Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 169


Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens.

Hester MM, Lee CK, Abraham A, Khoshkenar P, Ostroff GR, Levitz SM, Specht CA.

Vaccine. 2020 Jan 16;38(3):620-626. doi: 10.1016/j.vaccine.2019.10.051. Epub 2019 Nov 4.


Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen Cryptococcus gattii.

Lam WC, Upadhya R, Specht CA, Ragsdale AE, Hole CR, Levitz SM, Lodge JK.

mSphere. 2019 Oct 9;4(5). pii: e00644-19. doi: 10.1128/mSphere.00644-19.


CD82 controls CpG-dependent TLR9 signaling.

Khan NS, Lukason DP, Feliu M, Ward RA, Lord AK, Reedy JL, Ramirez-Ortiz ZG, Tam JM, Kasperkovitz PV, Negoro PE, Vyas TD, Xu S, Brinkmann MM, Acharaya M, Artavanis-Tsakonas K, Frickel EM, Becker CE, Dagher Z, Kim YM, Latz E, Ploegh HL, Mansour MK, Miranti CK, Levitz SM, Vyas JM.

FASEB J. 2019 Nov;33(11):12500-12514. doi: 10.1096/fj.201901547R. Epub 2019 Aug 13.


A novel vaccine platform using glucan particles for induction of protective responses against Francisella tularensis and other pathogens.

Abraham A, Ostroff G, Levitz SM, Oyston PCF.

Clin Exp Immunol. 2019 Nov;198(2):143-152. doi: 10.1111/cei.13356. Epub 2019 Sep 12. Review.


Fungal immunology in clinical practice: Magical realism or practical reality?

Chang CC, Levitz SM.

Med Mycol. 2019 Jun 1;57(Supplement_3):S294-S306. doi: 10.1093/mmy/myy165.


Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome Is Associated With Dysregulation of IL-7/IL-7 Receptor Signaling Pathway in T Cells and Monocyte Activation.

Akilimali NA, Muema DM, Specht C, Chang CC, Moosa MS, Levitz SM, Lewin SR, French MA, Ndungʼu T.

J Acquir Immune Defic Syndr. 2019 Apr 15;80(5):596-604. doi: 10.1097/QAI.0000000000001946.


Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles.

Whelan AO, Flick-Smith HC, Homan J, Shen ZT, Carpenter Z, Khoshkenar P, Abraham A, Walker NJ, Levitz SM, Ostroff GR, Oyston PCF.

PLoS One. 2018 Oct 8;13(10):e0200213. doi: 10.1371/journal.pone.0200213. eCollection 2018.


Autocrine IL-10 Signaling Promotes Dendritic Cell Type-2 Activation and Persistence of Murine Cryptococcal Lung Infection.

Teitz-Tennenbaum S, Viglianti SP, Roussey JA, Levitz SM, Olszewski MA, Osterholzer JJ.

J Immunol. 2018 Oct 1;201(7):2004-2015. doi: 10.4049/jimmunol.1800070. Epub 2018 Aug 10.


Vaccination with an alkaline extract of Histoplasma capsulatum packaged in glucan particles confers protective immunity in mice.

Deepe GS Jr, Buesing WR, Ostroff GR, Abraham A, Specht CA, Huang H, Levitz SM.

Vaccine. 2018 May 31;36(23):3359-3367. doi: 10.1016/j.vaccine.2018.04.047. Epub 2018 May 2.


Reemergence of Intravenous Drug Use as Risk Factor for Candidemia, Massachusetts, USA.

Poowanawittayakom N, Dutta A, Stock S, Touray S, Ellison RT 3rd, Levitz SM.

Emerg Infect Dis. 2018 Apr;24(4). doi: 10.3201/eid2404.171807.


Host Control of Fungal Infections: Lessons from Basic Studies and Human Cohorts.

Lionakis MS, Levitz SM.

Annu Rev Immunol. 2018 Apr 26;36:157-191. doi: 10.1146/annurev-immunol-042617-053318. Epub 2017 Dec 13. Review.


Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species.

Specht CA, Lee CK, Huang H, Hester MM, Liu J, Luckie BA, Torres Santana MA, Mirza Z, Khoshkenar P, Abraham A, Shen ZT, Lodge JK, Akalin A, Homan J, Ostroff GR, Levitz SM.

mBio. 2017 Nov 28;8(6). pii: e01872-17. doi: 10.1128/mBio.01872-17.


