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BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells.

Lin TY, Chan HH, Chen SH, Sarvagalla S, Chen PS, Coumar MS, Cheng SM, Chang YC, Lin CH, Leung E, Cheung CHA.

Autophagy. 2019 Oct 15:1-18. doi: 10.1080/15548627.2019.1671643. [Epub ahead of print]


Lrrc7 mutant mice model developmental emotional dysregulation that can be alleviated by mGluR5 allosteric modulation.

Chong CH, Li Q, Mak PHS, Ng CCP, Leung EHW, Tan VH, Chan AKW, McAlonan G, Chan SY.

Transl Psychiatry. 2019 Oct 3;9(1):244. doi: 10.1038/s41398-019-0580-9.


Long-term aspirin use for cancer primary prevention: A protocol for updated systematic review and subgroup meta-analysis of randomized clinical trials.

Wu Q, Chen H, Yao X, Li T, Xu C, Wang J, Sui X, Leung EL.

Medicine (Baltimore). 2019 Sep;98(39):e17382. doi: 10.1097/MD.0000000000017382.


Digging deep into diabetes: achieving better glycemic control in diabetic patients in a resident-run clinic.

Hawatmeh S, Meier M, Leung E, Haque R, Kaur H, Asghar MF, Talebian A, Qaiyum O, Shailly R, Al-Abboud O, Patlolla K, Aziz AT, Kawsar HI.

J Community Hosp Intern Med Perspect. 2019 Sep 5;9(4):290-295. doi: 10.1080/20009666.2019.1650594. eCollection 2019.


Radiotherapy practices in postoperative endometrial cancer: A survey of the ABS membership.

Martell K, Doll C, Barnes EA, Phan T, Leung E, Taggar A.

Brachytherapy. 2019 Sep 11. pii: S1538-4721(19)30438-6. doi: 10.1016/j.brachy.2019.07.004. [Epub ahead of print]


Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation.

Hernandez W, Danahey K, Pei X, Yeo KJ, Leung E, Volchenboum SL, Ratain MJ, Meltzer DO, Stranger BE, Perera MA, O'Donnell PH.

Pharmacogenomics J. 2019 Sep 11. doi: 10.1038/s41397-019-0095-z. [Epub ahead of print]


Radioisotope Therapy of Bone Metastases-A Nuclear Medicine Perspective.

Leung E.

J Med Imaging Radiat Sci. 2019 Sep 6. pii: S1939-8654(19)30407-2. doi: 10.1016/j.jmir.2019.06.050. [Epub ahead of print] No abstract available.


Anticancer organorhodium and -iridium complexes with low toxicity in vivo but high potency in vitro: DNA damage, reactive oxygen species formation, and haemolytic activity.

Parveen S, Hanif M, Leung E, Tong KKH, Yang A, Astin J, De Zoysa GH, Steel TR, Goodman D, Movassaghi S, Söhnel T, Sarojini V, Jamieson SMF, Hartinger CG.

Chem Commun (Camb). 2019 Oct 3;55(80):12016-12019. doi: 10.1039/c9cc03822a.


Psychological morbidity in women diagnosed with ductal carcinoma in situ compared with women with early breast cancer receiving radiotherapy.

Pidduck W, Wan BA, Zhang L, Rakovitch E, Chow S, Chan S, Yee C, Drost L, Sousa P, Lewis D, Lam H, Leung E, Chow E.

Support Care Cancer. 2019 Aug 26. doi: 10.1007/s00520-019-05034-2. [Epub ahead of print]


Symptom clusters in patients with breast cancer receiving radiation therapy.

Chow S, Wan BA, Pidduck W, Zhang L, DeAngelis C, Chan S, Yee C, Drost L, Leung E, Sousa P, Lewis D, Lam H, Chow R, Lock M, Chow E.

Eur J Oncol Nurs. 2019 Oct;42:14-20. doi: 10.1016/j.ejon.2019.07.004. Epub 2019 Jul 10.


