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Managing birds of conservation concern on sandy shores: How much room for future conservation actions is there?

Maslo B, Leu K, Pover T, Weston MA, Schlacher TA.

Ecol Evol. 2018 Oct 17;8(22):10976-10988. doi: 10.1002/ece3.4564. eCollection 2018 Nov.


Optimizing conservation benefits for threatened beach fauna following severe natural disturbances.

Maslo B, Leu K, Pover T, Weston MA, Gilby BL, Schlacher TA.

Sci Total Environ. 2019 Feb 1;649:661-671. doi: 10.1016/j.scitotenv.2018.08.319. Epub 2018 Aug 25.


Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide, and bevacizumab or placebo.

Ellingson BM, Abrey LE, Garcia J, Chinot O, Wick W, Saran F, Nishikawa R, Henriksson R, Mason WP, Harris RJ, Leu K, Woodworth DC, Mehta A, Raymond C, Chakhoyan A, Pope WB, Cloughesy TF.

Neuro Oncol. 2018 Oct 9;20(11):1525-1535. doi: 10.1093/neuonc/noy064.


Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma.

Ellingson BM, Aftab DT, Schwab GM, Hessel C, Harris RJ, Woodworth DC, Leu K, Chakhoyan A, Raymond C, Drappatz J, de Groot J, Prados MD, Reardon DA, Schiff D, Chamberlain M, Mikkelsen T, Desjardins A, Holland J, Ping J, Weitzman R, Wen PY, Cloughesy TF.

Neuro Oncol. 2018 Sep 3;20(10):1411-1418. doi: 10.1093/neuonc/noy054.


Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI).

Harris RJ, Yao J, Chakhoyan A, Raymond C, Leu K, Liau LM, Nghiemphu PL, Lai A, Salamon N, Pope WB, Cloughesy TF, Ellingson BM.

Magn Reson Med. 2018 Nov;80(5):1962-1978. doi: 10.1002/mrm.27204. Epub 2018 Apr 6.


Improved Spatiotemporal Resolution of Dynamic Susceptibility Contrast Perfusion MRI in Brain Tumors Using Simultaneous Multi-Slice Echo-Planar Imaging.

Chakhoyan A, Leu K, Pope WB, Cloughesy TF, Ellingson BM.

AJNR Am J Neuroradiol. 2018 Jan;39(1):43-45. doi: 10.3174/ajnr.A5433. Epub 2017 Oct 26.


Diffusion MRI Phenotypes Predict Overall Survival Benefit from Anti-VEGF Monotherapy in Recurrent Glioblastoma: Converging Evidence from Phase II Trials.

Ellingson BM, Gerstner ER, Smits M, Huang RY, Colen R, Abrey LE, Aftab DT, Schwab GM, Hessel C, Harris RJ, Chakhoyan A, Gahrmann R, Pope WB, Leu K, Raymond C, Woodworth DC, de Groot J, Wen PY, Batchelor TT, van den Bent MJ, Cloughesy TF.

Clin Cancer Res. 2017 Oct 1;23(19):5745-5756. doi: 10.1158/1078-0432.CCR-16-2844. Epub 2017 Jun 27.


Perfusion and diffusion MRI signatures in histologic and genetic subtypes of WHO grade II-III diffuse gliomas.

Leu K, Ott GA, Lai A, Nghiemphu PL, Pope WB, Yong WH, Liau LM, Cloughesy TF, Ellingson BM.

J Neurooncol. 2017 Aug;134(1):177-188. doi: 10.1007/s11060-017-2506-9. Epub 2017 May 25.


Chirosurveillance: The use of native bats to detect invasive agricultural pests.

Maslo B, Valentin R, Leu K, Kerwin K, Hamilton GC, Bevan A, Fefferman NH, Fonseca DM.

PLoS One. 2017 Mar 29;12(3):e0173321. doi: 10.1371/journal.pone.0173321. eCollection 2017.


High-Fat Diet in the Absence of Obesity Does Not Aggravate Surgically Induced Lymphoedema in Mice.

Gousopoulos E, Karaman S, Proulx ST, Leu K, Buschle D, Detmar M.

Eur Surg Res. 2017;58(3-4):180-192. doi: 10.1159/000461579. Epub 2017 Mar 17.


Evaluation of Encephaloduroarteriosynangiosis Efficacy Using Probabilistic Independent Component Analysis Applied to Dynamic Susceptibility Contrast Perfusion MRI.

Laiwalla AN, Kurth F, Leu K, Liou R, Pamplona J, Ooi YC, Salamon N, Ellingson BM, Gonzalez NR.

