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Toward a better understanding of the mechanism of action for intra-arterial delivery of irinotecan from DC Bead(TM) (DEBIRI).

Lewis AL, Hall B.

Future Oncol. 2019 Apr 3. doi: 10.2217/fon-2019-0071. [Epub ahead of print]


Transition from a 1D Coordination Polymer to a Mixed-Linker Layered MOF.

Vizuet JP, Howlett TS, Lewis AL, Chroust ZD, McCandless GT, Balkus KJ Jr.

Inorg Chem. 2019 Apr 15;58(8):5031-5041. doi: 10.1021/acs.inorgchem.9b00077. Epub 2019 Mar 29.


Covert pathogenesis: Transient exposures to microbes as triggers of disease.

Gilbert NM, Lewis AL.

PLoS Pathog. 2019 Mar 28;15(3):e1007586. doi: 10.1371/journal.ppat.1007586. eCollection 2019 Mar. No abstract available.


Identification and characterization of NanH2 and NanH3, enzymes responsible for sialidase activity in the vaginal bacterium Gardnerella vaginalis.

Robinson LS, Schwebke J, Lewis WG, Lewis AL.

J Biol Chem. 2019 Apr 5;294(14):5230-5245. doi: 10.1074/jbc.RA118.006221. Epub 2019 Feb 5.


Gardnerella vaginalis and Prevotella bivia Trigger Distinct and Overlapping Phenotypes in a Mouse Model of Bacterial Vaginosis.

Gilbert NM, Lewis WG, Li G, Sojka DK, Lubin JB, Lewis AL.

J Infect Dis. 2019 Feb 1. doi: 10.1093/infdis/jiy704. [Epub ahead of print]


Association between obesity and bacterial vaginosis as assessed by Nugent score.

Brookheart RT, Lewis WG, Peipert JF, Lewis AL, Allsworth JE.

Am J Obstet Gynecol. 2019 Jan 29. pii: S0002-9378(19)30283-2. doi: 10.1016/j.ajog.2019.01.229. [Epub ahead of print]


Characterizing Drug-Polymer Bead Interactions Using Isothermal Titration Calorimetry.

Swaine TS, Garcia P, Tang Y, Lewis AL, Parkes G, Waters LJ.

J Pharm Sci. 2018 Dec 19. pii: S0022-3549(18)30805-0. doi: 10.1016/j.xphs.2018.12.009. [Epub ahead of print]


Structural and functional characterization of a modified legionaminic acid involved in glycosylation of a bacterial lipopolysaccharide.

McDonald ND, DeMeester KE, Lewis AL, Grimes CL, Boyd EF.

J Biol Chem. 2018 Dec 7;293(49):19113-19126. doi: 10.1074/jbc.RA118.004966. Epub 2018 Oct 12.


Recommendations for conducting invasive urodynamics for men with lower urinary tract symptoms: Qualitative interview findings from a large randomized controlled trial (UPSTREAM).

Selman LE, Ochieng CA, Lewis AL, Drake MJ, Horwood J.

Neurourol Urodyn. 2019 Jan;38(1):320-329. doi: 10.1002/nau.23855. Epub 2018 Oct 12.


Mapping Drug Dose Distribution on CT Images Following Transarterial Chemoembolization with Radiopaque Drug-Eluting Beads in a Rabbit Tumor Model.

Mikhail AS, Pritchard WF, Negussie AH, Krishnasamy VP, Amchin DB, Thompson JG, Wakim PG, Woods D, Bakhutashvili I, Esparza-Trujillo JA, Karanian JW, Willis SL, Lewis AL, Levy EB, Wood BJ.

Radiology. 2018 Nov;289(2):396-404. doi: 10.1148/radiol.2018172571. Epub 2018 Aug 14.


Corrigendum to "In vitro and preclinical assessment of an intranasal spray formulation of parathyroid hormone PTH 1-34 for the treatment of osteoporosis" [Int. J. Pharm. 535 (2018) 113-119].

Williams AJ, Jordan F, King G, Lewis AL, Illum L, Masud T, Perkins AC, Pearson RG.

Int J Pharm. 2018 Aug 25;547(1-2):667. doi: 10.1016/j.ijpharm.2018.06.045. Epub 2018 Jul 5. No abstract available.


Bench-to-clinic development of imageable drug-eluting embolization beads: finding the balance.

Lewis AL, Willis SL, Dreher MR, Tang Y, Ashrafi K, Wood BJ, Levy EB, Sharma KV, Negussie AH, Mikhail AS.

Future Oncol. 2018 Nov;14(26):2741-2760. doi: 10.2217/fon-2018-0196. Epub 2018 Jun 26. Review.


