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Management of severe hypertriglyceridemia due to lipoprotein lipase deficiency in children

Poon SWY, Leung KKY, Tung JYL.

Endocrinol Diabetes Metab Case Rep. 2019 Jul 26;2019(1):1-5. doi: 10.1530/EDM-19-0052.


History of malignancy and relevant symptoms may predict a positive computed tomography enterography in obscure gastrointestinal bleeds.

Leung KK, Khan U, Zhang M, McCurdy JD, James PD.

J Gastroenterol Hepatol. 2019 Sep;34(9):1511-1516. doi: 10.1111/jgh.14682. Epub 2019 Jun 6.


Experience of chromosomal microarray applied in prenatal and postnatal settings in Hong Kong.

Cheng SSW, Chan KYK, Leung KKP, Au PKC, Tam WK, Li SKM, Luk HM, Kan ASY, Chung BHY, Lo IFM, Tang MHY.

Am J Med Genet C Semin Med Genet. 2019 Jun;181(2):196-207. doi: 10.1002/ajmg.c.31697. Epub 2019 Mar 23.


Electrodepositing DNA Self-Assembled Monolayers on Au: Detailing the Influence of Electrical Potential Perturbation and Surface Crystallography.

Leung KK, Yu HZ, Bizzotto D.

ACS Sens. 2019 Feb 22;4(2):513-520. doi: 10.1021/acssensors.8b01695. Epub 2019 Feb 5.


Myocardial oedema in an 8-year-old Chinese boy with Idiopathic systemic capillary leak syndrome.

Leung KKY, Rosa Duque JS, Yu KM, Cheong KN, Chong PC, Ho MH, Chow PC.

BMC Pediatr. 2019 Jan 21;19(1):28. doi: 10.1186/s12887-019-1401-2.


Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome.

Leung KK, Nguyen A, Shi T, Tang L, Ni X, Escoubet L, MacBeth KJ, DiMartino J, Wells JA.

Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):695-700. doi: 10.1073/pnas.1813666116. Epub 2018 Dec 24.


Using Muscle Synergy to Evaluate the Neck Muscular Activities during Normal Swallowing.

Zhu M, Samuel OW, Yang Z, Lin W, Huang Z, Fang P, Tan J, Li P, Tong MC, Leung KK, Chen S, Li G.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:2454-2457. doi: 10.1109/EMBC.2018.8512760.


Inhibiting the integrated stress response pathway prevents aberrant chondrocyte differentiation thereby alleviating chondrodysplasia.

Wang C, Tan Z, Niu B, Tsang KY, Tai A, Chan WCW, Lo RLK, Leung KKH, Dung NWF, Itoh N, Zhang MQ, Chan D, Cheah KSE.

Elife. 2018 Jul 19;7. pii: e37673. doi: 10.7554/eLife.37673.


Red-eared zebra diagnosis: Case of relapsing polychondritis.

Leung KK, Edani S.

Can Fam Physician. 2018 May;64(5):363-367. No abstract available.


Reprogramming of Mouse Calvarial Osteoblasts into Induced Pluripotent Stem Cells.

Wang Y, Liu JA, Leung KKH, Sham MH, Chan D, Cheah KSE, Cheung M.

Stem Cells Int. 2018 Mar 12;2018:5280793. doi: 10.1155/2018/5280793. eCollection 2018.


We need a stroke system.

Leung GK.

Hong Kong Med J. 2018 Feb;24(1):9-10. doi: 10.12809/hkmj175075. No abstract available.


Predictive model integrating dynamic parameters for massive blood transfusion in major trauma patients: The Dynamic MBT score.

Lui CT, Wong OF, Tsui KL, Kam CW, Li SM, Cheng M, Leung KKG.

Am J Emerg Med. 2018 Aug;36(8):1444-1450. doi: 10.1016/j.ajem.2018.01.009. Epub 2018 Jan 4.


Recent development of luminescent rhenium(i) tricarbonyl polypyridine complexes as cellular imaging reagents, anticancer drugs, and antibacterial agents.

