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Items: 10

1.

Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD.

Leuenroth SJ, Bencivenga N, Chahboune H, Hyder F, Crews CM.

Nephrol Dial Transplant. 2010 Jul;25(7):2187-94. doi: 10.1093/ndt/gfp777. Epub 2010 Feb 4.

2.

Targeting cyst initiation in ADPKD.

Leuenroth SJ, Crews CM.

J Am Soc Nephrol. 2009 Jan;20(1):1-3. doi: 10.1681/ASN.2008101118. Epub 2008 Dec 31. No abstract available.

3.

Triptolide reduces cystogenesis in a model of ADPKD.

Leuenroth SJ, Bencivenga N, Igarashi P, Somlo S, Crews CM.

J Am Soc Nephrol. 2008 Sep;19(9):1659-62. doi: 10.1681/ASN.2008030259. Epub 2008 Jul 23.

4.

Triptolide-induced transcriptional arrest is associated with changes in nuclear substructure.

Leuenroth SJ, Crews CM.

Cancer Res. 2008 Jul 1;68(13):5257-66. doi: 10.1158/0008-5472.CAN-07-6207.

5.

Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease.

Leuenroth SJ, Okuhara D, Shotwell JD, Markowitz GS, Yu Z, Somlo S, Crews CM.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4389-94. Epub 2007 Mar 6.

6.

Studies on calcium dependence reveal multiple modes of action for triptolide.

Leuenroth SJ, Crews CM.

Chem Biol. 2005 Dec;12(12):1259-68.

7.

TNFalpha-induced suppression of PMN apoptosis is mediated through interleukin-8 production.

Dunican AL, Leuenroth SJ, Grutkoski P, Ayala A, Simms HH.

Shock. 2000 Sep;14(3):284-8; discussion 288-9.

PMID:
11028544
8.

Suppression of PMN apoptosis by hypoxia is dependent on Mcl-1 and MAPK activity.

Leuenroth SJ, Grutkoski PS, Ayala A, Simms HH.

Surgery. 2000 Aug;128(2):171-7.

PMID:
10922988
9.

The loss of Mcl-1 expression in human polymorphonuclear leukocytes promotes apoptosis.

Leuenroth SJ, Grutkoski PS, Ayala A, Simms HH.

J Leukoc Biol. 2000 Jul;68(1):158-66.

PMID:
10914504
10.

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