Distribution and Detection of Radiopaque Beads after Hepatic Transarterial Embolization in Swine: Cone-Beam CT versus MicroCT.

Thompson JG, van der Sterren W, Bakhutashvili I, van der Bom IM, Radaelli AG, Karanian JW, Esparza-Trujillo J, Woods DL, Lewis AL, Wood BJ, Pritchard WF.

J Vasc Interv Radiol. 2018 Apr;29(4):568-574. doi: 10.1016/j.jvir.2017.11.011. Epub 2018 Mar 2.


Correction to: The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo.

Lawton JM, Habib M, Ma B, Brooks RA, Best SM, Lewis AL, Rushton N, Bonfield W.

J Mater Sci Mater Med. 2018 Feb 22;29(3):26. doi: 10.1007/s10856-018-6028-6.


Comparison of microsphere penetration with LC Bead LUMI™ versus other commercial microspheres.

Caine M, Zhang X, Hill M, Guo W, Ashrafi K, Bascal Z, Kilpatrick H, Dunn A, Grey D, Bushby R, Bushby A, Willis SL, Dreher MR, Lewis AL.

J Mech Behav Biomed Mater. 2018 Feb;78:46-55. doi: 10.1016/j.jmbbm.2017.10.034. Epub 2017 Oct 31.


In vitro and preclinical assessment of an intranasal spray formulation of parathyroid hormone PTH 1-34 for the treatment of osteoporosis.

Williams AJ, Jordan F, King G, Lewis AL, Illum L, Masud T, Perkins AC, Pearson RG.

Int J Pharm. 2018 Jan 15;535(1-2):113-119. doi: 10.1016/j.ijpharm.2017.10.029. Epub 2017 Oct 14. Erratum in: Int J Pharm. 2018 Aug 25;547(1-2):667.


Statistical analysis plan for the Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM).

Young GJ, Lewis AL, Lane JA, Winton HL, Drake MJ, Blair PS.

Trials. 2017 Oct 3;18(1):455. doi: 10.1186/s13063-017-2206-y.


Inhibition of the receptor for advanced glycation end-products (RAGE) protects from secondhand smoke (SHS)-induced intrauterine growth restriction IUGR in mice.

Lewis JB, Mejia C, Jordan C, Monson TD, Bodine JS, Dunaway TM, Egbert KM, Lewis AL, Wright TJ, Ogden KC, Broberg DS, Hall PD, Nelson SM, Hirschi KM, Reynolds PR, Arroyo JA.

Cell Tissue Res. 2017 Dec;370(3):513-521. doi: 10.1007/s00441-017-2691-z. Epub 2017 Sep 26.


The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo.

Lawton JM, Habib M, Ma B, Brooks RA, Best SM, Lewis AL, Rushton N, Bonfield W.

J Mater Sci Mater Med. 2017 Aug 17;28(9):144. doi: 10.1007/s10856-017-5958-8. Erratum in: J Mater Sci Mater Med. 2018 Feb 22;29(3):26.


Vandetanib-eluting Radiopaque Beads: In vivo Pharmacokinetics, Safety and Toxicity Evaluation following Swine Liver Embolization.

Denys A, Czuczman P, Grey D, Bascal Z, Whomsley R, Kilpatrick H, Lewis AL.

Theranostics. 2017 Jun 1;7(8):2164-2176. doi: 10.7150/thno.19652. eCollection 2017.


Development of MPC-DPA polymeric nanoparticle systems for inhalation drug delivery applications.

Elzhry Elyafi AK, Standen G, Meikle ST, Lewis AL, Salvage JP.

Eur J Pharm Sci. 2017 Aug 30;106:362-380. doi: 10.1016/j.ejps.2017.06.023. Epub 2017 Jun 19.


Relationship between nugent score and vaginal epithelial exfoliation.

Amegashie CP, Gilbert NM, Peipert JF, Allsworth JE, Lewis WG, Lewis AL.

PLoS One. 2017 May 31;12(5):e0177797. doi: 10.1371/journal.pone.0177797. eCollection 2017.


Hypoxia as a target for drug combination therapy of liver cancer.

Bowyer C, Lewis AL, Lloyd AW, Phillips GJ, Macfarlane WM.

Anticancer Drugs. 2017 Aug;28(7):771-780. doi: 10.1097/CAD.0000000000000516.


The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans.

Robinson LS, Lewis WG, Lewis AL.

J Biol Chem. 2017 Jul 14;292(28):11861-11872. doi: 10.1074/jbc.M116.769232. Epub 2017 May 19.


Nanostructured DPA-MPC-DPA triblock copolymer gel for controlled drug release of ketoprofen and spironolactone.

