Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 85


Identification of Disease Risk DNA Variations is Shaping the Future of Precision Health.

Fakhouri WD, Letra A.

Genes (Basel). 2019 Jun 13;10(6). pii: E450. doi: 10.3390/genes10060450.


Potential role of TP63 in apical periodontitis development.

Souza LC, Crozeta BM, Guajardo L, Brasil da Costa FH, Sousa-Neto MD, Letra A, Silva RM.

Int Endod J. 2019 Apr 26. doi: 10.1111/iej.13133. [Epub ahead of print]


Association of IFT88 gene variants with nonsyndromic cleft lip with or without cleft palate.

Barba A, Urbina C, Maili L, Greives MR, Blackwell SJ, Mulliken JB, Chiquet B, Blanton SH, Hecht JT, Letra A.

Birth Defects Res. 2019 Apr 5. doi: 10.1002/bdr2.1504. [Epub ahead of print]


Investigating Potential Correlations between Endodontic Pathology and Cardiovascular Diseases Using Epidemiological and Genetic Approaches.

Messing M, Souza LC, Cavalla F, Kookal KK, Rizzo G, Walji M, Silva R, Letra A.

J Endod. 2019 Feb;45(2):104-110. doi: 10.1016/j.joen.2018.10.014. Epub 2019 Jan 17.


TBX21-1993T/C polymorphism association with Th1 and Th17 response at periapex and with periapical lesions development risk.

Colavite PM, Cavalla F, Garlet TP, Azevedo MCS, Melchiades JL, Campanelli AP, Letra A, Trombone APF, Silva RM, Garlet GP.

J Leukoc Biol. 2019 Mar;105(3):609-619. doi: 10.1002/JLB.6A0918-339R. Epub 2018 Dec 13.


Further evidence for the role of WNT10A, WNT10B and GREM2 as candidate genes for isolated tooth agenesis.

Magruder S, Carter E, Williams MA, English J, Akyalcin S, Letra A.

Orthod Craniofac Res. 2018 Nov;21(4):258-263. doi: 10.1111/ocr.12248. Epub 2018 Oct 4.


Are mTOR and Endoplasmic Reticulum Stress Pathway Genes Associated with Oral and Bone Diseases?

Bezamat M, Deeley K, Khaliq S, Letra A, Scariot R, Silva RM, Weber ML, Bussaneli DG, Trevilatto PC, Almarza AJ, Ouyang H, Vieira AR.

Caries Res. 2019;53(3):235-241. doi: 10.1159/000492675. Epub 2018 Sep 11.


Identification of likely pathogenic and known variants in TSPEAR, LAMB3, BCOR, and WNT10A in four Turkish families with tooth agenesis.

Du R, Dinckan N, Song X, Coban-Akdemir Z, Jhangiani SN, Guven Y, Aktoren O, Kayserili H, Petty LE, Muzny DM, Below JE, Boerwinkle E, Wu N, Gibbs RA, Posey JE, Lupski JR, Letra A, Uyguner ZO.

Hum Genet. 2018 Sep;137(9):689-703. doi: 10.1007/s00439-018-1907-y. Epub 2018 Jul 26.


BRCA1 and BRCA2 gene variants and nonsyndromic cleft lip/palate.

Rodriguez N, Maili L, Chiquet BT, Blanton SH, Hecht JT, Letra A.

Birth Defects Res. 2018 Jul 17;110(12):1043-1048. doi: 10.1002/bdr2.1346. Epub 2018 Jun 19.


DNA methylation profiles of immune response-related genes in apical periodontitis.

Wichnieski C, Maheshwari K, Souza LC, Nieves F, Tartari T, Garlet GP, Carneiro E, Letra A, Silva RM.

Int Endod J. 2019 Jan;52(1):5-12. doi: 10.1111/iej.12966. Epub 2018 Jul 3.


Knockdown of Crispld2 in zebrafish identifies a novel network for nonsyndromic cleft lip with or without cleft palate candidate genes.

Chiquet BT, Yuan Q, Swindell EC, Maili L, Plant R, Dyke J, Boyer R, Teichgraeber JF, Greives MR, Mulliken JB, Letra A, Blanton SH, Hecht JT.

Eur J Hum Genet. 2018 Oct;26(10):1441-1450. doi: 10.1038/s41431-018-0192-5. Epub 2018 Jun 13.


Effect of the combination of several irrigants on dentine surface properties, adsorption of chlorhexidine and adhesion of microorganisms to dentine.

Tartari T, Wichnieski C, Bachmann L, Jafelicci M Jr, Silva RM, Letra A, van der Hoeven R, Duarte MAH, Bramante CM.

Int Endod J. 2018 Dec;51(12):1420-1433. doi: 10.1111/iej.12960. Epub 2018 Jun 29.


The Changing Landscape in the Genetic Etiology of Human Tooth Agenesis.