Imaging Cardiac Sarcoidosis With FLT-PET Compared With FDG/Perfusion-PET: A Prospective Pilot Study.

Martineau P, Pelletier-Galarneau M, Juneau D, Leung E, Nery PB, de Kemp R, Beanlands R, Birnie D.

JACC Cardiovasc Imaging. 2019 Aug 8. pii: S1936-878X(19)30612-6. doi: 10.1016/j.jcmg.2019.06.020. [Epub ahead of print] No abstract available.


Seasonal fluctuations in psychological distress amongst women diagnosed with early breast cancer receiving radiotherapy.

Pidduck W, Wan BA, Zhang L, Chow S, Yee C, Chan S, Drost L, Sousa P, Lewis D, Lam H, Leung E, Chow E.

Psychooncology. 2019 Oct;28(10):2091-2097. doi: 10.1002/pon.5199. Epub 2019 Aug 26.


Salvage Re-irradiation With Single-modality Interstitial Brachytherapy for the Treatment of Recurrent Gynaecological Tumours in the Pelvis: A Multi-institutional Study.

Raziee H, D'Souza D, Velker V, Barnes E, Taggar A, Mendez L, Leung E.

Clin Oncol (R Coll Radiol). 2019 Aug 8. pii: S0936-6555(19)30295-X. doi: 10.1016/j.clon.2019.07.015. [Epub ahead of print]


Safe Use of Radium-223 Dichloride (223RaCl2) Across a Wide Range of Clinical Scenarios, Incorporating a 10-year Single-Institution Radiation Safety Experience.

Aro JL, Dinning SI, Leung EY, Zuckier LS.

J Med Imaging Radiat Sci. 2019 Aug 2. pii: S1939-8654(19)30340-6. doi: 10.1016/j.jmir.2019.06.043. [Epub ahead of print]


Minimally invasive approach to the lumbosacral junction with a single position, 360° fusion.

Baum GR, Lin JD, Morr S, Osorio JA, Leung E, Schutzer RW, Lehman RA Jr.

J Spine Surg. 2019 Jun;5(Suppl 1):S68-S73. doi: 10.21037/jss.2019.04.09. Review.


Development of a Nonradioactive Platelet Serotonin Uptake and Release Assay by Micro-Liquid Chromatography Tandem Mass Spectrometry Using Minimal Blood Volume.

Chan SL, Yi X, Wysocki E, Bridgman R, Gutierrez J, Mikrut K, Leung EK, Yeo KJ, Miller JL.

Am J Clin Pathol. 2019 Jul 31. pii: aqz094. doi: 10.1093/ajcp/aqz094. [Epub ahead of print]


p53 sensitizes chemoresistant non-small cell lung cancer via elevation of reactive oxygen species and suppression of EGFR/PI3K/AKT signaling.

Zhang Y, Han CY, Duan FG, Fan XX, Yao XJ, Parks RJ, Tang YJ, Wang MF, Liu L, Tsang BK, Leung EL.

Cancer Cell Int. 2019 Jul 19;19:188. doi: 10.1186/s12935-019-0910-2. eCollection 2019.


Dosage Related Efficacy and Tolerability of Cannabidiol in Children With Treatment-Resistant Epileptic Encephalopathy: Preliminary Results of the CARE-E Study.

Huntsman RJ, Tang-Wai R, Alcorn J, Vuong S, Acton B, Corley S, Laprairie R, Lyon AW, Meier S, Mousseau DD, Newmeyer D, Prosser-Loose E, Seifert B, Tellez-Zenteno J, Huh L, Leung E, Major P.

Front Neurol. 2019 Jul 3;10:716. doi: 10.3389/fneur.2019.00716. eCollection 2019.


A single bacterium restores the microbiome dysbiosis to protect bones from destruction in a rat model of rheumatoid arthritis.

Pan H, Guo R, Ju Y, Wang Q, Zhu J, Xie Y, Zheng Y, Li T, Liu Z, Lu L, Li F, Tong B, Xiao L, Xu X, Leung EL, Li R, Yang H, Wang J, Zhou H, Jia H, Liu L.

