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Items: 1 to 50 of 347

1.

Responsibilities of Data Monitoring Committees: Consensus Recommendations.

Bierer BE, Li R, Seltzer J, Sleeper LA, Frank E, Knirsch C, Aldinger CE, Levine RJ, Massaro J, Shah A, Barnes M, Snapinn S, Wittes J.

Ther Innov Regul Sci. 2016 Sep;50(5):648-659. doi: 10.1177/2168479016646812. Epub 2016 Jul 10.

PMID:
30231760
2.

Eli Lilly and Company's bioethics framework for human biomedical research.

Van Campen LE, Therasse DG, Klopfenstein M, Levine RJ.

Curr Med Res Opin. 2015 Nov;31(11):2081-93. doi: 10.1185/03007995.2015.1087987. Epub 2015 Oct 13.

PMID:
26325585
3.

Development, implementation and critique of a bioethics framework for pharmaceutical sponsors of human biomedical research.

Van Campen LE, Therasse DG, Klopfenstein M, Levine RJ.

Curr Med Res Opin. 2015 Nov;31(11):2071-80. doi: 10.1185/03007995.2015.1087986. Epub 2015 Oct 15.

PMID:
26325424
4.

Criminalization of HIV transmission and exposure: research and policy agenda.

Lazzarini Z, Galletly CL, Mykhalovskiy E, Harsono D, O'Keefe E, Singer M, Levine RJ.

Am J Public Health. 2013 Aug;103(8):1350-3. doi: 10.2105/AJPH.2013.301267. Epub 2013 Jun 13.

5.

Adverse drug effects and angioedema hospitalizations in the United States from 2000 to 2009.

Lin RY, Levine RJ, Lin H.

Allergy Asthma Proc. 2013 Jan-Feb;34(1):65-71. doi: 10.2500/aap.2013.34.3618.

PMID:
23406938
6.

Knowledge and usability of a trauma training system for general surgery residents.

Davis JS, Garcia GD, Wyckoff MM, Alsafran S, Graygo JM, Withum KF, Levine RJ, Schulman CI.

Am J Surg. 2013 Jun;205(6):681-4. doi: 10.1016/j.amjsurg.2012.07.037. Epub 2013 Feb 4.

PMID:
23388423
7.

Evolution of end-of-life care at United States hospitals in the new millennium.

Lin RY, Levine RJ, Scanlan BC.

J Palliat Med. 2012 May;15(5):592-601. doi: 10.1089/jpm.2011.0432. Erratum in: J Palliat Med. 2012 Jun;15(6):726. Scanlon, Brian C [corrected to Scanlan, Brian C].

PMID:
22577786
8.

Angiogenic factors and the risk of adverse outcomes in women with suspected preeclampsia.

Rana S, Powe CE, Salahuddin S, Verlohren S, Perschel FH, Levine RJ, Lim KH, Wenger JB, Thadhani R, Karumanchi SA.

Circulation. 2012 Feb 21;125(7):911-9. doi: 10.1161/CIRCULATIONAHA.111.054361. Epub 2012 Jan 18.

9.

Overcoming burdens in the regulation of clinical research in children. Proceedings of a consensus conference, in historical context.

Levine RJ, Genel M, Cuttler L, Becker DJ, Nieman L, Rosenfield RL.

Int J Pediatr Endocrinol. 2011 Dec 30;2011(1):19. doi: 10.1186/1687-9856-2011-19.

10.

Circulating anti-angiogenic factors during hypertensive pregnancy and increased risk of respiratory distress syndrome in preterm neonates.

Wang A, Holston AM, Yu KF, Zhang J, Toporsian M, Karumanchi SA, Levine RJ.

J Matern Fetal Neonatal Med. 2012 Aug;25(8):1447-52. doi: 10.3109/14767058.2011.640368. Epub 2011 Dec 13.

11.

Folate and vitamin B12 in idiopathic male infertility.

Murphy LE, Mills JL, Molloy AM, Qian C, Carter TC, Strevens H, Wide-Swensson D, Giwercman A, Levine RJ.