Lee LC, Leung KK, Lo KK.

Dalton Trans. 2017 Dec 21;46(47):16357-16380. doi: 10.1039/c7dt03465b. Epub 2017 Nov 7. Review.


Quantifying the Selective Modification of Au(111) Facets via Electrochemical and Electroless Treatments for Manipulating Gold Nanorod Surface Composition.

Fisher EA, Leung KK, Casanova-Moreno J, Masuda T, Young J, Bizzotto D.

Langmuir. 2017 Nov 14;33(45):12887-12896. doi: 10.1021/acs.langmuir.7b03021. Epub 2017 Nov 1.


Quick screening tool for patients with severe negative emotional reactions to chronic illness: psychometric study of the negative emotions due to chronic illness screening test (NECIS).

Huang YH, Wu CH, Chen HJ, Cheng YR, Hung FC, Leung KK, Lue BH, Chen CY, Chiu TY, Wu YC.

Fam Pract. 2018 Jan 16;35(1):34-40. doi: 10.1093/fampra/cmx076.


Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial magnetic resonance imaging study.

Kinnunen KM, Cash DM, Poole T, Frost C, Benzinger TLS, Ahsan RL, Leung KK, Cardoso MJ, Modat M, Malone IB, Morris JC, Bateman RJ, Marcus DS, Goate A, Salloway SP, Correia S, Sperling RA, Chhatwal JP, Mayeux RP, Brickman AM, Martins RN, Farlow MR, Ghetti B, Saykin AJ, Jack CR Jr, Schofield PR, McDade E, Weiner MW, Ringman JM, Thompson PM, Masters CL, Rowe CC, Rossor MN, Ourselin S, Fox NC; Dominantly Inherited Alzheimer Network (DIAN).

Alzheimers Dement. 2018 Jan;14(1):43-53. doi: 10.1016/j.jalz.2017.06.2268. Epub 2017 Jul 22.


Relationship between Coating-Induced Soot Aggregate Restructuring and Primary Particle Number.

Leung KK, Schnitzler EG, Dastanpour R, Rogak SN, Jäger W, Olfert JS.

Environ Sci Technol. 2017 Aug 1;51(15):8376-8383. doi: 10.1021/acs.est.7b01140. Epub 2017 Jul 19.


Review of Issues and Challenges of Practicing Emergency Medicine Above 30,000-Feet Altitude: 2 Anonymized Cases.

Hon KL, Leung KK.

Air Med J. 2017 Mar - Apr;36(2):67-70. doi: 10.1016/j.amj.2016.12.006.


A Comparison of Accelerated and Non-accelerated MRI Scans for Brain Volume and Boundary Shift Integral Measures of Volume Change: Evidence from the ADNI Dataset.

Manning EN, Leung KK, Nicholas JM, Malone IB, Cardoso MJ, Schott JM, Fox NC, Barnes J; Alzheimer’s Disease Neuroimaging Initiative.

Neuroinformatics. 2017 Apr;15(2):215-226. doi: 10.1007/s12021-017-9326-0.


White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy.

Fiford CM, Manning EN, Bartlett JW, Cash DM, Malone IB, Ridgway GR, Lehmann M, Leung KK, Sudre CH, Ourselin S, Biessels GJ, Carmichael OT, Fox NC, Cardoso MJ, Barnes J; Alzheimer's Disease Neuroimaging Initiative.

Hippocampus. 2017 Mar;27(3):249-262. doi: 10.1002/hipo.22690. Epub 2017 Jan 9.


Chaperones and intimate physical examinations: what do male and female patients want?

Fan VC, Choy HT, Kwok GY, Lam HG, Lim QY, Man YY, Tang CK, Wong CC, Yu YF, Leung GK.

Hong Kong Med J. 2017 Feb;23(1):35-40. doi: 10.12809/hkmj164899. Epub 2016 Dec 2.


Acoustic characteristics of clearly spoken English tense and lax vowels.

