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Items: 1 to 50 of 139

1.

Comparison of Recommendations for Treatment of Chronic Hepatitis C Virus Infection in Children and Adolescents: A Position Paper of the Global Federation of International Societies of International Societies of Pediatric Gastroenterology, Hepatology and Nutrition (FISPGHAN).

Indolfi G, Fischler B, Gonzalez-Peralta RP, Ciocca M, Porta G, Neelam M, Guindi ME, Kelly D, Ni YH, Sibal A, Leung DH, Chang MH; Hepatitis Expert Team of the Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition (FISPGHAN).

J Pediatr Gastroenterol Nutr. 2020 Mar 20. doi: 10.1097/MPG.0000000000002710. [Epub ahead of print]

PMID:
32205770
2.

Heterogeneous Liver on Research Ultrasound Identifies Children with Cystic Fibrosis at High Risk of Advanced Liver Disease: Interim Results of a Prospective Observational Case-Controlled Study.

Siegel MJ, Freeman AJ, Ye W, Palermo JJ, Molleston JP, Paranjape SM, Stoll J, Leung DH, Masand P, Karmazyn B, Harned R, Ling SC, Navarro OM, Karnsakul W, Alazraki A, Schwarzenberg SJ, Seidel FG, Towbin A, Alonso EM, Nicholas JL, Murray KF, Otto RK, Sherker AH, Magee JC, Narkewicz MR; CFLD Network.

J Pediatr. 2020 Apr;219:62-69.e4. doi: 10.1016/j.jpeds.2019.12.033. Epub 2020 Feb 12.

PMID:
32061406
3.

Towards an improved understanding of drug excipient interactions to enable rapid optimization of nanosuspension formulations.

Ferrar JA, Sellers BD, Chan C, Leung DH.

Int J Pharm. 2020 Mar 30;578:119094. doi: 10.1016/j.ijpharm.2020.119094. Epub 2020 Jan 29.

PMID:
32006625
4.

Chronic liver disease and impaired hepatic glycogen metabolism in argininosuccinate lyase deficiency.

Burrage LC, Madan S, Li X, Ali S, Mohammad M, Stroup BM, Jiang MM, Cela R, Bertin T, Jin Z, Dai J, Guffey D, Finegold M; Members of the Urea Cycle Disorders Consortium (UCDC), Nagamani S, Minard CG, Marini J, Masand P, Schady D, Shneider BL, Leung DH, Bali D, Lee B.

JCI Insight. 2020 Feb 27;5(4). pii: 132342. doi: 10.1172/jci.insight.132342.

5.

Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure.

Hayden HS, Eng A, Pope CE, Brittnacher MJ, Vo AT, Weiss EJ, Hager KR, Martin BD, Leung DH, Heltshe SL, Borenstein E, Miller SI, Hoffman LR.

Nat Med. 2020 Feb;26(2):215-221. doi: 10.1038/s41591-019-0714-x. Epub 2020 Jan 20.

PMID:
31959989
6.

Liver Ultrasound Patterns in Children With Cystic Fibrosis Correlate With Noninvasive Tests of Liver Disease.

Ling SC, Ye W, Leung DH, Navarro OM, Weymann A, Karnsakul W, Freeman AJ, Magee JC, Narkewicz MR.

J Pediatr Gastroenterol Nutr. 2019 Sep;69(3):351-357. doi: 10.1097/MPG.0000000000002413.

PMID:
31436672
7.

Refusal bias in HIV data from the Demographic and Health Surveys: Evaluation, critique and recommendations.

Adegboye OA, Fujii T, Leung DH.

Stat Methods Med Res. 2020 Mar;29(3):811-826. doi: 10.1177/0962280219844536. Epub 2019 May 9.

PMID:
31072213
8.

Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis.

Lewindon PJ, Puertolas-Lopez MV, Ramm LE, Noble C, Pereira TN, Wixey JA, Hartel GF, Calvopina DA, Leung DH, Ramm GA.

Clin Gastroenterol Hepatol. 2019 Nov;17(12):2561-2569.e5. doi: 10.1016/j.cgh.2019.03.015. Epub 2019 Mar 15.