Williams MA, Letra A.

Genes (Basel). 2018 May 16;9(5). pii: E255. doi: 10.3390/genes9050255. Review.


RANKL Triggers Treg-Mediated Immunoregulation in Inflammatory Osteolysis.

Francisconi CF, Vieira AE, Azevedo MCS, Tabanez AP, Fonseca AC, Trombone APF, Letra A, Silva RM, Sfeir CS, Little SR, Garlet GP.

J Dent Res. 2018 Jul;97(8):917-927. doi: 10.1177/0022034518759302. Epub 2018 Mar 2.


Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development.

Williams MA, Biguetti C, Romero-Bustillos M, Maheshwari K, Dinckan N, Cavalla F, Liu X, Silva R, Akyalcin S, Uyguner ZO, Vieira AR, Amendt BA, Fakhouri WD, Letra A.

Sci Rep. 2018 Feb 14;8(1):2979. doi: 10.1038/s41598-018-21368-z.


Association of WNT Pathway Genes With Nonsyndromic Cleft Lip With or Without Cleft Palate.

Vijayan V, Ummer R, Weber R, Silva R, Letra A.

Cleft Palate Craniofac J. 2018 Mar;55(3):335-341. doi: 10.1177/1055665617732782. Epub 2017 Dec 14.


A biallelic ANTXR1 variant expands the anthrax toxin receptor associated phenotype to tooth agenesis.

Dinckan N, Du R, Akdemir ZC, Bayram Y, Jhangiani SN, Doddapaneni H, Hu J, Muzny DM, Guven Y, Aktoren O, Kayserili H, Boerwinkle E, Gibbs RA, Posey JE, Lupski JR, Uyguner ZO, Letra A.

Am J Med Genet A. 2018 Apr;176(4):1015-1022. doi: 10.1002/ajmg.a.38625. Epub 2018 Feb 13.


PVR/CD155 Ala67Thr Mutation and Cleft Lip/Palate.

Vieira AR, Letra A, Silva RM, Granjeiro JM, Shimizu T, Poletta FA, Mereb JC, Castilla EE, Orioli IM.

J Craniofac Surg. 2018 Mar;29(2):347-352. doi: 10.1097/SCS.0000000000004159.


Role of WNT10A in failure of tooth development in humans and zebrafish.

Yuan Q, Zhao M, Tandon B, Maili L, Liu X, Zhang A, Baugh EH, Tran T, Silva RM, Hecht JT, Swindell EC, Wagner DS, Letra A.

Mol Genet Genomic Med. 2017 Nov;5(6):730-741. doi: 10.1002/mgg3.332. Epub 2017 Sep 14.


CCR5Δ32 (rs333) polymorphism is associated with decreased risk of chronic and aggressive periodontitis: A case-control analysis based in disease resistance and susceptibility phenotypes.

Cavalla F, Biguetti CC, Dionisio TJ, Azevedo MCS, Martins W Jr, Santos CF, Trombone APF, Silva RM, Letra A, Garlet GP.

Cytokine. 2018 Mar;103:142-149. doi: 10.1016/j.cyto.2017.09.022. Epub 2017 Sep 30.


Whole-Exome Sequencing Identifies Novel Variants for Tooth Agenesis.

Dinckan N, Du R, Petty LE, Coban-Akdemir Z, Jhangiani SN, Paine I, Baugh EH, Erdem AP, Kayserili H, Doddapaneni H, Hu J, Muzny DM, Boerwinkle E, Gibbs RA, Lupski JR, Uyguner ZO, Below JE, Letra A.

J Dent Res. 2018 Jan;97(1):49-59. doi: 10.1177/0022034517724149. Epub 2017 Aug 16.


Proteomic Profiling and Differential Messenger RNA Expression Correlate HSP27 and Serpin Family B Member 1 to Apical Periodontitis Outcomes.

Cavalla F, Biguetti C, Jain S, Johnson C, Letra A, Garlet GP, Silva RM.

J Endod. 2017 Sep;43(9):1486-1493. doi: 10.1016/j.joen.2017.03.014. Epub 2017 Jun 30.


Characterization of a Vascular Endothelial Growth Factor-loaded Bioresorbable Delivery System for Pulp Regeneration.

Yadlapati M, Biguetti C, Cavalla F, Nieves F, Bessey C, Bohluli P, Garlet GP, Letra A, Fakhouri WD, Silva RM.

J Endod. 2017 Jan;43(1):77-83. doi: 10.1016/j.joen.2016.09.022. Epub 2016 Dec 6.


Heat Shock 70 Protein Genes and Genetic Susceptibility to Apical Periodontitis.

Maheshwari K, Silva RM, Guajardo-Morales L, Garlet GP, Vieira AR, Letra A.

