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Items: 17

1.

Xbp1s-Negative Tumor B Cells and Pre-Plasmablasts Mediate Therapeutic Proteasome Inhibitor Resistance in Multiple Myeloma.

Leung-Hagesteijn C, Erdmann N, Cheung G, Keats JJ, Stewart AK, Reece DE, Chung KC, Tiedemann RE.

Cancer Cell. 2015 Oct 12;28(4):541-542. doi: 10.1016/j.ccell.2015.09.010. Epub 2015 Oct 12. No abstract available.

2.

Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma.

Leung-Hagesteijn C, Erdmann N, Cheung G, Keats JJ, Stewart AK, Reece DE, Chung KC, Tiedemann RE.

Cancer Cell. 2013 Sep 9;24(3):289-304. doi: 10.1016/j.ccr.2013.08.009. Erratum in: Cancer Cell. 2015 Oct 12;28(4):541-2.

3.

Molecular target characterization and antimyeloma activity of the novel, insulin-like growth factor 1 receptor inhibitor, GTx-134.

Liang SB, Yang XZ, Trieu Y, Li Z, Zive J, Leung-Hagesteijn C, Wei E, Zozulya S, Coss CC, Dalton JT, Fantus IG, Trudel S.

Clin Cancer Res. 2011 Jul 15;17(14):4693-704. doi: 10.1158/1078-0432.CCR-10-3097. Epub 2011 Jun 1.

4.

Single-agent lenalidomide in the treatment of previously untreated chronic lymphocytic leukemia.

Chen CI, Bergsagel PL, Paul H, Xu W, Lau A, Dave N, Kukreti V, Wei E, Leung-Hagesteijn C, Li ZH, Brandwein J, Pantoja M, Johnston J, Gibson S, Hernandez T, Spaner D, Trudel S.

J Clin Oncol. 2011 Mar 20;29(9):1175-81. doi: 10.1200/JCO.2010.29.8133. Epub 2010 Dec 28.

5.

Integrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesis.

Leung-Hagesteijn C, Hu MC, Mahendra AS, Hartwig S, Klamut HJ, Rosenblum ND, Hannigan GE.

Mol Cell Biol. 2005 May;25(9):3648-57.

6.

Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer.

Mongroo PS, Johnstone CN, Naruszewicz I, Leung-Hagesteijn C, Sung RK, Carnio L, Rustgi AK, Hannigan GE.

Oncogene. 2004 Nov 25;23(55):8959-70.

PMID:
15467740
7.

ILKAP regulates ILK signaling and inhibits anchorage-independent growth.

Kumar AS, Naruszewicz I, Wang P, Leung-Hagesteijn C, Hannigan GE.

Oncogene. 2004 Apr 22;23(19):3454-61.

PMID:
14990992
8.

Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.

Leung-Hagesteijn C, Mahendra A, Naruszewicz I, Hannigan GE.

EMBO J. 2001 May 1;20(9):2160-70.

9.

Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways.

Novak A, Hsu SC, Leung-Hagesteijn C, Radeva G, Papkoff J, Montesano R, Roskelley C, Grosschedl R, Dedhar S.

Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4374-9.

10.

Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity.

Wu C, Keightley SY, Leung-Hagesteijn C, Radeva G, Coppolino M, Goicoechea S, McDonald JA, Dedhar S.

J Biol Chem. 1998 Jan 2;273(1):528-36.

11.

Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression.

Radeva G, Petrocelli T, Behrend E, Leung-Hagesteijn C, Filmus J, Slingerland J, Dedhar S.

J Biol Chem. 1997 May 23;272(21):13937-44.

12.

Modulation of the retinoic acid and retinoid X receptor signaling pathways in P19 embryonal carcinoma cells by calreticulin.

Shago M, Flock G, Leung Hagesteijn CY, Woodside M, Grinstein S, Giguère V, Dedhar S.

Exp Cell Res. 1997 Jan 10;230(1):50-60.

PMID:
9013706
13.

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase.

Hannigan GE, Leung-Hagesteijn C, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, Bell JC, Dedhar S.

Nature. 1996 Jan 4;379(6560):91-6.

PMID:
8538749
14.

Constitutive expression of calreticulin in osteoblasts inhibits mineralization.

St-Arnaud R, Prud'homme J, Leung-Hagesteijn C, Dedhar S.

J Cell Biol. 1995 Dec;131(5):1351-9.

15.

Inducible interaction of integrin alpha 2 beta 1 with calreticulin. Dependence on the activation state of the integrin.

Coppolino M, Leung-Hagesteijn C, Dedhar S, Wilkins J.

J Biol Chem. 1995 Sep 29;270(39):23132-8.

16.
17.

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans.

Leung-Hagesteijn C, Spence AM, Stern BD, Zhou Y, Su MW, Hedgecock EM, Culotti JG.

Cell. 1992 Oct 16;71(2):289-99.

PMID:
1384987

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