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Items: 9

1.

Peptide-β-lactam Inhibitors of Dengue and West Nile Virus NS2B-NS3 Protease Display Two Distinct Binding Modes.

Dražić T, Kopf S, Corridan J, Leuthold MM, Bertoša B, Klein CD.

J Med Chem. 2020 Jan 9;63(1):140-156. doi: 10.1021/acs.jmedchem.9b00759. Epub 2019 Dec 24.

PMID:
31804823
2.

Prodrug Activation by a Viral Protease: Evaluating Combretastatin Peptide Hybrids To Selectively Target Infected Cells.

Richter M, Leuthold MM, Graf D, Bartenschlager R, Klein CD.

ACS Med Chem Lett. 2019 Jul 18;10(8):1115-1121. doi: 10.1021/acsmedchemlett.9b00058. eCollection 2019 Aug 8.

PMID:
31413794
3.

De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease.

Nitsche C, Passioura T, Varava P, Mahawaththa MC, Leuthold MM, Klein CD, Suga H, Otting G.

ACS Med Chem Lett. 2019 Jan 4;10(2):168-174. doi: 10.1021/acsmedchemlett.8b00535. eCollection 2019 Feb 14.

4.

Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens.

Singh BK, Leuthold MM, Hansman GS.

mSphere. 2016 Mar 30;1(2). pii: e00049-16. doi: 10.1128/mSphere.00049-16. eCollection 2016 Mar-Apr.

5.

Production of Human Norovirus Protruding Domains in E. coli for X-ray Crystallography.

Leuthold MM, Koromyslova AD, Singh BK, Hansman GS.

J Vis Exp. 2016 Apr 19;(110). doi: 10.3791/53845.

6.

The sweet quartet: Binding of fucose to the norovirus capsid.

Koromyslova AD, Leuthold MM, Bowler MW, Hansman GS.

Virology. 2015 Sep;483:203-8. doi: 10.1016/j.virol.2015.04.006. Epub 2015 May 15.

7.

Structural analysis of a rabbit hemorrhagic disease virus binding to histo-blood group antigens.

Leuthold MM, Dalton KP, Hansman GS.

J Virol. 2015 Feb;89(4):2378-87. doi: 10.1128/JVI.02832-14. Epub 2014 Dec 10.

8.

Structural analysis of a feline norovirus protruding domain.

Singh BK, Glatt S, Ferrer JL, Koromyslova AD, Leuthold MM, Dunder J, Hansman GS.

Virology. 2015 Jan 1;474:181-5. doi: 10.1016/j.virol.2014.10.028. Epub 2014 Nov 19.

9.

Human noroviruses' fondness for histo-blood group antigens.

Singh BK, Leuthold MM, Hansman GS.

J Virol. 2015 Feb;89(4):2024-40. doi: 10.1128/JVI.02968-14. Epub 2014 Nov 26.

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