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Items: 46

1.

Myosteatosis is associated with poor physical fitness in patients undergoing hepatopancreatobiliary surgery.

West MA, van Dijk DPJ, Gleadowe F, Reeves T, Primrose JN, Abu Hilal M, Edwards MR, Jack S, Rensen SSS, Grocott MPW, Levett DZH, Olde Damink SWM.

J Cachexia Sarcopenia Muscle. 2019 May 21. doi: 10.1002/jcsm.12433. [Epub ahead of print]

2.

Metabolomic and lipidomic plasma profile changes in human participants ascending to Everest Base Camp.

O'Brien KA, Atkinson RA, Richardson L, Koulman A, Murray AJ, Harridge SDR, Martin DS, Levett DZH, Mitchell K, Mythen MG, Montgomery HE, Grocott MPW, Griffin JL, Edwards LM.

Sci Rep. 2019 Feb 19;9(1):2297. doi: 10.1038/s41598-019-38832-z.

3.

Exercise prehabilitation may lead to augmented tumor regression following neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

West MA, Astin R, Moyses HE, Cave J, White D, Levett DZH, Bates A, Brown G, Grocott MPW, Jack S.

Acta Oncol. 2019 May;58(5):588-595. doi: 10.1080/0284186X.2019.1566775. Epub 2019 Feb 6.

PMID:
30724668
4.

Psychological factors, prehabilitation and surgical outcomes: evidence and future directions.

Levett DZH, Grimmett C.

Anaesthesia. 2019 Jan;74 Suppl 1:36-42. doi: 10.1111/anae.14507. Review.

PMID:
30604423
5.

Correction to: Cardiopulmonary exercise testing (CPET) in the United Kingdom-a national survey of the structure, conduct, interpretation and funding.

Reeves T, Bates S, Sharp T, Richardson K, Bali S, Plumb J, Anderson H, Prentis J, Swart M, Levett DZH; Perioperative Exercise Testing and Training Society (POETTS).

Perioper Med (Lond). 2018 May 4;7:8. doi: 10.1186/s13741-018-0087-6. eCollection 2018.

6.

Tricks of the trade: delivering reliable healthcare.

Levett DZH, Grocott MPW.

Anaesthesia. 2018 Jun;73(6):671-674. doi: 10.1111/anae.14242. Epub 2018 Mar 26. No abstract available.

7.

Perioperative cardiopulmonary exercise testing (CPET): consensus clinical guidelines on indications, organization, conduct, and physiological interpretation.

Levett DZH, Jack S, Swart M, Carlisle J, Wilson J, Snowden C, Riley M, Danjoux G, Ward SA, Older P, Grocott MPW; Perioperative Exercise Testing and Training Society (POETTS).

Br J Anaesth. 2018 Mar;120(3):484-500. doi: 10.1016/j.bja.2017.10.020. Epub 2017 Nov 24.

8.

Inter-observer reliability of preoperative cardiopulmonary exercise test interpretation: a cross-sectional study.

Abbott TEF, Gooneratne M, McNeill J, Lee A, Levett DZH, Grocott MPW, Swart M, MacDonald N; ARCTIC study investigators.

Br J Anaesth. 2018 Mar;120(3):475-483. doi: 10.1016/j.bja.2017.11.071. Epub 2017 Nov 29.

9.

Cardiopulmonary exercise testing (CPET) in the United Kingdom-a national survey of the structure, conduct, interpretation and funding.

Reeves T, Bates S, Sharp T, Richardson K, Bali S, Plumb J, Anderson H, Prentis J, Swart M, Levett DZH; Perioperative Exercise Testing and Training Society (POETTS).

Perioper Med (Lond). 2018 Jan 26;7:2. doi: 10.1186/s13741-017-0082-3. eCollection 2018. Erratum in: Perioper Med (Lond). 2018 May 4;7:8.

10.

Fit for surgery? Perspectives on preoperative exercise testing and training.

Richardson K, Levett DZH, Jack S, Grocott MPW.

Br J Anaesth. 2017 Dec 1;119(suppl_1):i34-i43. doi: 10.1093/bja/aex393. Review.

11.

TCA cycle rewiring fosters metabolic adaptation to oxygen restriction in skeletal muscle from rodents and humans.

Capitanio D, Fania C, Torretta E, Viganò A, Moriggi M, Bravatà V, Caretti A, Levett DZH, Grocott MPW, Samaja M, Cerretelli P, Gelfi C.