PMID:
30880274
9.

A Multidisciplinary Approach to Pretransplant and Posttransplant Management of Cystic Fibrosis-Associated Liver Disease.

Freeman AJ, Sellers ZM, Mazariegos G, Kelly A, Saiman L, Mallory G, Ling SC, Narkewicz MR, Leung DH.

Liver Transpl. 2019 Apr;25(4):640-657. doi: 10.1002/lt.25421. Epub 2019 Mar 20.

PMID:
30697907
10.

Pulmonary findings in infants with cystic fibrosis during the first year of life: Results from the Baby Observational and Nutrition Study (BONUS) cohort study.

Goetz D, Kopp BT, Salvator A, Moore-Clingenpeel M, McCoy K, Leung DH, Kloster M, Ramsey BR, Heltshe SH, Borowitz D.

Pediatr Pulmonol. 2019 May;54(5):581-586. doi: 10.1002/ppul.24261. Epub 2019 Jan 22.

11.

Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration.

Nishiguchi MA, Spencer CA, Leung DH, Leung TH.

Cell Rep. 2018 Dec 26;25(13):3898. doi: 10.1016/j.celrep.2018.12.056. No abstract available.

12.

Urinary metabolomics reveals unique metabolic signatures in infants with cystic fibrosis.

Kopp BT, Joseloff E, Goetz D, Ingram B, Heltshe SL, Leung DH, Ramsey BW, McCoy K, Borowitz D.

J Cyst Fibros. 2019 Jul;18(4):507-515. doi: 10.1016/j.jcf.2018.10.016. Epub 2018 Nov 23.

PMID:
30477895
13.

Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir and With or Without Ribavirin for Adolescents With HCV Genotype 1 or 4.

Leung DH, Wirth S, Yao BB, Viani RM, Gonzalez-Peralta RP, Jonas MM, Lobritto SJ, Narkewicz MR, Sokal E, Fortuny C, Hsu EK, Del Valle-Segarra A, Zha J, Larsen L, Liu L, Shuster DL, Cohen DE, Rosenthal P.

Hepatol Commun. 2018 Oct 5;2(11):1311-1319. doi: 10.1002/hep4.1250. eCollection 2018 Nov.

14.

Obliterative Portal Venopathy Without Cirrhosis Is Prevalent in Pediatric Cystic Fibrosis Liver Disease With Portal Hypertension.

Wu H, Vu M, Dhingra S, Ackah R, Goss JA, Rana A, Quintanilla N, Patel K, Leung DH.

Clin Gastroenterol Hepatol. 2019 Sep;17(10):2134-2136. doi: 10.1016/j.cgh.2018.10.046. Epub 2018 Nov 4.

PMID:
30404037
15.

Placebo-Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome.

Shneider BL, Spino C, Kamath BM, Magee JC, Bass LM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Murray KF, Loomes KM, Rosenthal P, Karpen SJ, Leung DH, Guthery SL, Thomas D, Sherker AH, Sokol RJ; Childhood Liver Disease Research Network.

Hepatol Commun. 2018 Sep 24;2(10):1184-1198. doi: 10.1002/hep4.1244. eCollection 2018 Oct.

16.

Hepatitis B and C.

Mysore KR, Leung DH.

Clin Liver Dis. 2018 Nov;22(4):703-722. doi: 10.1016/j.cld.2018.06.002. Epub 2018 Aug 22. Review.

PMID:
30266158
17.

Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration.

Nishiguchi MA, Spencer CA, Leung DH, Leung TH.

Cell Rep. 2018 Sep 25;24(13):3383-3392.e5. doi: 10.1016/j.celrep.2018.08.054. Erratum in: Cell Rep. 2018 Dec 26;25(13):3898.

18.

Hepatic Steatosis Is Prevalent Following Orthotopic Liver Transplantation in Children With Cystic Fibrosis.

Cortes-Santiago N, Leung DH, Castro E, Finegold M, Wu H, Patel KR.

J Pediatr Gastroenterol Nutr. 2019 Jan;68(1):96-103. doi: 10.1097/MPG.0000000000002154.

PMID:
30234762
19.

