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Items: 1 to 50 of 68

1.

Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock.

Vogt JA, Wachter U, Wagner K, Calzia E, Gröger M, Weber S, Stahl B, Georgieff M, Asfar P, Fontaine E, Radermacher P, Leverve XM, Wagner F.

Intensive Care Med Exp. 2014 Dec;2(1):19. doi: 10.1186/2197-425X-2-19. Epub 2014 Jun 3.

2.

Early resuscitation of dengue shock syndrome in children with hyperosmolar sodium-lactate: a randomized single-blind clinical trial of efficacy and safety.

Somasetia DH, Setiati TE, Sjahrodji AM, Idjradinata PS, Setiabudi D, Roth H, Ichai C, Fontaine E, Leverve XM.

Crit Care. 2014 Sep 5;18(5):466. doi: 10.1186/s13054-014-0466-4.

3.

Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial.

Ichai C, Payen JF, Orban JC, Quintard H, Roth H, Legrand R, Francony G, Leverve XM.

Intensive Care Med. 2013 Aug;39(8):1413-22. doi: 10.1007/s00134-013-2978-9. Epub 2013 Jun 8.

PMID:
23749153
4.

Reactive oxygen species are produced at low glucose and contribute to the activation of AMPK in insulin-secreting cells.

Sarre A, Gabrielli J, Vial G, Leverve XM, Assimacopoulos-Jeannet F.

Free Radic Biol Med. 2012 Jan 1;52(1):142-50. doi: 10.1016/j.freeradbiomed.2011.10.437. Epub 2011 Oct 18.

5.

Effects of a high-fat diet on energy metabolism and ROS production in rat liver.

Vial G, Dubouchaud H, Couturier K, Cottet-Rousselle C, Taleux N, Athias A, Galinier A, Casteilla L, Leverve XM.

J Hepatol. 2011 Feb;54(2):348-56. doi: 10.1016/j.jhep.2010.06.044. Epub 2010 Sep 7.

PMID:
21109325
6.

Liver mitochondria and insulin resistance.

Vial G, Dubouchaud H, Leverve XM.

Acta Biochim Pol. 2010;57(4):389-92. Epub 2010 Nov 16. Review.

7.

High expression of thyroid hormone receptors and mitochondrial glycerol-3-phosphate dehydrogenase in the liver is linked to enhanced fatty acid oxidation in Lou/C, a rat strain resistant to obesity.

Taleux N, Guigas B, Dubouchaud H, Moreno M, Weitzel JM, Goglia F, Favier R, Leverve XM.

J Biol Chem. 2009 Feb 13;284(7):4308-16. doi: 10.1074/jbc.M806187200. Epub 2008 Dec 2.

8.

[Metformin and type 2 diabetes: the UKPDS experience].

Leverve XM.

Journ Annu Diabetol Hotel Dieu. 2007:5-11. French. No abstract available.

PMID:
18610755
9.

Half-molar sodium-lactate solution has a beneficial effect in patients after coronary artery bypass grafting.

Leverve XM, Boon C, Hakim T, Anwar M, Siregar E, Mustafa I.

Intensive Care Med. 2008 Oct;34(10):1796-803. doi: 10.1007/s00134-008-1165-x. Epub 2008 Jun 18.

PMID:
18563389
10.

Intradialytic nutritional support.

Cano NJ, Leverve XM.

Curr Opin Clin Nutr Metab Care. 2008 Mar;11(2):147-51. doi: 10.1097/MCO.0b013e3282f44c1b. Review.

PMID:
18301090
11.

To cope with oxygen: a long and still tumultuous story for life.

Leverve XM.

Crit Care Med. 2008 Feb;36(2):637-8. doi: 10.1097/CCM.0B013E31816296AD. No abstract available.

PMID:
18216624
12.

Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity.

Taleux N, De Potter I, Deransart C, Lacraz G, Favier R, Leverve XM, Hue L, Guigas B.

Int J Obes (Lond). 2008 Apr;32(4):639-47. Epub 2007 Dec 4.

PMID:
18059408
13.

The flavonoid silibinin decreases glucose-6-phosphate hydrolysis in perfused rat hepatocytes by an inhibitory effect on glucose-6-phosphatase.

Guigas B, Naboulsi R, Villanueva GR, Taleux N, Lopez-Novoa JM, Leverve XM, El-Mir MY.

Cell Physiol Biochem. 2007;20(6):925-34. Erratum in: Cell Physiol Biochem. 2008;21(5-6):500.

14.

Mitochondrial function and substrate availability.

Leverve XM.

Crit Care Med. 2007 Sep;35(9 Suppl):S454-60. Review.

PMID:
17713393
15.

Intradialytic parenteral nutrition does not improve survival in malnourished hemodialysis patients: a 2-year multicenter, prospective, randomized study.

Cano NJ, Fouque D, Roth H, Aparicio M, Azar R, Canaud B, Chauveau P, Combe C, Laville M, Leverve XM; French Study Group for Nutrition in Dialysis.

J Am Soc Nephrol. 2007 Sep;18(9):2583-91. Epub 2007 Jul 26.

