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Items: 1 to 50 of 80


Inter-muscular adipose tissue is associated with adipose tissue inflammation and poorer functional performance in central adiposity.

Lim JP, Chong MS, Tay L, Yang YX, Leung BP, Yeo A, Yew S, Tan CH, Lim WS.

Arch Gerontol Geriatr. 2019 Mar - Apr;81:1-7. doi: 10.1016/j.archger.2018.11.006. Epub 2018 Nov 13.


A brief report on the clinical trial on neural mobilization exercise for joint pain in patients with rheumatoid arthritis.

Lau YN, Ng J, Lee SY, Li LC, Kwan CM, Fan SM, Leung BPL, Lo CN.

Z Rheumatol. 2019 Jun;78(5):474-478. doi: 10.1007/s00393-018-0521-7.


High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease.

Mrdjen D, Pavlovic A, Hartmann FJ, Schreiner B, Utz SG, Leung BP, Lelios I, Heppner FL, Kipnis J, Merkler D, Greter M, Becher B.

Immunity. 2018 Mar 20;48(3):599. doi: 10.1016/j.immuni.2018.02.014. No abstract available.


High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease.

Mrdjen D, Pavlovic A, Hartmann FJ, Schreiner B, Utz SG, Leung BP, Lelios I, Heppner FL, Kipnis J, Merkler D, Greter M, Becher B.

Immunity. 2018 Feb 20;48(2):380-395.e6. doi: 10.1016/j.immuni.2018.01.011. Epub 2018 Feb 6. Erratum in: Immunity. 2018 Mar 20;48(3):599.


Association of nutrition and immune-endocrine dysfunction with muscle mass and performance in cognitively impaired older adults.

Tay L, Leung BP, Wee S, Tay KS, Ali N, Chan M, Lim WS.

Arch Gerontol Geriatr. 2018 Mar - Apr;75:20-27. doi: 10.1016/j.archger.2017.11.008. Epub 2017 Nov 16.


The effect of nerve mobilization exercise in patients with rheumatoid arthritis: a pilot study.

Lo CN, Xia G, Leung BP.

Reumatismo. 2017 Sep 21;69(3):111-118. doi: 10.4081/reumatismo.2017.918.


Passing the Threshold of One Justice System to the Next: Challenges of Emerging Young Adults in Hong Kong's Adult Criminal Justice Process.

Cheng KK, Leung BP.

Int J Offender Ther Comp Criminol. 2018 Jul;62(9):2650-2668. doi: 10.1177/0306624X17723640. Epub 2017 Aug 2.


Associations of B cell-activating factor (BAFF) and anti-BAFF autoantibodies with disease activity in multi-ethnic Asian systemic lupus erythematosus patients in Singapore.

Howe HS, Thong BYH, Kong KO, Chng HH, Lian TY, Chia FL, Tay KSS, Lau TC, Law WG, Koh ET, Leung BP.

Clin Exp Immunol. 2017 Sep;189(3):298-303. doi: 10.1111/cei.12975. Epub 2017 May 2.


Amyloid Precursor Protein Translation Is Regulated by a 3'UTR Guanine Quadruplex.

Crenshaw E, Leung BP, Kwok CK, Sharoni M, Olson K, Sebastian NP, Ansaloni S, Schweitzer-Stenner R, Akins MR, Bevilacqua PC, Saunders AJ.

PLoS One. 2015 Nov 30;10(11):e0143160. doi: 10.1371/journal.pone.0143160. eCollection 2015.


Sex-specific differences in risk factors for sarcopenia amongst community-dwelling older adults.

Tay L, Ding YY, Leung BP, Ismail NH, Yeo A, Yew S, Tay KS, Tan CH, Chong MS.

Age (Dordr). 2015 Dec;37(6):121. doi: 10.1007/s11357-015-9860-3. Epub 2015 Nov 25.


Monocyte chemoattractant protein-1: a proinflammatory cytokine elevated in sarcopenic obesity.

Lim JP, Leung BP, Ding YY, Tay L, Ismail NH, Yeo A, Yew S, Chong MS.