Azmy B, Standen G, Kristova P, Flint A, Lewis AL, Salvage JP.

J Pharm Pharmacol. 2017 Aug;69(8):978-990. doi: 10.1111/jphp.12733. Epub 2017 May 7.


Human milk oligosaccharides inhibit growth of group B Streptococcus.

Lin AE, Autran CA, Szyszka A, Escajadillo T, Huang M, Godula K, Prudden AR, Boons GJ, Lewis AL, Doran KS, Nizet V, Bode L.

J Biol Chem. 2017 Jul 7;292(27):11243-11249. doi: 10.1074/jbc.M117.789974. Epub 2017 Apr 17.


Towards Hypoxia-responsive Drug-eluting Embolization Beads.

Ashrafi K, Heaysman CL, Phillips GJ, Lloyd AW, Lewis AL.

Int J Pharm. 2017 May 30;524(1-2):226-237. doi: 10.1016/j.ijpharm.2017.03.084. Epub 2017 Mar 31.


Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease.

Gilbert NM, O'Brien VP, Lewis AL.

PLoS Pathog. 2017 Mar 30;13(3):e1006238. doi: 10.1371/journal.ppat.1006238. eCollection 2017 Mar.


Review of the Development of Methods for Characterization of Microspheres for Use in Embolotherapy: Translating Bench to Cathlab.

Caine M, Carugo D, Zhang X, Hill M, Dreher MR, Lewis AL.

Adv Healthc Mater. 2017 May;6(9). doi: 10.1002/adhm.201601291. Epub 2017 Feb 20. Review.


Unusual behaviour induced by phase separation in hydrogel microspheres.

Heaysman CL, Philips GJ, Lloyd AW, Lewis AL.

Acta Biomater. 2017 Apr 15;53:190-198. doi: 10.1016/j.actbio.2017.02.013. Epub 2017 Feb 13.


Characterization of a novel intrinsically radiopaque Drug-eluting Bead for image-guided therapy: DC Bead LUMI™.

Ashrafi K, Tang Y, Britton H, Domenge O, Blino D, Bushby AJ, Shuturminska K, den Hartog M, Radaelli A, Negussie AH, Mikhail AS, Woods DL, Krishnasamy V, Levy EB, Wood BJ, Willis SL, Dreher MR, Lewis AL.

J Control Release. 2017 Mar 28;250:36-47. doi: 10.1016/j.jconrel.2017.02.001. Epub 2017 Feb 8.


Preparation and characterisation of vandetanib-eluting radiopaque beads for locoregional treatment of hepatic malignancies.

Hagan A, Phillips GJ, Macfarlane WM, Lloyd AW, Czuczman P, Lewis AL.

Eur J Pharm Sci. 2017 Apr 1;101:22-30. doi: 10.1016/j.ejps.2017.01.033. Epub 2017 Jan 27.


Nanotribological Investigation of Polymer Brushes with Lithographically Defined and Systematically Varying Grafting Densities.

Zhang ZJ, Moxey M, Alswieleh A, Armes SP, Lewis AL, Geoghegan M, Leggett GJ.

Langmuir. 2017 Jan 24;33(3):706-713. doi: 10.1021/acs.langmuir.6b04022. Epub 2017 Jan 12.


A Review on Phosphorylcholine-Coated Stents.

Lewis AL, Stratford PW.

J Long Term Eff Med Implants. 2017;27(2-4):233-252. doi: 10.1615/JLongTermEffMedImplants.v27.i2-4.80.


Combined MSC and GLP-1 Therapy Modulates Collagen Remodeling and Apoptosis following Myocardial Infarction.

Wright EJ, Hodson NW, Sherratt MJ, Kassem M, Lewis AL, Wallrapp C, Malik N, Holt CM.

Stem Cells Int. 2016;2016:7357096. doi: 10.1155/2016/7357096. Epub 2016 Nov 28.


Cigarette smoke and decreased oxygen tension inhibit pulmonary claudin-6 expression.

Jimenez FR, Lewis JB, Belgique ST, Milner DC, Lewis AL, Dunaway TM, Egbert KM, Winden DR, Arroyo JA, Reynolds PR.

Exp Lung Res. 2016 Oct - Dec;42(8-10):440-452. doi: 10.1080/01902148.2016.1261309. Epub 2016 Dec 16.


A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease.

O'Brien VP, Hannan TJ, Yu L, Livny J, Roberson ED, Schwartz DJ, Souza S, Mendelsohn CL, Colonna M, Lewis AL, Hultgren SJ.

Nat Microbiol. 2016 Oct 31;2:16196. doi: 10.1038/nmicrobiol.2016.196.


Up-Regulation of Claudin-6 in the Distal Lung Impacts Secondhand Smoke-Induced Inflammation.

