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Items: 1 to 50 of 203

1.

Migratory Dendritic Cells, Group 1 Innate Lymphoid Cells, and Inflammatory Monocytes Collaborate to Recruit NK Cells to the Virus-Infected Lymph Node.

Wong E, Xu RH, Rubio D, Lev A, Stotesbury C, Fang M, Sigal LJ.

Cell Rep. 2018 Jul 3;24(1):142-154. doi: 10.1016/j.celrep.2018.06.004.

2.

Co-appearance of OPV and BCG vaccine-derived complications in two infants with severe combined immunodeficiency.

Heiman S, Weil M, Shulman LM, Simon AJ, Lev A, Somech R, Stauber T.

Immunol Res. 2018 Jun;66(3):437-443. doi: 10.1007/s12026-018-9007-6.

PMID:
29804197
3.

Comparative analysis of Klebsiella pneumoniae strains isolated in 2012-2016 that differ by antibiotic resistance genes and virulence genes profiles.

Lev AI, Astashkin EI, Kislichkina AA, Solovieva EV, Kombarova TI, Korobova OV, Ershova ON, Alexandrova IA, Malikov VE, Bogun AG, Borzilov AI, Volozhantsev NV, Svetoch EA, Fursova NK.

Pathog Glob Health. 2018 May;112(3):142-151. doi: 10.1080/20477724.2018.1460949. Epub 2018 Apr 30.

PMID:
29708041
4.

ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer.

Lev A, Lulla AR, Ross BC, Ralff MD, Makhov PB, Dicker DT, El-Deiry WS.

Mol Cancer Res. 2018 May;16(5):754-766. doi: 10.1158/1541-7786.MCR-17-0614. Epub 2018 Mar 27.

PMID:
29588330
5.

First Year of Israeli Newborn Screening for Severe Combined Immunodeficiency-Clinical Achievements and Insights.

Rechavi E, Lev A, Simon AJ, Stauber T, Daas S, Saraf-Levy T, Broides A, Nahum A, Marcus N, Hanna S, Stepensky P, Toker O, Dalal I, Etzioni A, Almashanu S, Somech R.

Front Immunol. 2017 Nov 6;8:1448. doi: 10.3389/fimmu.2017.01448. eCollection 2017.

6.

Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP.

Lev A, Lulla AR, Wagner J, Ralff MD, Kiehl JB, Zhou Y, Benes CH, Prabhu VV, Oster W, Astsaturov I, Dicker DT, El-Deiry WS.

Oncotarget. 2017 Sep 12;8(47):81776-81793. doi: 10.18632/oncotarget.20819. eCollection 2017 Oct 10.

7.

Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B.

Somech R, Lev A, Lee YN, Simon AJ, Barel O, Schiby G, Avivi C, Barshack I, Rhodes M, Yin J, Wang M, Yang Y, Rhodes J, Marcus N, Garty BZ, Stein J, Amariglio N, Rechavi G, Wiest DL, Zhang Y.

J Immunol. 2017 Dec 15;199(12):4036-4045. doi: 10.4049/jimmunol.1700460. Epub 2017 Nov 10.

PMID:
29127144
8.

miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells.

Lulla AR, Slifker MJ, Zhou Y, Lev A, Einarson MB, Dicker DT, El-Deiry WS.

Cancer Res. 2017 Dec 15;77(24):6902-6913. doi: 10.1158/0008-5472.CAN-17-1767. Epub 2017 Oct 23.

PMID:
29061672
9.

Genome Sequences of Two NDM-1 Metallo-β-Lactamase-Producing Multidrug-Resistant Strains of Klebsiella pneumoniae with a High Degree of Similarity, One of Which Contains Prophage.

Volozhantsev NV, Kislichkina AA, Lev AI, Mukhina TN, Bogun AA, Ershova ON, Alexandrova IA, Fursova NK.

Genome Announc. 2017 Oct 19;5(42). pii: e01173-17. doi: 10.1128/genomeA.01173-17.

10.

Comparative genome analysis of novel Podoviruses lytic for hypermucoviscous Klebsiella pneumoniae of K1, K2, and K57 capsular types.

Solovieva EV, Myakinina VP, Kislichkina AA, Krasilnikova VM, Verevkin VV, Mochalov VV, Lev AI, Fursova NK, Volozhantsev NV.