Clin Interv Aging. 2015 Mar 25;10:605-9. doi: 10.2147/CIA.S78901. eCollection 2015.


Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

Guillot-Sestier MV, Doty KR, Gate D, Rodriguez J Jr, Leung BP, Rezai-Zadeh K, Town T.

Neuron. 2015 Feb 4;85(3):534-48. doi: 10.1016/j.neuron.2014.12.068. Epub 2015 Jan 22.


TLR cross-talk confers specificity to innate immunity.

Tan RS, Ho B, Leung BP, Ding JL.

Int Rev Immunol. 2014 Nov-Dec;33(6):443-53. doi: 10.3109/08830185.2014.921164. Epub 2014 Jun 9. Review.


Receptor-interacting protein 2 gene silencing attenuates allergic airway inflammation.

Goh FY, Cook KL, Upton N, Tao L, Lah LC, Leung BP, Wong WS.

J Immunol. 2013 Sep 1;191(5):2691-9. doi: 10.4049/jimmunol.1202416. Epub 2013 Aug 5.


Laminin drives survival signals to promote a contractile smooth muscle phenotype and airway hyperreactivity.

Tran T, Teoh CM, Tam JK, Qiao Y, Chin CY, Chong OK, Stewart AG, Harris T, Wong WS, Guan SP, Leung BP, Gerthoffer WT, Unruh H, Halayko AJ.

FASEB J. 2013 Oct;27(10):3991-4003. doi: 10.1096/fj.12-221341. Epub 2013 Jun 11.


The synergy in cytokine production through MyD88-TRIF pathways is co-ordinated with ERK phosphorylation in macrophages.

Suet Ting Tan R, Lin B, Liu Q, Tucker-Kellogg L, Ho B, Leung BP, Ling Ding J.

Immunol Cell Biol. 2013 May;91(5):377-87. doi: 10.1038/icb.2013.13. Epub 2013 Apr 9.


Effect of continuous oral suctioning on the development of ventilator-associated pneumonia: a pilot randomized controlled trial.

Chow MC, Kwok SM, Luk HW, Law JW, Leung BP.

Int J Nurs Stud. 2012 Nov;49(11):1333-41. doi: 10.1016/j.ijnurstu.2012.06.003. Epub 2012 Jun 28.


Sphingosine kinase and sphingosine-1-phosphate receptors: novel therapeutic targets of rheumatoid arthritis?

Lai WQ, Chia FL, Leung BP.

Future Med Chem. 2012 Apr;4(6):727-33. doi: 10.4155/fmc.12.28. Review.


Urine sVCAM-1 and sICAM-1 levels are elevated in lupus nephritis.

Howe HS, Kong KO, Thong BY, Law WG, Chia FL, Lian TY, Lau TC, Chng HH, Leung BP.

Int J Rheum Dis. 2012 Feb;15(1):13-6. doi: 10.1111/j.1756-185X.2012.01720.x.


Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB.

Goh FY, Upton N, Guan S, Cheng C, Shanmugam MK, Sethi G, Leung BP, Wong WS.

Eur J Pharmacol. 2012 Mar 15;679(1-3):109-16. doi: 10.1016/j.ejphar.2012.01.002. Epub 2012 Jan 20.


Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function.

Xuzhu G, Komai-Koma M, Leung BP, Howe HS, McSharry C, McInnes IB, Xu D.

Ann Rheum Dis. 2012 Jan;71(1):129-35. doi: 10.1136/ard.2011.149831. Epub 2011 Sep 27.


Anti-malarial drug artesunate attenuates experimental allergic asthma via inhibition of the phosphoinositide 3-kinase/Akt pathway.

Cheng C, Ho WE, Goh FY, Guan SP, Kong LR, Lai WQ, Leung BP, Wong WS.

PLoS One. 2011;6(6):e20932. doi: 10.1371/journal.pone.0020932. Epub 2011 Jun 9.


Role of sphingosine kinase and sphingosine-1-phosphate in inflammatory arthritis.

Lai WQ, Melendez AJ, Leung BP.

