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Items: 1 to 50 of 3099

1.

Primary cilia defects causing mitral valve prolapse.

Toomer KA, Yu M, Fulmer D, Guo L, Moore KS, Moore R, Drayton KD, Glover J, Peterson N, Ramos-Ortiz S, Drohan A, Catching BJ, Stairley R, Wessels A, Lipschutz JH, Delling FN, Jeunemaitre X, Dina C, Collins RL, Brand H, Talkowski ME, Del Monte F, Mukherjee R, Awgulewitsch A, Body S, Hardiman G, Hazard ES, da Silveira WA, Wang B, Leyne M, Durst R, Markwald RR, Le Scouarnec S, Hagege A, Le Tourneau T, Kohl P, Rog-Zielinska EA, Ellinor PT, Levine RA, Milan DJ, Schott JJ, Bouatia-Naji N, Slaugenhaupt SA, Norris RA.

Sci Transl Med. 2019 May 22;11(493). pii: eaax0290. doi: 10.1126/scitranslmed.aax0290.

PMID:
31118289
2.

Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse.

Yu M, Georges A, Tucker NR, Kyryachenko S, Toomer K, Schott JJ, Delling FN, Fernandez-Friera L, Solis J, Ellinor PT, Levine RA, Slaugenhaupt SA, Hagège AA, Dina C, Jeunemaitre X, Milan DJ, Norris RA, Bouatia-Naji N.

Circ Genom Precis Med. 2019 May;12(5):e002497. doi: 10.1161/CIRCGEN.119.002497.

PMID:
31112420
3.

Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML.

Duy C, Teater M, Garrett-Bakelman FE, Lee TC, Meydan C, Glass JL, Li M, Hellmuth JC, Mohammad HP, Smitheman KN, Shih AH, Abdel-Wahab O, Tallman MS, Guzman ML, Muench D, Grimes HL, Roboz GJ, Kruger RG, Creasy CL, Paietta EM, Levine RL, Carroll M, Melnick AM.

Cancer Discov. 2019 May 10. pii: CD-19-0106. doi: 10.1158/2159-8290.CD-19-0106. [Epub ahead of print]

PMID:
31076479
4.

Identifying County-Level All-Cause Mortality Rate Trajectories and Their Spatial Distribution Across the United States.

Baltrus P, Malhotra K, Rust G, Levine R, Li C, Gaglioti AH.

Prev Chronic Dis. 2019 May 2;16:E55. doi: 10.5888/pcd16.180486.

5.

Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis.

Neri T, Hiriart E, van Vliet PP, Faure E, Norris RA, Farhat B, Jagla B, Lefrancois J, Sugi Y, Moore-Morris T, Zaffran S, Faustino RS, Zambon AC, Desvignes JP, Salgado D, Levine RA, de la Pompa JL, Terzic A, Evans SM, Markwald R, Pucéat M.

Nat Commun. 2019 Apr 26;10(1):1929. doi: 10.1038/s41467-019-09459-5.

6.

Racial Equality in Infant Outcomes: A Call to Action.

Brown Speights JS, Goldfarb SS, Levine RS, Rust G.

Am J Public Health. 2019 May;109(5):666-668. doi: 10.2105/AJPH.2019.305028. No abstract available.

PMID:
30969840
7.

Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.

Jeong JJ, Gu X, Nie J, Sundaravel S, Liu H, Kuo WL, Bhagat TD, Pradhan K, Cao J, Nischal S, McGraw KL, Bhattacharyya S, Bishop MR, Artz A, Thirman MJ, Moliterno A, Ji P, Levine RL, Godley LA, Steidl U, Bieker JJ, List AF, Saunthararajah Y, He C, Verma A, Wickrema A.

Cancer Discov. 2019 Apr 3. doi: 10.1158/2159-8290.CD-18-1138. [Epub ahead of print]

PMID:
30944118
8.

The Future of Oral Cancer Diagnosis: Merging Provider Awareness, Patient Education, and Technology to Achieve Early Detection.