Microbiome. 2019 Jul 17;7(1):107. doi: 10.1186/s40168-019-0719-1.


Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding.

Quek AJH, Mazzitelli BA, Wu G, Leung EWW, Caradoc-Davies TT, Lloyd GJ, Jeevarajah D, Conroy PJ, Sanderson-Smith M, Yuan Y, Ayinuola YA, Castellino FJ, Whisstock JC, Law RHP.

J Mol Biol. 2019 Sep 6;431(19):3804-3813. doi: 10.1016/j.jmb.2019.07.003. Epub 2019 Jul 8.


Total Synthesis and Structural Establishment/Revision of Antibiotics A54145.

Chen D, Chow HY, Po KHL, Ma W, Leung ELY, Sun Z, Liu M, Chen S, Li X.

Org Lett. 2019 Jul 19;21(14):5639-5644. doi: 10.1021/acs.orglett.9b01972. Epub 2019 Jul 2.


Patient-reported fatigue in breast cancer patients receiving radiation therapy.

Wan BA, Pidduck W, Zhang L, Nolen A, Drost L, Yee C, Chow S, Chan S, Soliman H, Leung E, Sousa P, Lewis D, DeAngelis C, Taylor P, Chow E.

Breast. 2019 Oct;47:10-15. doi: 10.1016/j.breast.2019.06.004. Epub 2019 Jun 19.


MRI-based interstitial brachytherapy for vaginal tumors: A multi-institutional study on practice patterns, contouring, and consensus definitions of target volumes.

Leung E, D'Souza D, Bachand F, Han K, Alfieri J, Huang F, Vigneault E, Barkati M, Wiebe EM, Foster W, Fortin I, Velker V, Bowes D, Barnes E, Patil N, Banerjee R, Barbera L, Ravi A.

Brachytherapy. 2019 Sep - Oct;18(5):598-605. doi: 10.1016/j.brachy.2019.05.007. Epub 2019 Jun 21.


Smartphone EEG and remote online interpretation for children with epilepsy in the Republic of Guinea: Quality, characteristics, and practice implications.

Williams JA, Cisse FA, Schaekermann M, Sakadi F, Tassiou NR, Hotan GC, Bah AK, Hamani ABD, Lim A, Leung ECW, Fantaneanu TA, Milligan TA, Khatri V, Hoch DB, Vyas MV, Lam AD, Cohen JM, Vogel AC, Law E, Mateen FJ; Guinea Epilepsy Project.

Seizure. 2019 Oct;71:93-99. doi: 10.1016/j.seizure.2019.05.025. Epub 2019 May 31.


Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.

Jin N, Bi A, Lan X, Xu J, Wang X, Liu Y, Wang T, Tang S, Zeng H, Chen Z, Tan M, Ai J, Xie H, Zhang T, Liu D, Huang R, Song Y, Leung EL, Yao X, Ding J, Geng M, Lin SH, Huang M.

Nat Commun. 2019 Jun 20;10(1):2701. doi: 10.1038/s41467-019-10427-2.


Long-term efficacy of Chinese medicine Bushen Capsule on cognition and brain activity in patients with amnestic mild cognitive impairment.

Zhang J, Yang C, Wei D, Li H, Leung EL, Deng Q, Liu Z, Fan XX, Zhang Z.

Pharmacol Res. 2019 Aug;146:104319. doi: 10.1016/j.phrs.2019.104319. Epub 2019 Jun 17.


Modelling disease risk for amyloid A (AA) amyloidosis in non-human primates using machine learning.

Leung ET, Raboin MJ, McKelvey J, Graham A, Lewis A, Prongay K, Cohen AM, Vinson A.

Amyloid. 2019 Sep;26(3):139-147. doi: 10.1080/13506129.2019.1625038. Epub 2019 Jun 18.


Vaginal brachytherapy alone for patients with Stage II endometrial cancer with inner half cervical stromal invasion.

Barnes EA, Parra-Herran C, Martell K, Barbera L, Taggar A, Leung E.