MicroRNA Sequencing Identifies a Serum MicroRNA Panel, Which Combined With Aspartate Aminotransferase to Platelet Ratio Index Can Detect and Monitor Liver Disease in Pediatric Cystic Fibrosis.

Calvopina DA, Chatfield MD, Weis A, Coleman MA, Fernandez-Rojo MA, Noble C, Ramm LE, Leung DH, Lewindon PJ, Ramm GA.

Hepatology. 2018 Dec;68(6):2301-2316. doi: 10.1002/hep.30156. Epub 2018 Nov 15.

PMID:
30014495
20.

Erythropoietic Protoporphyria: Initial Diagnosis With Cholestatic Liver Disease.

Coffey A, Leung DH, Quintanilla NM.

Pediatrics. 2018 Apr;141(Suppl 5):S445-S450. doi: 10.1542/peds.2016-1625.

21.

Pancreatic Enzyme Replacement Therapy Use in Infants With Cystic Fibrosis Diagnosed by Newborn Screening.

Gelfond D, Heltshe SL, Skalland M, Heubi JE, Kloster M, Leung DH, Ramsey BW, Borowitz D; BONUS Study Investigators.

J Pediatr Gastroenterol Nutr. 2018 Apr;66(4):657-663. doi: 10.1097/MPG.0000000000001829.

22.

Cystic Fibrosis-related cirrhosis.

Leung DH, Narkewicz MR.

J Cyst Fibros. 2017 Nov;16 Suppl 2:S50-S61. doi: 10.1016/j.jcf.2017.07.002. Review.

23.

Variceal Hemorrhage and Adverse Liver Outcomes in Patients With Cystic Fibrosis Cirrhosis.

Ye W, Narkewicz MR, Leung DH, Karnsakul W, Murray KF, Alonso EM, Magee JC, Schwarzenberg SJ, Weymann A, Molleston JP; CFLDnet research group.

J Pediatr Gastroenterol Nutr. 2018 Jan;66(1):122-127. doi: 10.1097/MPG.0000000000001728.

24.

Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation.

Ma MKF, Lau EYT, Leung DHW, Lo J, Ho NPY, Cheng LKW, Ma S, Lin CH, Copland JA, Ding J, Lo RCL, Ng IOL, Lee TKW.

J Hepatol. 2017 Nov;67(5):979-990. doi: 10.1016/j.jhep.2017.06.015. Epub 2017 Jun 22.

PMID:
28647567
25.

Hepatic fibrosis scores and serum biomarkers in pediatric hepatology.

Leung DH.

Clin Liver Dis (Hoboken). 2017 May 26;9(5):125-130. doi: 10.1002/cld.634. eCollection 2017 May. Review. No abstract available.

26.

The intestinal microbiome and paediatric liver disease.

Leung DH, Yimlamai D.

Lancet Gastroenterol Hepatol. 2017 Jun;2(6):446-455. doi: 10.1016/S2468-1253(16)30241-2. Review.

PMID:
28497760
27.

Effects of Diagnosis by Newborn Screening for Cystic Fibrosis on Weight and Length in the First Year of Life.

Leung DH, Heltshe SL, Borowitz D, Gelfond D, Kloster M, Heubi JE, Stalvey M, Ramsey BW; Baby Observational and Nutrition Study (BONUS) Investigators of the Cystic Fibrosis Foundation Therapeutics Development Network.

JAMA Pediatr. 2017 Jun 1;171(6):546-554. doi: 10.1001/jamapediatrics.2017.0206.

28.

Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists.

Cox JM, Chu HD, Chelliah MV, Debenham JS, Eagen K, Lan P, Lombardo M, London C, Plotkin MA, Shah U, Sun Z, Vaccaro HM, Venkatraman S, Suzuki T, Wang N, Ashley ER, Crespo A, Madeira M, Leung DH, Alleyne C, Ogawa AM, Souza S, Thomas-Fowlkes B, Di Salvo J, Weinglass A, Kirkland M, Pachanski M, Powles MA, Tozzo E, Akiyama TE, Ujjainwalla F, Tata JR, Sinz CJ.