16.

Cardioprotective effect of spontaneous activity.

Peltier S, Novel-Chate V, Malaisse WJ, Molnar A, Leverve XM, Favier R.

Int J Sports Med. 2007 Dec;28(12):987-93. Epub 2007 May 29.

PMID:
17534785
17.

Nutritional management in acute illness and acute kidney insufficiency.

Leverve XM, Cano NJ.

Contrib Nephrol. 2007;156:112-8. Review.

PMID:
17464120
18.

The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock.

Albuszies G, Vogt J, Wachter U, Thiemermann C, Leverve XM, Weber S, Georgieff M, Radermacher P, Barth E.

Intensive Care Med. 2007 Jun;33(6):1094-101. Epub 2007 Apr 26.

PMID:
17458540
19.

Effects of a cantaloupe melon extract/wheat gliadin biopolymer during aortic cross-clamping.

Kick J, Hauser B, Bracht H, Albicini M, Oter S, Simon F, Ehrmann U, Garrel C, Sträter J, Brückner UB, Leverve XM, Schelzig H, Speit G, Radermacher P, Muth CM.

Intensive Care Med. 2007 Apr;33(4):694-702. Epub 2007 Jan 20.

PMID:
17237934
20.

Acute in vivo administration of a fish oil-containing emulsion improves post-ischemic cardiac function in n-3-depleted rats.

Peltier S, Malaisse WJ, Portois L, Demaison L, Novel-Chate V, Chardigny JM, Sebedio JL, Carpentier YA, Leverve XM.

Int J Mol Med. 2006 Oct;18(4):741-9.

PMID:
16964431
21.

The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin.

Batandier C, Guigas B, Detaille D, El-Mir MY, Fontaine E, Rigoulet M, Leverve XM.

J Bioenerg Biomembr. 2006 Feb;38(1):33-42.

PMID:
16732470
22.

Intradialytic parenteral nutrition: comparison of olive oil versus soybean oil-based lipid emulsions.

Cano NJ, Saingra Y, Dupuy AM, Lorec-Penet AM, Portugal H, Lairon D, Cristol JP, Come A, Le Brun A, Atlan P, Leverve XM.

Br J Nutr. 2006 Jan;95(1):152-9.

PMID:
16441928
23.

Application of branched-chain amino acids in human pathological states: renal failure.

Cano NJ, Fouque D, Leverve XM.

J Nutr. 2006 Jan;136(1 Suppl):299S-307S. doi: 10.1093/jn/136.1.299S. Review.

PMID:
16365103
24.

Lactate in the intensive care unit: pyromaniac, sentinel or fireman?

Leverve XM.

Crit Care. 2005;9(6):622-3. Epub 2005 Nov 25.

25.

Effect of exogenous adenosine and monensin on glycolytic flux in isolated perfused normoxic rat hearts: role of pyruvate kinase.

Peltier S, Burelle Y, Novel-Chate V, Demaison L, Verdys M, Saks V, Keriel C, Leverve XM.

Mol Cell Biochem. 2005 Sep;277(1-2):55-61.

PMID:
16132715
26.

Polyunsaturated fatty acid deficiency reverses effects of alcohol on mitochondrial energy metabolism.

Piquet MA, Roulet M, Nogueira V, Filippi C, Sibille B, Hourmand-Ollivier I, Pilet M, Rouleau V, Leverve XM.

J Hepatol. 2004 Nov;41(5):721-9.

PMID:
15519643
27.

Effect of chronic renal failure with metabolic acidosis on alanine metabolism in isolated liver cells.

Cano N, Sturm JM, Meijer AJ, El-Mir MY, Novaretti R, Reynier JP, Leverve XM.

Clin Nutr. 2004 Jun;23(3):317-24.

PMID:
15158294
28.

HMR1402, a potassium ATP channel blocker during hyperdynamic porcine endotoxemia: effects on hepato-splanchnic oxygen exchange and metabolism.

Asfar P, Iványi Z, Bracht H, Hauser B, Pittner A, Vassilev D, Nalos M, Leverve XM, Brückner UB, Radermacher P, Fröba G.

Intensive Care Med. 2004 May;30(5):957-64. Epub 2004 Mar 26.

PMID:
15045166
29.

Mitochondrial metabolism and type-2 diabetes: a specific target of metformin.

Leverve XM, Guigas B, Detaille D, Batandier C, Koceir EA, Chauvin C, Fontaine E, Wiernsperger NF.

Diabetes Metab. 2003 Sep;29(4 Pt 2):6S88-94. Review.

PMID:
14502105
30.

Effect of cardiopulmonary bypass on lactate metabolism.

Mustafa I, Roth H, Hanafiah A, Hakim T, Anwar M, Siregar E, Leverve XM.

Intensive Care Med. 2003 Aug;29(8):1279-85. Epub 2003 Jul 5.

PMID:
12845428
31.

Adenosine triphosphate-magnesium chloride: relevance for intensive care.

Nalos M, Asfar P, Ichai C, Radermacher P, Leverve XM, Fröba G.

