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Items: 1 to 50 of 56

1.

Efficacy and Safety of Intravenous Golimumab through 1 Year in Patients with Active Psoriatic Arthritis.

Husni ME, Kavanaugh A, Murphy F, Rekalov D, Harrison DD, Kim L, Lo KH, Leu JH, Hsia EC.

Arthritis Care Res (Hoboken). 2019 Apr 12. doi: 10.1002/acr.23905. [Epub ahead of print]

PMID:
30980514
2.

Identification and expression analysis of 19 CC chemokine genes in orange-spotted grouper (Epinephelus coioides).

Leu JH, Tsai CH, Tsai JM, Yang CH, Hsueh CY, Chou HY.

Dev Comp Immunol. 2019 Aug;97:1-10. doi: 10.1016/j.dci.2019.03.006. Epub 2019 Mar 20.

PMID:
30904428
3.

Safety and Efficacy of Intravenous Golimumab in Adults with Ankylosing Spondylitis: Results through 1 Year of the GO-ALIVE Study.

Reveille JD, Deodhar A, Caldron PH, Dudek A, Harrison DD, Kim L, Lo KH, Leu JH, Hsia EC.

J Rheumatol. 2019 Oct;46(10):1277-1283. doi: 10.3899/jrheum.180718. Epub 2019 Mar 1.

4.

Immunogenicity of Golimumab and its Clinical Relevance in Patients With Ulcerative Colitis.

Adedokun OJ, Gunn GR, Leu JH, Gargano C, Xu Z, Sandborn WJ, Rutgeerts P, Shankar G.

Inflamm Bowel Dis. 2019 Aug 20;25(9):1532-1540. doi: 10.1093/ibd/izz003.

PMID:
30753466
5.

Immunogenicity of golimumab and its clinical relevance in patients with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.

Leu JH, Adedokun OJ, Gargano C, Hsia EC, Xu Z, Shankar G.

Rheumatology (Oxford). 2019 Mar 1;58(3):441-446. doi: 10.1093/rheumatology/key309.

PMID:
30412238
6.

Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis.

Deodhar A, Gensler LS, Sieper J, Clark M, Calderon C, Wang Y, Zhou Y, Leu JH, Campbell K, Sweet K, Harrison DD, Hsia EC, van der Heijde D.

Arthritis Rheumatol. 2019 Feb;71(2):258-270. doi: 10.1002/art.40728. Epub 2018 Dec 29.

PMID:
30225992
7.

Safety and Efficacy of Golimumab Administered Intravenously in Adults with Ankylosing Spondylitis: Results through Week 28 of the GO-ALIVE Study.

Deodhar A, Reveille JD, Harrison DD, Kim L, Lo KH, Leu JH, Hsia EC.

J Rheumatol. 2018 Mar;45(3):341-348. doi: 10.3899/jrheum.170487. Epub 2017 Dec 15. Erratum in: J Rheumatol. 2018 Feb;45(2):291.

8.

Safety and Efficacy of Intravenous Golimumab in Patients With Active Psoriatic Arthritis: Results Through Week Twenty-Four of the GO-VIBRANT Study.

Kavanaugh A, Husni ME, Harrison DD, Kim L, Lo KH, Leu JH, Hsia EC.

Arthritis Rheumatol. 2017 Nov;69(11):2151-2161. doi: 10.1002/art.40226.

9.

Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial.

Brunner HI, Ruperto N, Tzaribachev N, Horneff G, Chasnyk VG, Panaviene V, Abud-Mendoza C, Reiff A, Alexeeva E, Rubio-Pérez N, Keltsev V, Kingsbury DJ, Del Rocio Maldonado Velázquez M, Nikishina I, Silverman ED, Joos R, Smolewska E, Bandeira M, Minden K, van Royen-Kerkhof A, Emminger W, Foeldvari I, Lauwerys BR, Sztajnbok F, Gilmer KE, Xu Z, Leu JH, Kim L, Lamberth SL, Loza MJ, Lovell DJ, Martini A; Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).

Ann Rheum Dis. 2018 Jan;77(1):21-29. doi: 10.1136/annrheumdis-2016-210456. Epub 2017 May 15.

10.

Safety and Efficacy of Subcutaneous Golimumab in Patients with Active Rheumatoid Arthritis despite Methotrexate Therapy: Final 5-year Results of the GO-FORWARD Trial.

