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Comparison of cofilin‑1 and Twist‑1 protein expression in human non‑small cell lung cancer tissues.

Chang CY, Chang SL, Leu JD, Chang YC, Hsiao M, Lin LT, Lin HN, Lee YJ.

Oncol Rep. 2019 Jun 10. doi: 10.3892/or.2019.7193. [Epub ahead of print]


Efficacy and Safety of Intravenous Golimumab through 1 Year in Patients with Active Psoriatic Arthritis.

Husni ME, Kavanaugh A, Murphy F, Rekalov D, Harrison DD, Kim L, Lo KH, Leu JH, Hsia EC.

Arthritis Care Res (Hoboken). 2019 Apr 12. doi: 10.1002/acr.23905. [Epub ahead of print]


Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53.

Leu JI, Murphy ME, George DL.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8390-8396. doi: 10.1073/pnas.1821277116. Epub 2019 Apr 8.


Identification and expression analysis of 19 CC chemokine genes in orange-spotted grouper (Epinephelus coioides).

Leu JH, Tsai CH, Tsai JM, Yang CH, Hsueh CY, Chou HY.

Dev Comp Immunol. 2019 Aug;97:1-10. doi: 10.1016/j.dci.2019.03.006. Epub 2019 Mar 20.


Safety and Efficacy of Intravenous Golimumab in Adults with Ankylosing Spondylitis: Results through 1 Year of the GO-ALIVE Study.

Reveille JD, Deodhar A, Caldron PH, Dudek A, Harrison DD, Kim L, Lo KH, Leu JH, Hsia EC.

J Rheumatol. 2019 Mar 1. pii: jrheum.180718. doi: 10.3899/jrheum.180718. [Epub ahead of print]


Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform.

Moraes CB, Witt G, Kuzikov M, Ellinger B, Calogeropoulou T, Prousis KC, Mangani S, Di Pisa F, Landi G, Iacono LD, Pozzi C, Freitas-Junior LH, Dos Santos Pascoalino B, Bertolacini CP, Behrens B, Keminer O, Leu J, Wolf M, Reinshagen J, Cordeiro-da-Silva A, Santarem N, Venturelli A, Wrigley S, Karunakaran D, Kebede B, Pöhner I, Müller W, Panecka-Hofman J, Wade RC, Fenske M, Clos J, Alunda JM, Corral MJ, Uliassi E, Bolognesi ML, Linciano P, Quotadamo A, Ferrari S, Santucci M, Borsari C, Costi MP, Gul S.

SLAS Discov. 2019 Mar;24(3):346-361. doi: 10.1177/2472555218823171.


Immunogenicity of Golimumab and its Clinical Relevance in Patients With Ulcerative Colitis.

Adedokun OJ, Gunn GR 3rd, Leu JH, Gargano C, Xu Z, Sandborn WJ, Rutgeerts P, Shankar G.

Inflamm Bowel Dis. 2019 Feb 8. doi: 10.1093/ibd/izz003. [Epub ahead of print]


Higher Intra-Dialysis Serum Phosphorus Reduction Ratio as a Predictor of Mortality in Patients on Long-Term Hemodialysis.

Fang YW, Leu JG, Tsai MH, Liou HH.

Med Sci Monit. 2019 Jan 24;25:691-699. doi: 10.12659/MSM.913137.


Modified Sijunzi decoction can alleviate cisplatin-induced toxicity and prolong the survival time of cachectic mice by recovering muscle atrophy.

Chen JM, Yang TT, Cheng TS, Hsiao TF, Chang PM, Leu JY, Wang FS, Hsu SL, Huang CF, Lai JM.

J Ethnopharmacol. 2019 Apr 6;233:47-55. doi: 10.1016/j.jep.2018.12.035. Epub 2018 Dec 24.


Enhanced Photocatalytic Performance of Nitrogen-Doped TiO₂ Nanotube Arrays Using a Simple Annealing Process.

Le PH, Hieu LT, Lam TN, Hang NTN, Truong NV, Tuyen LTC, Phong PT, Leu J.

Micromachines (Basel). 2018 Nov 24;9(12). pii: E618. doi: 10.3390/mi9120618.


Heterologous Hsp90 promotes phenotypic diversity through network evolution.

Koubkova-Yu TC, Chao JC, Leu JY.

PLoS Biol. 2018 Nov 15;16(11):e2006450. doi: 10.1371/journal.pbio.2006450. eCollection 2018 Nov.