Brachytherapy. 2019 Sep - Oct;18(5):606-611. doi: 10.1016/j.brachy.2019.05.003. Epub 2019 Jun 11.


Direct Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis by Use of pncA PCR Sequencing.

Tam KK, Leung KS, Siu GK, Chang KC, Wong SS, Ho PL, Leung EK, Yam WC.

J Clin Microbiol. 2019 Jul 26;57(8). pii: e00145-19. doi: 10.1128/JCM.00145-19. Print 2019 Aug.


Symptoms Predictive of Overall Quality of Life Using the Edmonton Symptom Assessment Scale in Breast Cancer Patients Receiving Radiotherapy.

Chow S, Wan BA, Pidduck W, Zhang L, DeAngelis C, Chan S, Yee C, Drost L, Leung E, Sousa P, Lewis D, Lam H, Chow R, Lock M, Chow E.

Clin Breast Cancer. 2019 May 18. pii: S1526-8209(19)30055-2. doi: 10.1016/j.clbc.2019.05.007. [Epub ahead of print]


Emergence of Carbapenem-Resistant Acinetobacter baumannii ST195 Harboring blaOXA-23 Isolated from Bacteremia in Hong Kong.

Leung EC, Leung PH, Lai RW.

Microb Drug Resist. 2019 Oct;25(8):1199-1203. doi: 10.1089/mdr.2018.0433. Epub 2019 Jun 3.


Recommendations for integrating physiotherapy into an interprofessional outpatient care setting for people living with HIV: a qualitative study.

deBoer H, Cudd S, Andrews M, Leung E, Petrie A, Chan Carusone S, O'Brien KK.

BMJ Open. 2019 May 24;9(5):e026827. doi: 10.1136/bmjopen-2018-026827.


Developing a Short Multidimensional Measure of Pain Self-efficacy: The Chronic Pain Self-efficacy Scale-Short Form.

Cheng ST, Chen PP, Chow YF, Chung JWY, Law ACB, Lee JSW, Leung EMF, Tam CWC.

Gerontologist. 2019 May 21. pii: gnz041. doi: 10.1093/geront/gnz041. [Epub ahead of print]


Compound C620-0696, a new potent inhibitor targeting BPTF, the chromatin-remodeling factor in non-small-cell lung cancer.

Xu J, Wang Q, Leung ELH, Li Y, Fan X, Wu Q, Yao X, Liu L.

Front Med. 2019 May 18. doi: 10.1007/s11684-019-0694-8. [Epub ahead of print]


Can intracellular drug delivery using hyaluronic acid functionalised pH-sensitive liposomes overcome gemcitabine resistance in pancreatic cancer?

Tang M, Svirskis D, Leung E, Kanamala M, Wang H, Wu Z.

J Control Release. 2019 Jul 10;305:89-100. doi: 10.1016/j.jconrel.2019.05.018. Epub 2019 May 13.


Evaluation of Time to Surgery and Its Effect on Prognosis in Head and Neck Cancer.

Tham T, Leung E, Khaymovich J, Mitha S, Olson C, Wotman M, Teegala S, Coury J, Costantino P.

Oncol Res Treat. 2019;42(7-8):387-395. doi: 10.1159/000500207. Epub 2019 May 10.


A dynamic thermoregulatory material inspired by squid skin.

Leung EM, Colorado Escobar M, Stiubianu GT, Jim SR, Vyatskikh AL, Feng Z, Garner N, Patel P, Naughton KL, Follador M, Karshalev E, Trexler MD, Gorodetsky AA.

Nat Commun. 2019 Apr 29;10(1):1947. doi: 10.1038/s41467-019-09589-w.


Glycogenic hepatopathy as an unusual etiology of deranged liver function in a patient with type 1 diabetes: A case report.

Lui DT, Woo YC, Chow WS, Lee CH, Lee AC, Leung EK, Tan KC, Lam KS, Lam JK.

Medicine (Baltimore). 2019 Apr;98(17):e15296. doi: 10.1097/MD.0000000000015296.