Goldstein LB, Duong ML, Levine R, Dillenberg J.

Compend Contin Educ Dent. 2019 Apr;40(4):208-213; quiz 214.

PMID:
30938535
9.

Genetic and epigenetic determinants of AML pathogenesis.

Cai SF, Levine RL.

Semin Hematol. 2019 Apr;56(2):84-89. doi: 10.1053/j.seminhematol.2018.08.001. Epub 2018 Aug 22. Review.

PMID:
30926095
10.

Next-generation sequencing in the diagnosis and minimal residual disease assessment of acute myeloid leukemia.

Levine RL, Valk PJM.

Haematologica. 2019 May;104(5):868-871. doi: 10.3324/haematol.2018.205955. Epub 2019 Mar 28. No abstract available.

11.

Particulate and solubilized β-glucan and non-β-glucan fractions of Euglena gracilis induce pro-and anti-inflammatory innate immune cell responses and exhibit antioxidant properties.

Phillips FC, Jensen GS, Showman L, Tonda R, Horst G, Levine R.

J Inflamm Res. 2019 Mar 5;12:49-64. doi: 10.2147/JIR.S191824. eCollection 2019.

12.

A Practical Guide to Genome Editing Using Targeted Nuclease Technologies.

Porter SN, Levine RM, Pruett-Miller SM.

Compr Physiol. 2019 Mar 14;9(2):665-714. doi: 10.1002/cphy.c180022.

PMID:
30873595
13.

Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.

Chen D, Xia S, Wang M, Lin R, Li Y, Mao H, Aguiar M, Famulare CA, Shih AH, Brennan CW, Gao X, Pan Y, Liu S, Fan J, Jin L, Song L, Zhou A, Mukherjee J, Pieper RO, Mishra A, Peng J, Arellano M, Blum WG, Lonial S, Boggon TJ, Levine RL, Chen J.

Cancer Discov. 2019 Mar 12. doi: 10.1158/2159-8290.CD-18-1040. [Epub ahead of print]

PMID:
30862724
14.

Does the Flow Know? Mitral Regurgitant Jet Direction and Need for Valve Repair in Hypertrophic Obstructive Cardiomyopathy.

Schwammenthal E, Hagège AA, Levine RA.

J Am Soc Echocardiogr. 2019 Mar;32(3):341-343. doi: 10.1016/j.echo.2019.01.005. No abstract available.

PMID:
30827370
15.

Optimal Technique for Measurement of Linear Left Ventricular Dimensions.

Chetrit M, Roujol S, Picard MH, Timmins L, Manning WJ, Rudski LG, Levine RA, Afilalo J.

J Am Soc Echocardiogr. 2019 Apr;32(4):476-483.e1. doi: 10.1016/j.echo.2018.12.001. Epub 2019 Feb 28.

PMID:
30826223
16.

What Competencies are Needed to Run a Course or Clerkship?

Russo RA, Shankar R, Hilty D, Levine RE.

Acad Psychiatry. 2019 Jun;43(3):354-355. doi: 10.1007/s40596-019-01044-8. Epub 2019 Feb 28. No abstract available.

PMID:
30820846
17.

Impact of Mitral Regurgitation Severity and Cause on Effort Tolerance-Integrated Stress Myocardial Perfusion Imaging and Echocardiographic Assessment of Patients With Known or Suspected Coronary Artery Disease Undergoing Exercise Treadmill Testing.

Kampaktsis PN, Albert BJ, Kim J, Xie LX, Brouwer LR, Tehrani NH, Villanueva M, Choi DY, Szulc M, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW.

J Am Heart Assoc. 2019 Mar 5;8(5):e010974. doi: 10.1161/JAHA.118.010974.

18.

Women's Health Curricula in Internal Medicine Residency Programs: A Scoping Review.

Zhang CM, Insetta ER, Caufield-Noll C, Levine RB.

