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Items: 48


Multiple infection of cells changes the dynamics of basic viral evolutionary processes.

Wodarz D, Levy DN, Komarova NL.

Evol Lett. 2018 Dec 31;3(1):104-115. doi: 10.1002/evl3.95. eCollection 2019 Feb.


Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody.

He S, Fu Y, Guo J, Spear M, Yang J, Trinité B, Qin C, Fu S, Jiang Y, Zhang Z, Xu J, Ding H, Levy DN, Chen W, Petricoin E 3rd, Liotta LA, Shang H, Wu Y.

Sci Adv. 2019 Jan 9;5(1):eaat7911. doi: 10.1126/sciadv.aat7911. eCollection 2019 Jan.


Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques.

Wodarz D, Skinner PJ, Levy DN, Connick E.

PLoS Comput Biol. 2018 Oct 18;14(10):e1006461. doi: 10.1371/journal.pcbi.1006461. eCollection 2018 Oct.


Potent Inhibition of HIV-1 Replication in Resting CD4 T Cells by Resveratrol and Pterostilbene.

Chan CN, Trinité B, Levy DN.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00408-17. doi: 10.1128/AAC.00408-17. Print 2017 Sep.


Pyroptosis, superinfection, and the maintenance of the latent reservoir in HIV-1 infection.

Wodarz D, Levy DN.

Sci Rep. 2017 Jun 19;7(1):3834. doi: 10.1038/s41598-017-04130-9.


Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1.

Miller SM, Miles B, Guo K, Folkvord J, Meditz AL, McCarter MD, Levy DN, MaWhinney S, Santiago ML, Connick E.

J Virol. 2017 Aug 10;91(17). pii: e00430-17. doi: 10.1128/JVI.00430-17. Print 2017 Sep 1.


Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection.

Miles B, Miller SM, Folkvord JM, Levy DN, Rakasz EG, Skinner PJ, Connick E.

PLoS Pathog. 2016 Oct 7;12(10):e1005924. doi: 10.1371/journal.ppat.1005924. eCollection 2016 Oct.


Erratum for Trinité et al., HIV-1 Vpr- and Reverse Transcription-Induced Apoptosis in Resting Peripheral Blood CD4 T Cells and Protection by Common Gamma-Chain Cytokines.

Trinité B, Chan CN, Lee CS, Levy DN.

J Virol. 2016 Jul 27;90(16):7593. doi: 10.1128/JVI.01100-16. Print 2016 Aug 15. No abstract available.


Germinal Center T Follicular Helper Cells Are Highly Permissive to HIV-1 and Alter Their Phenotype during Virus Replication.

Kohler SL, Pham MN, Folkvord JM, Arends T, Miller SM, Miles B, Meditz AL, McCarter M, Levy DN, Connick E.

J Immunol. 2016 Mar 15;196(6):2711-22. doi: 10.4049/jimmunol.1502174. Epub 2016 Feb 12.


HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells.

Chan CN, Trinité B, Lee CS, Mahajan S, Anand A, Wodarz D, Sabbaj S, Bansal A, Goepfert PA, Levy DN.

Retrovirology. 2016 Jan 5;13:1. doi: 10.1186/s12977-015-0234-9.


A Subset of CD4/CD8 Double-Negative T Cells Expresses HIV Proteins in Patients on Antiretroviral Therapy.

DeMaster LK, Liu X, VanBelzen DJ, Trinité B, Zheng L, Agosto LM, Migueles SA, Connors M, Sambucetti L, Levy DN, Pasternak AO, O'Doherty U.

J Virol. 2015 Nov 4;90(5):2165-79. doi: 10.1128/JVI.01913-15.


HIV-1 Vpr- and Reverse Transcription-Induced Apoptosis in Resting Peripheral Blood CD4 T Cells and Protection by Common Gamma-Chain Cytokines.

Trinité B, Chan CN, Lee CS, Levy DN.

J Virol. 2015 Nov 4;90(2):904-16. doi: 10.1128/JVI.01770-15. Print 2016 Jan 15. Erratum in: J Virol. 2016 Jul 27;90(16):7593.


Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection.

Miles B, Miller SM, Folkvord JM, Kimball A, Chamanian M, Meditz AL, Arends T, McCarter MD, Levy DN, Rakasz EG, Skinner PJ, Connick E.

Nat Commun. 2015 Oct 20;6:8608. doi: 10.1038/ncomms9608.


Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells.

Galloway NL, Doitsh G, Monroe KM, Yang Z, Muñoz-Arias I, Levy DN, Greene WC.

Cell Rep. 2015 Sep 8;12(10):1555-1563. doi: 10.1016/j.celrep.2015.08.011. Epub 2015 Aug 28.


Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration.

Thierry S, Munir S, Thierry E, Subra F, Leh H, Zamborlini A, Saenz D, Levy DN, Lesbats P, Saïb A, Parissi V, Poeschla E, Deprez E, Delelis O.

Retrovirology. 2015 Mar 12;12:24. doi: 10.1186/s12977-015-0153-9.


Contribution of HIV-1 genomes that do not integrate to the basic reproductive ratio of the virus.

Lau JW, Levy DN, Wodarz D.

J Theor Biol. 2015 Feb 21;367:222-229. doi: 10.1016/j.jtbi.2014.12.004. Epub 2014 Dec 12.


Distinct patterns of Bcl-2 expression occur in R5- and X4-tropic HIV-1-producing lymphoid tissue cells infected ex vivo.

Haas MK, Levy DN, Folkvord JM, Connick E.

AIDS Res Hum Retroviruses. 2015 Mar;31(3):298-304. doi: 10.1089/aid.2014.0155. Epub 2014 Oct 29.


Suppression of Foxo1 activity and down-modulation of CD62L (L-selectin) in HIV-1 infected resting CD4 T cells.

Trinité B, Chan CN, Lee CS, Mahajan S, Luo Y, Muesing MA, Folkvord JM, Pham M, Connick E, Levy DN.

PLoS One. 2014 Oct 16;9(10):e110719. doi: 10.1371/journal.pone.0110719. eCollection 2014.


Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HIV-1 replication in human alveolar macrophages.

Weiden MD, Hoshino S, Levy DN, Li Y, Kumar R, Burke SA, Dawson R, Hioe CE, Borkowsky W, Rom WN, Hoshino Y.

PLoS One. 2014 Oct 1;9(10):e108476. doi: 10.1371/journal.pone.0108476. eCollection 2014.


On the laws of virus spread through cell populations.

Wodarz D, Chan CN, Trinité B, Komarova NL, Levy DN.

J Virol. 2014 Nov;88(22):13240-8. doi: 10.1128/JVI.02096-14. Epub 2014 Sep 3. Erratum in: J Virol. 2015 Jan 15;89(2):1484.


An HIV-1 replication pathway utilizing reverse transcription products that fail to integrate.

Trinité B, Ohlson EC, Voznesensky I, Rana SP, Chan CN, Mahajan S, Alster J, Burke SA, Wodarz D, Levy DN.

J Virol. 2013 Dec;87(23):12701-20. doi: 10.1128/JVI.01939-13. Epub 2013 Sep 18.


Synaptic transmission and the susceptibility of HIV infection to anti-viral drugs.

Komarova NL, Levy DN, Wodarz D.

Sci Rep. 2013;3:2103. doi: 10.1038/srep02103.


Relative contribution of free-virus and synaptic transmission to the spread of HIV-1 through target cell populations.

Komarova NL, Anghelina D, Voznesensky I, Trinité B, Levy DN, Wodarz D.

Biol Lett. 2012 Dec 26;9(1):20121049. doi: 10.1098/rsbl.2012.1049. Print 2013 Feb 23.


Effect of synaptic transmission on viral fitness in HIV infection.

Komarova NL, Levy DN, Wodarz D.

PLoS One. 2012;7(11):e48361. doi: 10.1371/journal.pone.0048361. Epub 2012 Nov 15.


Increased burst size in multiply infected cells can alter basic virus dynamics.

Cummings KW, Levy DN, Wodarz D.

Biol Direct. 2012 May 8;7:16. doi: 10.1186/1745-6150-7-16.


HLA-DR+ CD38+ CD4+ T lymphocytes have elevated CCR5 expression and produce the majority of R5-tropic HIV-1 RNA in vivo.

Meditz AL, Haas MK, Folkvord JM, Melander K, Young R, McCarter M, Mawhinney S, Campbell TB, Lie Y, Coakley E, Levy DN, Connick E.

J Virol. 2011 Oct;85(19):10189-200. doi: 10.1128/JVI.02529-10. Epub 2011 Aug 3.


Effect of multiple infection of cells on the evolutionary dynamics of HIV in vivo: implications for host adaptation mechanisms.

Wodarz D, Levy DN.

Exp Biol Med (Maywood). 2011 Aug;236(8):926-37. doi: 10.1258/ebm.2011.011062. Epub 2011 Jul 18. Review.


Multiploid inheritance of HIV-1 during cell-to-cell infection.

Del Portillo A, Tripodi J, Najfeld V, Wodarz D, Levy DN, Chen BK.

J Virol. 2011 Jul;85(14):7169-76. doi: 10.1128/JVI.00231-11. Epub 2011 May 4.


Effect of different modes of viral spread on the dynamics of multiply infected cells in human immunodeficiency virus infection.