Keystone EC, Genovese MC, Hall S, Bae SC, Han C, Gathany TA, Xu S, Zhou Y, Leu JH, Hsia EC.

J Rheumatol. 2016 Feb;43(2):298-306. doi: 10.3899/jrheum.150712. Epub 2015 Dec 15.

PMID:
26669912
11.
12.

Efficacy and Safety of Subcutaneous Golimumab in Methotrexate-Naive Patients With Rheumatoid Arthritis: Five-Year Results of a Randomized Clinical Trial.

Emery P, Fleischmann RM, Strusberg I, Durez P, Nash P, Amante EJ, Churchill M, Park W, Pons-Estel B, Han C, Gathany TA, Xu S, Zhou Y, Leu JH, Hsia EC.

Arthritis Care Res (Hoboken). 2016 Jun;68(6):744-52. doi: 10.1002/acr.22759.

13.

The novel white spot syndrome virus-induced gene, PmERP15, encodes an ER stress-responsive protein in black tiger shrimp, Penaeus monodon.

Leu JH, Liu KF, Chen KY, Chen SH, Wang YB, Lin CY, Lo CF.

Dev Comp Immunol. 2015 Apr;49(2):239-48. doi: 10.1016/j.dci.2014.12.001. Epub 2014 Dec 11.

PMID:
25499032
14.

The promoter of the white spot syndrome virus immediate-early gene WSSV108 is activated by the cellular KLF transcription factor.

Liu WJ, Lo CF, Kou GH, Leu JH, Lai YJ, Chang LK, Chang YS.

Dev Comp Immunol. 2015 Mar;49(1):7-18. doi: 10.1016/j.dci.2014.10.015. Epub 2014 Nov 6.

PMID:
25445906
15.

The genome and occlusion bodies of marine Penaeus monodon nudivirus (PmNV, also known as MBV and PemoNPV) suggest that it should be assigned to a new nudivirus genus that is distinct from the terrestrial nudiviruses.

Yang YT, Lee DY, Wang Y, Hu JM, Li WH, Leu JH, Chang GD, Ke HM, Kang ST, Lin SS, Kou GH, Lo CF.

BMC Genomics. 2014 Jul 25;15:628. doi: 10.1186/1471-2164-15-628.

16.

A newly identified protein complex that mediates white spot syndrome virus infection via chitin-binding protein.

Huang PY, Leu JH, Chen LL.

J Gen Virol. 2014 Aug;95(Pt 8):1799-808. doi: 10.1099/vir.0.064782-0. Epub 2014 May 16.

PMID:
24836670
17.

Clinical efficacy, radiographic and safety findings through 5 years of subcutaneous golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of a randomised, placebo-controlled trial (the GO-REVEAL study).

Kavanaugh A, McInnes IB, Mease P, Krueger GG, Gladman D, van der Heijde D, Zhou Y, Lu J, Leu JH, Goldstein N, Beutler A.

Ann Rheum Dis. 2014 Sep;73(9):1689-94. doi: 10.1136/annrheumdis-2013-204902. Epub 2014 Apr 19.

18.

Characterization and interactome study of white spot syndrome virus envelope protein VP11.

Liu WJ, Shiung HJ, Lo CF, Leu JH, Lai YJ, Lee TL, Huang WT, Kou GH, Chang YS.

PLoS One. 2014 Jan 21;9(1):e85779. doi: 10.1371/journal.pone.0085779. eCollection 2014.

19.

Endocytic pathway is indicated for white spot syndrome virus (WSSV) entry in shrimp.

Huang ZJ, Kang ST, Leu JH, Chen LL.

Fish Shellfish Immunol. 2013 Sep;35(3):707-15. doi: 10.1016/j.fsi.2013.05.028. Epub 2013 Jun 6.

PMID:
23747417
20.

A model for apoptotic interaction between white spot syndrome virus and shrimp.

Leu JH, Lin SJ, Huang JY, Chen TC, Lo CF.

Fish Shellfish Immunol. 2013 Apr;34(4):1011-7. doi: 10.1016/j.fsi.2012.05.030. Epub 2012 Jun 7. Review.

PMID:
22683516
21.

Litopenaeus vannamei inhibitor of apoptosis protein 1 (LvIAP1) is essential for shrimp survival.