Virus Res. 2018 Jan 2;243:10-18. doi: 10.1016/j.virusres.2017.09.026. Epub 2017 Oct 5.

PMID:
28988127
11.

Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures.

Finnberg NK, Gokare P, Lev A, Grivennikov SI, MacFarlane AW 4th, Campbell KS, Winters RM, Kaputa K, Farma JM, Abbas AE, Grasso L, Nicolaides NC, El-Deiry WS.

Oncotarget. 2017 Aug 5;8(40):66747-66757. doi: 10.18632/oncotarget.19965. eCollection 2017 Sep 15.

12.

Preclinical rationale for combination of crizotinib with mitomycin C for the treatment of advanced colorectal cancer.

Lev A, Deihimi S, Shagisultanova E, Xiu J, Lulla AR, Dicker DT, El-Deiry WS.

Cancer Biol Ther. 2017 Sep 2;18(9):694-704. doi: 10.1080/15384047.2017.1364323. Epub 2017 Sep 8.

PMID:
28886275
13.

Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.

Prabhu VV, Lulla AR, Madhukar NS, Ralff MD, Zhao D, Kline CLB, Van den Heuvel APJ, Lev A, Garnett MJ, McDermott U, Benes CH, Batchelor TT, Chi AS, Elemento O, Allen JE, El-Deiry WS.

PLoS One. 2017 Aug 2;12(8):e0180541. doi: 10.1371/journal.pone.0180541. eCollection 2017.

14.

BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.

Deihimi S, Lev A, Slifker M, Shagisultanova E, Xu Q, Jung K, Vijayvergia N, Ross EA, Xiu J, Swensen J, Gatalica Z, Andrake M, Dunbrack RL, El-Deiry WS.

Oncotarget. 2017 Jun 20;8(25):39945-39962. doi: 10.18632/oncotarget.18098.

15.

Quantification of specific T and B cells immunological markers in children with chronic and transient ITP.

Levy-Mendelovich S, Lev A, Aviner S, Rosenberg N, Kaplinsky C, Sharon N, Miskin H, Dvir A, Kenet G, Schushan IE, Somech R.

Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26646. Epub 2017 May 22.

PMID:
28544224
16.

T and B cell clonal expansion in Ras-associated lymphoproliferative disease (RALD) as revealed by next-generation sequencing.

Levy-Mendelovich S, Lev A, Rechavi E, Barel O, Golan H, Bielorai B, Neumann Y, Simon AJ, Somech R.

Clin Exp Immunol. 2017 Sep;189(3):310-317. doi: 10.1111/cei.12986. Epub 2017 Jun 5.

PMID:
28500641
17.

Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212.

Wagner J, Kline CL, Ralff MD, Lev A, Lulla A, Zhou L, Olson GL, Nallaganchu BR, Benes CH, Allen JE, Prabhu VV, Stogniew M, Oster W, El-Deiry WS.

Cell Cycle. 2017 Oct 2;16(19):1790-1799. doi: 10.1080/15384101.2017.1325046. Epub 2017 May 10.

18.

Identification of IS1R and IS10R elements inserted into ompk36 porin gene of two multidrug-resistant Klebsiella pneumoniae hospital strains.

Lev AI, Astashkin EI, Shaikhutdinova RZ, Platonov ME, Kartsev NN, Volozhantsev NV, Ershova ON, Svetoch EA, Fursova NK.

FEMS Microbiol Lett. 2017 May 1;364(10). doi: 10.1093/femsle/fnx072.

PMID:
28402509
19.

Genome sequencing and comparative analysis of three hypermucoviscous Klebsiella pneumoniae strains isolated in Russia.

Kislichkina AA, Lev AI, Komisarova EV, Fursova NK, Myakinina VP, Mukhina TN, Bogun AA, Volozhantsev NV.

Pathog Dis. 2017 Jun 1;75(4). doi: 10.1093/femspd/ftx024.

PMID:
28334288
20.

The clinical and laboratory spectrum of dedicator of cytokinesis 8 immunodeficiency syndrome in patients with a unique mutation.

Broides A, Mandola AB, Levy J, Yerushalmi B, Pinsk V, Eldan M, Shubinsky G, Hadad N, Levy R, Nahum A, Ben-Harosh M, Lev A, Simon A, Somech R.