Association of Serum Aluminum Levels with Mortality in Patients on Chronic Hemodialysis.

Tsai MH, Fang YW, Liou HH, Leu JG, Lin BS.

Sci Rep. 2018 Nov 13;8(1):16729. doi: 10.1038/s41598-018-34799-5.


Immunogenicity of golimumab and its clinical relevance in patients with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.

Leu JH, Adedokun OJ, Gargano C, Hsia EC, Xu Z, Shankar G.

Rheumatology (Oxford). 2019 Mar 1;58(3):441-446. doi: 10.1093/rheumatology/key309.


Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis.

Deodhar A, Gensler LS, Sieper J, Clark M, Calderon C, Wang Y, Zhou Y, Leu JH, Campbell K, Sweet K, Harrison DD, Hsia EC, van der Heijde D.

Arthritis Rheumatol. 2019 Feb;71(2):258-270. doi: 10.1002/art.40728. Epub 2018 Dec 29.


Tailoring Chemotherapy for the African-Centric S47 Variant of TP53.

Barnoud T, Budina-Kolomets A, Basu S, Leu JI, Good M, Kung CP, Liu J, Liu Q, Villanueva J, Zhang R, George DL, Murphy ME.

Cancer Res. 2018 Oct 1;78(19):5694-5705. doi: 10.1158/0008-5472.CAN-18-1327. Epub 2018 Aug 16.


Misfolding-prone proteins are reversibly sequestered to an Hsp42-associated granule upon chronological aging.

Lee HY, Chao JC, Cheng KY, Leu JY.

J Cell Sci. 2018 Aug 20;131(16). pii: jcs220202. doi: 10.1242/jcs.220202.


Methylation of RNA N6-methyladenosine in modulation of cytokine responses and tumorigenesis.

Chang G, Leu JS, Ma L, Xie K, Huang S.

Cytokine. 2019 Jun;118:35-41. doi: 10.1016/j.cyto.2018.06.018. Epub 2018 Jul 13. Review.


Synergistic effects of tetrandrine combined with ionizing radiation on a murine colorectal carcinoma‑bearing mouse model.

Lin WC, Wang WH, Lin YH, Leu JD, Cheng SY, Chen YJ, Hwang JJ.

Oncol Rep. 2018 Sep;40(3):1390-1400. doi: 10.3892/or.2018.6568. Epub 2018 Jul 12.


An atypical presentation of high potassium renal secretion rate in a patient with thyrotoxic periodic paralysis: a case report.

Tu ML, Fang YW, Leu JG, Tsai MH.

BMC Nephrol. 2018 Jul 4;19(1):160. doi: 10.1186/s12882-018-0971-9.


Investigation of the Mechanism of Therapeutic Protein-Drug Interaction Between Methotrexate and Golimumab, an Anti-TNFα Monoclonal Antibody.

Wang W, Leu J, Watson R, Xu Z, Zhou H.

AAPS J. 2018 Apr 17;20(3):63. doi: 10.1208/s12248-018-0219-4.


Arsenic trioxide-mediated suppression of miR-182-5p is associated with potent anti-oxidant effects through up-regulation of SESN2.

Lin LT, Liu SY, Leu JD, Chang CY, Chiou SH, Lee TC, Lee YJ.

Oncotarget. 2018 Mar 23;9(22):16028-16042. doi: 10.18632/oncotarget.24678. eCollection 2018 Mar 23.


Functional domains of SP110 that modulate its transcriptional regulatory function and cellular translocation.

Leu JS, Chang SY, Mu CY, Chen ML, Yan BS.

J Biomed Sci. 2018 Apr 11;25(1):34. doi: 10.1186/s12929-018-0434-4.


COP1/DET1/ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors.

Xie Y, Cao Z, Wong EW, Guan Y, Ma W, Zhang JQ, Walczak EG, Murphy D, Ran L, Sirota I, Wang S, Shukla S, Gao D, Knott SR, Chang K, Leu J, Wongvipat J, Antonescu CR, Hannon G, Chi P, Chen Y.

J Clin Invest. 2018 Apr 2;128(4):1442-1457. doi: 10.1172/JCI94840. Epub 2018 Mar 5.


Association between serum aluminum levels and cardiothoracic ratio in patients on chronic hemodialysis.

Wang TL, Fang YW, Leu JG, Tsai MH.

PLoS One. 2017 Dec 20;12(12):e0190008. doi: 10.1371/journal.pone.0190008. eCollection 2017.


