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Items: 1 to 50 of 133

1.

Novel triazine dimers with potent antitrypanosomal activity.

Venkatraj M, Salado IG, Heeres J, Joossens J, Lewi PJ, Caljon G, Maes L, Van der Veken P, Augustyns K.

Eur J Med Chem. 2018 Jan 1;143:306-319. doi: 10.1016/j.ejmech.2017.11.075. Epub 2017 Nov 27.

PMID:
29197735
2.

2,6-Di(arylamino)-3-fluoropyridine Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors.

Sergeyev S, Yadav AK, Franck P, Michiels J, Lewi P, Heeres J, Vanham G, Ariën KK, Vande Velde CM, De Winter H, Maes BU.

J Med Chem. 2016 Mar 10;59(5):1854-68. doi: 10.1021/acs.jmedchem.5b01336. Epub 2016 Feb 8.

PMID:
26785139
3.

Prediction of neonatal respiratory function and pulmonary hypertension in fetuses with isolated congenital diaphragmatic hernia in the fetal endoscopic tracleal occlusion era: a single-center study.

Done E, Debeer A, Gucciardo L, Van Mieghem T, Lewi P, Devlieger R, De Catte L, Lewi L, Allegaert K, Deprest J.

Fetal Diagn Ther. 2015;37(1):24-32. doi: 10.1159/000364805. Epub 2014 Nov 8.

PMID:
25402437
4.

From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.

Venkatraj M, Ariën KK, Heeres J, Joossens J, Dirié B, Lyssens S, Michiels J, Cos P, Lewi PJ, Vanham G, Maes L, Van der Veken P, Augustyns K.

Bioorg Med Chem. 2014 Oct 1;22(19):5241-8. doi: 10.1016/j.bmc.2014.08.005. Epub 2014 Aug 14.

PMID:
25199582
5.

Analysis of the learning process for laparoscopic sacrocolpopexy: identification of challenging steps.

Claerhout F, Verguts J, Werbrouck E, Veldman J, Lewi P, Deprest J.

Int Urogynecol J. 2014 Sep;25(9):1185-91. doi: 10.1007/s00192-014-2412-z. Epub 2014 May 21.

PMID:
24846153
6.

Development and in vitro evaluation of a vaginal microbicide gel formulation for UAMC01398, a novel diaryltriazine NNRTI against HIV-1.

Grammen C, Ariën KK, Venkatraj M, Joossens J, Van der Veken P, Heeres J, Lewi PJ, Haenen S, Augustyns K, Vanham G, Augustijns P, Brouwers J.

Antiviral Res. 2014 Jan;101:113-21. doi: 10.1016/j.antiviral.2013.11.005. Epub 2013 Nov 20.

PMID:
24269474
7.

Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission.

Ariën KK, Venkatraj M, Michiels J, Joossens J, Vereecken K, Van der Veken P, Abdellati S, Cuylaerts V, Crucitti T, Heyndrickx L, Heeres J, Augustyns K, Lewi PJ, Vanham G.

J Antimicrob Chemother. 2013 Sep;68(9):2038-47. doi: 10.1093/jac/dkt166. Epub 2013 May 3.

PMID:
23645585
8.

Predictors of neonatal morbidity in fetuses with severe isolated congenital diaphragmatic hernia undergoing fetoscopic tracheal occlusion.

Doné E, Gratacos E, Nicolaides KH, Allegaert K, Valencia C, Castañon M, Martinez JM, Jani J, Van Mieghem T, Greenough A, Gomez O, Lewi P, Deprest J.

Ultrasound Obstet Gynecol. 2013 Jul;42(1):77-83. doi: 10.1002/uog.12445.

9.

Gestational age-specific reference ranges for amniotic fluid assessment in monochorionic diamniotic twin pregnancies.

Dekoninck P, Deprest J, Lewi P, Richter J, Galjaard S, Van Keirsbilck J, Van Calsteren K, Lewi L.

