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Items: 1 to 50 of 328

1.

Modeling the stem cell hypothesis: Investigating the effects of cancer stem cells and TGF-β on tumor growth.

Elliott SL, Kose E, Lewis AL, Steinfeld AE, Zollinger EA.

Math Biosci Eng. 2019 Aug 7;16(6):7177-7194. doi: 10.3934/mbe.2019360.

2.

Associations between the vaginal microbiome and Candida colonization in women of reproductive age.

Tortelli BA, Lewis WG, Allsworth JE, Member-Meneh N, Foster LR, Reno HE, Peipert JF, Fay JC, Lewis AL.

Am J Obstet Gynecol. 2019 Oct 22. pii: S0002-9378(19)31225-6. doi: 10.1016/j.ajog.2019.10.008. [Epub ahead of print]

PMID:
31654610
3.

Characterization of a Holmium 4,4'-Biphenyldicarboxylate Metal-Organic Framework and Its Potential as a Holmium Carrier System.

Vizuet JP, Lewis AL, McCandless GT, Balkus KJ Jr.

J Nanosci Nanotechnol. 2020 May 1;20(5):3019-3024. doi: 10.1166/jnn.2020.17476.

PMID:
31635642
4.

Vandetanib-eluting Radiopaque Beads: Pharmacokinetics, Safety, and Efficacy in a Rabbit Model of Liver Cancer.

Duran R, Namur J, Pascale F, Czuczman P, Bascal Z, Kilpatrick H, Whomsley R, Ryan S, Lewis AL, Denys A.

Radiology. 2019 Oct 15:190305. doi: 10.1148/radiol.2019190305. [Epub ahead of print]

PMID:
31617791
5.

VEROnA Protocol: A Pilot, Open-Label, Single-Arm, Phase 0, Window-of-Opportunity Study of Vandetanib-Eluting Radiopaque Embolic Beads (BTG-002814) in Patients With Resectable Liver Malignancies.

Beaton L, Tregidgo HFJ, Znati SA, Forsyth S, Clarkson MJ, Bandula S, Chouhan M, Lowe HL, Zaw Thin M, Hague J, Sharma D, Pollok JM, Davidson BR, Raja J, Munneke G, Stuckey DJ, Bascal ZA, Wilde PE, Cooper S, Ryan S, Czuczman P, Boucher E, Hartley JA, Lewis AL, Jansen M, Meyer T, Sharma RA.

JMIR Res Protoc. 2019 Oct 2;8(10):e13696. doi: 10.2196/13696.

6.

Child and adolescent psychiatry training in the USA: current pathways.

Hunt J, Reichenberg J, Lewis AL, Jacobson S.

Eur Child Adolesc Psychiatry. 2019 Sep 12. doi: 10.1007/s00787-019-01402-9. [Epub ahead of print] Review.

PMID:
31515613
7.

Low-dose inoculation of Escherichia coli achieves robust vaginal colonization and results in ascending infection accompanied by severe uterine inflammation in mice.

O'Brien VP, Gilbert NM, Lebratti T, Agarwal K, Foster L, Shin H, Lewis AL.

PLoS One. 2019 Jul 22;14(7):e0219941. doi: 10.1371/journal.pone.0219941. eCollection 2019.

8.

In vitro and ex vivo evaluation of the biological performance of sclerosing foams.

Bottaro E, Paterson JAJ, Quercia L, Zhang X, Hill M, Patel VA, Jones SA, Lewis AL, Millar TM, Carugo D.

Sci Rep. 2019 Jul 8;9(1):9880. doi: 10.1038/s41598-019-46262-0.

9.

Nasal Administration and Plasma Pharmacokinetics of Parathyroid Hormone Peptide PTH 1-34 for the Treatment of Osteoporosis.

Pearson RG, Masud T, Blackshaw E, Naylor A, Hinchcliffe M, Jeffery K, Jordan F, Shabir-Ahmed A, King G, Lewis AL, Illum L, Perkins AC.

Pharmaceutics. 2019 Jun 7;11(6). pii: E265. doi: 10.3390/pharmaceutics11060265.

10.