Sci Rep. 2017 Aug 29;7(1):9723. doi: 10.1038/s41598-017-10097-4.

12.

Re-designing the pathway to surgery: better care and added value.

Grocott MPW, Plumb JOM, Edwards M, Fecher-Jones I, Levett DZH.

Perioper Med (Lond). 2017 Jun 20;6:9. doi: 10.1186/s13741-017-0065-4. eCollection 2017.

13.

Exercise Testing, Supplemental Oxygen, and Hypoxia.

Ward SA, Grocott MPW, Levett DZH.

Ann Am Thorac Soc. 2017 Jul;14(Supplement_1):S140-S148. doi: 10.1513/AnnalsATS.201701-043OT. Review.

PMID:
28590162
14.

Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition.

Wandrag L, Siervo M, Riley HL, Khosravi M, Fernandez BO, Leckstrom CA, Martin DS, Mitchell K, Levett DZH, Montgomery HE, Mythen MG, Stroud MA, Grocott MPW, Feelisch M; Caudwell Xtreme Everest Research Group.

Redox Biol. 2017 Oct;13:60-68. doi: 10.1016/j.redox.2017.05.004. Epub 2017 May 8.

15.

Metabolic basis to Sherpa altitude adaptation.

Horscroft JA, Kotwica AO, Laner V, West JA, Hennis PJ, Levett DZH, Howard DJ, Fernandez BO, Burgess SL, Ament Z, Gilbert-Kawai ET, Vercueil A, Landis BD, Mitchell K, Mythen MG, Branco C, Johnson RS, Feelisch M, Montgomery HE, Griffin JL, Grocott MPW, Gnaiger E, Martin DS, Murray AJ.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6382-6387. doi: 10.1073/pnas.1700527114. Epub 2017 May 22.

16.

Cardiopulmonary Exercise Testing and Surgery.

Older PO, Levett DZH.

Ann Am Thorac Soc. 2017 Jul;14(Supplement_1):S74-S83. doi: 10.1513/AnnalsATS.201610-780FR. Review.

PMID:
28511024
17.

Preparing the patient for surgery to improve outcomes.

Levett DZ, Edwards M, Grocott M, Mythen M.

Best Pract Res Clin Anaesthesiol. 2016 Jun;30(2):145-57. doi: 10.1016/j.bpa.2016.04.002. Epub 2016 Apr 27. Review.

PMID:
27396803
18.

Caudwell Xtreme Everest: An Overview.

Grocott MP, Levett DZ, Martin DS, Wilson MH, Mackenney A, Dhillon S, Montgomery HE, Mythen MG, Mitchell K.

Adv Exp Med Biol. 2016;903:427-37. doi: 10.1007/978-1-4899-7678-9_28. Review.

PMID:
27343112
19.

Cardiopulmonary exercise testing for risk prediction in major abdominal surgery.

Levett DZ, Grocott MP.

Anesthesiol Clin. 2015 Mar;33(1):1-16. doi: 10.1016/j.anclin.2014.11.001. Review.

PMID:
25701925
20.

Genetic factors associated with exercise performance in atmospheric hypoxia.

Hennis PJ, O'Doherty AF, Levett DZ, Grocott MP, Montgomery HM.

Sports Med. 2015 May;45(5):745-61. doi: 10.1007/s40279-015-0309-8. Review.

21.

Cardiopulmonary exercise testing, prehabilitation, and Enhanced Recovery After Surgery (ERAS).

Levett DZ, Grocott MP.

Can J Anaesth. 2015 Feb;62(2):131-42. doi: 10.1007/s12630-014-0307-6. Epub 2015 Jan 22. Review.

22.

Changes in muscle proteomics in the course of the Caudwell Research Expedition to Mt. Everest.

Levett DZ, Viganò A, Capitanio D, Vasso M, De Palma S, Moriggi M, Martin DS, Murray AJ, Cerretelli P, Grocott MP, Gelfi C.

Proteomics. 2015 Jan;15(1):160-71. doi: 10.1002/pmic.201400306. Epub 2014 Dec 4.

PMID:
25370915
23.

Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco-insular regulation: the not-so-sweet price for good regulation.

Siervo M, Riley HL, Fernandez BO, Leckstrom CA, Martin DS, Mitchell K, Levett DZ, Montgomery HE, Mythen MG, Grocott MP, Feelisch M; Caudwell Xtreme Everest Research Group.