Immunol Res. 2017 Jun;65(3):651-657. doi: 10.1007/s12026-016-8883-x.

PMID:
28070732
21.

Immunological effects of nilotinib prophylaxis after allogeneic stem cell transplantation in patients with advanced chronic myeloid leukemia or philadelphia chromosome-positive acute lymphoblastic leukemia.

Varda-Bloom N, Danylesko I, Shouval R, Eldror S, Lev A, Davidson J, Rosenthal E, Volchek Y, Shem-Tov N, Yerushalmi R, Shimoni A, Somech R, Nagler A.

Oncotarget. 2017 Jan 3;8(1):418-429. doi: 10.18632/oncotarget.13439.

22.

A Novel Mutation in a Critical Region for the Methyl Donor Binding in DNMT3B Causes Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome (ICF).

Rechavi E, Lev A, Eyal E, Barel O, Kol N, Barhom SF, Pode-Shakked B, Anikster Y, Somech R, Simon AJ.

J Clin Immunol. 2016 Nov;36(8):801-809. Epub 2016 Oct 12.

PMID:
27734333
23.

Discovery and clinical introduction of first-in-class imipridone ONC201.

Allen JE, Kline CL, Prabhu VV, Wagner J, Ishizawa J, Madhukar N, Lev A, Baumeister M, Zhou L, Lulla A, Stogniew M, Schalop L, Benes C, Kaufman HL, Pottorf RS, Nallaganchu BR, Olson GL, Al-Mulla F, Duvic M, Wu GS, Dicker DT, Talekar MK, Lim B, Elemento O, Oster W, Bertino J, Flaherty K, Wang ML, Borthakur G, Andreeff M, Stein M, El-Deiry WS.

Oncotarget. 2016 Nov 8;7(45):74380-74392. doi: 10.18632/oncotarget.11814. Review.

24.

G23D: Online tool for mapping and visualization of genomic variants on 3D protein structures.

Solomon O, Kunik V, Simon A, Kol N, Barel O, Lev A, Amariglio N, Somech R, Rechavi G, Eyal E.

BMC Genomics. 2016 Aug 26;17:681. doi: 10.1186/s12864-016-3028-0.

25.

Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects.

Simon AJ, Lev A, Zhang Y, Weiss B, Rylova A, Eyal E, Kol N, Barel O, Cesarkas K, Soudack M, Greenberg-Kushnir N, Rhodes M, Wiest DL, Schiby G, Barshack I, Katz S, Pras E, Poran H, Reznik-Wolf H, Ribakovsky E, Simon C, Hazou W, Sidi Y, Lahad A, Katzir H, Sagie S, Aqeilan HA, Glousker G, Amariglio N, Tzfati Y, Selig S, Rechavi G, Somech R.

J Exp Med. 2016 Jul 25;213(8):1429-40. doi: 10.1084/jem.20151618. Epub 2016 Jul 18.

26.

Combined immunodeficiency in a patient with mosaic monosomy 21.

Rechavi E, Levy-Mendelovich S, Stauber T, Shamash J, Reinstein S, Vernitsky H, Adam D, Simon AJ, Lev A, Raas-Rothschild A, Somech R.

Immunol Res. 2016 Aug;64(4):841-7. doi: 10.1007/s12026-016-8803-0.

PMID:
27216863
27.

Thymus Activity, Vitamin D, and Respiratory Infections in Adolescent Swimmers.

Mayan I, Somech R, Lev A, Cohen AH, Constantini NW, Dubnov-Raz G.

Isr Med Assoc J. 2015 Sep;17(9):571-5.

28.

Acousto-optical detection of hidden objects via speckle based imaging.

Lev A, Sfez B.

Opt Express. 2015 Oct 5;23(20):26460-71. doi: 10.1364/OE.23.026460.

PMID:
26480159
29.

Highlighting the problematic reliance on CD18 for diagnosing leukocyte adhesion deficiency type 1.

Levy-Mendelovich S, Rechavi E, Abuzaitoun O, Vernitsky H, Simon AJ, Lev A, Somech R.

Immunol Res. 2016 Apr;64(2):476-82. doi: 10.1007/s12026-015-8706-5.