J Womens Health (Larchmt). 2019 Feb 22. doi: 10.1089/jwh.2018.7317. [Epub ahead of print]

PMID:
30794016
19.

Left ventricular geometry predicts optimal response to percutaneous mitral repair via MitraClip: Integrated assessment by two- and three-dimensional echocardiography.

Kim J, Alakbarli J, Palumbo MC, Xie LX, Rong LQ, Tehrani NH, Brouwer LR, Devereux RB, Wong SC, Bergman GW, Khalique OK, Levine RA, Ratcliffe MB, Weinsaft JW.

Catheter Cardiovasc Interv. 2019 May 1;93(6):1152-1160. doi: 10.1002/ccd.28147. Epub 2019 Feb 21.

PMID:
30790417
20.

Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.

Stivala S, Codilupi T, Brkic S, Baerenwaldt A, Ghosh N, Hao-Shen H, Dirnhofer S, Dettmer MS, Simillion C, Kaufmann BA, Chiu S, Keller M, Kleppe M, Hilpert M, Buser AS, Passweg JR, Radimerski T, Skoda RC, Levine RL, Meyer SC.

J Clin Invest. 2019 Mar 4;130:1596-1611. doi: 10.1172/JCI98785. eCollection 2019 Mar 4.

21.

Consecutive feedback-driven constitutional dynamic networks.

Yue L, Wang S, Wulf V, Lilienthal S, Remacle F, Levine RD, Willner I.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2843-2848. doi: 10.1073/pnas.1816670116. Epub 2019 Feb 6.

PMID:
30728303
22.

Per- and polyfluoroalkyl substances in two different populations of northern cardinals.

Russell MC, Newton SR, McClure KM, Levine RS, Phelps LP, Lindstrom AB, Strynar MJ.

Chemosphere. 2019 May;222:295-304. doi: 10.1016/j.chemosphere.2019.01.112. Epub 2019 Jan 22.

PMID:
30710759
23.

Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis.

Loberg MA, Bell RK, Goodwin LO, Eudy E, Miles LA, SanMiguel JM, Young K, Bergstrom DE, Levine RL, Schneider RK, Trowbridge JJ.

Leukemia. 2019 Jan 28. doi: 10.1038/s41375-018-0368-6. [Epub ahead of print]

PMID:
30692594
24.

Insights into the mechanism of paradoxical low-flow, low-pressure gradient severe aortic stenosis: association with reduced O2 consumption by the whole body.

Onoue T, Iwataki M, Araki M, Itoh H, Isotani A, Umeda H, Fukuda S, Nagata Y, Tsuda Y, Fujino Y, Hanyu M, Ando K, Shirai S, Takeuchi M, Saeki S, Levine RA, Otsuji Y.

Am J Physiol Heart Circ Physiol. 2019 Apr 1;316(4):H840-H848. doi: 10.1152/ajpheart.00715.2018. Epub 2019 Jan 25.

PMID:
30681367
25.

Atrial Fibrillation and Mitral Valve Prolapse: Time to Intervene?

Borger MA, Mansour MC, Levine RA.

J Am Coll Cardiol. 2019 Jan 29;73(3):275-277. doi: 10.1016/j.jacc.2018.11.018. No abstract available.

PMID:
30678756
26.

Protecting User Privacy and Rights in Academic Data-Sharing Partnerships: Principles From a Pilot Program at Crisis Text Line.

Pisani AR, Kanuri N, Filbin B, Gallo C, Gould M, Lehmann LS, Levine R, Marcotte JE, Pascal B, Rousseau D, Turner S, Yen S, Ranney ML.

J Med Internet Res. 2019 Jan 17;21(1):e11507. doi: 10.2196/11507.

27.

Left Ventricular Dyssynchrony and the Mitral Valve Apparatus: An Orchestra That Needs to Play in Sync.

Levine RA, Nagata Y, Dal-Bianco JP.

