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Items: 1 to 50 of 1002

1.

CCN2 Mediates S1P-Induced Upregulation of COX2 Expression in Human Granulosa-Lutein Cells.

Hu LL, Chang HM, Yi Y, Liu Y, Taylor EL, Zheng LP, Leung PCK.

Cells. 2019 Nov 15;8(11). pii: E1445. doi: 10.3390/cells8111445.

2.

Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite.

Zhu Y, Klausen C, Zhou J, Guo X, Zhang Y, Zhu H, Li Z, Cheng JC, Xie S, Yang W, Li Y, Leung PCK.

Sci Rep. 2019 Oct 29;9(1):15528. doi: 10.1038/s41598-019-52108-6.

3.

Betacellulin enhances ovarian cancer cell migration by up-regulating Connexin43 via MEK-ERK signaling.

Zhao J, Klausen C, Yi Y, Cheng JC, Chang HM, Leung PCK.

Cell Signal. 2020 Jan;65:109439. doi: 10.1016/j.cellsig.2019.109439. Epub 2019 Oct 22.

PMID:
31654720
4.

To Reoffend or Not to Reoffend? An Investigation of Recidivism Among Individuals With Sexual Offense Histories and Psychopathy.

Leung PC, Looman J, Abracen J.

Sex Abuse. 2019 Sep 20:1079063219877173. doi: 10.1177/1079063219877173. [Epub ahead of print]

PMID:
31538857
5.

Elderly males with or without existing osteoporotic vertebral fracture have much lower future vertebral fracture risk than elderly females: the MrOS (Hong Kong) year-4 follow-up spine radiograph study.

Wáng YXJ, Che-Nordin N, Deng M, Griffith JF, Leung JCS, Kwok AWL, Leung PC, Kwok TCY.

Osteoporos Int. 2019 Sep 2. doi: 10.1007/s00198-019-05136-x. [Epub ahead of print]

PMID:
31478068
6.

TGF-β1 promotes hyaluronan synthesis by upregulating hyaluronan synthase 2 expression in human granulosa-lutein cells.

Wang F, Chang HM, Yi Y, Li H, Leung PCK.

Cell Signal. 2019 Nov;63:109392. doi: 10.1016/j.cellsig.2019.109392. Epub 2019 Aug 19.

PMID:
31437481
7.

Bone morphogenetic protein 6 affects cell-cell communication by altering the expression of Connexin43 in human granulosa-lutein cells.

Wu HC, Chang HM, Yi Y, Sun ZG, Lin YM, Lian F, Leung PCK.

Mol Cell Endocrinol. 2019 Dec 1;498:110548. doi: 10.1016/j.mce.2019.110548. Epub 2019 Aug 18.

PMID:
31434001
8.

Metronomic Chemotherapy for Children in Low- and Middle-Income Countries: Survey of Current Practices and Opinions of Pediatric Oncologists.

Revon-Rivière G, Banavali S, Heississen L, Gomez Garcia W, Abdolkarimi B, Vaithilingum M, Li CK, Leung PC, Malik P, Pasquier E, Epelman S, Chantada G, André N.

J Glob Oncol. 2019 Jul;5:1-8. doi: 10.1200/JGO.18.00244.

9.

Activin A promotes ovarian cancer cell migration by suppressing E-cadherin expression.

Yi Y, Cheng JC, Klausen C, Leung PCK.

Exp Cell Res. 2019 Sep 15;382(2):111471. doi: 10.1016/j.yexcr.2019.06.016. Epub 2019 Jun 20.

PMID:
31229504
10.

ID3 mediates the TGF-β1-induced suppression of matrix metalloproteinase-1 in human granulosa cells.

Li H, Chang HM, Shi Z, Leung PCK.

FEBS J. 2019 Nov;286(21):4310-4327. doi: 10.1111/febs.14964. Epub 2019 Jun 28.

PMID:
31215762
11.

SMAD-dependent signaling mediates morphogenetic protein 6-induced stimulation of connective tissue growth factor in luteinized human granulosa cells†.

Liu S, Chang HM, Yi Y, Yao YQ, Leung PCK.

Biol Reprod. 2019 Aug 1;101(2):445-456. doi: 10.1093/biolre/ioz108.

PMID:
31210269
12.