PMID:
26434744
30.

Correlation between 'ACKR1/DARC null' polymorphism and benign neutropenia in Yemenite Jews.

Rappoport N, Simon AJ, Lev A, Yacobi M, Kaplinsky C, Weingarten M, Somech R, Amariglio N, Rechavi G.

Br J Haematol. 2015 Sep;170(6):892-5. doi: 10.1111/bjh.13345. Epub 2015 Mar 26. No abstract available.

PMID:
25817587
31.

The effect of different oral hygiene treatments on the occurrence of ventilator associated pneumonia (VAP) in ventilated patients.

Lev A, Aied AS, Arshed S.

J Infect Prev. 2015 Mar;16(2):76-81. doi: 10.1177/1757177414560252. Epub 2014 Dec 10.

32.

Timely and spatially regulated maturation of B and T cell repertoire during human fetal development.

Rechavi E, Lev A, Lee YN, Simon AJ, Yinon Y, Lipitz S, Amariglio N, Weisz B, Notarangelo LD, Somech R.

Sci Transl Med. 2015 Feb 25;7(276):276ra25. doi: 10.1126/scitranslmed.aaa0072.

PMID:
25717098
33.

Thymic and bone marrow output in individuals with 22q11.2 deletion syndrome.

Dar N, Gothelf D, Korn D, Frisch A, Weizman A, Michaelovsky E, Carmel M, Yeshayahu Y, Dubnov-Raz G, Pessach IM, Simon AJ, Lev A, Somech R.

Pediatr Res. 2015 Apr;77(4):579-85. doi: 10.1038/pr.2015.14. Epub 2015 Jan 12.

PMID:
25580739
34.

Insight into normal thymic activity by assessment of peripheral blood samples.

Machnes-Maayan D, Lev A, Katz U, Mishali D, Vardi A, Simon AJ, Somech R.

Immunol Res. 2015 Mar;61(3):198-205. doi: 10.1007/s12026-014-8558-4.

PMID:
25294167
35.

Testicular failure in a patient with G6PC3 deficiency.

Yeshayahu Y, Asaf R, Dubnov-Raz G, Schiby G, Simon AJ, Lev A, Somech R.

Pediatr Res. 2014 Aug;76(2):197-201. doi: 10.1038/pr.2014.64. Epub 2014 May 5.

PMID:
24796372
36.

Disturbed B and T cell homeostasis and neogenesis in patients with ataxia telangiectasia.

Kraus M, Lev A, Simon AJ, Levran I, Nissenkorn A, Levi YB, Berkun Y, Efrati O, Amariglio N, Rechavi G, Somech R.

J Clin Immunol. 2014 Jul;34(5):561-72. doi: 10.1007/s10875-014-0044-1. Epub 2014 May 1.

PMID:
24789685
37.

Co-existence of clonal expanded autologous and transplacental-acquired maternal T cells in recombination activating gene-deficient severe combined immunodeficiency.

Lev A, Simon AJ, Ben-Ari J, Takagi D, Stauber T, Trakhtenbrot L, Rosenthal E, Rechavi G, Amariglio N, Somech R.

Clin Exp Immunol. 2014 Jun;176(3):380-6. doi: 10.1111/cei.12273.

38.

Novel SMARCAL1 bi-allelic mutations associated with a chromosomal breakage phenotype in a severe SIOD patient.

Simon AJ, Lev A, Jeison M, Borochowitz ZU, Korn D, Lerenthal Y, Somech R.

J Clin Immunol. 2014 Jan;34(1):76-83. doi: 10.1007/s10875-013-9957-3. Epub 2013 Nov 7.

PMID:
24197801
39.

Newborn screening for severe T and B cell immunodeficiency in Israel: a pilot study.

Somech R, Lev A, Simon AJ, Korn D, Garty BZ, Amariglio N, Rechavi G, Almashanu S, Zlotogora J, Etzioni A.

Isr Med Assoc J. 2013 Aug;15(8):404-9.

40.

A congenital neutrophil defect syndrome associated with mutations in VPS45.