Modulating host immune responses to fight invasive fungal infections.

Scriven JE, Tenforde MW, Levitz SM, Jarvis JN.

Curr Opin Microbiol. 2017 Dec;40:95-103. doi: 10.1016/j.mib.2017.10.018. Epub 2017 Nov 15. Review.


A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1β Release in Response to a Pathogenic Fungus.

Ketelut-Carneiro N, Ghosh S, Levitz SM, Fitzgerald KA, da Silva JS.

J Infect Dis. 2018 Jan 4;217(2):329-339. doi: 10.1093/infdis/jix568.


Immunotherapeutic approaches to treatment of fungal diseases.

Armstrong-James D, Brown GD, Netea MG, Zelante T, Gresnigt MS, van de Veerdonk FL, Levitz SM.

Lancet Infect Dis. 2017 Dec;17(12):e393-e402. doi: 10.1016/S1473-3099(17)30442-5. Epub 2017 Jul 31. Review.


Fungal Recognition and Host Defense Mechanisms.

Dambuza IM, Levitz SM, Netea MG, Brown GD.

Microbiol Spectr. 2017 Jul;5(4). doi: 10.1128/microbiolspec.FUNK-0050-2016. Review.


Beta-Glucan Particles as Vaccine Adjuvant Carriers.

Mirza Z, Soto ER, Dikengil F, Levitz SM, Ostroff GR.

Methods Mol Biol. 2017;1625:143-157. doi: 10.1007/978-1-4939-7104-6_11.


Properdin Levels in Individuals with Chemotherapy-Induced Neutropenia.

Tsyrkunou A, Agarwal S, Koirala B, Finberg RW, Nath R, Barton B, Levitz SM, Wang JP, Ram S.

Open Forum Infect Dis. 2016 Dec 7;4(1):ofw250. doi: 10.1093/ofid/ofw250. eCollection 2017 Winter.


The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis.

Kwon-Chung KJ, Bennett JE, Wickes BL, Meyer W, Cuomo CA, Wollenburg KR, Bicanic TA, Castañeda E, Chang YC, Chen J, Cogliati M, Dromer F, Ellis D, Filler SG, Fisher MC, Harrison TS, Holland SM, Kohno S, Kronstad JW, Lazera M, Levitz SM, Lionakis MS, May RC, Ngamskulrongroj P, Pappas PG, Perfect JR, Rickerts V, Sorrell TC, Walsh TJ, Williamson PR, Xu J, Zelazny AM, Casadevall A.

mSphere. 2017 Jan 11;2(1). pii: e00357-16. doi: 10.1128/mSphere.00357-16. eCollection 2017 Jan-Feb.


Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma.

Guerra ES, Lee CK, Specht CA, Yadav B, Huang H, Akalin A, Huh JR, Mueller C, Levitz SM.

PLoS Pathog. 2017 Jan 17;13(1):e1006175. doi: 10.1371/journal.ppat.1006175. eCollection 2017 Jan.


Aspergillus vaccines: Hardly worth studying or worthy of hard study?

Levitz SM.

Med Mycol. 2017 Jan 1;55(1):103-108. Epub 2016 Sep 17. Review.


XTT Assay of Antifungal Activity.

Loures FV, Levitz SM.

Bio Protoc. 2015 Aug 5;5(15). pii: e1543.


Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of Cryptococcus neoformans.

Upadhya R, Lam WC, Maybruck B, Specht CA, Levitz SM, Lodge JK.

mBio. 2016 May 10;7(3). pii: e00547-16. doi: 10.1128/mBio.00547-16.


Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts.

Specht CA, Lee CK, Huang H, Tipper DJ, Shen ZT, Lodge JK, Leszyk J, Ostroff GR, Levitz SM.

mBio. 2015 Dec 22;6(6):e01905-15. doi: 10.1128/mBio.01905-15.


Paradoxical Immune Responses in Non-HIV Cryptococcal Meningitis.

Panackal AA, Wuest SC, Lin YC, Wu T, Zhang N, Kosa P, Komori M, Blake A, Browne SK, Rosen LB, Hagen F, Meis J, Levitz SM, Quezado M, Hammoud D, Bennett JE, Bielekova B, Williamson PR.