ACS Med Chem Lett. 2016 Nov 17;8(1):49-54. doi: 10.1021/acsmedchemlett.6b00360. eCollection 2017 Jan 12.

29.

Development of a Convenient In Vitro Gel Diffusion Model for Predicting the In Vivo Performance of Subcutaneous Parenteral Formulations of Large and Small Molecules.

Leung DH, Kapoor Y, Alleyne C, Walsh E, Leithead A, Habulihaz B, Salituro GM, Bak A, Rhodes T.

AAPS PharmSciTech. 2017 Aug;18(6):2203-2213. doi: 10.1208/s12249-016-0698-5. Epub 2017 Jan 9.

PMID:
28070846
30.

Joint spatial time-series epidemiological analysis of malaria and cutaneous leishmaniasis infection.

Adegboye OA, Al-Saghir M, Leung DH.

Epidemiol Infect. 2017 Mar;145(4):685-700. doi: 10.1017/S0950268816002764. Epub 2016 Dec 1.

PMID:
27903308
31.

A 10-Year united network for organ sharing review of mortality and risk factors in young children awaiting liver transplantation.

Leung DH, Narang A, Minard CG, Hiremath G, Goss JA, Shepherd R.

Liver Transpl. 2016 Nov;22(11):1584-1592. doi: 10.1002/lt.24605. Erratum in: Liver Transpl. 2017 Sep;23 (9):1235.

32.

50 Years Ago in TheJournal ofPediatrics: Macroscopic Cysts of the Pancreas in a Case of Cystic Fibrosis.

Leung DH, Grand RJ.

J Pediatr. 2016 Sep;176:133. doi: 10.1016/j.jpeds.2016.03.051. No abstract available.

PMID:
27568251
33.

Hepatitis B immunity in the pediatric liver transplant population.

Patel SS, Leung DH.

Curr Opin Pediatr. 2016 Oct;28(5):653-8. doi: 10.1097/MOP.0000000000000391. Review.

PMID:
27367054
34.

Primary prophylaxis of variceal bleeding in children and the role of MesoRex Bypass: Summary of the Baveno VI Pediatric Satellite Symposium.

Shneider BL, de Ville de Goyet J, Leung DH, Srivastava A, Ling SC, Duché M, McKiernan P, Superina R, Squires RH, Bosch J, Groszmann R, Sarin SK, de Franchis R, Mazariegos GV.

Hepatology. 2016 Apr;63(4):1368-80. doi: 10.1002/hep.28153. Epub 2015 Oct 23. Review.

PMID:
26358549
35.

Baseline Ultrasound and Clinical Correlates in Children with Cystic Fibrosis.

Leung DH, Ye W, Molleston JP, Weymann A, Ling S, Paranjape SM, Romero R, Schwarzenberg SJ, Palermo J, Alonso EM, Murray KF, Marshall BC, Sherker AH, Siegel MJ, Krishnamurthy R, Harned R, Karmazyn B, Magee JC, Narkewicz MR; Cystic Fibrosis Liver Disease Network (CFLD NET).

J Pediatr. 2015 Oct;167(4):862-868.e2. doi: 10.1016/j.jpeds.2015.06.062. Epub 2015 Aug 5.

36.

Aspartate aminotransferase to platelet ratio and fibrosis-4 as biomarkers in biopsy-validated pediatric cystic fibrosis liver disease.

Leung DH, Khan M, Minard CG, Guffey D, Ramm LE, Clouston AD, Miller G, Lewindon PJ, Shepherd RW, Ramm GA.

Hepatology. 2015 Nov;62(5):1576-83. doi: 10.1002/hep.28016. Epub 2015 Sep 28. Erratum in: Hepatology. 2017 Jan;65(1):397.

PMID:
26223427
37.

Drug-induced liver injury in children.

Amin MD, Harpavat S, Leung DH.

Curr Opin Pediatr. 2015 Oct;27(5):625-33. doi: 10.1097/MOP.0000000000000264. Review.

PMID:
26208237
38.

Standardization of Research-Quality Anthropometric Measurement of Infants and Implementation in a Multicenter Study.

Coburn-Miller C, Casey S, Luong Q, Cameron N, Hocevar-Trnka J, Leung DH, Gelfond D, Heubi JE, Ramsey B, Borowitz D.