Asian J Androl. 2011 Nov;13(6):856-61. doi: 10.1038/aja.2011.96. Epub 2011 Aug 22.

12.

Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease.

Powe CE, Levine RJ, Karumanchi SA.

Circulation. 2011 Jun 21;123(24):2856-69. doi: 10.1161/CIRCULATIONAHA.109.853127. Review. No abstract available.

13.

Social contexts influence ethical considerations of research.

Gordon JB, Levine RJ, Mazure CM, Rubin PE, Schaller BR, Young JL.

Am J Bioeth. 2011 May;11(5):24-30. doi: 10.1080/15265161.2011.560338.

PMID:
21534146
14.

Response to open peer commentaries on "Social contexts influence ethical considerations of research".

Levine RJ, Gordon JB, Mazure CM, Rubin PE, Schaller BR, Young JL.

Am J Bioeth. 2011 May;11(5):W1-2. doi: 10.1080/15265161.2011.576936. No abstract available.

PMID:
21534134
15.

Preeclampsia and the risk of large-for-gestational-age infants.

Powe CE, Ecker J, Rana S, Wang A, Ankers E, Ye J, Levine RJ, Karumanchi SA, Thadhani R.

Am J Obstet Gynecol. 2011 May;204(5):425.e1-6. doi: 10.1016/j.ajog.2010.12.030. Epub 2011 Mar 3.

16.

How does smoking reduce the risk of preeclampsia?

Karumanchi SA, Levine RJ.

Hypertension. 2010 May;55(5):1100-1. doi: 10.1161/HYPERTENSIONAHA.109.148973. Epub 2010 Mar 15. No abstract available.

17.

Pathogenesis of preeclampsia.

Young BC, Levine RJ, Karumanchi SA.

Annu Rev Pathol. 2010;5:173-92. doi: 10.1146/annurev-pathol-121808-102149. Review.

PMID:
20078220
18.

The interrelationship of complement-activation fragments and angiogenesis-related factors in early pregnancy and their association with pre-eclampsia.

Lynch AM, Murphy JR, Gibbs RS, Levine RJ, Giclas PC, Salmon JE, Holers VM.

BJOG. 2010 Mar;117(4):456-62. doi: 10.1111/j.1471-0528.2009.02473.x. Epub 2010 Jan 14.

19.

Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study.

Levine RJ, Vatten LJ, Horowitz GL, Qian C, Romundstad PR, Yu KF, Hollenberg AN, Hellevik AI, Asvold BO, Karumanchi SA.

BMJ. 2009 Nov 17;339:b4336. doi: 10.1136/bmj.b4336.

20.

Angiogenic factor abnormalities and fetal demise in a twin pregnancy.

Hladunewich MA, Steinberg G, Karumanchi SA, Levine RJ, Keating S, Kingdom J, Keunen J.

Nat Rev Nephrol. 2009 Nov;5(11):658-62. doi: 10.1038/nrneph.2009.154. Review.

PMID:
19855426
21.

Sperm chromatin structure assay as an independent predictor of fertility in vivo: a case-control study.

Giwercman A, Lindstedt L, Larsson M, Bungum M, Spano M, Levine RJ, Rylander L.

Int J Androl. 2010 Feb;33(1):e221-7. doi: 10.1111/j.1365-2605.2009.00995.x. Epub 2009 Oct 15.

PMID:
19840147
22.

Federal funding and the regulation of embryonic stem cell research: the Pontius Pilate maneuver.

Levine RJ.

Yale J Health Policy Law Ethics. 2009 Summer;9 Suppl:552-64. No abstract available.

PMID:
19757720
23.

The use of angiogenic biomarkers to differentiate non-HELLP related thrombocytopenia from HELLP syndrome.

Young B, Levine RJ, Salahuddin S, Qian C, Lim KH, Karumanchi SA, Rana S.

J Matern Fetal Neonatal Med. 2010 May;23(5):366-70. doi: 10.1080/14767050903184207.

24.

