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Items: 38

1.

Demonstrating laboratory proficiency in bacterial mutagenicity assays for regulatory submission.

Levy DD, Hakura A, Elespuru RK, Escobar PA, Kato M, Lott J, Moore MM, Sugiyama KI.

Mutat Res. 2019 Dec;848:403075. doi: 10.1016/j.mrgentox.2019.07.005. Epub 2019 Jul 12.

2.

Recommended criteria for the evaluation of bacterial mutagenicity data (Ames test).

Levy DD, Zeiger E, Escobar PA, Hakura A, van der Leede BM, Kato M, Moore MM, Sugiyama KI.

Mutat Res. 2019 Dec;848:403074. doi: 10.1016/j.mrgentox.2019.07.004. Epub 2019 Aug 5.

3.

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.

Kirkland D, Levy DD, LeBaron MJ, Aardema MJ, Beevers C, Bhalli J, Douglas GR, Escobar PA, Farabaugh CS, Guerard M, Johnson GE, Kulkarni R, Le Curieux F, Long AS, Lott J, Lovell DP, Luijten M, Marchetti F, Nicolette JJ, Pfuhler S, Roberts DJ, Stankowski LF Jr, Thybaud V, Weiner SK, Williams A, Witt KL, Young R.

Mutat Res Genet Toxicol Environ Mutagen. 2019 Mar;839:21-35. doi: 10.1016/j.mrgentox.2019.01.007. Epub 2019 Jan 18.

4.

Main issues addressed in the 2014-2015 revisions to the OECD Genetic Toxicology Test Guidelines.

Thybaud V, Lorge E, Levy DD, van Benthem J, Douglas GR, Marchetti F, Moore MM, Schoeny R.

Environ Mol Mutagen. 2017 Jun;58(5):284-295. doi: 10.1002/em.22079. Epub 2017 Mar 7.

PMID:
28266061
5.

IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk.

MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Johnson GE, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V.

Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:66-78. doi: 10.1016/j.mrgentox.2014.10.008. Epub 2014 Oct 27.

6.

IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure-response relationships and points of departure (PoDs).

MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V, Johnson GE.

Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:55-65. doi: 10.1016/j.mrgentox.2014.09.011. Epub 2014 Oct 13.

7.

Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT).

Speit G, Kojima H, Burlinson B, Collins AR, Kasper P, Plappert-Helbig U, Uno Y, Vasquez M, Beevers C, De Boeck M, Escobar PA, Kitamoto S, Pant K, Pfuhler S, Tanaka J, Levy DD.

Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:6-12. doi: 10.1016/j.mrgentox.2014.09.006. Epub 2014 Sep 22.

PMID:
25953395
8.

In vivo genotoxicity of estragole in male F344 rats.

Ding W, Levy DD, Bishop ME, Pearce MG, Davis KJ, Jeffrey AM, Duan JD, Williams GM, White GA, Lyn-Cook LE, Manjanatha MG.

Environ Mol Mutagen. 2015 May;56(4):356-65. doi: 10.1002/em.21918. Epub 2014 Oct 31.

PMID:
25361439
9.

Evaluation of the highest concentrations used in the in vitro chromosome aberrations assay.

Brookmire L, Chen JJ, Levy DD.

Environ Mol Mutagen. 2013 Jan;54(1):36-43. doi: 10.1002/em.21738. Epub 2012 Oct 17.

PMID:
23076808
10.

Methyleugenol genotoxicity in the Fischer 344 rat using the comet assay and pathway-focused gene expression profiling.

Ding W, Levy DD, Bishop ME, Lyn-Cook Lascelles E, Kulkarni R, Chang CW, Aidoo A, Manjanatha MG.

Toxicol Sci. 2011 Sep;123(1):103-12. doi: 10.1093/toxsci/kfr153. Epub 2011 Jun 9.

PMID:
21659616
11.

The science and regulations of probiotic food and supplement product labeling.

Sanders ME, Levy DD.

Ann N Y Acad Sci. 2011 Feb;1219 Suppl 1:E1-E23. doi: 10.1111/j.1749-6632.2010.05956.x.

PMID:
21332758
12.

Safety assessment of probiotics for human use.

Sanders ME, Akkermans LM, Haller D, Hammerman C, Heimbach J, Hörmannsperger G, Huys G, Levy DD, Lutgendorff F, Mack D, Phothirath P, Solano-Aguilar G, Vaughan E.

Gut Microbes. 2010 May-Jun;1(3):164-85. doi: 10.4161/gmic.1.3.12127. Epub 2010 Mar 4. Review.

13.

Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenetics assays (chromosome aberrations and micronucleus).

Galloway S, Lorge E, Aardema MJ, Eastmond D, Fellows M, Heflich R, Kirkland D, Levy DD, Lynch AM, Marzin D, Morita T, Schuler M, Speit G.

Mutat Res. 2011 Aug 16;723(2):77-83. doi: 10.1016/j.mrgentox.2011.01.003. Epub 2011 Jan 19.

PMID:
21255675
14.

Follow-up actions from positive results of in vitro genetic toxicity testing.

Dearfield KL, Thybaud V, Cimino MC, Custer L, Czich A, Harvey JS, Hester S, Kim JH, Kirkland D, Levy DD, Lorge E, Moore MM, Ouédraogo-Arras G, Schuler M, Suter W, Sweder K, Tarlo K, van Benthem J, van Goethem F, Witt KL.