Leu JH, Chen YC, Chen LL, Chen KY, Huang HT, Ho JM, Lo CF.

Dev Comp Immunol. 2012 Sep;38(1):78-87. doi: 10.1016/j.dci.2012.04.006. Epub 2012 May 5.

PMID:
22564858
22.

A putative cell surface receptor for white spot syndrome virus is a member of a transporter superfamily.

Huang HT, Leu JH, Huang PY, Chen LL.

PLoS One. 2012;7(3):e33216. doi: 10.1371/journal.pone.0033216. Epub 2012 Mar 13.

23.

Penaeus monodon thioredoxin restores the DNA binding activity of oxidized white spot syndrome virus IE1.

Huang JY, Liu WJ, Wang HC, Lee DY, Leu JH, Wang HC, Tsai MH, Kang ST, Chen IT, Kou GH, Chang GD, Lo CF.

Antioxid Redox Signal. 2012 Sep 15;17(6):914-26. doi: 10.1089/ars.2011.4264. Epub 2012 Apr 16.

24.

The role of aldehyde dehydrogenase and hsp70 in suppression of white spot syndrome virus replication at high temperature.

Lin YR, Hung HC, Leu JH, Wang HC, Kou GH, Lo CF.

J Virol. 2011 Apr;85(7):3517-25. doi: 10.1128/JVI.01973-10. Epub 2011 Jan 12.

25.

Differential expression of LvHSP60 in shrimp in response to environmental stress.

Huang WJ, Leu JH, Tsau MT, Chen JC, Chen LL.

Fish Shellfish Immunol. 2011 Feb;30(2):576-82. doi: 10.1016/j.fsi.2010.12.001. Epub 2010 Dec 21.

PMID:
21182965
26.

Shrimp Pm-fortilin inhibits the expression of early and late genes of white spot syndrome virus (WSSV) in an insect cell model.

Nupan B, Phongdara A, Saengsakda M, Leu JH, Lo CF.

Dev Comp Immunol. 2011 Apr;35(4):469-75. doi: 10.1016/j.dci.2010.11.016. Epub 2010 Dec 3.

PMID:
21130805
27.

Label free detection of white spot syndrome virus using lead magnesium niobate-lead titanate piezoelectric microcantilever sensors.

Capobianco JA, Shih WH, Leu JH, Lo GC, Shih WY.

Biosens Bioelectron. 2010 Nov 15;26(3):964-9. doi: 10.1016/j.bios.2010.08.004. Epub 2010 Aug 11.

28.

Molecular mechanism of the interactions between white spot syndrome virus anti-apoptosis protein AAP-1 (WSSV449) and shrimp effector caspase.

Leu JH, Chen LL, Lin YR, Kou GH, Lo CF.

Dev Comp Immunol. 2010 Oct;34(10):1068-74. doi: 10.1016/j.dci.2010.05.010. Epub 2010 May 28.

PMID:
20546774
29.

A review of the major penaeid shrimp EST studies and the construction of a shrimp transcriptome database based on the ESTs from four penaeid shrimp.

Leu JH, Chen SH, Wang YB, Chen YC, Su SY, Lin CY, Ho JM, Lo CF.

Mar Biotechnol (NY). 2011 Aug;13(4):608-21. doi: 10.1007/s10126-010-9286-y. Epub 2010 Apr 17. Review.

PMID:
20401624
30.

Polycistronic mRNAs and internal ribosome entry site elements (IRES) are widely used by white spot syndrome virus (WSSV) structural protein genes.

Kang ST, Leu JH, Wang HC, Chen LL, Kou GH, Lo CF.

Virology. 2009 May 10;387(2):353-63. doi: 10.1016/j.virol.2009.02.012. Epub 2009 Mar 14.

31.

Whispovirus.

Leu JH, Yang F, Zhang X, Xu X, Kou GH, Lo CF.

Curr Top Microbiol Immunol. 2009;328:197-227. Review.

PMID:
19216439
32.

White spot syndrome virus protein ICP11: A histone-binding DNA mimic that disrupts nucleosome assembly.

Wang HC, Wang HC, Ko TP, Lee YM, Leu JH, Ho CH, Huang WP, Lo CF, Wang AH.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20758-63. doi: 10.1073/pnas.0811233106. Epub 2008 Dec 18.