Leung KK, Jongman A, Wang Y, Sereno JA.

J Acoust Soc Am. 2016 Jul;140(1):45. doi: 10.1121/1.4954737.


Analysis of compound heterozygotes reveals that the mouse floxed Pax6 (tm1Ued) allele produces abnormal eye phenotypes.

Dorà NJ, Crookshanks AJ, Leung KK, Simpson TI, Mason JO, Price DJ, West JD.

Transgenic Res. 2016 Oct;25(5):679-92. doi: 10.1007/s11248-016-9962-4. Epub 2016 May 30.


Reproducibility of hippocampal atrophy rates measured with manual, FreeSurfer, AdaBoost, FSL/FIRST and the MAPS-HBSI methods in Alzheimer's disease.

Cover KS, van Schijndel RA, Versteeg A, Leung KK, Mulder ER, Jong RA, Visser PJ, Redolfi A, Revillard J, Grenier B, Manset D, Damangir S, Bosco P, Vrenken H, van Dijk BW, Frisoni GB, Barkhof F; Alzheimer's Disease Neuroimaging Initiative, neuGRID.

Psychiatry Res Neuroimaging. 2016 Jun 30;252:26-35. doi: 10.1016/j.pscychresns.2016.04.006. Epub 2016 May 11.


Photoactivatable cytotoxic agents derived from mitochondria-targeting luminescent iridium(III) poly(ethylene glycol) complexes modified with a nitrobenzyl linkage.

Tso KK, Leung KK, Liu HW, Lo KK.

Chem Commun (Camb). 2016 Mar 25;52(24):4557-60. doi: 10.1039/c6cc00918b.


Incidental finding of Chilaiditi's sign in an elderly individual with sarcopenia.

Leung KK, Frobb B, Fatmi SM, Martin B, Saint-Martin M.

Intern Emerg Med. 2016 Oct;11(7):1021-2. doi: 10.1007/s11739-015-1364-8. Epub 2015 Dec 8. No abstract available.


Binding of DNA-Intercalating Agents to Oxidized and Reduced Quinone Reductase 2.

Leung KK, Shilton BH.

Biochemistry. 2015 Dec 29;54(51):7438-48. doi: 10.1021/acs.biochem.5b00884. Epub 2015 Dec 14.


NADPH Oxidase-Dependent Reactive Oxygen Species Stimulate β-Cell Regeneration Through Differentiation of Endocrine Progenitors in Murine Pancreas.

Liang J, Wu SY, Zhang D, Wang L, Leung KK, Leung PS.

Antioxid Redox Signal. 2016 Mar 10;24(8):419-33. doi: 10.1089/ars.2014.6135. Epub 2015 Dec 18.


Differential hippocampal shapes in posterior cortical atrophy patients: A comparison with control and typical AD subjects.

Manning EN, Macdonald KE, Leung KK, Young J, Pepple T, Lehmann M, Zuluaga MA, Cardoso MJ, Schott JM, Ourselin S, Crutch S, Fox NC, Barnes J.

Hum Brain Mapp. 2015 Dec;36(12):5123-36. doi: 10.1002/hbm.22999. Epub 2015 Oct 13.


Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge.

Cash DM, Frost C, Iheme LO, Ünay D, Kandemir M, Fripp J, Salvado O, Bourgeat P, Reuter M, Fischl B, Lorenzi M, Frisoni GB, Pennec X, Pierson RK, Gunter JL, Senjem ML, Jack CR Jr, Guizard N, Fonov VS, Collins DL, Modat M, Cardoso MJ, Leung KK, Wang H, Das SR, Yushkevich PA, Malone IB, Fox NC, Schott JM, Ourselin S.

Neuroimage. 2015 Dec;123:149-64. doi: 10.1016/j.neuroimage.2015.07.087. Epub 2015 Aug 11.


Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2.

