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Items: 1 to 50 of 54


Acupuncture and related interventions for carpal tunnel syndrome: systematic review.

Wu IX, Lam VC, Ho RS, Cheung WK, Sit RW, Chou LW, Zhang Y, Leung TH, Chung VC.

Clin Rehabil. 2019 Sep 26:269215519877511. doi: 10.1177/0269215519877511. [Epub ahead of print]


Prioritizing Chinese Medicine Clinical Research Questions in Cancer Palliative Care: International Delphi Survey.

Wong CHL, Wu IXY, Balneaves LG, Lo RSK, Witt CM, Wu JCY, Leung TH, Chung VCH.

J Pain Symptom Manage. 2019 Aug 9. pii: S0885-3924(19)30443-9. doi: 10.1016/j.jpainsymman.2019.08.002. [Epub ahead of print]


Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells.

Chen RR, Yung MMH, Xuan Y, Zhan S, Leung LL, Liang RR, Leung THY, Yang H, Xu D, Sharma R, Chan KKL, Ngu SF, Ngan HYS, Chan DW.

Commun Biol. 2019 Jul 31;2:281. doi: 10.1038/s42003-019-0508-1. eCollection 2019.


CD71+ Population Enriched by HPV-E6 Protein Promotes Cancer Aggressiveness and Radioresistance in Cervical Cancer Cells.

Leung TH, Tang HW, Siu MK, Chan DW, Chan KK, Cheung AN, Ngan HY.

Mol Cancer Res. 2019 Sep;17(9):1867-1880. doi: 10.1158/1541-7786.MCR-19-0068. Epub 2019 Jun 24.


Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades.

Siu MKY, Jiang YX, Wang JJ, Leung THY, Han CY, Tsang BK, Cheung ANY, Ngan HYS, Chan KKL.

Cancers (Basel). 2019 Jun 12;11(6). pii: E813. doi: 10.3390/cancers11060813.


Research Techniques Made Simple: Parabiosis to Elucidate Humoral Factors in Skin Biology.

Spencer CA, Leung TH.

J Invest Dermatol. 2019 Jun;139(6):1208-1213.e1. doi: 10.1016/j.jid.2019.03.1134.


Resolution of cutaneous sarcoidosis after Janus kinase inhibitor therapy for concomitant polycythemia vera.

Wei JJ, Kallenbach LR, Kreider M, Leung TH, Rosenbach M.

JAAD Case Rep. 2019 Apr 5;5(4):360-361. doi: 10.1016/j.jdcr.2019.02.006. eCollection 2019 Apr. No abstract available.


Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration.

Nishiguchi MA, Spencer CA, Leung DH, Leung TH.

Cell Rep. 2018 Dec 26;25(13):3898. doi: 10.1016/j.celrep.2018.12.056. No abstract available.


Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration.

Nishiguchi MA, Spencer CA, Leung DH, Leung TH.

Cell Rep. 2018 Sep 25;24(13):3383-3392.e5. doi: 10.1016/j.celrep.2018.08.054. Erratum in: Cell Rep. 2018 Dec 26;25(13):3898.


Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer.

Chan KKL, Siu MKY, Jiang YX, Wang JJ, Leung THY, Ngan HYS.

Cancer Cell Int. 2018 May 1;18:65. doi: 10.1186/s12935-018-0559-2. eCollection 2018.


Novel selective medium for the isolation of corynebacterium kroppenstedtii from heavily colonised clinical specimens.

Wong SCY, Poon RWS, Foo CH, Ngan AHY, Tse H, Lam VCM, Leung THY, Wong CP, Cheng VCC, Chen JHK, Yuen KY.

J Clin Pathol. 2018 Sep;71(9):781-786. doi: 10.1136/jclinpath-2017-204834. Epub 2018 Mar 28.


GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade.

Yung MM, Tang HW, Cai PC, Leung TH, Ngu SF, Chan KK, Xu D, Yang H, Ngan HY, Chan DW.

Theranostics. 2018 Feb 2;8(5):1270-1285. doi: 10.7150/thno.22536. eCollection 2018.


Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways.

Chen K, Liu MX, Mak CS, Yung MM, Leung TH, Xu D, Ngu SF, Chan KK, Yang H, Ngan HY, Chan DW.

Theranostics. 2018 Jan 1;8(2):423-436. doi: 10.7150/thno.22377. eCollection 2018.


Evaluation of the molecular Xpert Xpress Flu/RSV assay vs. Alere i Influenza A & B assay for rapid detection of influenza viruses.

Chen JH, Lam HY, Yip CC, Cheng VC, Chan JF, Leung TH, Sridhar S, Chan KH, Tang BS, Yuen KY.

Diagn Microbiol Infect Dis. 2018 Mar;90(3):177-180. doi: 10.1016/j.diagmicrobio.2017.11.010. Epub 2017 Nov 24.


Mean-Field Scaling of the Superfluid to Mott Insulator Transition in a 2D Optical Superlattice.

Thomas CK, Barter TH, Leung TH, Okano M, Jo GB, Guzman J, Kimchi I, Vishwanath A, Stamper-Kurn DM.