Safety and Efficacy of Golimumab Administered Intravenously in Adults with Ankylosing Spondylitis: Results through Week 28 of the GO-ALIVE Study.

Deodhar A, Reveille JD, Harrison DD, Kim L, Lo KH, Leu JH, Hsia EC.

J Rheumatol. 2018 Mar;45(3):341-348. doi: 10.3899/jrheum.170487. Epub 2017 Dec 15.


Adenine accelerated the diabetic wound healing by PPAR delta and angiogenic regulation.

Leu JG, Chiang MH, Chen CY, Lin JT, Chen HM, Chen YL, Liang YJ.

Eur J Pharmacol. 2018 Jan 5;818:569-577. doi: 10.1016/j.ejphar.2017.11.027. Epub 2017 Nov 21.


Glucagon-like peptide receptor agonists attenuate advanced glycation end products-induced inflammation in rat mesangial cells.

Chang JT, Liang YJ, Hsu CY, Chen CY, Chen PJ, Yang YF, Chen YL, Pei D, Chang JB, Leu JG.

BMC Pharmacol Toxicol. 2017 Oct 24;18(1):67. doi: 10.1186/s40360-017-0172-3.


A Comprehensive Analysis of Transcript-Supported De Novo Genes in Saccharomyces sensu stricto Yeasts.

Lu TC, Leu JY, Lin WC.

Mol Biol Evol. 2017 Nov 1;34(11):2823-2838. doi: 10.1093/molbev/msx210.


Association of vascular access flow with short-term and long-term mortality in chronic haemodialysis patients: a retrospective cohort study.

Wu CK, Wu CL, Lin CH, Leu JG, Kor CT, Tarng DC.

BMJ Open. 2017 Sep 24;7(9):e017035. doi: 10.1136/bmjopen-2017-017035.


Safety and Efficacy of Intravenous Golimumab in Patients With Active Psoriatic Arthritis: Results Through Week Twenty-Four of the GO-VIBRANT Study.

Kavanaugh A, Husni ME, Harrison DD, Kim L, Lo KH, Leu JH, Hsia EC.

Arthritis Rheumatol. 2017 Nov;69(11):2151-2161. doi: 10.1002/art.40226.


Combination of Radiofrequency Ablation and Glycated Chitosan as Treatment on a Syngeneic Breast Tumor Model.

Chiu HY, Leu JD, Chang CY, Lee YJ, Chen WR.

Anticancer Res. 2017 Jun;37(6):2965-2974.


Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial.

Brunner HI, Ruperto N, Tzaribachev N, Horneff G, Chasnyk VG, Panaviene V, Abud-Mendoza C, Reiff A, Alexeeva E, Rubio-Pérez N, Keltsev V, Kingsbury DJ, Del Rocio Maldonado Velázquez M, Nikishina I, Silverman ED, Joos R, Smolewska E, Bandeira M, Minden K, van Royen-Kerkhof A, Emminger W, Foeldvari I, Lauwerys BR, Sztajnbok F, Gilmer KE, Xu Z, Leu JH, Kim L, Lamberth SL, Loza MJ, Lovell DJ, Martini A; Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).

Ann Rheum Dis. 2018 Jan;77(1):21-29. doi: 10.1136/annrheumdis-2016-210456. Epub 2017 May 15.


Inhibition of stress-inducible HSP70 impairs mitochondrial proteostasis and function.

Leu JI, Barnoud T, Zhang G, Tian T, Wei Z, Herlyn M, Murphy ME, George DL.

Oncotarget. 2017 Jul 11;8(28):45656-45669. doi: 10.18632/oncotarget.17321.


Differentiated cytoplasmic granule formation in quiescent and non-quiescent cells upon chronological aging.

Lee HY, Cheng KY, Chao JC, Leu JY.

Microb Cell. 2016 Mar 3;3(3):109-119. doi: 10.15698/mic2016.03.484.


Coevolution with bacteria drives the evolution of aerobic fermentation in Lachancea kluyveri.

Zhou N, Swamy KB, Leu JY, McDonald MJ, Galafassi S, Compagno C, Piškur J.

PLoS One. 2017 Mar 10;12(3):e0173318. doi: 10.1371/journal.pone.0173318. eCollection 2017.


Combining fisetin and ionizing radiation suppresses the growth of mammalian colorectal cancers in xenograft tumor models.

