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Items: 35

1.

Conventional and Specific-Pathogen Free Rats Respond Differently to Anesthesia and Surgical Trauma.

Letson HL, Morris J, Biros E, Dobson GP.

Sci Rep. 2019 Jun 28;9(1):9399. doi: 10.1038/s41598-019-45871-z.

2.

ALM Fluid Therapy Leads to 72 hr Survival After Hemorrhagic Shock: a Model for Studying Differential Gene Expression and Extending Biological Time.

Letson HL, Morris J, Biros E, Dobson GP.

J Trauma Acute Care Surg. 2019 Jun 24. doi: 10.1097/TA.0000000000002397. [Epub ahead of print]

PMID:
31162330
3.

The role of invasive monitoring in the resuscitation of major burns: a systematic review and meta-analysis.

Davenport LM, Dobson GP, Letson HL.

Int J Burns Trauma. 2019 Apr 15;9(2):28-40. eCollection 2019.

4.

Absence of cytotoxic and inflammatory effects following in vitro exposure of chondrogenically-differentiated human mesenchymal stem cells to adenosine, lidocaine and Mg2+ solution.

McCutchan A, Dobson GP, Stewart N, Letson HL, Grant AL, Jovanovic IA, Hazratwala K, Wilkinson M, McEwen P, Morris J.

J Exp Orthop. 2019 Apr 15;6(1):16. doi: 10.1186/s40634-019-0185-5.

5.

The CNS theory of osteoarthritis: Opportunities beyond the joint.

Morris JL, Letson HL, Gillman R, Hazratwala K, Wilkinson M, McEwen P, Dobson GP.

Semin Arthritis Rheum. 2019 Mar 16. pii: S0049-0172(19)30012-5. doi: 10.1016/j.semarthrit.2019.03.008. [Epub ahead of print] Review.

PMID:
30982553
6.

Specific pathogen-free (SPF) animal status as a variable in biomedical research: Have we come full circle?

Dobson GP, Letson HL, Biros E, Morris J.

EBioMedicine. 2019 Mar;41:42-43. doi: 10.1016/j.ebiom.2019.02.038. Epub 2019 Feb 23. No abstract available.

7.

Response to letter to the editor.

Letson HL, Dobson GP.

J Trauma Acute Care Surg. 2019 Feb;86(2):376. doi: 10.1097/TA.0000000000002107. No abstract available.

PMID:
30376545
8.

Tranexamic acid is associated with selective increase in inflammatory markers following total knee arthroplasty (TKA): a pilot study.

Grant AL, Letson HL, Morris JL, McEwen P, Hazratwala K, Wilkinson M, Dobson GP.

J Orthop Surg Res. 2018 Jun 18;13(1):149. doi: 10.1186/s13018-018-0855-5.

9.

Defining the osteoarthritis patient: back to the future.

Dobson GP, Letson HL, Grant A, McEwen P, Hazratwala K, Wilkinson M, Morris JL.

Osteoarthritis Cartilage. 2018 Aug;26(8):1003-1007. doi: 10.1016/j.joca.2018.04.018. Epub 2018 May 25. Review.

PMID:
29775734
10.
11.

Adenosine, lidocaine, and Mg2+ (ALM) resuscitation fluid protects against experimental traumatic brain injury.

Letson HL, Dobson GP.

J Trauma Acute Care Surg. 2018 Jun;84(6):908-916. doi: 10.1097/TA.0000000000001874.

PMID:
29554045
12.

Clinical relevance of a p value: Does tranexamic acid save lives after trauma or postpartum hemorrhage?

Dobson GP, Doma K, Letson HL.

J Trauma Acute Care Surg. 2018 Mar;84(3):532-536. doi: 10.1097/TA.0000000000001779. Review. No abstract available.

PMID:
29462114
13.

Clinical relevance of a p-value: Does TXA save lives after trauma or post-partum hemorrhage?

Dobson GP, Doma K, Letson HL.

J Trauma Acute Care Surg. 2017 Dec 28. doi: 10.1097/TA.0000000000001779. [Epub ahead of print] No abstract available.

PMID:
29283963
14.

The Adenosine Hypothesis Revisited: Modulation of Coupling between Myocardial Perfusion and Arterial Compliance.

Dobson GP, Arsyad A, Letson HL.

Front Physiol. 2017 Oct 20;8:824. doi: 10.3389/fphys.2017.00824. eCollection 2017.

15.

Tranexamic acid for post-partum haemorrhage in the WOMAN trial.

Letson HL, Dobson GP.

Lancet. 2017 Sep 30;390(10102):1581-1582. doi: 10.1016/S0140-6736(17)31947-5. Epub 2017 Sep 28. No abstract available.

PMID:
28980953
16.

Immune-inflammatory activation after a single laparotomy in a rat model: effect of adenosine, lidocaine and Mg2+ infusion to dampen the stress response.

Davenport L, Letson HL, Dobson GP.

Innate Immun. 2017 Jul;23(5):482-494. doi: 10.1177/1753425917718921.

PMID:
28691873
17.

Tranexamic acid leads to paradoxical coagulation changes during cardiac surgery: a pilot rotational thromboelastometry study.

