Jan 29;55(10):1394-1397. doi: 10.1039/c8cc08769e.


Self-efficacy and risk of persistent shoulder pain: results of a Classification and Regression Tree (CART) analysis.

Chester R, Khondoker M, Shepstone L, Lewis JS, Jerosch-Herold C.

Br J Sports Med. 2019 Jul;53(13):825-834. doi: 10.1136/bjsports-2018-099450. Epub 2019 Jan 9.


Cryotherapy or gradual reloading exercises in acute presentations of rotator cuff tendinopathy: a randomised controlled trial.

Dupuis F, Barrett E, Dubé MO, McCreesh KM, Lewis JS, Roy JS.

BMJ Open Sport Exerc Med. 2018 Dec 26;4(1):e000477. doi: 10.1136/bmjsem-2018-000477. eCollection 2018.


Secretory Carcinoma of the Thyroid Gland: Report of a Highly Aggressive Case Clinically Mimicking Undifferentiated Carcinoma and Review of the Literature.

Desai MA, Mehrad M, Ely KA, Bishop JA, Netterville J, Aulino JM, Lewis JS Jr.

Head Neck Pathol. 2018 Dec 18. doi: 10.1007/s12105-018-0995-2. [Epub ahead of print]


Latent, Immunosuppressive Nature of Poly(lactic-co-glycolic acid) Microparticles.

Allen RP, Bolandparvaz A, Ma JA, Manickam VA, Lewis JS.

ACS Biomater Sci Eng. 2018 Mar 12;4(3):900-918. doi: 10.1021/acsbiomaterials.7b00831. Epub 2018 Feb 3.


Early onset oral tongue cancer in the United States: A literature review.

Campbell BR, Netterville JL, Sinard RJ, Mannion K, Rohde SL, Langerman A, Kim YJ, Lewis JS Jr, Lang Kuhs KA.

Oral Oncol. 2018 Dec;87:1-7. doi: 10.1016/j.oraloncology.2018.10.009. Epub 2018 Oct 14. Review.


Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy.

Pereira PMR, Sharma SK, Carter LM, Edwards KJ, Pourat J, Ragupathi A, Janjigian YY, Durack JC, Lewis JS.

Nat Commun. 2018 Dec 3;9(1):5137. doi: 10.1038/s41467-018-07608-w.


Data Set for the Reporting of Carcinomas of the Nasopharynx and Oropharynx: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting.

Lewis JS Jr, Adelstein DJ, Agaimy A, Carlson DL, Faquin WC, Helliwell T, Hille J, Ng T, Nicholls JM, O'Sullivan B, Thompson LDR.

Arch Pathol Lab Med. 2019 Apr;143(4):447-451. doi: 10.5858/arpa.2018-0405-SA. Epub 2018 Nov 30.


EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer.

Sanchez-Vega F, Hechtman JF, Castel P, Ku GY, Tuvy Y, Won H, Fong CJ, Bouvier N, Nanjangud GJ, Soong J, Vakiani E, Schattner M, Kelsen DP, Lefkowitz RA, Brown K, Lacouture ME, Capanu M, Mattar M, Qeriqi B, Cecchi F, Tian Y, Hembrough T, Nagy RJ, Lanman RB, Larson SM, Pandit-Taskar N, Schöder H, Iacobuzio-Donahue CA, Ilson DH, Weber WA, Berger MF, de Stanchina E, Taylor BS, Lewis JS, Solit DB, Carrasquillo JA, Scaltriti M, Schultz N, Janjigian YY.

Cancer Discov. 2019 Feb;9(2):199-209. doi: 10.1158/2159-8290.CD-18-0598. Epub 2018 Nov 21.


Biodistribution and radiation dose estimates for 68Ga-DOTA-JR11 in patients with metastatic neuroendocrine tumors.

Krebs S, Pandit-Taskar N, Reidy D, Beattie BJ, Lyashchenko SK, Lewis JS, Bodei L, Weber WA, O'Donoghue JA.

Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):677-685. doi: 10.1007/s00259-018-4193-y. Epub 2018 Oct 29.


A randomised controlled trial of long-chain omega-3 polyunsaturated fatty acids in the management of rotator cuff related shoulder pain.