Leu JD, Wang BS, Chiu SJ, Chang CY, Chen CC, Chen FD, Avirmed S, Lee YJ.

Oncol Lett. 2016 Dec;12(6):4975-4982. doi: 10.3892/ol.2016.5345. Epub 2016 Nov 2.


Mitochondrial-nuclear co-evolution leads to hybrid incompatibility through pentatricopeptide repeat proteins.

Jhuang HY, Lee HY, Leu JY.

EMBO Rep. 2017 Jan;18(1):87-101. doi: 10.15252/embr.201643311. Epub 2016 Dec 5.


Association between peripheral arterial occlusive disease and cardiothoracic ratio in patients on chronic hemodialysis.

Liou KY, Liou HH, Fang YW, Leu JG, Tsai MH.

Sci Rep. 2016 Dec 5;6:38458. doi: 10.1038/srep38458.


SP110b Controls Host Immunity and Susceptibility to Tuberculosis.

Leu JS, Chen ML, Chang SY, Yu SL, Lin CW, Wang H, Chen WC, Chang CH, Wang JY, Lee LN, Yu CJ, Kramnik I, Yan BS.

Am J Respir Crit Care Med. 2017 Feb 1;195(3):369-382. doi: 10.1164/rccm.201601-0103OC.


Experimental Evolution Reveals Interplay between Sch9 and Polyploid Stability in Yeast.

Lu YJ, Swamy KB, Leu JY.

PLoS Genet. 2016 Nov 3;12(11):e1006409. doi: 10.1371/journal.pgen.1006409. eCollection 2016 Nov.


Mutation at a distance caused by homopolymeric guanine repeats in Saccharomyces cerevisiae.

McDonald MJ, Yu YH, Guo JF, Chong SY, Kao CF, Leu JY.

Sci Adv. 2016 May 27;2(5):e1501033. doi: 10.1126/sciadv.1501033. eCollection 2016 May.


Hsp90 mediates the crosstalk between galactose metabolism and cell morphology pathways in yeast.

Gopinath RK, Leu JY.

Curr Genet. 2017 Feb;63(1):23-27. doi: 10.1007/s00294-016-0614-2. Epub 2016 May 21. Review.


An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model.

Jennis M, Kung CP, Basu S, Budina-Kolomets A, Leu JI, Khaku S, Scott JP, Cai KQ, Campbell MR, Porter DK, Wang X, Bell DA, Li X, Garlick DS, Liu Q, Hollstein M, George DL, Murphy ME.

Genes Dev. 2016 Apr 15;30(8):918-30. doi: 10.1101/gad.275891.115. Epub 2016 Mar 31.


High Fibroblast Growth Factor 23 Levels Associated With Low Hemoglobin Levels in Patients With Chronic Kidney Disease Stages 3 and 4.

Tsai MH, Leu JG, Fang YW, Liou HH.

Medicine (Baltimore). 2016 Mar;95(11):e3049. doi: 10.1097/MD.0000000000003049.


HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors.

Budina-Kolomets A, Webster MR, Leu JI, Jennis M, Krepler C, Guerrini A, Kossenkov AV, Xu W, Karakousis G, Schuchter L, Amaravadi RK, Wu H, Yin X, Liu Q, Lu Y, Mills GB, Xu X, George DL, Weeraratna AT, Murphy ME.

Cancer Res. 2016 May 1;76(9):2720-30. doi: 10.1158/0008-5472.CAN-15-2137. Epub 2016 Mar 16.


Hsp90 Maintains Proteostasis of the Galactose Utilization Pathway To Prevent Cell Lethality.

Gopinath RK, Leu JY.

Mol Cell Biol. 2016 Apr 15;36(9):1412-24. doi: 10.1128/MCB.01064-15. Print 2016 May.


The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction.

Kung CP, Leu JI, Basu S, Khaku S, Anokye-Danso F, Liu Q, George DL, Ahima RS, Murphy ME.

Cell Rep. 2016 Mar 15;14(10):2413-25. doi: 10.1016/j.celrep.2016.02.037. Epub 2016 Mar 3.


Endothelial Progenitor Cells Predict Long-Term Mortality in Hemodialysis Patients.

Lu CL, Leu JG, Liu WC, Zheng CM, Lin YF, Shyu JF, Wu CC, Lu KC.

Int J Med Sci. 2016 Feb 20;13(3):240-7. doi: 10.7150/ijms.14209. eCollection 2016.

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