Ultrasound Obstet Gynecol. 2013 Jun;41(6):649-52. doi: 10.1002/uog.12387. Epub 2013 May 7.

10.

Sonographic evaluation of vascular pulmonary reactivity following oxygen administration in fetuses with normal lung development.

DeKoninck P, Lewi P, Done E, Richter J, Gucciardo L, Van Mieghem T, Deprest JA.

Prenat Diagn. 2012 Dec;32(13):1300-4. doi: 10.1002/pd.4000. Epub 2012 Nov 7.

PMID:
23132095
11.

Synthesis, evaluation and structure-activity relationships of triazine dimers as novel antiviral agents.

Venkatraj M, Ariën KK, Heeres J, Joossens J, Messagie J, Michiels J, Van der Veken P, Vanham G, Lewi PJ, Augustyns K.

Bioorg Med Chem Lett. 2012 Dec 1;22(23):7174-8. doi: 10.1016/j.bmcl.2012.09.066. Epub 2012 Sep 27.

PMID:
23084903
12.

Reverse transcriptase inhibitors as microbicides.

Lewi P, Heeres J, Ariën K, Venkatraj M, Joossens J, Van der Veken P, Augustyns K, Vanham G.

Curr HIV Res. 2012 Jan 1;10(1):27-35. Review.

PMID:
22264043
13.

Preterm prelabor rupture of membranes and fetal survival after minimally invasive fetal surgery: a systematic review of the literature.

Beck V, Lewi P, Gucciardo L, Devlieger R.

Fetal Diagn Ther. 2012;31(1):1-9. doi: 10.1159/000331165. Epub 2011 Nov 19. Review.

14.

Novel diarylpyridinones, diarylpyridazinones and diarylphthalazinones as potential HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs).

Venkatraj M, Ariën KK, Heeres J, Dirié B, Joossens J, Van Goethem S, Van der Veken P, Michiels J, Vande Velde CM, Vanham G, Lewi PJ, Augustyns K.

Bioorg Med Chem. 2011 Oct 15;19(20):5924-34. doi: 10.1016/j.bmc.2011.08.060. Epub 2011 Sep 1.

PMID:
21930388
15.

Results of fetal endoscopic tracheal occlusion for congenital diaphragmatic hernia and the set up of the randomized controlled TOTAL trial.

Dekoninck P, Gratacos E, Van Mieghem T, Richter J, Lewi P, Ancel AM, Allegaert K, Nicolaides K, Deprest J.

Early Hum Dev. 2011 Sep;87(9):619-24. doi: 10.1016/j.earlhumdev.2011.08.001.

PMID:
21907109
16.

Control of viral replication after cessation of HAART.

Van Gulck E, Heyndrickx L, Bracke L, Coppens S, Florence E, Buvé A, Lewi P, Vanham G.

AIDS Res Ther. 2011 Feb 11;8(1):6. doi: 10.1186/1742-6405-8-6.

17.

Technical aspects of fetal endoscopic tracheal occlusion for congenital diaphragmatic hernia.

Deprest J, Nicolaides K, Done' E, Lewi P, Barki G, Largen E, DeKoninck P, Sandaite I, Ville Y, Benachi A, Jani J, Amat-Roldan I, Gratacos E.

J Pediatr Surg. 2011 Jan;46(1):22-32. doi: 10.1016/j.jpedsurg.2010.10.008.

PMID:
21238635
18.

Cross-sectional study of tracheomegaly in children after fetal tracheal occlusion for severe congenital diaphragmatic hernia.

Breysem L, Debeer A, Claus F, Proesmans M, De Keyzer F, Lewi P, Allegaert K, Smet MH, Deprest J.

Radiology. 2010 Oct;257(1):226-32. doi: 10.1148/radiol.10092388. Epub 2010 Aug 16.

PMID:
20713614
19.

Conazoles.

Heeres J, Meerpoel L, Lewi P.