Vilboux T, Lev A, Malicdan MC, Simon AJ, Järvinen P, Racek T, Puchalka J, Sood R, Carrington B, Bishop K, Mullikin J, Huizing M, Garty BZ, Eyal E, Wolach B, Gavrieli R, Toren A, Soudack M, Atawneh OM, Babushkin T, Schiby G, Cullinane A, Avivi C, Polak-Charcon S, Barshack I, Amariglio N, Rechavi G, van der Werff ten Bosch J, Anikster Y, Klein C, Gahl WA, Somech R.

N Engl J Med. 2013 Jul 4;369(1):54-65. doi: 10.1056/NEJMoa1301296. Epub 2013 Jun 5.

41.

Memory CD8⁺ T cells can outsource IFN-γ production but not cytolytic killing for antiviral protection.

Remakus S, Rubio D, Lev A, Ma X, Fang M, Xu RH, Sigal LJ.

Cell Host Microbe. 2013 May 15;13(5):546-557. doi: 10.1016/j.chom.2013.04.004.

42.

Severe eosinophilia in children: a diagnostic dilemma.

Amshalom A, Lev A, Trakhtenbrot L, Golan H, Weiss B, Amariglio N, Rechavi G, Somech R.

J Pediatr Hematol Oncol. 2013 May;35(4):303-6. doi: 10.1097/MPH.0b013e318290bf0b.

PMID:
23612381
43.

Getting in front and behind the enemy lines to counter virus infection.

Lev A, Sigal L.

Cell Host Microbe. 2013 Feb 13;13(2):121-2. doi: 10.1016/j.chom.2013.01.013.

44.

Purine nucleoside phosphorylase deficiency presenting as severe combined immune deficiency.

Somech R, Lev A, Grisaru-Soen G, Shiran SI, Simon AJ, Grunebaum E.

Immunol Res. 2013 May;56(1):150-4. doi: 10.1007/s12026-012-8380-9.

PMID:
23371835
45.

Characterizing T cells in SCID patients presenting with reactive or residual T lymphocytes.

Lev A, Simon AJ, Trakhtenbrot L, Goldstein I, Nagar M, Stepensky P, Rechavi G, Amariglio N, Somech R.

Clin Dev Immunol. 2012;2012:261470. doi: 10.1155/2012/261470. Epub 2012 Nov 20.

46.

Thymic function in MHC class II-deficient patients.

Lev A, Simon AJ, Broides A, Levi J, Garty BZ, Rosenthal E, Amariglio N, Rechavi G, Somech R.

J Allergy Clin Immunol. 2013 Mar;131(3):831-9. doi: 10.1016/j.jaci.2012.10.040. Epub 2012 Dec 8.

PMID:
23228244
47.

Fully automated derivation of coronary artery calcium scores and cardiovascular risk assessment from contrast medium-enhanced coronary CT angiography studies.

Ebersberger U, Eilot D, Goldenberg R, Lev A, Spears JR, Rowe GW, Gallagher NY, Halligan WT, Blanke P, Makowski MR, Krazinski AW, Silverman JR, Bamberg F, Leber AW, Hoffmann E, Schoepf UJ.

Eur Radiol. 2013 Mar;23(3):650-7. doi: 10.1007/s00330-012-2652-6. Epub 2012 Sep 16.

PMID:
22983281
48.

T- and B-cell defects in a novel purine nucleoside phosphorylase mutation.

Somech R, Lev A, Simon AJ, Hanna S, Etzioni A.

J Allergy Clin Immunol. 2012 Aug;130(2):539-42. doi: 10.1016/j.jaci.2012.03.038. Epub 2012 May 10. No abstract available.

PMID:
22578971
49.

Prolonged propriospinal myoclonus following spinal anesthesia for cesarean section: case report and literature review.

Lev A, Korn-Lubezki I, Steiner-Birmanns B, Samueloff A, Gozal Y, Ioscovich A.

Arch Gynecol Obstet. 2012 Jul;286(1):271-2. doi: 10.1007/s00404-012-2246-1. Review. No abstract available.

PMID:
22302138
50.

The kinetics of early T and B cell immune recovery after bone marrow transplantation in RAG-2-deficient SCID patients.

Lev A, Simon AJ, Bareket M, Bielorai B, Hutt D, Amariglio N, Rechavi G, Somech R.

PLoS One. 2012;7(1):e30494. doi: 10.1371/journal.pone.0030494. Epub 2012 Jan 25.

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