World J Biol Chem. 2010 Nov 26;1(11):321-6. doi: 10.4331/wjbc.v1.i11.321.


TrkB Isoforms Differentially Affect AICD Production through Their Intracellular Functional Domains.

Ansaloni S, Leung BP, Sebastian NP, Samudralwar R, Gadaleta M, Saunders AJ.

Int J Alzheimers Dis. 2011 Feb 24;2011:729382. doi: 10.4061/2011/729382.


Phosphodiesterase 4 (PDE4) regulation of proinflammatory cytokine and chemokine release from rheumatoid synovial membrane.

Crilly A, Robertson SE, Reilly JH, Gracie JA, Lai WQ, Leung BP, Life PF, McInnes IB.

Ann Rheum Dis. 2011 Jun;70(6):1130-7. doi: 10.1136/ard.2010.134825. Epub 2011 Feb 21.


Sphingosine kinase and sphingosine 1-phosphate in asthma.

Lai WQ, Wong WS, Leung BP.

Biosci Rep. 2011 Apr;31(2):145-50. doi: 10.1042/BSR20100087. Review.


Heat-shock protein 60 translocates to the surface of apoptotic cells and differentiated megakaryocytes and stimulates phagocytosis.

Goh YC, Yap CT, Huang BH, Cronshaw AD, Leung BP, Lai PB, Hart SP, Dransfield I, Ross JA.

Cell Mol Life Sci. 2011 May;68(9):1581-92. doi: 10.1007/s00018-010-0534-0. Epub 2010 Oct 16.


Serum monocyte chemotactic protein-1 concentrations distinguish patients with ankylosing spondylitis from patients with mechanical low back pain.

Romero-Sanchez C, Tsou HK, Jan MS, Wong RH, Chang IC, Londoño J, Valle-Oñate R, Howe HS, Yu D, Leung BP, Wei JC.

J Spinal Disord Tech. 2011 May;24(3):202-7. doi: 10.1097/BSD.0b013e3181e15cc8.


SARM inhibits both TRIF- and MyD88-mediated AP-1 activation.

Peng J, Yuan Q, Lin B, Panneerselvam P, Wang X, Luan XL, Lim SK, Leung BP, Ho B, Ding JL.

Eur J Immunol. 2010 Jun;40(6):1738-47. doi: 10.1002/eji.200940034.


IL-33 exacerbates autoantibody-induced arthritis.

Xu D, Jiang HR, Li Y, Pushparaj PN, Kurowska-Stolarska M, Leung BP, Mu R, Tay HK, McKenzie AN, McInnes IB, Melendez AJ, Liew FY.

J Immunol. 2010 Mar 1;184(5):2620-6. doi: 10.4049/jimmunol.0902685. Epub 2010 Feb 5.


Distinct roles of sphingosine kinase 1 and 2 in murine collagen-induced arthritis.

Lai WQ, Irwan AW, Goh HH, Melendez AJ, McInnes IB, Leung BP.

J Immunol. 2009 Aug 1;183(3):2097-103. doi: 10.4049/jimmunol.0804376. Epub 2009 Jul 13.


A novel antiinflammatory role for andrographolide in asthma via inhibition of the nuclear factor-kappaB pathway.

Bao Z, Guan S, Cheng C, Wu S, Wong SH, Kemeny DM, Leung BP, Wong WS.

Am J Respir Crit Care Med. 2009 Apr 15;179(8):657-65. doi: 10.1164/rccm.200809-1516OC. Epub 2009 Feb 6.


Enhanced expression of interferon-inducible protein-10 correlates with disease activity and clinical manifestations in systemic lupus erythematosus.

Kong KO, Tan AW, Thong BY, Lian TY, Cheng YK, Teh CL, Koh ET, Chng HH, Law WG, Lau TC, Leong KP, Leung BP, Howe HS.

Clin Exp Immunol. 2009 Apr;156(1):134-40. doi: 10.1111/j.1365-2249.2009.03880.x. Epub 2009 Jan 23.


Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis.