AJNR Am J Neuroradiol. 2017 Mar;38(3):507-514. doi: 10.3174/ajnr.A5041. Epub 2017 Jan 19.


Phase 2 study of dasatinib in patients with alveolar soft part sarcoma, chondrosarcoma, chordoma, epithelioid sarcoma, or solitary fibrous tumor.

Schuetze SM, Bolejack V, Choy E, Ganjoo KN, Staddon AP, Chow WA, Tawbi HA, Samuels BL, Patel SR, von Mehren M, D'Amato G, Leu KM, Loeb DM, Forscher CA, Milhem MM, Rushing DA, Lucas DR, Chugh R, Reinke DK, Baker LH.

Cancer. 2017 Jan 1;123(1):90-97. doi: 10.1002/cncr.30379. Epub 2016 Oct 3.


Baseline pretreatment contrast enhancing tumor volume including central necrosis is a prognostic factor in recurrent glioblastoma: evidence from single and multicenter trials.

Ellingson BM, Harris RJ, Woodworth DC, Leu K, Zaw O, Mason WP, Sahebjam S, Abrey LE, Aftab DT, Schwab GM, Hessel C, Lai A, Nghiemphu PL, Pope WB, Wen PY, Cloughesy TF.

Neuro Oncol. 2017 Jan;19(1):89-98. doi: 10.1093/neuonc/now187. Epub 2016 Aug 31.


Distinct role of Arabidopsis mitochondrial P-type pentatricopeptide repeat protein-modulating editing protein, PPME, in nad1 RNA editing.

Leu KC, Hsieh MH, Wang HJ, Hsieh HL, Jauh GY.

RNA Biol. 2016 Jun 2;13(6):593-604. doi: 10.1080/15476286.2016.1184384. Epub 2016 May 5.


Improved Leakage Correction for Single-Echo Dynamic Susceptibility Contrast Perfusion MRI Estimates of Relative Cerebral Blood Volume in High-Grade Gliomas by Accounting for Bidirectional Contrast Agent Exchange.

Leu K, Boxerman JL, Cloughesy TF, Lai A, Nghiemphu PL, Liau LM, Pope WB, Ellingson BM.

AJNR Am J Neuroradiol. 2016 Aug;37(8):1440-6. doi: 10.3174/ajnr.A4759. Epub 2016 Apr 14.


Bidirectional Contrast agent leakage correction of dynamic susceptibility contrast (DSC)-MRI improves cerebral blood volume estimation and survival prediction in recurrent glioblastoma treated with bevacizumab.

Leu K, Boxerman JL, Lai A, Nghiemphu PL, Pope WB, Cloughesy TF, Ellingson BM.

J Magn Reson Imaging. 2016 Nov;44(5):1229-1237. doi: 10.1002/jmri.25227. Epub 2016 Mar 12.


Diffusion MR Characteristics Following Concurrent Radiochemotherapy Predicts Progression-Free and Overall Survival in Newly Diagnosed Glioblastoma.

Chang W, Pope WB, Harris RJ, Hardy AJ, Leu K, Mody RR, Nghiemphu PL, Lai A, Cloughesy TF, Ellingson BM.

Tomography. 2015 Sep;1(1):37-43.


Association between lesion location and language function in adult glioma using voxel-based lesion-symptom mapping.

Banerjee P, Leu K, Harris RJ, Cloughesy TF, Lai A, Nghiemphu PL, Pope WB, Bookheimer SY, Ellingson BM.

Neuroimage Clin. 2015 Oct 23;9:617-24. doi: 10.1016/j.nicl.2015.10.010. eCollection 2015.


Topographical Distribution of Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex.

Ellingson BM, Hirata Y, Yogi A, Karavaeva E, Leu K, Woodworth DC, Harris RJ, Enzmann DR, Wu JY, Mathern GW, Salamon N.

J Child Neurol. 2016 Apr;31(5):636-45. doi: 10.1177/0883073815609151. Epub 2015 Oct 15.


Unique Microstructural Changes in the Brain Associated with Urological Chronic Pelvic Pain Syndrome (UCPPS) Revealed by Diffusion Tensor MRI, Super-Resolution Track Density Imaging, and Statistical Parameter Mapping: A MAPP Network Neuroimaging Study.

Woodworth D, Mayer E, Leu K, Ashe-McNalley C, Naliboff BD, Labus JS, Tillisch K, Kutch JJ, Farmer MA, Apkarian AV, Johnson KA, Mackey SC, Ness TJ, Landis JR, Deutsch G, Harris RE, Clauw DJ, Mullins C, Ellingson BM; MAPP Research Network.