Ethical guidelines in pandemic influenza: recommendations of the Ethics Subcommittee of the Advisory Committee of the Director, Centers for Disease Control and Prevention.

Kinlaw K, Barrett DH, Levine RJ.

Disaster Med Public Health Prep. 2009 Dec;3 Suppl 2:S185-92. doi: 10.1097/DMP.0b013e3181ac194f.

PMID:
19675459
25.

Maternal serum theobromine and the development of preeclampsia.

Klebanoff MA, Zhang J, Zhang C, Levine RJ.

Epidemiology. 2009 Sep;20(5):727-32. doi: 10.1097/EDE.0b013e3181aba664.

PMID:
19535985
26.

First-trimester prediction of early preeclampsia: a possibility at last!

Levine RJ, Lindheimer MD.

Hypertension. 2009 May;53(5):747-8. doi: 10.1161/HYPERTENSIONAHA.109.129379. Epub 2009 Mar 9. No abstract available.

27.

Circulating angiogenic factors in gestational proteinuria without hypertension.

Holston AM, Qian C, Yu KF, Epstein FH, Karumanchi SA, Levine RJ.

Am J Obstet Gynecol. 2009 Apr;200(4):392.e1-10. doi: 10.1016/j.ajog.2008.10.033. Epub 2009 Jan 24.

28.

Circulating soluble endoglin and placental abruption.

Signore C, Mills JL, Qian C, Yu KF, Rana S, Karumanchi SA, Levine RJ.

Prenat Diagn. 2008 Sep;28(9):852-8. doi: 10.1002/pd.2065.

29.

Research involving adolescents as subjects : ethical considerations.

Levine RJ.

Ann N Y Acad Sci. 2008;1135:280-6. doi: 10.1196/annals.1429.039. Review.

PMID:
18574234
30.

A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate.

Romero R, Nien JK, Espinoza J, Todem D, Fu W, Chung H, Kusanovic JP, Gotsch F, Erez O, Mazaki-Tovi S, Gomez R, Edwin S, Chaiworapongsa T, Levine RJ, Karumanchi SA.

J Matern Fetal Neonatal Med. 2008 Jan;21(1):9-23. doi: 10.1080/14767050701830480.

31.

The dysregulation of human subjects research.

Fost N, Levine RJ.

JAMA. 2007 Nov 14;298(18):2196-8. No abstract available.

PMID:
18000206
32.
33.

Misclassification of maternal smoking status and its effects on an epidemiologic study of pregnancy outcomes.

England LJ, Grauman A, Qian C, Wilkins DG, Schisterman EF, Yu KF, Levine RJ.

Nicotine Tob Res. 2007 Oct;9(10):1005-13.

PMID:
17852766
34.

Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart.

Gupte RS, Vijay V, Marks B, Levine RJ, Sabbah HN, Wolin MS, Recchia FA, Gupte SA.

J Card Fail. 2007 Aug;13(6):497-506.

PMID:
17675065
35.

Seasonal variation in serum concentrations of reproductive hormones and urinary excretion of 6-sulfatoxymelatonin in men living north and south of the Arctic Circle: a longitudinal study.

Ruhayel Y, Malm G, Haugen TB, Henrichsen T, Bjørsvik C, Grotmol T, Saether T, Malm J, Figenschau Y, Rylander L, Levine RJ, Giwercman A.

Clin Endocrinol (Oxf). 2007 Jul;67(1):85-92. Epub 2007 Jun 4.

PMID:
17547693
36.

Sequential changes in antiangiogenic factors in early pregnancy and risk of developing preeclampsia.

Rana S, Karumanchi SA, Levine RJ, Venkatesha S, Rauh-Hain JA, Tamez H, Thadhani R.

Hypertension. 2007 Jul;50(1):137-42. Epub 2007 May 21.

PMID:
17515455
37.

The ethics of using quality improvement methods in health care.