Kisspeptin regulation of human decidual stromal cells motility via FAK-Src intracellular tyrosine kinases.

Wu HM, Huang HY, Soong YK, Leung PCK, Wang HS.

Hum Reprod. 2019 Jul 8;34(7):1291-1301. doi: 10.1093/humrep/dez061.

PMID:
31188433
13.

Identification of potential metabolic biomarkers of polycystic ovary syndrome in follicular fluid by SWATH mass spectrometry.

Sun Z, Chang HM, Wang A, Song J, Zhang X, Guo J, Leung PCK, Lian F.

Reprod Biol Endocrinol. 2019 Jun 11;17(1):45. doi: 10.1186/s12958-019-0490-y.

14.

ALK4-SMAD2/3-SMAD4 signaling mediates the activin A-induced suppression of PTX3 in human granulosa-lutein cells.

Liu C, Chang HM, Yi Y, Fang Y, Zhao F, Leung PCK, Yang X.

Mol Cell Endocrinol. 2019 Aug 1;493:110485. doi: 10.1016/j.mce.2019.110485. Epub 2019 Jun 8.

PMID:
31185247
15.

Publisher Correction: GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.

Styrkarsdottir U, Stefansson OA, Gunnarsdottir K, Thorleifsson G, Lund SH, Stefansdottir L, Juliusson K, Agustsdottir AB, Zink F, Halldorsson GH, Ivarsdottir EV, Benonisdottir S, Jonsson H, Gylfason A, Norland K, Trajanoska K, Boer CG, Southam L, Leung JCS, Tang NLS, Kwok TCY, Lee JSW, Ho SC, Byrjalsen I, Center JR, Lee SH, Koh JM, Lohmander LS, Ho-Pham LT, Nguyen TV, Eisman JA, Woo J, Leung PC, Loughlin J, Zeggini E, Christiansen C, Rivadeneira F, van Meurs J, Uitterlinden AG, Mogensen B, Jonsson H, Ingvarsson T, Sigurdsson G, Benediktsson R, Sulem P, Jonsdottir I, Masson G, Holm H, Norddahl GL, Thorsteinsdottir U, Gudbjartsson DF, Stefansson K.

Nat Commun. 2019 May 24;10(1):2358. doi: 10.1038/s41467-019-10425-4.

16.

Lapatinib Inhibits Amphiregulin-induced BeWo Choriocarcinoma Cell Proliferation by Reducing ERK1/2 and AKT Signaling Pathways.

Pires LV, Yi Y, Cheng JC, Pizzolato LS, Cordero E, Leung PCK, Brum IS.

Anticancer Res. 2019 May;39(5):2377-2383. doi: 10.21873/anticanres.13355.

PMID:
31092430
17.

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.

Styrkarsdottir U, Stefansson OA, Gunnarsdottir K, Thorleifsson G, Lund SH, Stefansdottir L, Juliusson K, Agustsdottir AB, Zink F, Halldorsson GH, Ivarsdottir EV, Benonisdottir S, Jonsson H, Gylfason A, Norland K, Trajanoska K, Boer CG, Southam L, Leung JCS, Tang NLS, Kwok TCY, Lee JSW, Ho SC, Byrjalsen I, Center JR, Lee SH, Koh JM, Lohmander LS, Ho-Pham LT, Nguyen TV, Eisman JA, Woo J, Leung PC, Loughlin J, Zeggini E, Christiansen C, Rivadeneira F, van Meurs J, Uitterlinden AG, Mogensen B, Jonsson H, Ingvarsson T, Sigurdsson G, Benediktsson R, Sulem P, Jonsdottir I, Masson G, Holm H, Norddahl GL, Thorsteinsdottir U, Gudbjartsson DF, Stefansson K.

Nat Commun. 2019 May 3;10(1):2054. doi: 10.1038/s41467-019-09860-0. Erratum in: Nat Commun. 2019 May 24;10(1):2358.

18.

Palmitic acid causes insulin resistance in granulosa cells via activation of JNK.

Xu L, Wang W, Zhang X, Ke H, Qin Y, You L, Li W, Lu G, Chan WY, Leung PCK, Zhao S, Chen ZJ.

J Mol Endocrinol. 2019 Mar 1. pii: JME-18-0214.R3. doi: 10.1530/JME-18-0214. [Epub ahead of print]

PMID:
30913535
19.