PLoS Pathog. 2015 May 28;11(5):e1004884. doi: 10.1371/journal.ppat.1004884. eCollection 2015 May.


Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

Wiesner DL, Specht CA, Lee CK, Smith KD, Mukaremera L, Lee ST, Lee CG, Elias JA, Nielsen JN, Boulware DR, Bohjanen PR, Jenkins MK, Levitz SM, Nielsen K.

PLoS Pathog. 2015 Mar 12;11(3):e1004701. doi: 10.1371/journal.ppat.1004701. eCollection 2015 Mar.


Recognition of Aspergillus fumigatus hyphae by human plasmacytoid dendritic cells is mediated by dectin-2 and results in formation of extracellular traps.

Loures FV, Röhm M, Lee CK, Santos E, Wang JP, Specht CA, Calich VL, Urban CF, Levitz SM.

PLoS Pathog. 2015 Feb 6;11(2):e1004643. doi: 10.1371/journal.ppat.1004643. eCollection 2015 Feb.


Exploiting fungal cell wall components in vaccines.

Levitz SM, Huang H, Ostroff GR, Specht CA.

Semin Immunopathol. 2015 Mar;37(2):199-207. doi: 10.1007/s00281-014-0460-6. Epub 2014 Nov 18. Review.


Multifocal Rhizopus microsporus lung infection following brush clearing.

Tsyrkunou AV, Ellison RT 3rd, Akalin A, Wiederhold N, Sutton DA, Lindner J, Fan H, Levitz SM, Zivna I.

Med Mycol Case Rep. 2014 Aug 8;6:14-7. doi: 10.1016/j.mmcr.2014.08.001. eCollection 2014 Oct.


Fungal vaccines and immunotherapeutics.

Santos E, Levitz SM.

Cold Spring Harb Perspect Med. 2014 Nov 3;4(11):a019711. doi: 10.1101/cshperspect.a019711. Review.


Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans.

Ganesan S, Rathinam VAK, Bossaller L, Army K, Kaiser WJ, Mocarski ES, Dillon CP, Green DR, Mayadas TN, Levitz SM, Hise AG, Silverman N, Fitzgerald KA.

J Immunol. 2014 Sep 1;193(5):2519-2530. doi: 10.4049/jimmunol.1400276. Epub 2014 Jul 25.


Spectrum and mechanisms of inflammasome activation by chitosan.

Bueter CL, Lee CK, Wang JP, Ostroff GR, Specht CA, Levitz SM.

J Immunol. 2014 Jun 15;192(12):5943-51. doi: 10.4049/jimmunol.1301695. Epub 2014 May 14.


A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling β-glucan microparticles.

De Jesus M, Ostroff GR, Levitz SM, Bartling TR, Mantis NJ.

PLoS One. 2014 Mar 14;9(3):e91002. doi: 10.1371/journal.pone.0091002. eCollection 2014.


Novel strategies to enhance vaccine immunity against coccidioidomycosis.

Cole GT, Hung CY, Sanderson SD, Hurtgen BJ, Wüthrich M, Klein BS, Deepe GS, Ostroff GR, Levitz SM.

PLoS Pathog. 2013;9(12):e1003768. doi: 10.1371/journal.ppat.1003768. Epub 2013 Dec 19. No abstract available.


NKp30 enables NK cells to act naturally with fungi.

Quintin J, Levitz SM.

Cell Host Microbe. 2013 Oct 16;14(4):369-71. doi: 10.1016/j.chom.2013.10.001.


Characterization and optimization of the glucan particle-based vaccine platform.

Huang H, Ostroff GR, Lee CK, Specht CA, Levitz SM.

Clin Vaccine Immunol. 2013 Oct;20(10):1585-91. doi: 10.1128/CVI.00463-13. Epub 2013 Aug 14.


Cryptococcosis-IRIS is associated with lower cryptococcus-specific IFN-γ responses before antiretroviral therapy but not higher T-cell responses during therapy.

Chang CC, Lim A, Omarjee S, Levitz SM, Gosnell BI, Spelman T, Elliott JH, Carr WH, Moosa MY, Ndung'u T, Lewin SR, French MA.