Environ Mol Mutagen. 2011 Apr;52(3):177-204. doi: 10.1002/em.20617. Epub 2010 Oct 20. Review.

15.

Current and future application of genetic toxicity assays: the role and value of in vitro mammalian assays.

Elespuru RK, Agarwal R, Atrakchi AH, Bigger CA, Heflich RH, Jagannath DR, Levy DD, Moore MM, Ouyang Y, Robison TW, Sotomayor RE, Cimino MC, Dearfield KL.

Toxicol Sci. 2009 Jun;109(2):172-9. doi: 10.1093/toxsci/kfp067. Epub 2009 Mar 31.

PMID:
19336498
16.

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability.

Radisky DC, Levy DD, Littlepage LE, Liu H, Nelson CM, Fata JE, Leake D, Godden EL, Albertson DG, Nieto MA, Werb Z, Bissell MJ.

Nature. 2005 Jul 7;436(7047):123-7.

17.
18.

Evolution of multi-gene segments in the mutS-rpoS intergenic region of Salmonella enterica serovar Typhimurium LT2.

Kotewicz ML, Li B, Levy DD, LeClerc JE, Shifflet AW, Cebula TA.

Microbiology. 2002 Aug;148(Pt 8):2531-2540. doi: 10.1099/00221287-148-8-2531.

PMID:
12177346
19.

Analysis of flour and food samples for cry9C from bioengineered corn.

Orlandi PA, Lampel KA, South PK, Assar SK, Carter L, Levy DD.

J Food Prot. 2002 Feb;65(2):426-31.

PMID:
11848580
20.

Microarray analysis of microbial virulence factors.

Chizhikov V, Rasooly A, Chumakov K, Levy DD.

Appl Environ Microbiol. 2001 Jul;67(7):3258-63.

21.

Fidelity of replication of repetitive DNA in mutS and repair proficient Escherichia coli.

Levy DD, Cebula TA.

Mutat Res. 2001 Mar 1;474(1-2):1-14.

PMID:
11239958
22.

Mutagenesis patterns in a tRNA mutation marker gene altered to include repetitive sequence replicated in mutS E. coli.

Levy DD, Cebula TA.

Ann N Y Acad Sci. 1999 May 18;870:392-5. No abstract available.

PMID:
10415506
23.

Sequence-dependent mutations in a shuttle vector plasmid replicated in a mismatch repair deficient human cell line.

Tobi SE, Levy DD, Seidman1 MM, Kraemer1 KH.

Carcinogenesis. 1999 Jul;20(7):1293-301.

PMID:
10383903
24.

Triplex formation by oligonucleotides containing 5-(1-propynyl)-2'-deoxyuridine: decreased magnesium dependence and improved intracellular gene targeting.

Lacroix L, Lacoste J, Reddoch JF, Mergny JL, Levy DD, Seidman MM, Matteucci MD, Glazer PM.

Biochemistry. 1999 Feb 9;38(6):1893-901.

PMID:
10026270
25.

Plasmodium chabaudi: cDNA of Pc96, a protective antigen associated with the erythrocyte membrane of infected erythrocytes.

Wanidworanun C, Levy DD, Shear HL.

Exp Parasitol. 1997 Jan;85(1):92-8. No abstract available.

PMID:
9024207
26.

Single nucleotide positions have proximal and distal influence on UV mutation hotspots and coldspots.

Levy DD, Magee AD, Seidman MM.

J Mol Biol. 1996 May 3;258(2):251-60.

PMID:
8627623
27.

The influence of single base changes on UV mutational activity at two translocated hotspots.

Levy DD, Magee AD, Namiki C, Seidman MM.

J Mol Biol. 1996 Jan 26;255(3):435-45.

PMID:
8568888
28.
29.

Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.

Wang G, Levy DD, Seidman MM, Glazer PM.

Mol Cell Biol. 1995 Mar;15(3):1759-68.

30.

Xeroderma pigmentosum and related disorders: examining the linkage between defective DNA repair and cancer.

Kraemer KH, Levy DD, Parris CN, Gozukara EM, Moriwaki S, Adelberg S, Seidman MM.

J Invest Dermatol. 1994 Nov;103(5 Suppl):96S-101S. Review.

31.
32.
34.

Toxicity of 3-aminobenzamide to Chinese hamster cells containing 5-hydroxymethyluracil in their DNA.

Boorstein RJ, Levy DD, Teebor GW.

Cancer Res. 1987 Aug 15;47(16):4372-7.

35.

5-Hydroxymethyluracil-DNA glycosylase activity may be a differentiated mammalian function.

Boorstein RJ, Levy DD, Teebor GW.

Mutat Res. 1987 May;183(3):257-63.

PMID:
3553917
36.

Serologic procedures performed in hydrophilized polystyrene cuvettes and borate glass tubes: a comparative study.

Wenz B, Gurtlinger K, Levy DD, Dugan EP.

Transfusion. 1982 Jul-Aug;22(4):326-8.

PMID:
6179269
37.

A pulsed electrical stimulation technique for inducing bone growth.

Levy DD.

Ann N Y Acad Sci. 1974;238:478-90. No abstract available.

PMID:
4531277
38.

Inducing bone growth in vivo by pulse stimulation.

Levy DD, Rubin B.

Clin Orthop Relat Res. 1972;88:218-22. No abstract available.

PMID:
5086569

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