Molecules. 2010 Jun 9;15(6):4129-88. doi: 10.3390/molecules15064129. Review.

20.

Maternal hyperoxygenation test in fetuses undergoing FETO for severe isolated congenital diaphragmatic hernia.

Done E, Allegaert K, Lewi P, Jani J, Gucciardo L, Van Mieghem T, Gratacos E, Devlieger R, Van Schoubroeck D, Deprest J.

Ultrasound Obstet Gynecol. 2011 Mar;37(3):264-71. doi: 10.1002/uog.7753.

21.

Preterm rabbit lung tissue mechanics: maturational changes and effect of antenatal steroids.

Debeer A, Flemmer AW, Lewi PJ, Beheydt S, De Buck F, Zimmermann LJ, Naulaers G, Deprest JA.

Pediatr Pulmonol. 2010 Apr;45(4):349-55. doi: 10.1002/ppul.21191.

PMID:
20232469
22.

Accuracy of peritoneal fluid measurements by transvaginal ultrasonography.

Verguts J, Timmerman D, Bourne T, Lewi P, Koninckx P.

Ultrasound Obstet Gynecol. 2010 May;35(5):589-92. doi: 10.1002/uog.7632.

23.

Albumin as an adjunct to tracheal occlusion in fetal rats with congenital diaphragmatic hernia: a placebo-controlled study.

Klaritsch P, Mayer S, Sbragia L, Toelen J, Roubliova X, Lewi P, Deprest JA.

Am J Obstet Gynecol. 2010 Feb;202(2):198.e1-9. doi: 10.1016/j.ajog.2009.10.877. Epub 2009 Dec 24.

PMID:
20035915
24.

Sacrocolpopexy using xenogenic acellular collagen in patients at increased risk for graft-related complications.

Claerhout F, De Ridder D, Van Beckevoort D, Coremans G, Veldman J, Lewi P, Deprest J.

Neurourol Urodyn. 2010 Apr;29(4):563-7. doi: 10.1002/nau.20805.

PMID:
19731305
25.

Reference ranges for middle cerebral artery peak systolic velocity in monochorionic diamniotic twins: a longitudinal study.

Klaritsch P, Deprest J, Van Mieghem T, Gucciardo L, Doné E, Jani J, Lewi P, Rasmussen S, Lewi L.

Ultrasound Obstet Gynecol. 2009 Aug;34(2):149-54. doi: 10.1002/uog.6436.

26.

Implementation of laparoscopic sacrocolpopexy--a single centre's experience.

Claerhout F, Roovers JP, Lewi P, Verguts J, De Ridder D, Deprest J.

Int Urogynecol J Pelvic Floor Dysfunct. 2009 Sep;20(9):1119-25. doi: 10.1007/s00192-009-0914-x. Epub 2009 May 29.

PMID:
19479177
27.

The pregnancy and long-term neurodevelopmental outcome of monochorionic diamniotic twin gestations: a multicenter prospective cohort study from the first trimester onward.

Ortibus E, Lopriore E, Deprest J, Vandenbussche FP, Walther FJ, Diemert A, Hecher K, Lagae L, De Cock P, Lewi PJ, Lewi L.

Am J Obstet Gynecol. 2009 May;200(5):494.e1-8. doi: 10.1016/j.ajog.2009.01.048.

PMID:
19375567
28.

The effect of maternal betamethasone and fetal tracheal occlusion on pulmonary vascular morphometry in fetal rabbits with surgically induced diaphragmatic hernia: a placebo controlled morphologic study.

Roubliova XI, Lewi PJ, Verbeken EK, Vaast P, Jani JC, Lu H, Tibboel D, Deprest JA.

Prenat Diagn. 2009 Jul;29(7):674-81. doi: 10.1002/pd.2243.

PMID:
19365875
29.

Assessment of fetal cardiac function before and after therapy for twin-to-twin transfusion syndrome.

Van Mieghem T, Klaritsch P, Doné E, Gucciardo L, Lewi P, Verhaeghe J, Lewi L, Deprest J.