Jack CR Jr, Barnes J, Bernstein MA, Borowski BJ, Brewer J, Clegg S, Dale AM, Carmichael O, Ching C, DeCarli C, Desikan RS, Fennema-Notestine C, Fjell AM, Fletcher E, Fox NC, Gunter J, Gutman BA, Holland D, Hua X, Insel P, Kantarci K, Killiany RJ, Krueger G, Leung KK, Mackin S, Maillard P, Malone IB, Mattsson N, McEvoy L, Modat M, Mueller S, Nosheny R, Ourselin S, Schuff N, Senjem ML, Simonson A, Thompson PM, Rettmann D, Vemuri P, Walhovd K, Zhao Y, Zuk S, Weiner M.

Alzheimers Dement. 2015 Jul;11(7):740-56. doi: 10.1016/j.jalz.2015.05.002.


Autophagic adaptation is associated with exercise-induced fibre-type shifting in skeletal muscle.

Tam BT, Pei XM, Yu AP, Sin TK, Leung KK, Au KK, Chong JT, Yung BY, Yip SP, Chan LW, Wong CS, Siu PM.

Acta Physiol (Oxf). 2015 Jun;214(2):221-36. doi: 10.1111/apha.12503. Epub 2015 Apr 21.


Phosphorescent biscyclometallated iridium(III) ethylenediamine complexes functionalised with polar ester or carboxylate groups as bioimaging and visualisation reagents.

Tang TS, Leung KK, Louie MW, Liu HW, Cheng SH, Lo KK.

Dalton Trans. 2015 Mar 21;44(11):4945-56. doi: 10.1039/c4dt02890b.


Effects of changing from non-accelerated to accelerated MRI for follow-up in brain atrophy measurement.

Leung KK, Malone IM, Ourselin S, Gunter JL, Bernstein MA, Thompson PM, Jack CR Jr, Weiner MW, Fox NC; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage. 2015 Feb 15;107:46-53. doi: 10.1016/j.neuroimage.2014.11.049. Epub 2014 Dec 4.


A comparative analysis of behaviors and sexual affiliation networks among men who have sex with men in Hong Kong.

Leung KK, Poon CM, Lee SS.

Arch Sex Behav. 2015 Oct;44(7):2067-76. doi: 10.1007/s10508-014-0390-3. Epub 2014 Dec 2.


A new perspective on sexual mixing among men who have sex with men by body image.

Leung KK, Wong HT, Naftalin CM, Lee SS.

PLoS One. 2014 Nov 20;9(11):e113791. doi: 10.1371/journal.pone.0113791. eCollection 2014.


Quinone reductase 2 is an adventitious target of protein kinase CK2 inhibitors TBBz (TBI) and DMAT.

Leung KK, Shilton BH.

Biochemistry. 2015 Jan 13;54(1):47-59. doi: 10.1021/bi500959t. Epub 2014 Nov 18.


Measuring brain atrophy with a generalized formulation of the boundary shift integral.

Prados F, Cardoso MJ, Leung KK, Cash DM, Modat M, Fox NC, Wheeler-Kingshott CA, Ourselin S; Alzheimer's Disease Neuroimaging Initiative.

Neurobiol Aging. 2015 Jan;36 Suppl 1:S81-90. doi: 10.1016/j.neurobiolaging.2014.04.035. Epub 2014 Aug 29.


Accurate automatic estimation of total intracranial volume: a nuisance variable with less nuisance.

Malone IB, Leung KK, Clegg S, Barnes J, Whitwell JL, Ashburner J, Fox NC, Ridgway GR.

Neuroimage. 2015 Jan 1;104:366-72. doi: 10.1016/j.neuroimage.2014.09.034. Epub 2014 Oct 1.


T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunity.

Burger ML, Leung KK, Bennett MJ, Winoto A.

Elife. 2014 Sep 2;3. doi: 10.7554/eLife.03468.


R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia.