Phys Rev Lett. 2017 Sep 8;119(10):100402. doi: 10.1103/PhysRevLett.119.100402. Epub 2017 Sep 6.


Human papillomavirus E6 protein enriches the CD55(+) population in cervical cancer cells, promoting radioresistance and cancer aggressiveness.

Leung TH, Tang HW, Siu MK, Chan DW, Chan KK, Cheung AN, Ngan HY.

J Pathol. 2018 Feb;244(2):151-163. doi: 10.1002/path.4991. Epub 2017 Dec 19.


Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis.

Chan KKL, Siu MKY, Jiang YX, Wang JJ, Wang Y, Leung THY, Liu SS, Cheung ANY, Ngan HYS.

BMC Cancer. 2017 Aug 31;17(1):606. doi: 10.1186/s12885-017-3601-1.


Development of integrative medicine in Hong Kong, China.

Leung TH, Wong W.

Chin J Integr Med. 2017 Jul;23(7):486-489. doi: 10.1007/s11655-017-2815-z. Epub 2017 Jun 17. Review. No abstract available.


MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis.

Mak CS, Yung MM, Hui LM, Leung LL, Liang R, Chen K, Liu SS, Qin Y, Leung TH, Lee KF, Chan KK, Ngan HY, Chan DW.

Mol Cancer. 2017 Jan 17;16(1):11. doi: 10.1186/s12943-017-0582-2.


Safety and Wound Outcomes Following Genetically Corrected Autologous Epidermal Grafts in Patients With Recessive Dystrophic Epidermolysis Bullosa.

Siprashvili Z, Nguyen NT, Gorell ES, Loutit K, Khuu P, Furukawa LK, Lorenz HP, Leung TH, Keene DR, Rieger KE, Khavari P, Lane AT, Tang JY, Marinkovich MP.

JAMA. 2016 Nov 1;316(17):1808-1817. doi: 10.1001/jama.2016.15588.


DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling.

Chan DW, Hui WW, Wang JJ, Yung MM, Hui LM, Qin Y, Liang RR, Leung TH, Xu D, Chan KK, Yao KM, Tsang BK, Ngan HY.

Oncogene. 2017 Mar;36(10):1404-1416. doi: 10.1038/onc.2016.307. Epub 2016 Sep 5.


A cellular, molecular, and pharmacological basis for appendage regeneration in mice.

Leung TH, Snyder ER, Liu Y, Wang J, Kim SK.

Genes Dev. 2015 Oct 15;29(20):2097-107. doi: 10.1101/gad.267724.115.


Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade.

Yung MM, Ross FA, Hardie DG, Leung TH, Zhan J, Ngan HY, Chan DW.

Integr Cancer Ther. 2016 Sep;15(3):376-89. doi: 10.1177/1534735415611747. Epub 2015 Oct 19.


Purified type I collagen wound matrix improves chronic wound healing in patients with recessive dystrophic epidermolysis bullosa.

Gorell ES, Leung TH, Khuu P, Lane AT.

Pediatr Dermatol. 2015 Mar-Apr;32(2):220-5. doi: 10.1111/pde.12492. Epub 2014 Dec 29.


Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling.

Cai PC, Shi L, Liu VW, Tang HW, Liu IJ, Leung TH, Chan KK, Yam JW, Yao KM, Ngan HY, Chan DW.

Oncotarget. 2014 Sep 15;5(17):7549-62.


Targeting estrogen receptor subtypes (ERα and ERβ) with selective ER modulators in ovarian cancer.

Chan KK, Leung TH, Chan DW, Wei N, Lau GT, Liu SS, Siu MK, Ngan HY.

J Endocrinol. 2014 May 12;221(2):325-36. doi: 10.1530/JOE-13-0500. Print 2014 May.


An open-label study to evaluate sildenafil for the treatment of lymphatic malformations.

Danial C, Tichy AL, Tariq U, Swetman GL, Khuu P, Leung TH, Benjamin L, Teng J, Vasanawala SS, Lane AT.

J Am Acad Dermatol. 2014 Jun;70(6):1050-7. doi: 10.1016/j.jaad.2014.02.005. Epub 2014 Mar 20.


Topical hypochlorite ameliorates NF-κB-mediated skin diseases in mice.

Leung TH, Zhang LF, Wang J, Ning S, Knox SJ, Kim SK.

J Clin Invest. 2013 Dec;123(12):5361-70. doi: 10.1172/JCI70895. Epub 2013 Nov 15.


The interaction between C35 and ΔNp73 promotes chemo-resistance in ovarian cancer cells.

Leung TH, Wong SC, Chan KK, Chan DW, Cheung AN, Ngan HY.

Br J Cancer. 2013 Aug 20;109(4):965-75. doi: 10.1038/bjc.2013.397. Epub 2013 Jul 23.


AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activity.

Kwan HT, Chan DW, Cai PC, Mak CS, Yung MM, Leung TH, Wong OG, Cheung AN, Ngan HY.