Am J Obstet Gynecol. 2009 Apr;200(4):400.e1-7. doi: 10.1016/j.ajog.2009.01.051.

PMID:
19318149
30.

Validation of the fetal myocardial performance index in the second and third trimesters of gestation.

Van Mieghem T, Gucciardo L, Lewi P, Lewi L, Van Schoubroeck D, Devlieger R, De Catte L, Verhaeghe J, Deprest J.

Ultrasound Obstet Gynecol. 2009 Jan;33(1):58-63. doi: 10.1002/uog.6238.

31.

Improving QSAR models for the biological activity of HIV Reverse Transcriptase inhibitors: Aspects of outlier detection and uninformative variable elimination.

Daszykowski M, Stanimirova I, Walczak B, Daeyaert F, de Jonge MR, Heeres J, Koymans LM, Lewi PJ, Vinkers HM, Janssen PA, Massart DL.

Talanta. 2005 Nov 15;68(1):54-60. doi: 10.1016/j.talanta.2005.04.071. Epub 2005 Jun 17.

PMID:
18970284
32.

Bleuler revisited: psychomotor slowing in schizophrenia as part of a catatonic symptom cluster.

Morrens M, Hulstijn W, Lewi P, Sabbe B.

Psychiatry Res. 2008 Oct 30;161(1):121-5. doi: 10.1016/j.psychres.2008.01.017. Epub 2008 Aug 22.

PMID:
18722670
33.

Effects of betamethasone on peripheral arterial development in term fetal rabbit.

Roubliova XI, Lewi PJ, Vaast P, Jani JC, Verbeken EK, Tibboel D, Deprest JA.

Pediatr Pulmonol. 2008 Aug;43(8):795-805. doi: 10.1002/ppul.20870.

PMID:
18615670
34.

Clinical outcome and placental characteristics of monochorionic diamniotic twin pairs with early- and late-onset discordant growth.

Lewi L, Gucciardo L, Huber A, Jani J, Van Mieghem T, Doné E, Cannie M, Gratacós E, Diemert A, Hecher K, Lewi P, Deprest J.

Am J Obstet Gynecol. 2008 Nov;199(5):511.e1-7. doi: 10.1016/j.ajog.2008.04.022. Epub 2008 Jun 9.

PMID:
18539257
35.

The role of ultrasound examination in the first trimester and at 16 weeks' gestation to predict fetal complications in monochorionic diamniotic twin pregnancies.

Lewi L, Lewi P, Diemert A, Jani J, Gucciardo L, Van Mieghem T, Doné E, Gratacós E, Huber A, Hecher K, Deprest J.

Am J Obstet Gynecol. 2008 Nov;199(5):493.e1-7. doi: 10.1016/j.ajog.2008.04.005. Epub 2008 Jun 9.

PMID:
18539256
36.

The outcome of monochorionic diamniotic twin gestations in the era of invasive fetal therapy: a prospective cohort study.

Lewi L, Jani J, Blickstein I, Huber A, Gucciardo L, Van Mieghem T, Doné E, Boes AS, Hecher K, Gratacós E, Lewi P, Deprest J.

Am J Obstet Gynecol. 2008 Nov;199(5):514.e1-8. doi: 10.1016/j.ajog.2008.03.050. Epub 2008 Jun 4.

PMID:
18533114
37.

Human immunodeficiency virus type 1 (HIV-1) integration: a potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection.

Terrazas-Aranda K, Van Herrewege Y, Hazuda D, Lewi P, Costi R, Di Santo R, Cara A, Vanham G.

Antimicrob Agents Chemother. 2008 Jul;52(7):2544-54. doi: 10.1128/AAC.01627-07. Epub 2008 May 12.

38.

The conductor and his orchestra.

Lewi PJ.

Drug Discov Today. 2008 Apr;13(7-8):281-4. doi: 10.1016/j.drudis.2008.02.008. No abstract available.