Physical Vein Models to Quantify the Flow Performance of Sclerosing Foams.

Bottaro E, Paterson J, Zhang X, Hill M, Patel VA, Jones SA, Lewis AL, Millar TM, Carugo D.

Front Bioeng Biotechnol. 2019 May 21;7:109. doi: 10.3389/fbioe.2019.00109. eCollection 2019.

11.

Predicting pharmacokinetic behaviour of drug release from drug-eluting embolization beads using in vitro elution methods.

Hagan A, Caine M, Press C, Macfarlane WM, Phillips G, Lloyd AW, Czuczman P, Kilpatrick H, Bascal Z, Tang Y, Garcia P, Lewis AL.

Eur J Pharm Sci. 2019 Aug 1;136:104943. doi: 10.1016/j.ejps.2019.05.021. Epub 2019 May 29.

12.

Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification.

Parsons MT, Tudini E, Li H, Hahnen E, Wappenschmidt B, Feliubadaló L, Aalfs CM, Agata S, Aittomäki K, Alducci E, Alonso-Cerezo MC, Arnold N, Auber B, Austin R, Azzollini J, Balmaña J, Barbieri E, Bartram CR, Blanco A, Blümcke B, Bonache S, Bonanni B, Borg Å, Bortesi B, Brunet J, Bruzzone C, Bucksch K, Cagnoli G, Caldés T, Caliebe A, Caligo MA, Calvello M, Capone GL, Caputo SM, Carnevali I, Carrasco E, Caux-Moncoutier V, Cavalli P, Cini G, Clarke EM, Concolino P, Cops EJ, Cortesi L, Couch FJ, Darder E, de la Hoya M, Dean M, Debatin I, Del Valle J, Delnatte C, Derive N, Diez O, Ditsch N, Domchek SM, Dutrannoy V, Eccles DM, Ehrencrona H, Enders U, Evans DG, Farra C, Faust U, Felbor U, Feroce I, Fine M, Foulkes WD, Galvao HCR, Gambino G, Gehrig A, Gensini F, Gerdes AM, Germani A, Giesecke J, Gismondi V, Gómez C, Gómez Garcia EB, González S, Grau E, Grill S, Gross E, Guerrieri-Gonzaga A, Guillaud-Bataille M, Gutiérrez-Enríquez S, Haaf T, Hackmann K, Hansen TVO, Harris M, Hauke J, Heinrich T, Hellebrand H, Herold KN, Honisch E, Horvath J, Houdayer C, Hübbel V, Iglesias S, Izquierdo A, James PA, Janssen LAM, Jeschke U, Kaulfuß S, Keupp K, Kiechle M, Kölbl A, Krieger S, Kruse TA, Kvist A, Lalloo F, Larsen M, Lattimore VL, Lautrup C, Ledig S, Leinert E, Lewis AL, Lim J, Loeffler M, López-Fernández A, Lucci-Cordisco E, Maass N, Manoukian S, Marabelli M, Matricardi L, Meindl A, Michelli RD, Moghadasi S, Moles-Fernández A, Montagna M, Montalban G, Monteiro AN, Montes E, Mori L, Moserle L, Müller CR, Mundhenke C, Naldi N, Nathanson KL, Navarro M, Nevanlinna H, Nichols CB, Niederacher D, Nielsen HR, Ong KR, Pachter N, Palmero EI, Papi L, Pedersen IS, Peissel B, Perez-Segura P, Pfeifer K, Pineda M, Pohl-Rescigno E, Poplawski NK, Porfirio B, Quante AS, Ramser J, Reis RM, Revillion F, Rhiem K, Riboli B, Ritter J, Rivera D, Rofes P, Rump A, Salinas M, Sánchez de Abajo AM, Schmidt G, Schoenwiese U, Seggewiß J, Solanes A, Steinemann D, Stiller M, Stoppa-Lyonnet D, Sullivan KJ, Susman R, Sutter C, Tavtigian SV, Teo SH, Teulé A, Thomassen M, Tibiletti MG, Tischkowitz M, Tognazzo S, Toland AE, Tornero E, Törngren T, Torres-Esquius S, Toss A, Trainer AH, Tucker KM, van Asperen CJ, van Mackelenbergh MT, Varesco L, Vargas-Parra G, Varon R, Vega A, Velasco Á, Vesper AS, Viel A, Vreeswijk MPG, Wagner SA, Waha A, Walker LC, Walters RJ, Wang-Gohrke S, Weber BHF, Weichert W, Wieland K, Wiesmüller L, Witzel I, Wöckel A, Woodward ER, Zachariae S, Zampiga V, Zeder-Göß C, Investigators K, Lázaro C, De Nicolo A, Radice P, Engel C, Schmutzler RK, Goldgar DE, Spurdle AB.