PLoS One. 2013;8(1):e53597. doi: 10.1371/journal.pone.0053597. Epub 2013 Jan 2.


Chronic health problems and health-related quality of life in Chinese children and adolescents: a population-based study in Hong Kong.

Lee SL, Cheung YF, Wong HS, Leung TH, Lam TH, Lau YL.

BMJ Open. 2013 Jan 3;3(1). pii: e001183. doi: 10.1136/bmjopen-2012-001183.


Targeting GRB7/ERK/FOXM1 signaling pathway impairs aggressiveness of ovarian cancer cells.

Chan DW, Hui WW, Cai PC, Liu MX, Yung MM, Mak CS, Leung TH, Chan KK, Ngan HY.

PLoS One. 2012;7(12):e52578. doi: 10.1371/journal.pone.0052578. Epub 2012 Dec 20. Erratum in: PLoS One. 2014;9(10):e110304.


Foetal exposure to maternal passive smoking is associated with childhood asthma, allergic rhinitis, and eczema.

Lee SL, Lam TH, Leung TH, Wong WH, Schooling M, Leung GM, Lau YL.

ScientificWorldJournal. 2012;2012:542983. doi: 10.1100/2012/542983. Epub 2012 Aug 13.


Increased expression of PITX2 transcription factor contributes to ovarian cancer progression.

Fung FK, Chan DW, Liu VW, Leung TH, Cheung AN, Ngan HY.

PLoS One. 2012;7(5):e37076. doi: 10.1371/journal.pone.0037076. Epub 2012 May 15.


Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells.

Lok GT, Chan DW, Liu VW, Hui WW, Leung TH, Yao KM, Ngan HY.

PLoS One. 2011;6(8):e23790. doi: 10.1371/journal.pone.0023790. Epub 2011 Aug 17.


Comparing chronic pain between fibrin sealant and suture fixation for bilayer polypropylene mesh inguinal hernioplasty: a randomized clinical trial.

Wong JU, Leung TH, Huang CC, Huang CS.

Am J Surg. 2011 Jul;202(1):34-8. doi: 10.1016/j.amjsurg.2010.05.004. Epub 2011 May 23.


Interaction of TAp73 and breast cancer-associated gene 3 enhances the sensitivity of cervical cancer cells in response to irradiation-induced apoptosis.

Leung TH, Ngan HY.

Cancer Res. 2010 Aug 15;70(16):6486-96. doi: 10.1158/0008-5472.CAN-10-0688. Epub 2010 Jul 20.


Deleted in liver cancer 2 suppresses cell growth via the regulation of the Raf-1-ERK1/2-p70S6K signalling pathway.

Leung TH, Yam JW, Chan LK, Ching YP, Ng IO.

Liver Int. 2010 Oct;30(9):1315-23. doi: 10.1111/j.1478-3231.2010.02307.x.


Loss of Programmed cell death 4 (Pdcd4) associates with the progression of ovarian cancer.

Wei NA, Liu SS, Leung TH, Tam KF, Liao XY, Cheung AN, Chan KK, Ngan HY.

Mol Cancer. 2009 Sep 3;8:70. doi: 10.1186/1476-4598-8-70.


Deleted in liver cancer 2 (DLC2) was dispensable for development and its deficiency did not aggravate hepatocarcinogenesis.

Yau TO, Leung TH, Lam S, Cheung OF, Tung EK, Khong PL, Lam A, Chung S, Ng IO.

PLoS One. 2009 Aug 10;4(8):e6566. doi: 10.1371/journal.pone.0006566.


Perianal eccrine adenocarcinoma.

Leung TH, Lee HH, Chang SC.

World J Surg Oncol. 2007 Sep 7;5:100.


Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma.

Yam JW, Ko FC, Chan CY, Yau TO, Tung EK, Leung TH, Jin DY, Ng IO.

Hepatology. 2006 Oct;44(4):881-90.


Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity.

Leung TH, Ching YP, Yam JW, Wong CM, Yau TO, Jin DY, Ng IO.

Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15207-12. Epub 2005 Oct 10.


Rho GTPase-activating protein deleted in liver cancer suppresses cell proliferation and invasion in hepatocellular carcinoma.

Wong CM, Yam JW, Ching YP, Yau TO, Leung TH, Jin DY, Ng IO.

Cancer Res. 2005 Oct 1;65(19):8861-8.


Achieving stability of lipopolysaccharide-induced NF-kappaB activation.

Covert MW, Leung TH, Gaston JE, Baltimore D.

Science. 2005 Sep 16;309(5742):1854-7.


One nucleotide in a kappaB site can determine cofactor specificity for NF-kappaB dimers.

Leung TH, Hoffmann A, Baltimore D.

Cell. 2004 Aug 20;118(4):453-64.


Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities.

Hoffmann A, Leung TH, Baltimore D.

EMBO J. 2003 Oct 15;22(20):5530-9.


Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma.

Ching YP, Wong CM, Chan SF, Leung TH, Ng DC, Jin DY, Ng IO.

J Biol Chem. 2003 Mar 21;278(12):10824-30. Epub 2003 Jan 16.


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