Wodarz D, Levy DN.

J R Soc Interface. 2011 Feb 6;8(55):289-300. doi: 10.1098/rsif.2010.0266. Epub 2010 Jul 21.


CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription.

Bansal A, Carlson J, Yan J, Akinsiku OT, Schaefer M, Sabbaj S, Bet A, Levy DN, Heath S, Tang J, Kaslow RA, Walker BD, Ndung'u T, Goulder PJ, Heckerman D, Hunter E, Goepfert PA.

J Exp Med. 2010 Jan 18;207(1):51-9. doi: 10.1084/jem.20092060. Epub 2010 Jan 11.


The use of immune complex vaccines to enhance antibody responses against neutralizing epitopes on HIV-1 envelope gp120.

Hioe CE, Visciano ML, Kumar R, Liu J, Mack EA, Simon RE, Levy DN, Tuen M.

Vaccine. 2009 Dec 11;28(2):352-60. doi: 10.1016/j.vaccine.2009.10.040. Epub 2009 Oct 29.


Multiple HIV-1 infection of cells and the evolutionary dynamics of cytotoxic T lymphocyte escape mutants.

Wodarz D, Levy DN.

Evolution. 2009 Sep;63(9):2326-39. doi: 10.1111/j.1558-5646.2009.00727.x. Epub 2009 May 21.


Viral complementation allows HIV-1 replication without integration.

Gelderblom HC, Vatakis DN, Burke SA, Lawrie SD, Bristol GC, Levy DN.

Retrovirology. 2008 Jul 9;5:60. doi: 10.1186/1742-4690-5-60.


Human immunodeficiency virus evolution towards reduced replicative fitness in vivo and the development of AIDS.

Wodarz D, Levy DN.

Proc Biol Sci. 2007 Oct 7;274(1624):2481-90. Erratum in: Proc Biol Sci. 2008 Dec 22;275(1653):2897.


Antigenic conservation and immunogenicity of the HIV coreceptor binding site.

Decker JM, Bibollet-Ruche F, Wei X, Wang S, Levy DN, Wang W, Delaporte E, Peeters M, Derdeyn CA, Allen S, Hunter E, Saag MS, Hoxie JA, Hahn BH, Kwong PD, Robinson JE, Shaw GM.

J Exp Med. 2005 May 2;201(9):1407-19.


Bis-anthracycline antibiotics inhibit human immunodeficiency virus type 1 transcription.

Kutsch O, Levy DN, Bates PJ, Decker J, Kosloff BR, Shaw GM, Priebe W, Benveniste EN.

Antimicrob Agents Chemother. 2004 May;48(5):1652-63.


Dynamics of HIV-1 recombination in its natural target cells.

Levy DN, Aldrovandi GM, Kutsch O, Shaw GM.

Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4204-9. Epub 2004 Mar 9. Erratum in: Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1808.


Unselected mutations in the human immunodeficiency virus type 1 genome are mostly nonsynonymous and often deleterious.

Gao F, Chen Y, Levy DN, Conway JA, Kepler TB, Hui H.

J Virol. 2004 Mar;78(5):2426-33.


CD154-CD40-induced reactivation of latent HIV-1 infection.

Kutsch O, Levy DN, Kosloff BR, Shaw GM, Benveniste EN.

Virology. 2003 Sep 15;314(1):261-70.


The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product.

Refaeli Y, Levy DN, Weiner DB.

Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3621-5.


The vpr regulatory gene of HIV.

Levy DN, Refaeli Y, Weiner DB.

Curr Top Microbiol Immunol. 1995;193:209-36. Review. No abstract available.


Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1.

Levy DN, Refaeli Y, MacGregor RR, Weiner DB.

Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):10873-7.


Induction of cell differentiation by human immunodeficiency virus 1 vpr.

Levy DN, Fernandes LS, Williams WV, Weiner DB.

Cell. 1993 Feb 26;72(4):541-50.


Identification of murine complement receptor type 2.

Fingeroth JD, Benedict MA, Levy DN, Strominger JL.

Proc Natl Acad Sci U S A. 1989 Jan;86(1):242-6.


Normal cellular counterparts of B cell chronic lymphocytic leukemia.

Freedman AS, Boyd AW, Bieber FR, Daley J, Rosen K, Horowitz JC, Levy DN, Nadler LM.

Blood. 1987 Aug;70(2):418-27.


Expression of B cell activation antigens on normal and malignant B cells.

Freedman AS, Boyd AW, Berrebi A, Horowitz JC, Levy DN, Rosen KJ, Daley J, Slaughenhoupt B, Levine H, Nadler LM.

Leukemia. 1987 Jan;1(1):9-15.


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