Lai WQ, Irwan AW, Goh HH, Howe HS, Yu DT, Valle-Oñate R, McInnes IB, Melendez AJ, Leung BP.

J Immunol. 2008 Dec 1;181(11):8010-7.


The role of sphingosine kinase in a murine model of allergic asthma.

Lai WQ, Goh HH, Bao Z, Wong WS, Melendez AJ, Leung BP.

J Immunol. 2008 Mar 15;180(6):4323-9.


Interleukin 27 attenuates collagen-induced arthritis.

Niedbala W, Cai B, Wei X, Patakas A, Leung BP, McInnes IB, Liew FY.

Ann Rheum Dis. 2008 Oct;67(10):1474-9. doi: 10.1136/ard.2007.083360. Epub 2008 Jan 16.


IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production.

Verri WA Jr, Cunha TM, Ferreira SH, Wei X, Leung BP, Fraser A, McInnes IB, Liew FY, Cunha FQ.

Eur J Immunol. 2007 Dec;37(12):3373-80.


IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells.

Niedbala W, Wei XQ, Cai B, Hueber AJ, Leung BP, McInnes IB, Liew FY.

Eur J Immunol. 2007 Nov;37(11):3021-9. Erratum in: Eur J Immunol. 2007 Nov;37(11):3293.


Glycogen synthase kinase-3beta inhibition attenuates asthma in mice.

Bao Z, Lim S, Liao W, Lin Y, Thiemermann C, Leung BP, Wong WS.

Am J Respir Crit Care Med. 2007 Sep 1;176(5):431-8. Epub 2007 Jun 7.


CD4+CD25+ regulatory T cells in health and disease.

Liu H, Leung BP.

Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):519-24. Review.


Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection.

Culshaw S, Leung BP, Gracie JA, Campbell CC, Thomson D, Gemmell C, Liew FY, McInnes IB.

Eur J Immunol. 2005 May;35(5):1438-44.


Novel immunofluorescence assay using recombinant nucleocapsid-spike fusion protein as antigen to detect antibodies against severe acute respiratory syndrome coronavirus.

He Q, Manopo I, Lu L, Leung BP, Chng HH, Ling AE, Chee LL, Chan SW, Ooi EE, Sin YL, Ang B, Kwang J.

Clin Diagn Lab Immunol. 2005 Feb;12(2):321-8.


An anti-inflammatory role for a phosphoinositide 3-kinase inhibitor LY294002 in a mouse asthma model.

Duan W, Aguinaldo Datiles AM, Leung BP, Vlahos CJ, Wong WS.

Int Immunopharmacol. 2005 Mar;5(3):495-502.


Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome.

Reghunathan R, Jayapal M, Hsu LY, Chng HH, Tai D, Leung BP, Melendez AJ.

BMC Immunol. 2005 Jan 18;6:2.


Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice.

Duan W, Chan JH, McKay K, Crosby JR, Choo HH, Leung BP, Karras JG, Wong WS.

Am J Respir Crit Care Med. 2005 Mar 15;171(6):571-8. Epub 2004 Nov 19.


Transforming growth factor beta-1 and gene polymorphisms in oriental ankylosing spondylitis.

Howe HS, Cheung PL, Kong KO, Badsha H, Thong BY, Leong KP, Koh ET, Lian TY, Cheng YK, Lam S, Teo D, Lau TC, Leung BP.

Rheumatology (Oxford). 2005 Jan;44(1):51-4. Epub 2004 Oct 12.


Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells.

Maffia P, Brewer JM, Gracie JA, Ianaro A, Leung BP, Mitchell PJ, Smith KM, McInnes IB, Garside P.

J Immunol. 2004 Jul 1;173(1):151-6.


A novel therapy of murine collagen-induced arthritis with soluble T1/ST2.

Leung BP, Xu D, Culshaw S, McInnes IB, Liew FY.

J Immunol. 2004 Jul 1;173(1):145-50.


Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model.

Duan W, Chan JH, Wong CH, Leung BP, Wong WS.

J Immunol. 2004 Jun 1;172(11):7053-9.

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