Sandford FM, Sanders TA, Wilson H, Lewis JS.

BMJ Open Sport Exerc Med. 2018 Oct 19;4(1):e000414. doi: 10.1136/bmjsem-2018-000414. eCollection 2018.


Leveraging Bioorthogonal Click Chemistry to Improve 225Ac-Radioimmunotherapy of Pancreatic Ductal Adenocarcinoma.

Poty S, Carter LM, Mandleywala K, Membreno R, Abdel-Atti D, Ragupathi A, Scholz WW, Zeglis BM, Lewis JS.

Clin Cancer Res. 2019 Jan 15;25(2):868-880. doi: 10.1158/1078-0432.CCR-18-1650. Epub 2018 Oct 23.


Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis.

Senders ML, Hernot S, Carlucci G, van de Voort JC, Fay F, Calcagno C, Tang J, Alaarg A, Zhao Y, Ishino S, Palmisano A, Boeykens G, Meerwaldt AE, Sanchez-Gaytan BL, Baxter S, Zendman L, Lobatto ME, Karakatsanis NA, Robson PM, Broisat A, Raes G, Lewis JS, Tsimikas S, Reiner T, Fayad ZA, Devoogdt N, Mulder WJM, Pérez-Medina C.

JACC Cardiovasc Imaging. 2018 Oct 12. pii: S1936-878X(18)30753-8. doi: 10.1016/j.jcmg.2018.07.027. [Epub ahead of print]


Thermal Percolation Threshold and Thermal Properties of Composites with High Loading of Graphene and Boron Nitride Fillers.

Kargar F, Barani Z, Salgado R, Debnath B, Lewis JS, Aytan E, Lake RK, Balandin AA.

ACS Appl Mater Interfaces. 2018 Oct 31;10(43):37555-37565. doi: 10.1021/acsami.8b16616. Epub 2018 Oct 22.


Fluoroquinolone Prophylaxis Selects for Meropenem-nonsusceptible Pseudomonas aeruginosa in Patients With Hematologic Malignancies and Hematopoietic Cell Transplant Recipients.

Hakki M, Humphries RM, Hemarajata P, Tallman GB, Shields RK, Mettus RT, Doi Y, Lewis JS.

Clin Infect Dis. 2019 May 30;68(12):2045-2052. doi: 10.1093/cid/ciy825.


Harnessing Androgen Receptor Pathway Activation for Targeted Alpha Particle Radioimmunotherapy of Breast Cancer.

Thorek DLJ, Ku AT, Mitsiades N, Veach D, Watson PA, Metha D, Strand SE, Sharma SK, Lewis JS, Abou DS, Lilja HG, Larson SM, McDevitt MR, Ulmert D.

Clin Cancer Res. 2019 Jan 15;25(2):881-891. doi: 10.1158/1078-0432.CCR-18-1521. Epub 2018 Sep 25.


Unimicellar hyperstars as multi-antigen cancer nanovaccines displaying clustered epitopes of immunostimulating peptides.

Kakwere H, Ingham ES, Allen R, Mahakian LM, Tam SM, Zhang H, Silvestrini MT, Lewis JS, Ferrara KW.

Biomater Sci. 2018 Nov 1;6(11):2850-2858. doi: 10.1039/c8bm00891d. Epub 2018 Sep 19.


A PET Imaging Strategy for Interrogating Target Engagement and Oncogene Status in Pancreatic Cancer.

Henry KE, Dacek MM, Dilling TR, Caen JD, Fox IL, Evans MJ, Lewis JS.

Clin Cancer Res. 2019 Jan 1;25(1):166-176. doi: 10.1158/1078-0432.CCR-18-1485. Epub 2018 Sep 18.


Leveraging PET to image folate receptor α therapy of an antibody-drug conjugate.

Brand C, Sadique A, Houghton JL, Gangangari K, Ponte JF, Lewis JS, Pillarsetty NVK, Konner JA, Reiner T.

EJNMMI Res. 2018 Aug 28;8(1):87. doi: 10.1186/s13550-018-0437-x.