Intensive Care Med. 2003 Jan;29(1):10-8. Epub 2002 Nov 2. Review.

PMID:
12528016
32.

How valid is the concept of antioxidants and cell injury?

Leverve XM, Batandier C, Fontaine E.

Nestle Nutr Workshop Ser Clin Perform Programme. 2002;7:67-81; discussion 81-5. Review. No abstract available.

PMID:
12481695
34.

Lactate: A key metabolite in the intercellular metabolic interplay.

Leverve XM, Mustafa I.

Crit Care. 2002 Aug;6(4):284-5. Epub 2002 Jul 8. No abstract available.

35.

Determination of mitochondrial reactive oxygen species: methodological aspects.

Batandier C, Fontaine E, Kériel C, Leverve XM.

J Cell Mol Med. 2002 Apr-Jun;6(2):175-87. Review.

36.

Adenosine triphosphate-magnesium dichloride during hyperdynamic porcine endotoxemia: effects on hepatosplanchnic oxygen exchange and metabolism.

Asfar P, Nalos M, Pittner A, Theisen M, Ichai C, Ploner F, Georgieff M, Ince C, Brückner UB, Leverve XM, Radermacher P, Froeba G.

Crit Care Med. 2002 Aug;30(8):1826-33.

PMID:
12163801
37.

Malnutrition in hemodialysis diabetic patients: evaluation and prognostic influence.

Cano NJ, Roth H, Aparicio M, Azar R, Canaud B, Chauveau P, Combe C, Fouque D, Laville M, Leverve XM; French Study Group for Nutrition in Dialysis (FSG-ND).

Kidney Int. 2002 Aug;62(2):593-601.

38.

Thyroid status is a key regulator of both flux and efficiency of oxidative phosphorylation in rat hepatocytes.

Nogueira V, Walter L, Avéret N, Fontaine E, Rigoulet M, Leverve XM.

J Bioenerg Biomembr. 2002 Feb;34(1):55-66.

PMID:
11860181
39.

Role of substrates in the regulation of mitochondrial function in situ.

Leverve XM, Fontaine E.

IUBMB Life. 2001 Sep-Nov;52(3-5):221-9. Review.

40.

Mitochondrial respiratory chain adjustment to cellular energy demand.

Nogueira V, Rigoulet M, Piquet MA, Devin A, Fontaine E, Leverve XM.

J Biol Chem. 2001 Dec 7;276(49):46104-10. Epub 2001 Sep 28.

41.

Mitochondrial adaptation to in vivo polyunsaturated fatty acid deficiency: increase in phosphorylation efficiency.

Nogueira V, Piquet MA, Devin A, Fiore C, Fontaine E, Brandolin G, Rigoulet M, Leverve XM.

J Bioenerg Biomembr. 2001 Feb;33(1):53-61.

PMID:
11460926
42.

Glucose 6-phosphate hydrolysis is activated by glucagon in a low temperature-sensitive manner.

Ichai C, Guignot L, El-Mir MY, Nogueira V, Guigas B, Chauvin C, Fontaine E, Mithieux G, Leverve XM.

J Biol Chem. 2001 Jul 27;276(30):28126-33. Epub 2001 May 22.

43.

Inter-organ substrate exchanges in the critically ill.

Leverve XM.

Curr Opin Clin Nutr Metab Care. 2001 Mar;4(2):137-42. Review.

PMID:
11224659
44.

Exogenous Mg-ATP induces a large inhibition of pyruvate kinase in intact rat hepatocytes.

Ichai C, El-Mir MY, Nogueira V, Piquet MA, Chauvin C, Fontaine E, Leverve XM.

J Biol Chem. 2001 Mar 2;276(9):6398-403. Epub 2000 Dec 4.

45.

Chronic ethanol ingestion increases efficiency of oxidative phosphorylation in rat liver mitochondria.

Piquet MA, Nogueira V, Devin A, Sibille B, Filippi C, Fontaine E, Roulet M, Rigoulet M, Leverve XM.

FEBS Lett. 2000 Feb 25;468(2-3):239-42.

46.

From tissue perfusion to metabolic marker: assessing organ competition and co-operation in critically ill patients?

Leverve XM.

Intensive Care Med. 1999 Sep;25(9):890-2. Review. No abstract available.

PMID:
10501739
47.

Energy metabolism in critically ill patients: lactate is a major oxidizable substrate.

Leverve XM.

Curr Opin Clin Nutr Metab Care. 1999 Mar;2(2):165-9. Review.

PMID:
10453349
48.

Lactic acidosis. A new insight?

Leverve XM.

Minerva Anestesiol. 1999 May;65(5):205-9. Review.

PMID:
10389393
49.

In vivo hypoxic exposure impairs metabolic adaptations to a 48 hour fast in rats.

Pison CM, Chauvin C, Perrault H, Schwebel C, Lafond JL, Boujet C, Leverve XM.

Eur Respir J. 1998 Sep;12(3):658-65.

50.

Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats.

Leclercq P, Filippi C, Sibille B, Hamant S, Keriel C, Leverve XM.

Biochem J. 1997 Jul 15;325 ( Pt 2):519-25.

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