Sharma R, Letson HL, Smith S, Dobson GP.

J Surg Res. 2017 Sep;217:100-112. doi: 10.1016/j.jss.2017.05.006. Epub 2017 May 8.

PMID:
28602219
18.

3% NaCl adenosine, lidocaine, Mg2+ (ALM) bolus and 4 hours "drip" infusion reduces noncompressible hemorrhage by 60% in a rat model.

Letson HL, Dobson GP.

J Trauma Acute Care Surg. 2017 Jun;82(6):1063-1072. doi: 10.1097/TA.0000000000001454.

PMID:
28520687
19.

Buprenorphine Analgesia Leads to Coagulopathy and Increased Plasma Fibrinogen in Healthy Rats: Implications For Small Animal Research.

Griffin MJ, Letson HL, Dobson GP.

Shock. 2017 Jul;48(1):78-84. doi: 10.1097/SHK.0000000000000821.

PMID:
27984521
20.
21.

Differential contributions of platelets and fibrinogen to early coagulopathy in a rat model of hemorrhagic shock.

Letson HL, Dobson GP.

Thromb Res. 2016 May;141:58-65. doi: 10.1016/j.thromres.2016.03.007. Epub 2016 Mar 7.

PMID:
26970714
22.

Adenosine, lidocaine, and Mg2+ (ALM): From cardiac surgery to combat casualty care--Teaching old drugs new tricks.

Dobson GP, Letson HL.

J Trauma Acute Care Surg. 2016 Jan;80(1):135-45. doi: 10.1097/TA.0000000000000881. Review.

PMID:
26683400
23.

Mechanisms of early trauma-induced coagulopathy: The clot thickens or not?

Dobson GP, Letson HL, Sharma R, Sheppard FR, Cap AP.

J Trauma Acute Care Surg. 2015 Aug;79(2):301-9. doi: 10.1097/TA.0000000000000729.

PMID:
26218701
24.

Correction of acute traumatic coagulopathy with small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ occurs within 5 minutes: a ROTEM analysis.

Letson HL, Dobson GP.

J Trauma Acute Care Surg. 2015 Apr;78(4):773-83. doi: 10.1097/TA.0000000000000587.

PMID:
25807406
25.

Adenosine, lidocaine and Mg2+ improves cardiac and pulmonary function, induces reversible hypotension and exerts anti-inflammatory effects in an endotoxemic porcine model.

Granfeldt A, Letson HL, Dobson GP, Shi W, Vinten-Johansen J, Tønnesen E.

Crit Care. 2014 Dec 11;18(6):682. doi: 10.1186/s13054-014-0682-y.

26.

Adenosine, lidocaine and Mg2+ (ALM) induces a reversible hypotensive state, reduces lung edema and prevents coagulopathy in the rat model of polymicrobial sepsis.

Griffin MJ, Letson HL, Dobson GP.

J Trauma Acute Care Surg. 2014 Sep;77(3):471-8. doi: 10.1097/TA.0000000000000361.

PMID:
25159253
27.

Small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ has multiple benefits during hypotensive and blood resuscitation in the pig following severe blood loss: rat to pig translation.

Granfeldt A, Letson HL, Hyldebrandt JA, Wang ER, Salcedo PA, Nielsen TK, Tønnesen E, Vinten-Johansen J, Dobson GP.

Crit Care Med. 2014 May;42(5):e329-44. doi: 10.1097/CCM.0000000000000225.

PMID:
24557427
28.

Optimization of the rodent model of polymicrobial sepsis.

Griffin M, Letson HL, Dobson GP.

Int Immunopharmacol. 2014 Apr;19(2):405. doi: 10.1016/j.intimp.2014.01.016. Epub 2014 Jan 29. No abstract available.

PMID:
24485942
29.

The Bellamy challenge: it's about time.

Dobson GP, Letson HL, Tadaki D.

J R Army Med Corps. 2014 Mar;160(1):9-15. doi: 10.1136/jramc-2013-000145. Epub 2013 Oct 18. Review.

PMID:
24142962
30.

Adenosine, lidocaine, and Mg2+ (ALM™) increases survival and corrects coagulopathy after eight-minute asphyxial cardiac arrest in the rat.

Djabir Y, Letson HL, Dobson GP.

Shock. 2013 Sep;40(3):222-32. doi: 10.1097/SHK.0b013e3182a03566.

PMID:
23846412
31.

Acute coagulopathy of trauma in the rat. Shock 39: 440-446, 2013.

Letson HL, Dobson GP.

Shock. 2013 Jul;40(1):74. doi: 10.1097/SHK.0b013e318296e18e. No abstract available.

PMID:
23770764
32.

Reversal of acute coagulopathy during hypotensive resuscitation using small-volume 7.5% NaCl adenocaine and Mg2+ in the rat model of severe hemorrhagic shock.

Letson HL, Pecheniuk NM, Mhango LP, Dobson GP.

Crit Care Med. 2012 Aug;40(8):2417-22. doi: 10.1097/CCM.0b013e31825334c3.

PMID:
22809911
33.
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