Osteoporotic vertebral deformity with endplate/cortex fracture is associated with higher further vertebral fracture risk: the Ms. OS (Hong Kong) study results.

Wáng YXJ, Che-Nordin N, Deng M, Leung JCS, Kwok AWL, He LC, Griffith JF, Kwok TCY, Leung PC.

Osteoporos Int. 2019 Apr;30(4):897-905. doi: 10.1007/s00198-019-04856-4. Epub 2019 Jan 22.

PMID:
30666373
20.

BMP6 increases TGF-β1 production by up-regulating furin expression in human granulosa-lutein cells.

Zhang XY, Chang HM, Zhu H, Liu RZ, Leung PCK.

Cell Signal. 2019 Mar;55:109-118. doi: 10.1016/j.cellsig.2019.01.002. Epub 2019 Jan 8.

PMID:
30633987
21.

Pilot Studies on Two Complementary Bath Products for Atopic Dermatitis Children: Pine-Tar and Tea.

Hon KL, Ng WGG, Kung JSC, Leung PC, Leung TF.

Medicines (Basel). 2019 Jan 8;6(1). pii: E8. doi: 10.3390/medicines6010008.

22.

Neurotrophins and glial cell line-derived neurotrophic factor in the ovary: physiological and pathophysiological implications.

Chang HM, Wu HC, Sun ZG, Lian F, Leung PCK.

Hum Reprod Update. 2019 Mar 1;25(2):224-242. doi: 10.1093/humupd/dmy047.

23.

An innovative anti-cancer Chinese herbal formula exhibited multi-targeted efficacies in metastatic breast cancer mouse model.

Yue GG, Lee JK, Chan BC, Kwok HF, Hoi SW, Sze DM, Fung KP, Leung PC, Lau CB.

Chin Med. 2018 Dec 22;13:64. doi: 10.1186/s13020-018-0222-9. eCollection 2018.

24.

Prevalent osteoporotic vertebral fractures more likely involve the upper endplate than the lower endplate and even more so in males.

Che-Nordin N, Deng M, Griffith JF, Leung JCS, Kwok AWL, Zhu YQ, So RHY, Kwok TCY, Leung PC, Wáng YXJ.

Ann Transl Med. 2018 Nov;6(22):442. doi: 10.21037/atm.2018.10.61.

25.

Anti-Inflammatory Activities of Pentaherbs formula and Its Influence on Gut Microbiota in Allergic Asthma.

Tsang MS, Cheng SW, Zhu J, Atli K, Chan BC, Liu D, Chan HY, Sun X, Chu IM, Hon KL, Lam CW, Shaw PC, Leung PC, Wong CK.

Molecules. 2018 Oct 26;23(11). pii: E2776. doi: 10.3390/molecules23112776.

26.

Bone morphogenetic protein 2 increases lysyl oxidase activity via up-regulation of snail in human granulosa-lutein cells.

Bai L, Chang HM, Zhu YM, Leung PCK.

Cell Signal. 2019 Jan;53:201-211. doi: 10.1016/j.cellsig.2018.10.009. Epub 2018 Oct 12.

PMID:
30321593
27.

The HMGA2-IMP2 Pathway Promotes Granulosa Cell Proliferation in Polycystic Ovary Syndrome.

Li M, Zhao H, Zhao SG, Wei DM, Zhao YR, Huang T, Muhammad T, Yan L, Gao F, Li L, Lu G, Chan WY, Leung PCK, Dunaif A, Liu HB, Chen ZJ.

J Clin Endocrinol Metab. 2019 Apr 1;104(4):1049-1059. doi: 10.1210/jc.2018-00544.

28.

Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial.

von Dadelszen P, Magee LA, Benton SJ, Hu Y, Ansermino JM, Carleton B, Carter C, Douglas MJ, Janssen PA, Lee SK, Leung PCK, Li J, MacNab Y, Payne BA, Peng G, Rodger M, Skoll MA, Synnes A, Walley KR, Russell JA.

Pregnancy Hypertens. 2018 Jul;13:121-126. doi: 10.1016/j.preghy.2018.05.009. Epub 2018 May 28.

29.

All osteoporotically deformed vertebrae with >34% height loss have radiographically identifiable endplate/cortex fracture.