J Endod. 2016 Oct;42(10):1467-71. doi: 10.1016/j.joen.2016.07.010. Epub 2016 Aug 25.


MMP1-1607 polymorphism increases the risk for periapical lesion development through the upregulation MMP-1 expression in association with pro-inflammatory milieu elements.

Trombone AP, Cavalla F, Silveira EM, Andreo CB, Francisconi CF, Fonseca AC, Letra A, Silva RM, Garlet GP.

J Appl Oral Sci. 2016 Jul-Aug;24(4):366-75. doi: 10.1590/1678-775720160112.


Characterization of the Protective Role of Regulatory T Cells in Experimental Periapical Lesion Development and Their Chemoattraction Manipulation as a Therapeutic Tool.

Francisconi CF, Vieira AE, Biguetti CC, Glowacki AJ, Trombone AP, Letra A, Menezes Silva R, Sfeir CS, Little SR, Garlet GP.

J Endod. 2016 Jan;42(1):120-6. doi: 10.1016/j.joen.2015.09.022. Epub 2015 Nov 14.


DNA Methylation of MMP9 Is Associated with High Levels of MMP-9 Messenger RNA in Periapical Inflammatory Lesions.

Campos K, Gomes CC, Farias LC, Silva RM, Letra A, Gomez RS.

J Endod. 2016 Jan;42(1):127-30. doi: 10.1016/j.joen.2015.10.002. Epub 2015 Nov 6.


Regulatory variant in FZD6 gene contributes to nonsyndromic cleft lip and palate in an African-American family.

Cvjetkovic N, Maili L, Weymouth KS, Hashmi SS, Mulliken JB, Topczewski J, Letra A, Yuan Q, Blanton SH, Swindell EC, Hecht JT.

Mol Genet Genomic Med. 2015 Sep;3(5):440-51. doi: 10.1002/mgg3.155. Epub 2015 May 7.


Analysis of radiopacity, pH and cytotoxicity of a new bioceramic material.

Souza LC, Yadlapati M, Dorn SO, Silva R, Letra A.

J Appl Oral Sci. 2015 Jul-Aug;23(4):383-9. doi: 10.1590/1678-775720150065.


Evaluating the effects of different dental devices on implantable cardioverter defibrillators.

Maheshwari KR, Nikdel K, Guillaume G, Letra AM, Silva RM, Dorn SO.

J Endod. 2015 May;41(5):692-5. doi: 10.1016/j.joen.2014.12.011. Epub 2015 Feb 26.


Analysis of multiple cytokine polymorphisms in individuals with untreated deep carious lesions reveals IL1B (rs1143643) as a susceptibility factor for periapical lesion development.

Dill A, Letra A, Chaves de Souza L, Yadlapati M, Biguetti CC, Garlet GP, Vieira AR, Silva RM.

J Endod. 2015 Feb;41(2):197-200. doi: 10.1016/j.joen.2014.10.016. Epub 2014 Dec 2.


FOXP3 DNA methylation levels as a potential biomarker in the development of periapical lesions.

Campos K, Franscisconi CF, Okehie V, de Souza LC, Trombone AP, Letra A, Garlet GP, Gomez RS, Silva RM.

J Endod. 2015 Feb;41(2):212-8. doi: 10.1016/j.joen.2014.10.003. Epub 2014 Nov 11.


Mesenchymal stem cells as active prohealing and immunosuppressive agents in periapical environment: evidence from human and experimental periapical lesions.

Araujo-Pires AC, Biguetti CC, Repeke CE, Rodini Cde O, Campanelli AP, Trombone AP, Letra A, Silva RM, Garlet GP.

J Endod. 2014 Oct;40(10):1560-5. doi: 10.1016/j.joen.2014.02.012. Epub 2014 Apr 8.


Further evidence suggesting a role for variation in ARHGAP29 variants in nonsyndromic cleft lip/palate.

Letra A, Maili L, Mulliken JB, Buchanan E, Blanton SH, Hecht JT.

Birth Defects Res A Clin Mol Teratol. 2014 Sep;100(9):679-85. doi: 10.1002/bdra.23286. Epub 2014 Aug 27.


Simultaneous analysis of T helper subsets (Th1, Th2, Th9, Th17, Th22, Tfh, Tr1 and Tregs) markers expression in periapical lesions reveals multiple cytokine clusters accountable for lesions activity and inactivity status.

Araujo-Pires AC, Francisconi CF, Biguetti CC, Cavalla F, Aranha AM, Letra A, Trombone AP, Faveri M, Silva RM, Garlet GP.

J Appl Oral Sci. 2014 Jul-Aug;22(4):336-46.


Expression of heat shock proteins in periapical granulomas.

Goodman SC, Letra A, Dorn S, Araujo-Pires AC, Vieira AE, Chaves de Souza L, Yadlapati M, Garlet GP, Silva RM.