Hum Mutat. 2019 Sep;40(9):1557-1578. doi: 10.1002/humu.23818.

13.

Clinical and Patient-reported Outcome Measures in Men Referred for Consideration of Surgery to Treat Lower Urinary Tract Symptoms: Baseline Results and Diagnostic Findings of the Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM).

Lewis AL, Young GJ, Abrams P, Blair PS, Chapple C, Glazener CMA, Horwood J, McGrath JS, Noble S, Taylor GT, Ito H, Belal M, Davies MC, Dickinson AJ, Foley CL, Foley S, Fulford S, Gammal MM, Garthwaite M, Harris MRE, Ilie PC, Jones R, Sabbagh S, Mason RG, McLarty E, Mishra V, Mom J, Morley R, Natale S, Nitkunan T, Page T, Payne D, Rashid TG, Saeb-Parsy K, Sandhu SS, Simoes A, Singh G, Sullivan M, Tempest HV, Viswanath S, Walker RMH, Lane JA, Drake MJ.

Eur Urol Focus. 2019 May;5(3):340-350. doi: 10.1016/j.euf.2019.04.006. Epub 2019 Apr 30.

PMID:
31047905
14.

Toward a better understanding of the mechanism of action for intra-arterial delivery of irinotecan from DC Bead(TM) (DEBIRI).

Lewis AL, Hall B.

Future Oncol. 2019 Jun;15(17):2053-2068. doi: 10.2217/fon-2019-0071. Epub 2019 Apr 3.

15.

Transition from a 1D Coordination Polymer to a Mixed-Linker Layered MOF.

Vizuet JP, Howlett TS, Lewis AL, Chroust ZD, McCandless GT, Balkus KJ Jr.

Inorg Chem. 2019 Apr 15;58(8):5031-5041. doi: 10.1021/acs.inorgchem.9b00077. Epub 2019 Mar 29.

PMID:
30924648
16.

Covert pathogenesis: Transient exposures to microbes as triggers of disease.

Gilbert NM, Lewis AL.

PLoS Pathog. 2019 Mar 28;15(3):e1007586. doi: 10.1371/journal.ppat.1007586. eCollection 2019 Mar. No abstract available.

17.

Identification and characterization of NanH2 and NanH3, enzymes responsible for sialidase activity in the vaginal bacterium Gardnerella vaginalis.

Robinson LS, Schwebke J, Lewis WG, Lewis AL.

J Biol Chem. 2019 Apr 5;294(14):5230-5245. doi: 10.1074/jbc.RA118.006221. Epub 2019 Feb 5.

PMID:
30723162
18.

Gardnerella vaginalis and Prevotella bivia Trigger Distinct and Overlapping Phenotypes in a Mouse Model of Bacterial Vaginosis.

Gilbert NM, Lewis WG, Li G, Sojka DK, Lubin JB, Lewis AL.

J Infect Dis. 2019 Aug 30;220(7):1099-1108. doi: 10.1093/infdis/jiy704.

PMID:
30715405
19.

Association between obesity and bacterial vaginosis as assessed by Nugent score.

Brookheart RT, Lewis WG, Peipert JF, Lewis AL, Allsworth JE.

Am J Obstet Gynecol. 2019 May;220(5):476.e1-476.e11. doi: 10.1016/j.ajog.2019.01.229. Epub 2019 Jan 29.

PMID:
30707966
20.

Characterizing Drug-Polymer Bead Interactions Using Isothermal Titration Calorimetry.