J Infect Dis. 2013 Sep;208(6):898-906. doi: 10.1093/infdis/jit271. Epub 2013 Jun 12.


The phenotype of the Cryptococcus-specific CD4+ memory T-cell response is associated with disease severity and outcome in HIV-associated cryptococcal meningitis.

Jarvis JN, Casazza JP, Stone HH, Meintjes G, Lawn SD, Levitz SM, Harrison TS, Koup RA.

J Infect Dis. 2013 Jun 15;207(12):1817-28. doi: 10.1093/infdis/jit099. Epub 2013 Mar 14.


Innate sensing of chitin and chitosan.

Bueter CL, Specht CA, Levitz SM.

PLoS Pathog. 2013 Jan;9(1):e1003080. doi: 10.1371/journal.ppat.1003080. Epub 2013 Jan 10. No abstract available.


Hidden killers: human fungal infections.

Brown GD, Denning DW, Gow NA, Levitz SM, Netea MG, White TC.

Sci Transl Med. 2012 Dec 19;4(165):165rv13. doi: 10.1126/scitranslmed.3004404. Review.


Phomopsis bougainvilleicola prepatellar bursitis in a renal transplant recipient.

Cariello PF, Wickes BL, Sutton DA, Castlebury LA, Levitz SM, Finberg RW, Thompson EH, Daly JS.

J Clin Microbiol. 2013 Feb;51(2):692-5. doi: 10.1128/JCM.02674-12. Epub 2012 Nov 28.


Compounding drugs contaminated with fungi: a recipe for disaster.

Levitz SM.

Emerg Microbes Infect. 2012 Nov;1(11):e41. doi: 10.1038/emi.2012.46. No abstract available.


Construction and evaluation of a novel recombinant T cell epitope-based vaccine against Coccidioidomycosis.

Hurtgen BJ, Hung CY, Ostroff GR, Levitz SM, Cole GT.

Infect Immun. 2012 Nov;80(11):3960-74. doi: 10.1128/IAI.00566-12. Epub 2012 Sep 4.


Relative contributions of dectin-1 and complement to immune responses to particulate β-glucans.

Huang H, Ostroff GR, Lee CK, Agarwal S, Ram S, Rice PA, Specht CA, Levitz SM.

J Immunol. 2012 Jul 1;189(1):312-7. doi: 10.4049/jimmunol.1200603. Epub 2012 May 30.


Tackling human fungal infections.

Brown GD, Denning DW, Levitz SM.

Science. 2012 May 11;336(6082):647. doi: 10.1126/science.1222236. No abstract available.


Beyond empiricism: informing vaccine development through innate immunity research.

Levitz SM, Golenbock DT.

Cell. 2012 Mar 16;148(6):1284-92. doi: 10.1016/j.cell.2012.02.012. Review.


Innate recognition of cell wall β-glucans drives invariant natural killer T cell responses against fungi.

Cohen NR, Tatituri RV, Rivera A, Watts GF, Kim EY, Chiba A, Fuchs BB, Mylonakis E, Besra GS, Levitz SM, Brigl M, Brenner MB.

Cell Host Microbe. 2011 Nov 17;10(5):437-50. doi: 10.1016/j.chom.2011.09.011.


Contributions of the MyD88-dependent receptors IL-18R, IL-1R, and TLR9 to host defenses following pulmonary challenge with Cryptococcus neoformans.

Wang JP, Lee CK, Akalin A, Finberg RW, Levitz SM.

PLoS One. 2011;6(10):e26232. doi: 10.1371/journal.pone.0026232. Epub 2011 Oct 19.


A chronological history of the International Conference on Cryptococcus and Cryptococcosis (ICCC), an invaluable forum for growth of the cryptococcal research field and clinical practice.

Kwon-Chung KJ, Perfect JR, Levitz SM.

Mycopathologia. 2012 Jun;173(5-6):287-93. doi: 10.1007/s11046-011-9481-z. Epub 2011 Oct 29.


Dynamic virulence: real-time assessment of intracellular pathogenesis links Cryptococcus neoformans phenotype with clinical outcome.

Mansour MK, Vyas JM, Levitz SM.

mBio. 2011 Sep 27;2(5). pii: e00217-11. doi: 10.1128/mBio.00217-11. Print 2011.

Supplemental Content

Loading ...
Support Center