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Items: 14


Evaluating the quality of the 1000 genomes project data.

Belsare S, Levy-Sakin M, Mostovoy Y, Durinck S, Chaudhuri S, Xiao M, Peterson AS, Kwok PY, Seshagiri S, Wall JD.

BMC Genomics. 2019 Aug 16;20(1):620. doi: 10.1186/s12864-019-5957-x.


Genome maps across 26 human populations reveal population-specific patterns of structural variation.

Levy-Sakin M, Pastor S, Mostovoy Y, Li L, Leung AKY, McCaffrey J, Young E, Lam ET, Hastie AR, Wong KHY, Chung CYL, Ma W, Sibert J, Rajagopalan R, Jin N, Chow EYC, Chu C, Poon A, Lin C, Naguib A, Wang WP, Cao H, Chan TF, Yip KY, Xiao M, Kwok PY.

Nat Commun. 2019 Mar 4;10(1):1025. doi: 10.1038/s41467-019-08992-7.


De novo human genome assemblies reveal spectrum of alternative haplotypes in diverse populations.

Wong KHY, Levy-Sakin M, Kwok PY.

Nat Commun. 2018 Aug 2;9(1):3040. doi: 10.1038/s41467-018-05513-w.


A hybrid approach for de novo human genome sequence assembly and phasing.

Mostovoy Y, Levy-Sakin M, Lam J, Lam ET, Hastie AR, Marks P, Lee J, Chu C, Lin C, Džakula Ž, Cao H, Schlebusch SA, Giorda K, Schnall-Levin M, Wall JD, Kwok PY.

Nat Methods. 2016 Jul;13(7):587-90. doi: 10.1038/nmeth.3865. Epub 2016 May 9.


One-Pot Chemoenzymatic Cascade for Labeling of the Epigenetic Marker 5-Hydroxymethylcytosine.

Nifker G, Levy-Sakin M, Berkov-Zrihen Y, Shahal T, Gabrieli T, Fridman M, Ebenstein Y.

Chembiochem. 2015 Sep 7;16(13):1857-1860. doi: 10.1002/cbic.201500329. Epub 2015 Jul 27.


Light-emitting self-assembled peptide nucleic acids exhibit both stacking interactions and Watson-Crick base pairing.

Berger O, Adler-Abramovich L, Levy-Sakin M, Grunwald A, Liebes-Peer Y, Bachar M, Buzhansky L, Mossou E, Forsyth VT, Schwartz T, Ebenstein Y, Frolow F, Shimon LJ, Patolsky F, Gazit E.

Nat Nanotechnol. 2015 Apr;10(4):353-60. doi: 10.1038/nnano.2015.27. Epub 2015 Mar 16.


The influence of chemical chaperones on enzymatic activity under thermal and chemical stresses: common features and variation among diverse chemical families.

Levy-Sakin M, Berger O, Feibish N, Sharon N, Schnaider L, Shmul G, Amir Y, Buzhansky L, Gazit E.

PLoS One. 2014 Feb 10;9(2):e88541. doi: 10.1371/journal.pone.0088541. eCollection 2014.


Toward single-molecule optical mapping of the epigenome.

Levy-Sakin M, Grunwald A, Kim S, Gassman NR, Gottfried A, Antelman J, Kim Y, Ho SO, Samuel R, Michalet X, Lin RR, Dertinger T, Kim AS, Chung S, Colyer RA, Weinhold E, Weiss S, Ebenstein Y.

ACS Nano. 2014 Jan 28;8(1):14-26. doi: 10.1021/nn4050694. Epub 2013 Dec 20.


A blood-brain barrier (BBB) disrupter is also a potent α-synuclein (α-syn) aggregation inhibitor: a novel dual mechanism of mannitol for the treatment of Parkinson disease (PD).

Shaltiel-Karyo R, Frenkel-Pinter M, Rockenstein E, Patrick C, Levy-Sakin M, Schiller A, Egoz-Matia N, Masliah E, Segal D, Gazit E.

J Biol Chem. 2013 Jun 14;288(24):17579-88. doi: 10.1074/jbc.M112.434787. Epub 2013 May 1.


The effect of chemical chaperones on the assembly and stability of HIV-1 capsid protein.

Lampel A, Bram Y, Levy-Sakin M, Bacharach E, Gazit E.

PLoS One. 2013;8(4):e60867. doi: 10.1371/journal.pone.0060867. Epub 2013 Apr 5.


Beyond sequencing: optical mapping of DNA in the age of nanotechnology and nanoscopy.

Levy-Sakin M, Ebenstein Y.

Curr Opin Biotechnol. 2013 Aug;24(4):690-8. doi: 10.1016/j.copbio.2013.01.009. Epub 2013 Feb 18. Review.


Quantitative structure-activity relationship analysis of β-amyloid aggregation inhibitors.

Stempler S, Levy-Sakin M, Frydman-Marom A, Amir Y, Scherzer-Attali R, Buzhansky L, Gazit E, Senderowitz H.

J Comput Aided Mol Des. 2011 Feb;25(2):135-44. doi: 10.1007/s10822-010-9405-x. Epub 2010 Dec 17.


Targeting insulin amyloid assembly by small aromatic molecules: toward rational design of aggregation inhibitors.

Levy-Sakin M, Shreberk M, Daniel Y, Gazit E.

Islets. 2009 Nov-Dec;1(3):210-5. doi: 10.4161/isl.1.3.9609.


Complete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitor.

Scherzer-Attali R, Pellarin R, Convertino M, Frydman-Marom A, Egoz-Matia N, Peled S, Levy-Sakin M, Shalev DE, Caflisch A, Gazit E, Segal D.

PLoS One. 2010 Jun 14;5(6):e11101. doi: 10.1371/journal.pone.0011101.

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