Physical Activity of Children with Physical Disabilities: Associations with Environmental and Behavioral Variables at Home and School.

Sit C, Li R, McKenzie TL, Cerin E, Wong S, Sum R, Leung E.

Int J Environ Res Public Health. 2019 Apr 17;16(8). pii: E1394. doi: 10.3390/ijerph16081394.


Intraoperative 360-deg three-dimensional transvaginal ultrasound during needle insertions for high-dose-rate transperineal interstitial gynecologic brachytherapy of vaginal tumors.

Rodgers JR, Bax J, Surry K, Velker V, Leung E, D'Souza D, Fenster A.

J Med Imaging (Bellingham). 2019 Apr;6(2):025001. doi: 10.1117/1.JMI.6.2.025001. Epub 2019 Apr 8.


Natural History of Perinatal and Infantile Hypophosphatasia: A Retrospective Study.

Whyte MP, Leung E, Wilcox WR, Liese J, Argente J, Martos-Moreno GÁ, Reeves A, Fujita KP, Moseley S, Hofmann C; Study 011-10 Investigators.

J Pediatr. 2019 Jun;209:116-124.e4. doi: 10.1016/j.jpeds.2019.01.049. Epub 2019 Apr 9.


Cordycepin Inhibits Drug-resistance Non-small Cell Lung Cancer Progression by Activating AMPK Signaling Pathway.

Wei C, Yao X, Jiang Z, Wang Y, Zhang D, Chen X, Fan X, Xie C, Cheng J, Fu J, Leung EL.

Pharmacol Res. 2019 Jun;144:79-89. doi: 10.1016/j.phrs.2019.03.011. Epub 2019 Apr 8.


When Pap Testing Fails to Prevent Cervix Cancer: A Qualitative Study of the Experience of Screened Women Under 50 with Advanced Cervix Cancer in Canada.

Corkum MT, Shaddick H, Jewlal E, Patil N, Leung E, Sugimoto A, McGee J, Prefontaine M, D'Souza D.

Cureus. 2019 Jan 24;11(1):e3950. doi: 10.7759/cureus.3950.


Evaluation of the prognostic utility of the combination of platelet count with mean platelet volume as a prognostic indicator in head and neck cancer.

Tham T, Leung E, Olson C, Wotman M, Khaymovich J, Coury J, Teegala S, Costantino P.

Mol Clin Oncol. 2019 Apr;10(4):457-462. doi: 10.3892/mco.2019.1813. Epub 2019 Feb 22.


I Can't See.

Leung EH, Stout JT.

J Pediatr Ophthalmol Strabismus. 2019 Mar 19;56(2):71. doi: 10.3928/01913913-20190212-01. No abstract available.


Prevalence and Predictive Factors of Concurrent Cervical Spinal Cord Compression in Adult Spinal Deformity.

Shimizu T, Lehman RA Jr, Pongmanee S, Alex Sielatycki J, Leung E, Riew KD, Lenke LG.

Spine (Phila Pa 1976). 2019 Aug 1;44(15):1049-1056. doi: 10.1097/BRS.0000000000003007.


"Fungating" tumour? No, it's bacterial!

Balakrishnan M, Phan YC, McIlroy B, Leung E.

BMJ Case Rep. 2019 Feb 25;12(2). pii: e227876. doi: 10.1136/bcr-2018-227876.


Coping With Imminent Death: Thematic Content Analysis on Narratives by Japanese Soldiers in World War II.

Leung E, Chalupa A.

Omega (Westport). 2019 Feb;78(3):211-301. doi: 10.1177/0030222815612786. Epub 2015 Nov 3.


Development of Contextually-relevant Sexuality Education: Lessons from a Comprehensive Review of Adolescent Sexuality Education Across Cultures.

Leung H, Shek DTL, Leung E, Shek EYW.

Int J Environ Res Public Health. 2019 Feb 20;16(4). pii: E621. doi: 10.3390/ijerph16040621. Review.

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