33.

Transactivation, dimerization, and DNA-binding activity of white spot syndrome virus immediate-early protein IE1.

Liu WJ, Chang YS, Wang HC, Leu JH, Kou GH, Lo CF.

J Virol. 2008 Nov;82(22):11362-73. doi: 10.1128/JVI.01244-08. Epub 2008 Sep 3.

34.

WSSV infection activates STAT in shrimp.

Chen WY, Ho KC, Leu JH, Liu KF, Wang HC, Kou GH, Lo CF.

Dev Comp Immunol. 2008;32(10):1142-50. doi: 10.1016/j.dci.2008.03.003. Epub 2008 Apr 7.

PMID:
18460415
35.

Penaeus monodon caspase is targeted by a white spot syndrome virus anti-apoptosis protein.

Leu JH, Wang HC, Kou GH, Lo CF.

Dev Comp Immunol. 2008;32(5):476-86. Epub 2007 Sep 7.

PMID:
17905432
36.

Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.

Menon RM, Adams MH, González MA, Tolbert DS, Leu JH, Cefali EA.

Int J Clin Pharmacol Ther. 2007 Aug;45(8):448-54.

PMID:
17725178
37.

Molecular cloning and characterization of an inhibitor of apoptosis protein (IAP) from the tiger shrimp, Penaeus monodon.

Leu JH, Kuo YC, Kou GH, Lo CF.

Dev Comp Immunol. 2008;32(2):121-33. Epub 2007 Jun 14.

PMID:
17628672
38.

Comparative analysis of differentially expressed genes in normal and white spot syndrome virus infected Penaeus monodon.

Leu JH, Chang CC, Wu JL, Hsu CW, Hirono I, Aoki T, Juan HF, Lo CF, Kou GH, Huang HC.

BMC Genomics. 2007 May 16;8:120.

39.

Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites.

Menon RM, González MA, Adams MH, Tolbert DS, Leu JH, Cefali EA.

J Clin Pharmacol. 2007 Jun;47(6):681-8. Epub 2007 Apr 26.

PMID:
17463214
40.

Protein expression profiling of the shrimp cellular response to white spot syndrome virus infection.

Wang HC, Wang HC, Leu JH, Kou GH, Wang AH, Lo CF.

Dev Comp Immunol. 2007;31(7):672-86. Epub 2006 Dec 5.

PMID:
17188354
41.

Identification of the nucleocapsid, tegument, and envelope proteins of the shrimp white spot syndrome virus virion.

Tsai JM, Wang HC, Leu JH, Wang AH, Zhuang Y, Walker PJ, Kou GH, Lo CF.

J Virol. 2006 Mar;80(6):3021-9.

43.

Genomic and proteomic analysis of thirty-nine structural proteins of shrimp white spot syndrome virus.

Tsai JM, Wang HC, Leu JH, Hsiao HH, Wang AH, Kou GH, Lo CF.

J Virol. 2004 Oct;78(20):11360-70.

44.
45.

Genomic structure, expression and characterization of a STAT5 homologue from pufferfish (Tetraodon fluviatilis).

Sung SC, Fan TJ, Chou CM, Leu JH, Hsu YL, Chen ST, Hsieh YC, Huang CJ.

Eur J Biochem. 2003 Jan;270(2):239-52.

47.

Genomic organization and the promoter region of the round-spotted pufferfish (Tetraodon fluviatilis) CDC37 gene.

Tsai SC, Leu JH, Chou CM, Yeh MS, Huang FL, Huang CJ.

Biochim Biophys Acta. 2000 Nov 15;1494(1-2):144-8.

PMID:
11072077
48.
49.

Complete genomic organization and promoter analysis of the round-spotted pufferfish JAK1, JAK2, JAK3, and TYK2 genes.

Leu JH, Yan SJ, Lee TF, Chou CM, Chen ST, Hwang PP, Chou CK, Huang CJ.

DNA Cell Biol. 2000 Jul;19(7):431-46.

PMID:
10945233
50.

Molecular cloning and characterization of a hemolymph clottable protein from tiger shrimp (Penaeus monodon).

Yeh MS, Huang CJ, Leu JH, Lee YC, Tsai IH.

Eur J Biochem. 1999 Dec;266(2):624-33.

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