Deng M, Kwok TCY, Leung JCS, Leung PC, Wáng YXJ.

J Orthop Translat. 2018 Jul 6;14:63-66. doi: 10.1016/j.jot.2018.06.004. eCollection 2018 Jul. No abstract available.

30.

Inhibitory effect of different Dendrobium species on LPS-induced inflammation in macrophages via suppression of MAPK pathways.

Zeng Q, Ko CH, Siu WS, Li KK, Wong CW, Han XQ, Yang L, Lau CB, Hu JM, Leung PC.

Chin J Nat Med. 2018 Jul;16(7):481-489. doi: 10.1016/S1875-5364(18)30083-9.

PMID:
30080646
31.

TGF-β1 inhibits human trophoblast cell invasion by upregulating cyclooxygenase-2.

Yi Y, Cheng JC, Klausen C, Leung PCK.

Placenta. 2018 Aug;68:44-51. doi: 10.1016/j.placenta.2018.06.313. Epub 2018 Jun 30.

PMID:
30055669
32.

No Effects of Black Tea on Cognitive Decline Among Older US Men: A Prospective Cohort Study.

Feng L, Langsetmo L, Yaffe K, Sun Y, Fink HA, Shikany JM, Leung PC, Lane NE, Cauley JA; Osteoporotic Fractures in Men (MrOS) Study Group.

J Alzheimers Dis. 2018;65(1):99-105. doi: 10.3233/JAD-180103.

33.

GDNF-Induced Downregulation of miR-145-5p Enhances Human Oocyte Maturation and Cumulus Cell Viability.

Cui L, Fang L, Mao X, Chang HM, Leung PCK, Ye Y.

J Clin Endocrinol Metab. 2018 Jul 1;103(7):2510-2521. doi: 10.1210/jc.2017-02742.

PMID:
29897461
34.

Increased AIF-1-mediated TNF-α expression during implantation phase in IVF cycles with GnRH antagonist protocol.

Xu B, Zhou M, Wang J, Zhang D, Guo F, Si C, Leung PCK, Zhang A.

Hum Reprod. 2018 Jul 1;33(7):1270-1280. doi: 10.1093/humrep/dey119.

35.

Isodon eriocalyx and its bioactive component Eriocalyxin B enhance cytotoxic and apoptotic effects of gemcitabine in pancreatic cancer.

Li L, Zhao SL, Yue GGL, Wong TP, Pu JX, Sun HD, Fung KP, Leung PC, Han QB, Lau CBS, Leung PS.

Phytomedicine. 2018 May 15;44:56-64. doi: 10.1016/j.phymed.2018.03.055. Epub 2018 Mar 20.

PMID:
29895493
36.

Bone Morphogenetic Protein 2 Promotes Human Trophoblast Cell Invasion by Inducing Activin A Production.

Zhao HJ, Chang HM, Zhu H, Klausen C, Li Y, Leung PCK.

Endocrinology. 2018 Jul 1;159(7):2815-2825. doi: 10.1210/en.2018-00301.

PMID:
29846546
37.

BMP6 Downregulates GDNF Expression Through SMAD1/5 and ERK1/2 Signaling Pathways in Human Granulosa-Lutein Cells.

Zhang XY, Chang HM, Taylor EL, Liu RZ, Leung PCK.

Endocrinology. 2018 Aug 1;159(8):2926-2938. doi: 10.1210/en.2018-00189.

PMID:
29750278
38.

An in vitro and in vivo study of a 4-herb formula on the management of diet-induced metabolic syndrome.

Wat E, Wang Y, Chan K, Law HW, Koon CM, Lau KM, Leung PC, Yan C, Lau CBS.

Phytomedicine. 2018 Mar 15;42:112-125. doi: 10.1016/j.phymed.2018.03.028. Epub 2018 Mar 15.

PMID:
29655677
39.

Decreased PECAM1-mediated TGF-β1 expression in the mid-secretory endometrium in women with recurrent implantation failure.

Guo F, Si C, Zhou M, Wang J, Zhang D, Leung PCK, Xu B, Zhang A.

Hum Reprod. 2018 May 1;33(5):832-843. doi: 10.1093/humrep/dey022.

PMID:
29617817
40.

miR-106a Increases Granulosa Cell Viability and Is Downregulated in Women With Diminished Ovarian Reserve.