JACC Cardiovasc Imaging. 2019 Jan 9. pii: S1936-878X(18)30636-3. doi: 10.1016/j.jcmg.2018.07.008. [Epub ahead of print] No abstract available.

PMID:
30660517
28.

Unfolding the Role of Calreticulin in Myeloproliferative Neoplasm Pathogenesis.

Merlinsky TR, Levine RL, Pronier E.

Clin Cancer Res. 2019 May 15;25(10):2956-2962. doi: 10.1158/1078-0432.CCR-18-3777. Epub 2019 Jan 17. Review.

PMID:
30655313
29.

Impact of High-Molecular-Risk Mutations on Transplantation Outcomes in Patients with Myelofibrosis.

Tamari R, Rapaport F, Zhang N, McNamara C, Kuykendall A, Sallman DA, Komrokji R, Arruda A, Najfeld V, Sandy L, Medina J, Litvin R, Famulare CA, Patel MA, Maloy M, Castro-Malaspina H, Giralt SA, Weinberg RS, Mascarenhas JO, Mesa R, Rondelli D, Dueck AC, Levine RL, Gupta V, Hoffman R, Rampal RK.

Biol Blood Marrow Transplant. 2019 Jan 6. pii: S1083-8791(19)30005-9. doi: 10.1016/j.bbmt.2019.01.002. [Epub ahead of print]

PMID:
30625392
30.

Linking beaver dam affected flow dynamics to upstream passage of Arctic grayling.

Cutting KA, Ferguson JM, Anderson ML, Cook K, Davis SC, Levine R.

Ecol Evol. 2018 Dec 4;8(24):12905-12917. doi: 10.1002/ece3.4728. eCollection 2018 Dec.

31.

Reliability and between-group stability of a health-related quality of life symptom index for persons with anal high-grade squamous intraepithelial lesions: an AIDS Malignancy Consortium Study (AMC-A03).

Atkinson TM, Palefsky J, Li Y, Webb A, Berry JM, Goldstone S, Levine R, Wilkin TJ, Bucher G, Cella D, Burkhalter JE; ANCHOR HRQoL Implementation Group.

Qual Life Res. 2019 May;28(5):1265-1269. doi: 10.1007/s11136-018-2089-8. Epub 2019 Jan 7.

PMID:
30617704
32.

An evaluation of the "BE NICE Champion" programme: A bullying intervention programme for registered nurses.

Keller R, Allie T, Levine R.

J Nurs Manag. 2019 May;27(4):758-764. doi: 10.1111/jonm.12748. Epub 2019 Feb 20.

PMID:
30615232
33.

Building Leadership Capacity for Mission Execution in a Large Academic Department of Medicine.

Golden SH, Bass E, Berry S, Biddison LD, Cayea D, Crews D, Desai S, Ghanem KG, Herzke C, Kirk G, Kisuule F, Levine R, Marr K, O'Rourke B, Pasricha P, Peairs K, Ray S, Durso SC, Hellmann D, Anderson ME.

Am J Med. 2019 Apr;132(4):535-543. doi: 10.1016/j.amjmed.2018.12.003. Epub 2018 Dec 24. No abstract available.

PMID:
30590014
34.

Possible mechanism of late systolic mitral valve prolapse: systolic superior shift of leaflets secondary to annular dilatation that causes papillary muscle traction.

Hei S, Iwataki M, Jang JY, Kuwaki H, Mahara K, Fukuda S, Kim YJ, Nabeshima Y, Onoue T, Nagata Y, Nishino S, Watanabe N, Takeuchi M, Nishimura Y, Song JK, Levine RA, Otsuji Y.

Am J Physiol Heart Circ Physiol. 2019 Mar 1;316(3):H629-H638. doi: 10.1152/ajpheart.00618.2018. Epub 2018 Dec 21.

PMID:
30575434
35.

Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 V617F Mice.

Wang W, Liu W, Fidler T, Wang Y, Tang Y, Woods B, Welch C, Cai B, Silvestre-Roig C, Ai D, Yang YG, Hidalgo A, Soehnlein O, Tabas I, Levine RL, Tall AR, Wang N.