Slattery CF, Beck JA, Harper L, Adamson G, Abdi Z, Uphill J, Campbell T, Druyeh R, Mahoney CJ, Rohrer JD, Kenny J, Lowe J, Leung KK, Barnes J, Clegg SL, Blair M, Nicholas JM, Guerreiro RJ, Rowe JB, Ponto C, Zerr I, Kretzschmar H, Gambetti P, Crutch SJ, Warren JD, Rossor MN, Fox NC, Collinge J, Schott JM, Mead S.

Alzheimers Dement. 2014 Nov;10(6):602-608.e4. doi: 10.1016/j.jalz.2014.05.1751. Epub 2014 Aug 23.


Motor features in posterior cortical atrophy and their imaging correlates.

Ryan NS, Shakespeare TJ, Lehmann M, Keihaninejad S, Nicholas JM, Leung KK, Fox NC, Crutch SJ.

Neurobiol Aging. 2014 Dec;35(12):2845-2857. doi: 10.1016/j.neurobiolaging.2014.05.028. Epub 2014 Jun 6.


Comparative genomics of methicillin-resistant Staphylococcus aureus ST239: distinct geographical variants in Beijing and Hong Kong.

Wang Z, Zhou H, Wang H, Chen H, Leung KK, Tsui S, Ip M.

BMC Genomics. 2014 Jun 26;15:529. doi: 10.1186/1471-2164-15-529.


APOE ε4 is associated with disproportionate progressive hippocampal atrophy in AD.

Manning EN, Barnes J, Cash DM, Bartlett JW, Leung KK, Ourselin S, Fox NC; Alzheimer's Disease NeuroImaging Initiative.

PLoS One. 2014 May 30;9(5):e97608. doi: 10.1371/journal.pone.0097608. eCollection 2014. Erratum in: PLoS One. 2014;9(7):e104482.


Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.

Leung KK, Hause RJ Jr, Barkinge JL, Ciaccio MF, Chuu CP, Jones RB.

Mol Cell Proteomics. 2014 Jul;13(7):1705-23. doi: 10.1074/mcp.M113.034876. Epub 2014 Apr 12.


Therapeutic efficacy of improved α-fetoprotein promoter-mediated tBid delivered by folate-PEI600-cyclodextrin nanopolymer vector in hepatocellular carcinoma.

Hu BG, Liu LP, Chen GG, Ye CG, Leung KK, Ho RL, Lin MC, Lai PB.

Exp Cell Res. 2014 Jun 10;324(2):183-91. doi: 10.1016/j.yexcr.2014.04.005. Epub 2014 Apr 13.


Cyclometalated iridium(III) bipyridyl-phenylenediamine complexes with multicolor phosphorescence: synthesis, electrochemistry, photophysics, and intracellular nitric oxide sensing.

Law WH, Leung KK, Lee LC, Poon CS, Liu HW, Lo KK.

ChemMedChem. 2014 Jun;9(6):1316-29. doi: 10.1002/cmdc.201400040. Epub 2014 Mar 18.


Diffusion of two botulinum toxins type A on the forehead: double-blinded, randomized, controlled study.

Jiang HY, Chen S, Zhou J, Leung KK, Yu P.

Dermatol Surg. 2014 Feb;40(2):184-92. doi: 10.1111/dsu.12405. Epub 2014 Jan 18.


Automated template-based hippocampal segmentations from MRI: the effects of 1.5T or 3T field strength on accuracy.

Macdonald KE, Leung KK, Bartlett JW, Blair M, Malone IB, Barnes J, Ourselin S, Fox NC; Alzheimer’s Disease Neuroimaging Initiative.

Neuroinformatics. 2014 Jul;12(3):405-12. doi: 10.1007/s12021-013-9217-y.


Pathways to dementia diagnosis among South Asian Canadians.

McCleary L, Persaud M, Hum S, Pimlott NJ, Cohen CA, Koehn S, Leung KK, Dalziel WB, Kozak J, Emerson VF, Silvius JL, Garcia L, Drummond N.

Dementia (London). 2013 Nov;12(6):769-89. doi: 10.1177/1471301212444806. Epub 2012 Apr 26.


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