Lynn J, Baily MA, Bottrell M, Jennings B, Levine RJ, Davidoff F, Casarett D, Corrigan J, Fox E, Wynia MK, Agich GJ, O'Kane M, Speroff T, Schyve P, Batalden P, Tunis S, Berlinger N, Cronenwett L, Fitzmaurice JM, Dubler NN, James B.

Ann Intern Med. 2007 May 1;146(9):666-73. Epub 2007 Apr 16.

PMID:
17438310
38.

Ethical issues in international vaccine research and development.

Levine RJ.

Yale J Biol Med. 2005 Oct;78(5):231-7. No abstract available.

39.

Angiogenic factors and preeclampsia.

Tjoa ML, Levine RJ, Karumanchi SA.

Front Biosci. 2007 Jan 1;12:2395-402. Review.

PMID:
17127249
40.

Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.

Levine RJ, Lam C, Qian C, Yu KF, Maynard SE, Sachs BP, Sibai BM, Epstein FH, Romero R, Thadhani R, Karumanchi SA; CPEP Study Group.

N Engl J Med. 2006 Sep 7;355(10):992-1005. Erratum in: N Engl J Med. 2006 Oct 26;355(17):1840.

41.

Empirical research to evaluate ethics committees' burdensome and perhaps unproductive policies and practices: a proposal.

Levine RJ.

J Empir Res Hum Res Ethics. 2006 Sep;1(3):1-4. doi: 10.1525/jer.2006.1.3.1.

PMID:
19385816
42.

Circulating angiogenic factors and placental abruption.

Signore C, Mills JL, Qian C, Yu K, Lam C, Epstein FH, Karumanchi SA, Levine RJ.

Obstet Gynecol. 2006 Aug;108(2):338-44. Erratum in: Obstet Gynecol. 2006 Oct;108(4):1035.

PMID:
16880304
43.

Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart.

Gupte SA, Levine RJ, Gupte RS, Young ME, Lionetti V, Labinskyy V, Floyd BC, Ojaimi C, Bellomo M, Wolin MS, Recchia FA.

J Mol Cell Cardiol. 2006 Aug;41(2):340-9. Epub 2006 Jul 7.

PMID:
16828794
44.

Serum sFlt1 concentration during preeclampsia and mid trimester blood pressure in healthy nulliparous women.

Levine RJ, Qian C, Maynard SE, Yu KF, Epstein FH, Karumanchi SA.

Am J Obstet Gynecol. 2006 Apr;194(4):1034-41.

PMID:
16580293
45.

Circulating angiogenic proteins in trisomy 13.

Bdolah Y, Palomaki GE, Yaron Y, Bdolah-Abram T, Goldman M, Levine RJ, Sachs BP, Haddow JE, Karumanchi SA.

Am J Obstet Gynecol. 2006 Jan;194(1):239-45.

PMID:
16389038
46.

Twenty-four-hour urine insulin as a measure of hyperinsulinaemia/insulin resistance before onset of pre-eclampsia and gestational hypertension.

Emery SP, Levine RJ, Qian C, Ewell MG, England LJ, Yu KF, Catalano PM; CPEP study group.

BJOG. 2005 Nov;112(11):1479-85.

47.

International codes of research ethics: current controversies and the future.

Levine RJ.

Indiana Law Rev. 2002;35(2):557-67. No abstract available.

PMID:
16189916
48.

Reflections on 'Rethinking research ethics'.

Levine RJ.

Am J Bioeth. 2005 Winter;5(1):1-3; author reply W15-8. No abstract available.

PMID:
16036649
49.

Investigative bronchoprovocation and bronchoscopy in airway diseases.

Busse WW, Wanner A, Adams K, Reynolds HY, Castro M, Chowdhury B, Kraft M, Levine RJ, Peters SP, Sullivan EJ.

Am J Respir Crit Care Med. 2005 Oct 1;172(7):807-16. Epub 2005 Jul 14. Review.

50.

Circulating angiogenic factors in preeclampsia.

Levine RJ, Karumanchi SA.

Clin Obstet Gynecol. 2005 Jun;48(2):372-86. Review. No abstract available.

PMID:
15805796

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