PLoS One. 2014 Apr 14;9(4):e94915. doi: 10.1371/journal.pone.0094915. eCollection 2014.

24.

Oral Coenzyme Q10 supplementation does not prevent cardiac alterations during a high altitude trek to everest base cAMP.

Holloway CJ, Murray AJ, Mitchell K, Martin DS, Johnson AW, Cochlin LE, Codreanu I, Dhillon S, Rodway GW, Ashmore T, Levett DZ, Neubauer S, Montgomery HE, Grocott MP, Clarke K; Caudwell Xtreme Everest 2009 Investigators.

High Alt Med Biol. 2014 Dec;15(4):459-67. doi: 10.1089/ham.2013.1053.

25.

Everest 60 years on: what next?

Grocott MP, Levett DZh.

Extrem Physiol Med. 2013 Jun 6;2(1):20. doi: 10.1186/2046-7648-2-20.

26.

Xtreme Everest 2: unlocking the secrets of the Sherpa phenotype?

Martin DS, Gilbert-Kawai E, Levett DZh, Mitchell K, Kumar Bc R, Mythen MG, Grocott MP.

Extrem Physiol Med. 2013 Oct 23;2(1):30. doi: 10.1186/2046-7648-2-30.

27.

The use of skeletal muscle near infrared spectroscopy and a vascular occlusion test at high altitude.

Martin DS, Levett DZ, Bezemer R, Montgomery HE, Grocott MP; Caudwell Xtreme Everest Research Group.

High Alt Med Biol. 2013 Sep;14(3):256-62. doi: 10.1089/ham.2012.1109.

28.

Design and conduct of 'Xtreme Alps': a double-blind, randomised controlled study of the effects of dietary nitrate supplementation on acclimatisation to high altitude.

Martin DS, Gilbert-Kawai ET, Meale PM, Fernandez BO, Cobb A, Khosravi M, Mitchell K, Grocott MP, Levett DZ, Mythen MG, Feelisch M; Xtreme Alps Research Group.

Contemp Clin Trials. 2013 Nov;36(2):450-9. doi: 10.1016/j.cct.2013.09.002. Epub 2013 Sep 10.

29.

The Young Everest Study: preliminary report of changes in sleep and cerebral blood flow velocity during slow ascent to altitude in unacclimatised children.

Gavlak JC, Stocks J, Laverty A, Fettes E, Bucks R, Sonnappa S, Cooper J, Grocott MP, Levett DZ, Martin DS, Imray CH, Kirkham FJ.

Arch Dis Child. 2013 May;98(5):356-62. doi: 10.1136/archdischild-2012-302512. Epub 2013 Mar 7.

30.

The role of nitrogen oxides in human adaptation to hypoxia.

Levett DZ, Fernandez BO, Riley HL, Martin DS, Mitchell K, Leckstrom CA, Ince C, Whipp BJ, Mythen MG, Montgomery HE, Grocott MP, Feelisch M; Caudwell Extreme Everest Research Group.

Sci Rep. 2011;1:109. doi: 10.1038/srep00109. Epub 2011 Oct 6.

31.

Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest.

Levett DZ, Radford EJ, Menassa DA, Graber EF, Morash AJ, Hoppeler H, Clarke K, Martin DS, Ferguson-Smith AC, Montgomery HE, Grocott MP, Murray AJ; Caudwell Xtreme Everest Research Group.

FASEB J. 2012 Apr;26(4):1431-41. doi: 10.1096/fj.11-197772. Epub 2011 Dec 20.

PMID:
22186874
32.

Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia--an ultrasound and MRI study.

Wilson MH, Edsell ME, Davagnanam I, Hirani SP, Martin DS, Levett DZ, Thornton JS, Golay X, Strycharczuk L, Newman SP, Montgomery HE, Grocott MP, Imray CH; Caudwell Xtreme Everest Research Group.

J Cereb Blood Flow Metab. 2011 Oct;31(10):2019-29. doi: 10.1038/jcbfm.2011.81. Epub 2011 Jun 8.

33.

Stroke at high altitude diagnosed in the field using portable ultrasound.

Wilson MH, Levett DZ, Dhillon S, Mitchell K, Morgan J, Grocott MP, Imray C.

Wilderness Environ Med. 2011 Mar;22(1):54-7. doi: 10.1016/j.wem.2010.10.007. Epub 2010 Oct 29.

PMID:
21377120
34.

Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp.