Hong L, Peng S, Li Y, Fang Y, Wang Q, Klausen C, Yin C, Wang S, Leung PCK, Yang X.

J Clin Endocrinol Metab. 2018 Jun 1;103(6):2157-2166. doi: 10.1210/jc.2017-02344.

PMID:
29590425
41.

Sophora flavescens protects against mycobacterial Trehalose Dimycolate-induced lung granuloma by inhibiting inflammation and infiltration of macrophages.

Liu D, Chan BC, Cheng L, Tsang MS, Zhu J, Wong CW, Jiao D, Chan HY, Leung PC, Lam CW, Wong CK.

Sci Rep. 2018 Mar 2;8(1):3903. doi: 10.1038/s41598-018-22286-w.

42.

SNAIL Mediates TGF-β1-Induced Downregulation of Pentraxin 3 Expression in Human Granulosa Cells.

Li H, Chang HM, Shi Z, Leung PCK.

Endocrinology. 2018 Apr 1;159(4):1644-1657. doi: 10.1210/en.2017-03127.

43.

Integrative Approach to Facilitate Fracture Healing: Topical Chinese Herbal Paste with Oral Strontium Ranelate.

Siu WS, Shiu HT, Ko CH, Shum WT, Yu HN, Lau CB, Hung LK, Leung PC.

Evid Based Complement Alternat Med. 2017;2017:9795806. doi: 10.1155/2017/9795806. Epub 2017 Dec 31.

44.

Neuroprotective effect of Da Chuanxiong Formula against cognitive and motor deficits in a rat controlled cortical impact model of traumatic brain injury.

Liu ZK, Ng CF, Shiu HT, Wong HL, Chin WC, Zhang JF, Lam PK, Poon WS, Lau CB, Leung PC, Ko CH.

J Ethnopharmacol. 2018 May 10;217:11-22. doi: 10.1016/j.jep.2018.02.004. Epub 2018 Feb 6.

PMID:
29425850
45.

Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling.

Zhao HJ, Klausen C, Li Y, Zhu H, Wang YL, Leung PCK.

Cell Death Dis. 2018 Feb 7;9(2):174. doi: 10.1038/s41419-017-0230-1.

46.

Follicular localization of growth differentiation factor 8 and its receptors in normal and polycystic ovary syndrome ovaries.

Lin TT, Chang HM, Hu XL, Leung PCK, Zhu YM.

Biol Reprod. 2018 May 1;98(5):683-694. doi: 10.1093/biolre/ioy029.

PMID:
29409020
47.

Osteoporotic Vertebral Fracture Prevalence in Elderly Chinese Men and Women: A Comparison of Endplate/Cortex Fracture-Based and Morphometrical Deformity-Based Methods.

Deng M, Zeng XJ, He LC, Leung JCS, Kwok AWL, Griffith JF, Kwok T, Leung PC, Wáng YXJ.

J Clin Densitom. 2019 Jul - Sep;22(3):409-419. doi: 10.1016/j.jocd.2017.11.004. Epub 2017 Dec 2.

PMID:
29307693
48.

TGF-β1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation.

Cheng JC, Yi Y, Chang HM, Leung PCK.

Cell Signal. 2018 Mar;43:55-61. doi: 10.1016/j.cellsig.2017.12.004. Epub 2017 Dec 18.

PMID:
29269046
49.

The roles of cellular and molecular components of a hematoma at early stage of bone healing.

Shiu HT, Leung PC, Ko CH.

J Tissue Eng Regen Med. 2018 Apr;12(4):e1911-e1925. doi: 10.1002/term.2622. Epub 2018 Jan 31. Review.

PMID:
29207216
50.

Dihydrofisetin exerts its anti-inflammatory effects associated with suppressing ERK/p38 MAPK and Heme Oxygenase-1 activation in lipopolysaccharide-stimulated RAW 264.7 macrophages and carrageenan-induced mice paw edema.

Li KK, Shen SS, Deng X, Shiu HT, Siu WS, Leung PC, Ko CH, Cheng BH.

Int Immunopharmacol. 2018 Jan;54:366-374. doi: 10.1016/j.intimp.2017.11.034. Epub 2017 Dec 1.

PMID:
29202300

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