Swaine TS, Garcia P, Tang Y, Lewis AL, Parkes G, Waters LJ.

J Pharm Sci. 2019 May;108(5):1772-1778. doi: 10.1016/j.xphs.2018.12.009. Epub 2018 Dec 19.

21.

Structural and functional characterization of a modified legionaminic acid involved in glycosylation of a bacterial lipopolysaccharide.

McDonald ND, DeMeester KE, Lewis AL, Grimes CL, Boyd EF.

J Biol Chem. 2018 Dec 7;293(49):19113-19126. doi: 10.1074/jbc.RA118.004966. Epub 2018 Oct 12.

PMID:
30315110
22.

Recommendations for conducting invasive urodynamics for men with lower urinary tract symptoms: Qualitative interview findings from a large randomized controlled trial (UPSTREAM).

Selman LE, Ochieng CA, Lewis AL, Drake MJ, Horwood J.

Neurourol Urodyn. 2019 Jan;38(1):320-329. doi: 10.1002/nau.23855. Epub 2018 Oct 12.

23.

Mapping Drug Dose Distribution on CT Images Following Transarterial Chemoembolization with Radiopaque Drug-Eluting Beads in a Rabbit Tumor Model.

Mikhail AS, Pritchard WF, Negussie AH, Krishnasamy VP, Amchin DB, Thompson JG, Wakim PG, Woods D, Bakhutashvili I, Esparza-Trujillo JA, Karanian JW, Willis SL, Lewis AL, Levy EB, Wood BJ.

Radiology. 2018 Nov;289(2):396-404. doi: 10.1148/radiol.2018172571. Epub 2018 Aug 14.

24.

Corrigendum to "In vitro and preclinical assessment of an intranasal spray formulation of parathyroid hormone PTH 1-34 for the treatment of osteoporosis" [Int. J. Pharm. 535 (2018) 113-119].

Williams AJ, Jordan F, King G, Lewis AL, Illum L, Masud T, Perkins AC, Pearson RG.

Int J Pharm. 2018 Aug 25;547(1-2):667. doi: 10.1016/j.ijpharm.2018.06.045. Epub 2018 Jul 5. No abstract available.

PMID:
29983223
25.

Bench-to-clinic development of imageable drug-eluting embolization beads: finding the balance.

Lewis AL, Willis SL, Dreher MR, Tang Y, Ashrafi K, Wood BJ, Levy EB, Sharma KV, Negussie AH, Mikhail AS.

Future Oncol. 2018 Nov;14(26):2741-2760. doi: 10.2217/fon-2018-0196. Epub 2018 Jun 26. Review.

26.

Distribution and Detection of Radiopaque Beads after Hepatic Transarterial Embolization in Swine: Cone-Beam CT versus MicroCT.

Thompson JG, van der Sterren W, Bakhutashvili I, van der Bom IM, Radaelli AG, Karanian JW, Esparza-Trujillo J, Woods DL, Lewis AL, Wood BJ, Pritchard WF.

J Vasc Interv Radiol. 2018 Apr;29(4):568-574. doi: 10.1016/j.jvir.2017.11.011. Epub 2018 Mar 2.

27.

Correction to: The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo.

Lawton JM, Habib M, Ma B, Brooks RA, Best SM, Lewis AL, Rushton N, Bonfield W.

J Mater Sci Mater Med. 2018 Feb 22;29(3):26. doi: 10.1007/s10856-018-6028-6.

28.

Comparison of microsphere penetration with LC Bead LUMI™ versus other commercial microspheres.

Caine M, Zhang X, Hill M, Guo W, Ashrafi K, Bascal Z, Kilpatrick H, Dunn A, Grey D, Bushby R, Bushby A, Willis SL, Dreher MR, Lewis AL.

J Mech Behav Biomed Mater. 2018 Feb;78:46-55. doi: 10.1016/j.jmbbm.2017.10.034. Epub 2017 Oct 31.

29.

In vitro and preclinical assessment of an intranasal spray formulation of parathyroid hormone PTH 1-34 for the treatment of osteoporosis.