Holloway CJ, Montgomery HE, Murray AJ, Cochlin LE, Codreanu I, Hopwood N, Johnson AW, Rider OJ, Levett DZ, Tyler DJ, Francis JM, Neubauer S, Grocott MP, Clarke K; Caudwell Xtreme Everest Research Group.

FASEB J. 2011 Feb;25(2):792-6. doi: 10.1096/fj.10-172999. Epub 2010 Oct 26.

PMID:
20978235
35.

Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia.

Levett DZ, Martin DS, Wilson MH, Mitchell K, Dhillon S, Rigat F, Montgomery HE, Mythen MG, Grocott MP; Caudwell Xtreme Everest Research Group.

BMC Med Res Methodol. 2010 Oct 21;10:98. doi: 10.1186/1471-2288-10-98.

36.

Resting and exercising cardiorespiratory variables and acute mountain sickness.

Hooper TJ, Levett DZ, Mellor AJ, Grocott MP.

J R Nav Med Serv. 2010;96(1):6-12.

PMID:
20608004
37.

Caudwell xtreme Everest expedition.

Grocott MP, Martin DS, Wilson MH, Mitchell K, Dhillon S, Mythen MG, Montgomery HE, Levett DZ; Caudwell Xtreme Everest Research Group.

High Alt Med Biol. 2010 Summer;11(2):133-7. doi: 10.1089/ham.2009.1093.

PMID:
20586597
38.

Changes in sublingual microcirculatory flow index and vessel density on ascent to altitude.

Martin DS, Goedhart P, Vercueil A, Ince C, Levett DZ, Grocott MP; Caudwell Xtreme Everest Research Group.

Exp Physiol. 2010 Aug;95(8):880-91. doi: 10.1113/expphysiol.2009.051656. Epub 2010 Apr 23.

39.

Changes in skeletal muscle oxygenation during exercise measured by near-infrared spectroscopy on ascent to altitude.

Martin DS, Levett DZ, Mythen M, Grocott MP; Caudwell Xtreme Everest Research Group.

Crit Care. 2009;13 Suppl 5:S7. doi: 10.1186/cc8005. Epub 2009 Nov 30.

40.

Variation in human performance in the hypoxic mountain environment.

Martin DS, Levett DZ, Grocott MP, Montgomery HE.

Exp Physiol. 2010 Mar;95(3):463-70. doi: 10.1113/expphysiol.2009.047589. Epub 2009 Nov 27. Review.

41.

The Young Everest Study: effects of hypoxia at high altitude on cardiorespiratory function and general well-being in healthy children.

Scrase E, Laverty A, Gavlak JC, Sonnappa S, Levett DZ, Martin D, Grocott MP, Stocks J.

Arch Dis Child. 2009 Aug;94(8):621-6. doi: 10.1136/adc.2008.150516. Epub 2009 Apr 23.

PMID:
19395400
42.

Abnormal blood flow in the sublingual microcirculation at high altitude.

Martin DS, Ince C, Goedhart P, Levett DZ, Grocott MP; Caudwell Xtreme Everest Research Group.

Eur J Appl Physiol. 2009 Jun;106(3):473-8. doi: 10.1007/s00421-009-1023-8. Epub 2009 Mar 31.

43.

Arterial blood gases and oxygen content in climbers on Mount Everest.

Grocott MP, Martin DS, Levett DZ, McMorrow R, Windsor J, Montgomery HE; Caudwell Xtreme Everest Research Group.

N Engl J Med. 2009 Jan 8;360(2):140-9. doi: 10.1056/NEJMoa0801581.

44.

Bubble trouble: a review of diving physiology and disease.

Levett DZ, Millar IL.

Postgrad Med J. 2008 Nov;84(997):571-8. doi: 10.1136/pgmj.2008.068320. Review.

PMID:
19103814
45.

The Postoperative Morbidity Survey was validated and used to describe morbidity after major surgery.

Grocott MP, Browne JP, Van der Meulen J, Matejowsky C, Mutch M, Hamilton MA, Levett DZ, Emberton M, Haddad FS, Mythen MG.

J Clin Epidemiol. 2007 Sep;60(9):919-28. Epub 2007 May 7.

PMID:
17689808
46.

ASA scores in the preoperative patient: feedback to clinicians can improve data quality.

Grocott MP, Levett DZ, Matejowsky C, Emberton M, Mythen MG.

J Eval Clin Pract. 2007 Apr;13(2):318-9. No abstract available.

PMID:
17378882

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