Clinical Potential of Human Epidermal Growth Factor Receptor 2 and Human Epidermal Growth Factor Receptor 3 Imaging in Breast Cancer.

Henry KE, Ulaner GA, Lewis JS.

PET Clin. 2018 Jul;13(3):423-435. doi: 10.1016/j.cpet.2018.02.010. Review.


Current status of clinical testing for human papillomavirus in oropharyngeal squamous cell carcinoma.

Kim KY, Lewis JS Jr, Chen Z.

J Pathol Clin Res. 2018 Oct;4(4):213-226. doi: 10.1002/cjp2.111. Epub 2018 Sep 18. Review.


Clinical Outcomes of Oral Suspension versus Delayed-Release Tablet Formulations of Posaconazole for Prophylaxis of Invasive Fungal Infections.

Furuno JP, Tallman GB, Noble BN, Bubalo JS, Forrest GN, Lewis JS 2nd, Bienvenida AF, Holmes CA, Weber BR, McGregor JC.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e00893-18. doi: 10.1128/AAC.00893-18. Print 2018 Oct.


Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial.

Souweidane MM, Kramer K, Pandit-Taskar N, Zhou Z, Haque S, Zanzonico P, Carrasquillo JA, Lyashchenko SK, Thakur SB, Donzelli M, Turner RS, Lewis JS, Cheung NV, Larson SM, Dunkel IJ.

Lancet Oncol. 2018 Aug;19(8):1040-1050. doi: 10.1016/S1470-2045(18)30322-X. Epub 2018 Jun 18. Erratum in: Lancet Oncol. 2018 Aug;19(8):e382.


Imaging EGFR and HER3 through 89Zr-labeled MEHD7945A (Duligotuzumab).

McKnight BN, Kuda-Wedagedara ANW, Sevak KK, Abdel-Atti D, Wiesend WN, Ku A, Selvakumar D, Carlin SD, Lewis JS, Viola-Villegas NT.

Sci Rep. 2018 Jun 13;8(1):9043. doi: 10.1038/s41598-018-27454-6.


Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer.

McDevitt MR, Thorek DLJ, Hashimoto T, Gondo T, Veach DR, Sharma SK, Kalidindi TM, Abou DS, Watson PA, Beattie BJ, Timmermand OV, Strand SE, Lewis JS, Scardino PT, Scher HI, Lilja H, Larson SM, Ulmert D.

Nat Commun. 2018 Apr 24;9(1):1629. doi: 10.1038/s41467-018-04107-w.


Reproducibility and Repeatability of Semiquantitative 18F-Fluorodihydrotestosterone Uptake Metrics in Castration-Resistant Prostate Cancer Metastases: A Prospective Multicenter Study.

Vargas HA, Kramer GM, Scott AM, Weickhardt A, Meier AA, Parada N, Beattie BJ, Humm JL, Staton KD, Zanzonico PB, Lyashchenko SK, Lewis JS, Yaqub M, Sosa RE, van den Eertwegh AJ, Davis ID, Ackermann U, Pathmaraj K, Schuit RC, Windhorst AD, Chua S, Weber WA, Larson SM, Scher HI, Lammertsma AA, Hoekstra OS, Morris MJ.

J Nucl Med. 2018 Oct;59(10):1516-1523. doi: 10.2967/jnumed.117.206490. Epub 2018 Apr 6.


PARP-1-Targeted Radiotherapy in Mouse Models of Glioblastoma.

Jannetti SA, Carlucci G, Carney B, Kossatz S, Shenker L, Carter LM, Salinas B, Brand C, Sadique A, Donabedian PL, Cunanan KM, Gönen M, Ponomarev V, Zeglis BM, Souweidane MM, Lewis JS, Weber WA, Humm JL, Reiner T.

J Nucl Med. 2018 Aug;59(8):1225-1233. doi: 10.2967/jnumed.117.205054. Epub 2018 Mar 23.


α-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies-Part 1.

Poty S, Francesconi LC, McDevitt MR, Morris MJ, Lewis JS.

J Nucl Med. 2018 Jun;59(6):878-884. doi: 10.2967/jnumed.116.186338. Epub 2018 Mar 15. Review.

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