J Endod. 2014 Jun;40(6):830-6. doi: 10.1016/j.joen.2013.10.021. Epub 2013 Nov 25.


Functional Significance of MMP3 and TIMP2 Polymorphisms in Cleft Lip/Palate.

Letra A, Zhao M, Silva RM, Vieira AR, Hecht JT.

J Dent Res. 2014 Jul;93(7):651-6. doi: 10.1177/0022034514534444. Epub 2014 May 5.


Colorectal cancer and self-reported tooth agenesis.

Lindor NM, Win AK, Gallinger S, Daftary D, Thibodeau SN, Silva R, Letra A.

Hered Cancer Clin Pract. 2014 Mar 10;12(1):7. doi: 10.1186/1897-4287-12-7.


Association of WNT9B Gene Polymorphisms With Nonsyndromic Cleft Lip With or Without Cleft Palate in Brazilian Nuclear Families.

Fontoura C, Silva RM, Granjeiro JM, Letra A.

Cleft Palate Craniofac J. 2015 Jan;52(1):44-8. doi: 10.1597/13-146.


Deleterious effect of triple antibiotic paste on human periodontal ligament fibroblasts.

Yadlapati M, Souza LC, Dorn S, Garlet GP, Letra A, Silva RM.

Int Endod J. 2014 Aug;47(8):769-75. doi: 10.1111/iej.12216. Epub 2013 Dec 11.


MMP-7 and TIMP-1, new targets in predicting poor wound healing in apical periodontitis.

Letra A, Ghaneh G, Zhao M, Ray H Jr, Francisconi CF, Garlet GP, Silva RM.

J Endod. 2013 Sep;39(9):1141-6. doi: 10.1016/j.joen.2013.06.015.


Role of TRAV locus in low caries experience.

Briseño-Ruiz J, Shimizu T, Deeley K, Dizak PM, Ruff TD, Faraco IM Jr, Poletta FA, Brancher JA, Pecharki GD, Küchler EC, Tannure PN, Lips A, Vieira TC, Patir A, Koruyucu M, Mereb JC, Resick JM, Brandon CA, Letra A, Silva RM, Cooper ME, Seymen F, Costa MC, Granjeiro JM, Trevilatto PC, Orioli IM, Castilla EE, Marazita ML, Vieira AR.

Hum Genet. 2013 Sep;132(9):1015-25. doi: 10.1007/s00439-013-1313-4. Epub 2013 May 9.


Evidence supporting a protective role for th9 and th22 cytokines in human and experimental periapical lesions.

Aranha AM, Repeke CE, Garlet TP, Vieira AE, Campanelli AP, Trombone AP, Letra A, Silva RM, Garlet GP.

J Endod. 2013 Jan;39(1):83-7. doi: 10.1016/j.joen.2012.10.015. Epub 2012 Nov 10.


Further evidence of association of the ABCA4 gene with cleft lip/palate.

Fontoura C, Silva RM, Granjeiro JM, Letra A.

Eur J Oral Sci. 2012 Dec;120(6):553-7. doi: 10.1111/eos.12001. Epub 2012 Oct 15.


Interaction between IRF6 and TGFA genes contribute to the risk of nonsyndromic cleft lip/palate.

Letra A, Fakhouri W, Fonseca RF, Menezes R, Kempa I, Prasad JL, McHenry TG, Lidral AC, Moreno L, Murray JC, Daack-Hirsch S, Marazita ML, Castilla EE, Lace B, Orioli IM, Granjeiro JM, Schutte BC, Vieira AR.

PLoS One. 2012;7(9):e45441. doi: 10.1371/journal.pone.0045441. Epub 2012 Sep 20.


Association of MMP3 and TIMP2 promoter polymorphisms with nonsyndromic oral clefts.

Letra A, Silva RM, Motta LG, Blanton SH, Hecht JT, Granjeirol JM, Vieira AR.

Birth Defects Res A Clin Mol Teratol. 2012 Jul;94(7):540-8. doi: 10.1002/bdra.23026. Epub 2012 Jun 22.


Genetic analysis of the IL8 gene polymorphism (rs4073) in generalized aggressive periodontitis.

Andia DC, Letra A, Casarin RC, Casati MZ, Line SR, de Souza AP.

Arch Oral Biol. 2013 Feb;58(2):211-7. doi: 10.1016/j.archoralbio.2012.05.008. Epub 2012 Jun 20.


MMP3 and TIMP1 variants contribute to chronic periodontitis and may be implicated in disease progression.

Letra A, Silva RM, Rylands RJ, Silveira EM, de Souza AP, Wendell SK, Garlet GP, Vieira AR.

J Clin Periodontol. 2012 Aug;39(8):707-16. doi: 10.1111/j.1600-051X.2012.01902.x. Epub 2012 Jun 3.

Supplemental Content

Support Center