Lewis JB, Milner DC, Lewis AL, Dunaway TM, Egbert KM, Albright SC, Merrell BJ, Monson TD, Broberg DS, Gassman JR, Thomas DB, Arroyo JA, Reynolds PR.

Int J Environ Res Public Health. 2016 Oct 17;13(10). pii: E1018.


A New Catalog of Microbiological Tools for Women's Infectious Disease Research.

Lewis AL, Lewis WG.

Genome Announc. 2016 Sep 29;4(5). pii: e00890-16. doi: 10.1128/genomeA.00890-16.


Genome Sequences of Nine Gram-Negative Vaginal Bacterial Isolates.

Deitzler GE, Ruiz MJ, Lu W, Weimer C, Park S, Robinson LS, Hallsworth-Pepin K, Wollam A, Mitreva M, Lewis WG, Lewis AL.

Genome Announc. 2016 Sep 29;4(5). pii: e00889-16. doi: 10.1128/genomeA.00889-16.


Genome Sequences of 14 Firmicutes Strains Isolated from the Human Vagina.

Deitzler GE, Ruiz MJ, Weimer C, Park S, Robinson L, Hallsworth-Pepin K, Wollam A, Mitreva M, Lewis AL, Lewis WG.

Genome Announc. 2016 Sep 29;4(5). pii: e00888-16. doi: 10.1128/genomeA.00888-16.


Genome Sequences of 11 Human Vaginal Actinobacteria Strains.

Lewis AL, Deitzler GE, Ruiz MJ, Weimer C, Park S, Robinson LS, Hallsworth-Pepin K, Wollam A, Mitreva M, Lewis WG.

Genome Announc. 2016 Sep 29;4(5). pii: e00887-16. doi: 10.1128/genomeA.00887-16.


Genome Sequences of 12 Bacterial Isolates Obtained from the Urine of Pregnant Women.

Weimer CM, Deitzler GE, Robinson LS, Park S, Hallsworth-Pepin K, Wollam A, Mitreva M, Lewis WG, Lewis AL.

Genome Announc. 2016 Sep 29;4(5). pii: e00882-16. doi: 10.1128/genomeA.00882-16.


Genome Sequences of 15 Gardnerella vaginalis Strains Isolated from the Vaginas of Women with and without Bacterial Vaginosis.

Robinson LS, Perry J, Lek S, Wollam A, Sodergren E, Weinstock G, Lewis WG, Lewis AL.

Genome Announc. 2016 Sep 29;4(5). pii: e00879-16. doi: 10.1128/genomeA.00879-16.


Impact of Yttrium-90 Microsphere Density, Flow Dynamics, and Administration Technique on Spatial Distribution: Analysis Using an In Vitro Model.

Caine M, McCafferty MS, McGhee S, Garcia P, Mullett WM, Zhang X, Hill M, Dreher MR, Lewis AL.

J Vasc Interv Radiol. 2017 Feb;28(2):260-268.e2. doi: 10.1016/j.jvir.2016.07.001. Epub 2016 Sep 15.


Discovery and characterization of de novo sialic acid biosynthesis in the phylum Fusobacterium.

Lewis AL, Robinson LS, Agarwal K, Lewis WG.

Glycobiology. 2016 Oct;26(10):1107-1119. doi: 10.1093/glycob/cww068. Epub 2016 Sep 9.


Evaluation of ion exchange processes in drug-eluting embolization beads by use of an improved flow-through elution method.

Swaine T, Tang Y, Garcia P, John J, Waters LJ, Lewis AL.

Eur J Pharm Sci. 2016 Oct 10;93:351-9. doi: 10.1016/j.ejps.2016.08.020. Epub 2016 Aug 12.


How the Principles of Improvisational Theater Can Set Your Educational Potential Free!

Lewis AL.

Acad Psychiatry. 2016 Dec;40(6):953-955. Epub 2016 Jul 29. No abstract available.


Long-term biocompatibility, imaging appearance and tissue effects associated with delivery of a novel radiopaque embolization bead for image-guided therapy.

Sharma KV, Bascal Z, Kilpatrick H, Ashrafi K, Willis SL, Dreher MR, Lewis AL.

Biomaterials. 2016 Oct;103:293-304. doi: 10.1016/j.biomaterials.2016.06.064. Epub 2016 Jul 5.


Evolutionary inactivation of a sialidase in group B Streptococcus.

Yamaguchi M, Hirose Y, Nakata M, Uchiyama S, Yamaguchi Y, Goto K, Sumitomo T, Lewis AL, Kawabata S, Nizet V.

Sci Rep. 2016 Jun 29;6:28852. doi: 10.1038/srep28852.

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