PMID:
18405839
39.

High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations.

Das K, Bauman JD, Clark AD Jr, Frenkel YV, Lewi PJ, Shatkin AJ, Hughes SH, Arnold E.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1466-71. doi: 10.1073/pnas.0711209105. Epub 2008 Jan 29.

40.

Antiviral compounds show enhanced activity in HIV-1 single cycle pseudovirus assays as compared to classical PBMC assays.

Heyndrickx L, Vermoesen T, Vereecken K, Kurth J, Coppens S, Aerts L, Ohagen A, Van Herrewege Y, Lewi P, Vanham G.

J Virol Methods. 2008 Mar;148(1-2):166-73. doi: 10.1016/j.jviromet.2007.11.009. Epub 2008 Jan 14.

PMID:
18192031
41.

Forty years of antipsychotic Drug research--from haloperidol to paliperidone--with Dr. Paul Janssen.

Awouters FH, Lewi PJ.

Arzneimittelforschung. 2007;57(10):625-32. Review.

PMID:
18074755
42.

Placental sharing, birthweight discordance, and vascular anastomoses in monochorionic diamniotic twin placentas.

Lewi L, Cannie M, Blickstein I, Jani J, Huber A, Hecher K, Dymarkowski S, Gratacós E, Lewi P, Deprest J.

Am J Obstet Gynecol. 2007 Dec;197(6):587.e1-8.

PMID:
18060944
43.

Effect of maternal administration of betamethasone on peripheral arterial development in fetal rabbit lungs.

Roubliova XI, Van der Biest AM, Vaast P, Lu H, Jani JC, Lewi PJ, Verbeken EK, Tibboel D, Deprest JA.

Neonatology. 2008;93(1):64-72. Epub 2007 Aug 16.

PMID:
17703103
44.

In vitro pre- and post-exposure prophylaxis using HIV inhibitors as microbicides against cell-free or cell-associated HIV-1 infection.

Terrazas-Aranda K, Van Herrewege Y, Lewi PJ, Van Roey J, Vanham G.

Antivir Chem Chemother. 2007;18(3):141-51.

PMID:
17626598
45.

Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains.

Mordant C, Schmitt B, Pasquier E, Demestre C, Queguiner L, Masungi C, Peeters A, Smeulders L, Bettens E, Hertogs K, Heeres J, Lewi P, Guillemont J.

Eur J Med Chem. 2007 May;42(5):567-79. Epub 2006 Dec 15.

PMID:
17223230
46.

A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides.

Van Herrewege Y, Michiels J, Waeytens A, De Boeck G, Salden E, Heyndrickx L, van den Mooter G, de Béthune MP, Andries K, Lewi P, Praet M, Vanham G.

Antiviral Res. 2007 May;74(2):111-24. Epub 2006 Nov 7.

PMID:
17097156
47.

Fetoscopic surgery: encouraged by clinical experience and boosted by instrument innovation.

Deprest J, Jani J, Lewi L, Ochsenbein-Kölble N, Cannie M, Doné E, Roubliova X, Van Mieghem T, Debeer A, Debuck F, Sbragia L, Toelen J, Devlieger R, Lewi P, Van de Velde M.

Semin Fetal Neonatal Med. 2006 Dec;11(6):398-412. Epub 2006 Oct 20. Review.

PMID:
17056307
48.

Stereotypy in schizophrenia.

Morrens M, Hulstijn W, Lewi PJ, De Hert M, Sabbe BG.

Schizophr Res. 2006 Jun;84(2-3):397-404. Epub 2006 Mar 20.

PMID:
16549339
49.
50.

Structure based activity prediction of HIV-1 reverse transcriptase inhibitors.

de Jonge MR, Koymans LM, Vinkers HM, Daeyaert FF, Heeres J, Lewi PJ, Janssen PA.

J Med Chem. 2005 Mar 24;48(6):2176-83.

PMID:
15771460

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