Williams AJ, Jordan F, King G, Lewis AL, Illum L, Masud T, Perkins AC, Pearson RG.

Int J Pharm. 2018 Jan 15;535(1-2):113-119. doi: 10.1016/j.ijpharm.2017.10.029. Epub 2017 Oct 14. Erratum in: Int J Pharm. 2018 Aug 25;547(1-2):667.

PMID:
29038066
30.

Statistical analysis plan for the Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM).

Young GJ, Lewis AL, Lane JA, Winton HL, Drake MJ, Blair PS.

Trials. 2017 Oct 3;18(1):455. doi: 10.1186/s13063-017-2206-y.

31.

Inhibition of the receptor for advanced glycation end-products (RAGE) protects from secondhand smoke (SHS)-induced intrauterine growth restriction IUGR in mice.

Lewis JB, Mejia C, Jordan C, Monson TD, Bodine JS, Dunaway TM, Egbert KM, Lewis AL, Wright TJ, Ogden KC, Broberg DS, Hall PD, Nelson SM, Hirschi KM, Reynolds PR, Arroyo JA.

Cell Tissue Res. 2017 Dec;370(3):513-521. doi: 10.1007/s00441-017-2691-z. Epub 2017 Sep 26.

PMID:
28948356
32.

The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo.

Lawton JM, Habib M, Ma B, Brooks RA, Best SM, Lewis AL, Rushton N, Bonfield W.

J Mater Sci Mater Med. 2017 Aug 17;28(9):144. doi: 10.1007/s10856-017-5958-8. Erratum in: J Mater Sci Mater Med. 2018 Feb 22;29(3):26.

33.

Vandetanib-eluting Radiopaque Beads: In vivo Pharmacokinetics, Safety and Toxicity Evaluation following Swine Liver Embolization.

Denys A, Czuczman P, Grey D, Bascal Z, Whomsley R, Kilpatrick H, Lewis AL.

Theranostics. 2017 Jun 1;7(8):2164-2176. doi: 10.7150/thno.19652. eCollection 2017.

34.

Development of MPC-DPA polymeric nanoparticle systems for inhalation drug delivery applications.

Elzhry Elyafi AK, Standen G, Meikle ST, Lewis AL, Salvage JP.

Eur J Pharm Sci. 2017 Aug 30;106:362-380. doi: 10.1016/j.ejps.2017.06.023. Epub 2017 Jun 19.

PMID:
28629803
35.

Relationship between nugent score and vaginal epithelial exfoliation.

Amegashie CP, Gilbert NM, Peipert JF, Allsworth JE, Lewis WG, Lewis AL.

PLoS One. 2017 May 31;12(5):e0177797. doi: 10.1371/journal.pone.0177797. eCollection 2017.

36.

Hypoxia as a target for drug combination therapy of liver cancer.

Bowyer C, Lewis AL, Lloyd AW, Phillips GJ, Macfarlane WM.

Anticancer Drugs. 2017 Aug;28(7):771-780. doi: 10.1097/CAD.0000000000000516.

37.

The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans.

Robinson LS, Lewis WG, Lewis AL.

J Biol Chem. 2017 Jul 14;292(28):11861-11872. doi: 10.1074/jbc.M116.769232. Epub 2017 May 19.

38.

Nanostructured DPA-MPC-DPA triblock copolymer gel for controlled drug release of ketoprofen and spironolactone.

Azmy B, Standen G, Kristova P, Flint A, Lewis AL, Salvage JP.

J Pharm Pharmacol. 2017 Aug;69(8):978-990. doi: 10.1111/jphp.12733. Epub 2017 May 7.

PMID:
28480594
39.

Human milk oligosaccharides inhibit growth of group B Streptococcus.

Lin AE, Autran CA, Szyszka A, Escajadillo T, Huang M, Godula K, Prudden AR, Boons GJ, Lewis AL, Doran KS, Nizet V, Bode L.

J Biol Chem. 2017 Jul 7;292(27):11243-11249. doi: 10.1074/jbc.M117.789974. Epub 2017 Apr 17.

40.

Towards Hypoxia-responsive Drug-eluting Embolization Beads.