Circ Res. 2018 Nov 9;123(11):e35-e47. doi: 10.1161/CIRCRESAHA.118.313283.

PMID:
30571460
36.

Safety and efficacy of combined ruxolitinib and decitabine in accelerated and blast-phase myeloproliferative neoplasms.

Rampal RK, Mascarenhas JO, Kosiorek HE, Price L, Berenzon D, Hexner E, Abboud CN, Kremyanskaya M, Weinberg RS, Salama ME, Menghrajani K, Najfeld V, Sandy L, Heaney ML, Levine RL, Mesa RA, Dueck AC, Goldberg JD, Hoffman R.

Blood Adv. 2018 Dec 26;2(24):3572-3580. doi: 10.1182/bloodadvances.2018019661.

37.

New Mitral Valve Annuloplasty Concept: Optimizing Annular Dynamics and Force Distribution.

Jensen MO, Jensen H, Skov SN, Levine RA, Nygaard H, M Hasenkam J, Nielsen SL.

J Heart Valve Dis. 2018 Jan;27(1):38-46.

PMID:
30560598
38.

Loss of plasmacytoid dendritic cell differentiation is highly predictive for post-induction measurable residual disease and inferior outcomes in acute myeloid leukemia.

Xiao W, Goldberg AD, Famulare C, Devlin S, Nguyen N, Sim S, Kabel CC, Patel MA, McGovern E, Patel A, Schulman J, Dunbar A, Epstein-Peterson ZD, Menghrajani K, Getta BM, Cai SF, Geyer MB, Glass J, Taylor J, Viny AD, Levine RL, Zhang Y, Giralt S, Klimek V, Tallman MS, Roshal M.

Haematologica. 2018 Dec 6. pii: haematol.2018.203018. doi: 10.3324/haematol.2018.203018. [Epub ahead of print]

39.

PHF6 and DNMT3A mutations are enriched in distinct subgroups of mixed phenotype acute leukemia with T-lineage differentiation.

Xiao W, Bharadwaj M, Levine M, Farnhoud N, Pastore F, Getta BM, Hultquist A, Famulare C, Medina JS, Patel MA, Gao Q, Lewis N, Pichardo J, Baik J, Shaffer B, Giralt S, Rampal R, Devlin S, Cimera R, Zhang Y, E Arcila M, Papaemmanuil E, Levine RL, Roshal M.

Blood Adv. 2018 Dec 11;2(23):3526-3539. doi: 10.1182/bloodadvances.2018023531. Erratum in: Blood Adv. 2019 Apr 9;3(7):956.

40.

Drosophila methionine sulfoxide reductase A (MSRA) lacks methionine oxidase activity.

Tarafdar S, Kim G, Levine RL.

Free Radic Biol Med. 2019 Feb 1;131:154-161. doi: 10.1016/j.freeradbiomed.2018.12.001. Epub 2018 Dec 4.

PMID:
30529269
41.

Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib.

Stein EM, DiNardo CD, Fathi AT, Pollyea DA, Stone RM, Altman JK, Roboz GJ, Patel MR, Collins R, Flinn IW, Sekeres MA, Stein AS, Kantarjian HM, Levine RL, Vyas P, MacBeth KJ, Tosolini A, VanOostendorp J, Xu Q, Gupta I, Lila T, Risueno A, Yen KE, Wu B, Attar EC, Tallman MS, de Botton S.

Blood. 2019 Feb 14;133(7):676-687. doi: 10.1182/blood-2018-08-869008. Epub 2018 Dec 3.

42.

Effects of beta-1,3-glucan (AletaTM) on vaccination response in broiler chickens.

Horst G, Levine R, Chick R, Hofacre C.

Poult Sci. 2019 Apr 1;98(4):1643-1647. doi: 10.3382/ps/pey523.

PMID:
30476311
43.