PLoS One. 2015 Oct 13;10(10):e0140250. doi: 10.1371/journal.pone.0140250. eCollection 2015.


Effects of cost metric on cost-effectiveness of protected-area network design in urban landscapes.

Burkhalter JC, Lockwood JL, Maslo B, Fenn KH, Leu K.

Conserv Biol. 2016 Apr;30(2):403-12. doi: 10.1111/cobi.12625. Epub 2015 Dec 11.


Quantitative multiparametric MRI in uveal melanoma: increased tumor permeability may predict monosomy 3.

Kamrava M, Sepahdari AR, Leu K, Wang PC, Roberts K, Demanes DJ, McCannel T, Ellingson BM.

Neuroradiology. 2015 Aug;57(8):833-40. doi: 10.1007/s00234-015-1546-0. Epub 2015 May 29.


RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development.

Verma R, Su S, McCrann DJ, Green JM, Leu K, Young PR, Schatz PJ, Silva JC, Stokes MP, Wojchowski DM.

J Exp Med. 2015 Jun 1;212(6):971. doi: 10.1084/jem.2013062404242015c. Epub 2015 May 4. No abstract available.


Hypervascular tumor volume estimated by comparison to a large-scale cerebral blood volume radiographic atlas predicts survival in recurrent glioblastoma treated with bevacizumab.

Leu K, Enzmann DR, Woodworth DC, Harris RJ, Tran AN, Lai A, Nghiemphu PL, Pope WB, Cloughesy TF, Ellingson BM.

Cancer Imaging. 2014 Nov 14;14:31. doi: 10.1186/s40644-014-0031-z.


Relationship Between [18F]FDOPA PET Uptake, Apparent Diffusion Coefficient (ADC), and Proliferation Rate in Recurrent Malignant Gliomas.

Karavaeva E, Harris RJ, Leu K, Shabihkhani M, Yong WH, Pope WB, Lai A, Nghiemphu PL, Liau LM, Chen W, Czernin J, Cloughesy TF, Ellingson BM.

Mol Imaging Biol. 2015 Jun;17(3):434-42. doi: 10.1007/s11307-014-0807-3.


Pediatric asthma and the use of metered dose inhalers with valve holding chambers: barriers to the implementation of evidence-based practice.

Mudd SS, Leu K, Sloand ED, Ngo TL.

J Emerg Nurs. 2015 Jan;41(1):13-8. doi: 10.1016/j.jen.2014.06.009. Epub 2014 Sep 12. Review. No abstract available.


RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development.

Verma R, Su S, McCrann DJ, Green JM, Leu K, Young PR, Schatz PJ, Silva JC, Stokes MP, Wojchowski DM.

J Exp Med. 2014 Aug 25;211(9):1715-22. doi: 10.1084/jem.20130624. Epub 2014 Aug 4. Erratum in: J Exp Med. 2015 Jun 1;212(6):971.


Imaging biomarkers for antiangiogenic therapy in malignant gliomas.

Leu K, Pope WB, Cloughesy TF, Lai A, Nghiemphu PL, Chen W, Liau LM, Ellingson BM.

CNS Oncol. 2013 Jan;2(1):33-47. Review.


Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences.

Leu K, Kervio E, Obermayer B, Turk-MacLeod RM, Yuan C, Luevano JM Jr, Chen E, Gerland U, Richert C, Chen IA.

J Am Chem Soc. 2013 Jan 9;135(1):354-66. doi: 10.1021/ja3095558. Epub 2012 Dec 21.


Peginesatide and erythropoietin stimulate similar erythropoietin receptor-mediated signal transduction and gene induction events.

Green JM, Leu K, Worth A, Mortensen RB, Martinez DK, Schatz PJ, Wojchowski DM, Young PR.

Exp Hematol. 2012 Jul;40(7):575-87. doi: 10.1016/j.exphem.2012.02.007. Epub 2012 Mar 6. Erratum in: Exp Hematol. 2014 Sep;42(9):838.


Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences.

Derr J, Manapat ML, Rajamani S, Leu K, Xulvi-Brunet R, Joseph I, Nowak MA, Chen IA.

Nucleic Acids Res. 2012 May;40(10):4711-22. doi: 10.1093/nar/gks065. Epub 2012 Feb 7.


Dynamic ligand modulation of EPO receptor pools, and dysregulation by polycythemia-associated EPOR alleles.

Singh S, Verma R, Pradeep A, Leu K, Mortensen RB, Young PR, Oyasu M, Schatz PJ, Green JM, Wojchowski DM.