Clin Transl Sci. 2015 Aug;8(4):330-3. doi: 10.1111/cts.12283. Epub 2015 Jun 5.

39.

Reply to L'Huillier et al.

Leung DH, Ton-That M, Economides JM, Healy CM.

Am J Transplant. 2015 Aug;15(8):2277. doi: 10.1111/ajt.13311. Epub 2015 May 26. No abstract available.

40.

Hepatitis D in Children.

Xue MM, Glenn JS, Leung DH.

J Pediatr Gastroenterol Nutr. 2015 Sep;61(3):271-81. doi: 10.1097/MPG.0000000000000859.

PMID:
25988557
41.

Modulating Drug Release and Enhancing the Oral Bioavailability of Torcetrapib with Solid Lipid Dispersion Formulations.

Liu Y, Salituro GM, Lee KJ, Bak A, Leung DH.

AAPS PharmSciTech. 2015 Oct;16(5):1091-100. doi: 10.1208/s12249-015-0299-8. Epub 2015 Feb 18.

42.

High prevalence of hepatitis B nonimmunity in vaccinated pediatric liver transplant recipients.

Leung DH, Ton-That M, Economides JM, Healy CM.

Am J Transplant. 2015 Feb;15(2):535-40. doi: 10.1111/ajt.12987. Epub 2015 Jan 21.

43.

Hepatitis C in the pediatric population: transmission, natural history, treatment and liver transplantation.

Khaderi S, Shepherd R, Goss JA, Leung DH.

World J Gastroenterol. 2014 Aug 28;20(32):11281-6. doi: 10.3748/wjg.v20.i32.11281. Review.

44.

Starting an academic career and starting a family: challenges and some potential solutions.

Mann M, Goetz D, Leung DH, Borowitz D.

J Pediatr. 2014 Sep;165(3):430-1. doi: 10.1016/j.jpeds.2014.05.044. No abstract available.

PMID:
25152148
45.

A new and improved method for the preparation of drug nanosuspension formulations using acoustic mixing technology.

Leung DH, Lamberto DJ, Liu L, Kwong E, Nelson T, Rhodes T, Bak A.

Int J Pharm. 2014 Oct 1;473(1-2):10-9. doi: 10.1016/j.ijpharm.2014.05.003. Epub 2014 Jun 28.

PMID:
24984068
46.

Early attained weight and length predict growth faltering better than velocity measures in infants with CF.

Heltshe SL, Borowitz DS, Leung DH, Ramsey B, Mayer-Hamblett N.

J Cyst Fibros. 2014 Dec;13(6):723-9. doi: 10.1016/j.jcf.2014.05.009. Epub 2014 Jun 7.

47.

Angiosarcoma successfully treated with liver transplantation and sirolimus.

Xue M, Masand P, Thompson P, Finegold M, Leung DH.

Pediatr Transplant. 2014 Jun;18(4):E114-9. doi: 10.1111/petr.12245. Epub 2014 Mar 19.

PMID:
24641525
48.

Use of allopurinol in children with acute lymphoblastic leukemia to reduce skewed thiopurine metabolism.

Brackett J, Schafer ES, Leung DH, Bernhardt MB.

Pediatr Blood Cancer. 2014 Jun;61(6):1114-7. doi: 10.1002/pbc.24913. Epub 2013 Dec 27.

PMID:
24376133
49.

Unrecognized hepatitis B in pre-screened children with hematologic and oncologic conditions.

Leung DH, Ahamba DC, Pillai LN, Khan MF, Smith EO, Mahoney DH.

Pediatr Blood Cancer. 2014 May;61(5):865-8. doi: 10.1002/pbc.24853. Epub 2013 Nov 19.

PMID:
24249385
50.

Shrinkage empirical likelihood estimator in longitudinal analysis with time-dependent covariates--application to modeling the health of Filipino children.

Leung DH, Small DS, Qin J, Zhu M.

Biometrics. 2013 Sep;69(3):624-32. doi: 10.1111/biom.12039. Epub 2013 Jul 11.

PMID:
23845158

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