Difficult Patient Encounters: Assessing Pediatric Residents' Communication Skills Training Needs.

Collins K, Hopkins A, Shilkofski NA, Levine RB, Hernandez RG.

Cureus. 2018 Sep 21;10(9):e3340. doi: 10.7759/cureus.3340.

44.

Extramedullary acute myeloid leukemia presenting in young adults demonstrates sensitivity to high-dose anthracycline: a subset analysis from ECOG-ACRIN 1900.

Fernandez HF, Sun Z, Litzow MR, Luger SM, Paietta E, Racevskis J, Levine RL, Patel JP, Abdel-Wahab O, Ketterling RP, Dewald GW, Bennett JM, Rowe JM, Lazarus HM, Tallman MS.

Haematologica. 2019 Apr;104(4):e147-e150. doi: 10.3324/haematol.2018.197277. Epub 2018 Nov 22. No abstract available.

45.

A nationwide study of breast cancer, depression, and multimorbidity among hospitalized women and men in the United States.

Zoorob RJ, Salemi JL, Mejia de Grubb MC, Modak S, Levine RS.

Breast Cancer Res Treat. 2019 Feb;174(1):237-248. doi: 10.1007/s10549-018-5059-5. Epub 2018 Nov 21.

PMID:
30465155
46.

Tissue-based markers of right ventricular dysfunction in ischemic mitral regurgitation assessed via stress cardiac magnetic resonance and three-dimensional echocardiography.

Kim J, Alakbarli J, Yum B, Tehrani NH, Pollie MP, Abouzeid C, Di Franco A, Ratcliffe MB, Poppas A, Levine RA, Devereux RB, Weinsaft JW.

Int J Cardiovasc Imaging. 2019 Apr;35(4):683-693. doi: 10.1007/s10554-018-1500-4. Epub 2018 Nov 20.

PMID:
30460581
47.

Targeting the CALR interactome in myeloproliferative neoplasms.

Pronier E, Cifani P, Merlinsky TR, Berman KB, Somasundara AVH, Rampal RK, LaCava J, Wei KE, Pastore F, Maag JL, Park J, Koche R, Kentsis A, Levine RL.

JCI Insight. 2018 Nov 15;3(22). pii: 122703. doi: 10.1172/jci.insight.122703.

48.

Managing Clonal Hematopoiesis in Patients With Solid Tumors.

Bolton KL, Gillis NK, Coombs CC, Takahashi K, Zehir A, Bejar R, Garcia-Manero G, Futreal A, Jensen BC, Diaz LA Jr, Gupta D, Mantha S, Klimek V, Papaemmanuil E, Levine R, Padron E.

J Clin Oncol. 2019 Jan 1;37(1):7-11. doi: 10.1200/JCO.18.00331. Epub 2018 Nov 7. No abstract available.

PMID:
30403571
49.

Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition.

Harding JJ, Lowery MA, Shih AH, Schvartzman JM, Hou S, Famulare C, Patel M, Roshal M, Do RK, Zehir A, You D, Selcuklu SD, Viale A, Tallman MS, Hyman DM, Reznik E, Finley LWS, Papaemmanuil E, Tosolini A, Frattini MG, MacBeth KJ, Liu G, Fan B, Choe S, Wu B, Janjigian YY, Mellinghoff IK, Diaz LA, Levine RL, Abou-Alfa GK, Stein EM, Intlekofer AM.

Cancer Discov. 2018 Dec;8(12):1540-1547. doi: 10.1158/2159-8290.CD-18-0877. Epub 2018 Oct 24.

PMID:
30355724
50.

Cicatrizing Blepharoconjunctivitis Occurring During Dupilumab Treatment and a Proposed Algorithm for Its Management.

Levine RM, Tattersall IW, Gaudio PA, King BA.

JAMA Dermatol. 2018 Dec 1;154(12):1485-1486. doi: 10.1001/jamadermatol.2018.3427. No abstract available.

PMID:
30347029

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