PLoS One. 2012;7(1):e29064. doi: 10.1371/journal.pone.0029064. Epub 2012 Jan 12.


The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA.

Leu K, Obermayer B, Rajamani S, Gerland U, Chen IA.

Nucleic Acids Res. 2011 Oct;39(18):8135-47. doi: 10.1093/nar/gkr525. Epub 2011 Jun 30.


Attenuation of circulatory shock and cerebral ischemia injury in heat stroke by combination treatment with dexamethasone and hydroxyethyl starch.

Yang TH, Shih MF, Wen YS, Ho WY, Leu KL, Wang MY, Liu CC.

Exp Transl Stroke Med. 2010 Oct 11;2(1):19. doi: 10.1186/2040-7378-2-19.


Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication.

Rajamani S, Ichida JK, Antal T, Treco DA, Leu K, Nowak MA, Szostak JW, Chen IA.

J Am Chem Soc. 2010 Apr 28;132(16):5880-5. doi: 10.1021/ja100780p.


Effects of S-adenosylhomocysteine and homocysteine on DNA damage and cell cytotoxicity in murine hepatic and microglia cell lines.

Liu CC, Ho WY, Leu KL, Tsai HM, Yang TH.

J Biochem Mol Toxicol. 2009 Sep-Oct;23(5):349-56. doi: 10.1002/jbt.20298.


Discovery and optimization of a TRAIL R2 agonist for cancer therapy.

Angell YM, Bhandari A, De Francisco MN, Frederick BT, Green JM, Leu K, Leuther K, Sana R, Schatz PJ, Whitehorn EA, Wright K, Holmes CP.

Adv Exp Med Biol. 2009;611:101-3. No abstract available.


The impact of palliative care on cancer deaths in Hong Kong: a retrospective study of 494 cancer deaths.

Tse DM, Chan KS, Lam WM, Leu K, Lam PT.

Palliat Med. 2007 Jul;21(5):425-33.


Assessment of ifosfamide pharmacokinetics, toxicity, and relation to CYP3A4 activity as measured by the erythromycin breath test in patients with sarcoma.

Chugh R, Wagner T, Griffith KA, Taylor JM, Thomas DG, Worden FP, Leu KM, Zalupski MM, Baker LH.

Cancer. 2007 Jun 1;109(11):2315-22.


Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia.

Fan Q, Leuther KK, Holmes CP, Fong KL, Zhang J, Velkovska S, Chen MJ, Mortensen RB, Leu K, Green JM, Schatz PJ, Woodburn KW.

Exp Hematol. 2006 Oct;34(10):1303-11.


Phase II study of 9-nitro-camptothecin in patients with advanced chordoma or soft tissue sarcoma.

Chugh R, Dunn R, Zalupski MM, Biermann JS, Sondak VK, Mace JR, Leu KM, Chandler WF, Baker LH.

J Clin Oncol. 2005 May 20;23(15):3597-604.


Randomized phase II evaluation of 6 g/m2 of ifosfamide plus doxorubicin and granulocyte colony-stimulating factor (G-CSF) compared with 12 g/m2 of ifosfamide plus doxorubicin and G-CSF in the treatment of poor-prognosis soft tissue sarcoma.

Worden FP, Taylor JM, Biermann JS, Sondak VK, Leu KM, Chugh R, McGinn CJ, Zalupski MM, Baker LH.

J Clin Oncol. 2005 Jan 1;23(1):105-12. Erratum in: J Clin Oncol. 2014 Jan 1;32(1):63. Dosage error in article text. J Clin Oncol. 2006 Sep 1;24(25):4223.


Laboratory and clinical evidence of synergistic cytotoxicity of sequential treatment with gemcitabine followed by docetaxel in the treatment of sarcoma.

Leu KM, Ostruszka LJ, Shewach D, Zalupski M, Sondak V, Biermann JS, Lee JS, Couwlier C, Palazzolo K, Baker LH.

J Clin Oncol. 2004 May 1;22(9):1706-12.


Cytochrome P450 CYP3A4/5 expression as a biomarker of outcome in osteosarcoma.

Dhaini HR, Thomas DG, Giordano TJ, Johnson TD, Biermann JS, Leu K, Hollenberg PF, Baker LH.

J Clin Oncol. 2003 Jul 1;21(13):2481-5.


Images in clinical medicine. Osteoporosis circumscripta.

Leu KM, Kalemkerian GP.

N Engl J Med. 2002 Aug 1;347(5):e2. No abstract available.


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