Ashrafi K, Heaysman CL, Phillips GJ, Lloyd AW, Lewis AL.

Int J Pharm. 2017 May 30;524(1-2):226-237. doi: 10.1016/j.ijpharm.2017.03.084. Epub 2017 Mar 31.

41.

Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease.

Gilbert NM, O'Brien VP, Lewis AL.

PLoS Pathog. 2017 Mar 30;13(3):e1006238. doi: 10.1371/journal.ppat.1006238. eCollection 2017 Mar.

42.

Review of the Development of Methods for Characterization of Microspheres for Use in Embolotherapy: Translating Bench to Cathlab.

Caine M, Carugo D, Zhang X, Hill M, Dreher MR, Lewis AL.

Adv Healthc Mater. 2017 May;6(9). doi: 10.1002/adhm.201601291. Epub 2017 Feb 20. Review.

PMID:
28218823
43.

Unusual behaviour induced by phase separation in hydrogel microspheres.

Heaysman CL, Philips GJ, Lloyd AW, Lewis AL.

Acta Biomater. 2017 Apr 15;53:190-198. doi: 10.1016/j.actbio.2017.02.013. Epub 2017 Feb 13.

44.

Characterization of a novel intrinsically radiopaque Drug-eluting Bead for image-guided therapy: DC Bead LUMI™.

Ashrafi K, Tang Y, Britton H, Domenge O, Blino D, Bushby AJ, Shuturminska K, den Hartog M, Radaelli A, Negussie AH, Mikhail AS, Woods DL, Krishnasamy V, Levy EB, Wood BJ, Willis SL, Dreher MR, Lewis AL.

J Control Release. 2017 Mar 28;250:36-47. doi: 10.1016/j.jconrel.2017.02.001. Epub 2017 Feb 8.

45.

Preparation and characterisation of vandetanib-eluting radiopaque beads for locoregional treatment of hepatic malignancies.

Hagan A, Phillips GJ, Macfarlane WM, Lloyd AW, Czuczman P, Lewis AL.

Eur J Pharm Sci. 2017 Apr 1;101:22-30. doi: 10.1016/j.ejps.2017.01.033. Epub 2017 Jan 27.

46.

Nanotribological Investigation of Polymer Brushes with Lithographically Defined and Systematically Varying Grafting Densities.

Zhang ZJ, Moxey M, Alswieleh A, Armes SP, Lewis AL, Geoghegan M, Leggett GJ.

Langmuir. 2017 Jan 24;33(3):706-713. doi: 10.1021/acs.langmuir.6b04022. Epub 2017 Jan 12.

47.

A Review on Phosphorylcholine-Coated Stents.

Lewis AL, Stratford PW.

J Long Term Eff Med Implants. 2017;27(2-4):233-252. doi: 10.1615/JLongTermEffMedImplants.v27.i2-4.80. Review.

PMID:
29773041
48.

Combined MSC and GLP-1 Therapy Modulates Collagen Remodeling and Apoptosis following Myocardial Infarction.

Wright EJ, Hodson NW, Sherratt MJ, Kassem M, Lewis AL, Wallrapp C, Malik N, Holt CM.

Stem Cells Int. 2016;2016:7357096. doi: 10.1155/2016/7357096. Epub 2016 Nov 28.

49.

Cigarette smoke and decreased oxygen tension inhibit pulmonary claudin-6 expression.

Jimenez FR, Lewis JB, Belgique ST, Milner DC, Lewis AL, Dunaway TM, Egbert KM, Winden DR, Arroyo JA, Reynolds PR.

Exp Lung Res. 2016 Oct - Dec;42(8-10):440-452. doi: 10.1080/01902148.2016.1261309. Epub 2016 Dec 16.

PMID:
27982694
50.

A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease.

O'Brien VP, Hannan TJ, Yu L, Livny J, Roberson ED, Schwartz DJ, Souza S, Mendelsohn CL, Colonna M, Lewis AL, Hultgren SJ.

Nat Microbiol. 2016 Oct 31;2:16196. doi: 10.1038/nmicrobiol.2016.196.

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