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Items: 1 to 50 of 156

1.

The tumor inflammation signature (TIS) is associated with anti-PD-1 treatment benefit in the CERTIM pan-cancer cohort.

Damotte D, Warren S, Arrondeau J, Boudou-Rouquette P, Mansuet-Lupo A, Biton J, Ouakrim H, Alifano M, Gervais C, Bellesoeur A, Kramkimel N, Tlemsani C, Burroni B, Duche A, Letourneur F, Si H, Halpin R, Creasy T, Herbst R, Ren X, Morel P, Cesano A, Goldwasser F, Leroy K.

J Transl Med. 2019 Nov 4;17(1):357. doi: 10.1186/s12967-019-2100-3.

2.

CD117hi expression identifies a human fetal Hematopoietic Stem Cell population with high proliferation and self-renewal potential.

Maillard L, Sanfilippo S, Domenech C, Kasmi N, Petit L, Jacques S, Delezoide AL, Guimiot F, Eladak S, Moison D, Nicolas N, Rouiller-Fabre V, Pozzi-Godin S, Mennesson B, Brival ML, Letourneur F, Jaffredo T, Chomienne C, Souyri M.

Haematologica. 2019 Jun 27. pii: haematol.2018.207811. doi: 10.3324/haematol.2018.207811. [Epub ahead of print]

3.

The NRF2 transcriptional target NQO1 has low mRNA levels in TP53-mutated endometrial carcinomas.

Beinse G, Just PA, Rance B, Izac B, Letourneur F, Saidu NEB, Chouzenoux S, Nicco C, Goldwasser F, Pasmant E, Batteux F, Borghese B, Alexandre J, Leroy K.

PLoS One. 2019 Mar 25;14(3):e0214416. doi: 10.1371/journal.pone.0214416. eCollection 2019.

4.

Tracking Rift Valley fever: From Mali to Europe and other countries, 2016.

Tong C, Javelle E, Grard G, Dia A, Lacrosse C, Fourié T, Gravier P, Watier-Grillot S, Lancelot R, Letourneur F, Comby F, Grau M, Cassou L, Meynard JB, Briolant S, Leparc-Goffart I, Pommier de Santi V.

Euro Surveill. 2019 Feb;24(8). doi: 10.2807/1560-7917.ES.2019.24.8.1800213. Erratum in: Euro Surveill. 2019 Feb;24(9):.

5.

PtpA, a secreted tyrosine phosphatase from Staphylococcus aureus, contributes to virulence and interacts with coronin-1A during infection.

Gannoun-Zaki L, Pätzold L, Huc-Brandt S, Baronian G, Elhawy MI, Gaupp R, Martin M, Blanc-Potard AB, Letourneur F, Bischoff M, Molle V.

J Biol Chem. 2018 Oct 5;293(40):15569-15580. doi: 10.1074/jbc.RA118.003555. Epub 2018 Aug 21.

6.

Humanized Mouse Model to Study Type 1 Diabetes.

Luce S, Guinoiseau S, Gadault A, Letourneur F, Blondeau B, Nitschke P, Pasmant E, Vidaud M, Lemonnier F, Boitard C.

Diabetes. 2018 Sep;67(9):1816-1829. doi: 10.2337/db18-0202. Epub 2018 Jul 2.

7.

Non-invasive prenatal diagnosis of paternally inherited disorders from maternal plasma: detection of NF1 and CFTR mutations using droplet digital PCR.

Gruber A, Pacault M, El Khattabi LA, Vaucouleur N, Orhant L, Bienvenu T, Girodon E, Vidaud D, Leturcq F, Costa C, Letourneur F, Anselem O, Tsatsaris V, Goffinet F, Viot G, Vidaud M, Nectoux J.

Clin Chem Lab Med. 2018 Apr 25;56(5):728-738. doi: 10.1515/cclm-2017-0689.

PMID:
29613853
8.

Detection and monitoring of circulating tumor DNA in adrenocortical carcinoma.

Garinet S, Nectoux J, Neou M, Pasmant E, Jouinot A, Sibony M, Orhant L, Pipoli da Fonseca J, Perlemoine K, Bricaire L, Groussin L, Soubrane O, Dousset B, Libe R, Letourneur F, Bertherat J, Assié G.

Endocr Relat Cancer. 2018 Mar;25(3):L13-L17. doi: 10.1530/ERC-17-0467. Epub 2017 Dec 6. No abstract available.

PMID:
29212777
9.

Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5.

Bärlocher K, Hutter CAJ, Swart AL, Steiner B, Welin A, Hohl M, Letourneur F, Seeger MA, Hilbi H.

Nat Commun. 2017 Nov 16;8(1):1543. doi: 10.1038/s41467-017-01512-5.

10.

AhR-deficiency as a cause of demyelinating disease and inflammation.

Juricek L, Carcaud J, Pelhaitre A, Riday TT, Chevallier A, Lanzini J, Auzeil N, Laprévote O, Dumont F, Jacques S, Letourneur F, Massaad C, Agulhon C, Barouki R, Beraneck M, Coumoul X.

Sci Rep. 2017 Aug 29;7(1):9794. doi: 10.1038/s41598-017-09621-3.

11.

Calling Chromosome Alterations, DNA Methylation Statuses, and Mutations in Tumors by Simple Targeted Next-Generation Sequencing: A Solution for Transferring Integrated Pangenomic Studies into Routine Practice?

Garinet S, Néou M, de La Villéon B, Faillot S, Sakat J, Da Fonseca JP, Jouinot A, Le Tourneau C, Kamal M, Luscap-Rondof W, Boeva V, Gaujoux S, Vidaud M, Pasmant E, Letourneur F, Bertherat J, Assié G.

J Mol Diagn. 2017 Sep;19(5):776-787. doi: 10.1016/j.jmoldx.2017.06.005.

PMID:
28826610
12.

Comprehensive Identification of Meningococcal Genes and Small Noncoding RNAs Required for Host Cell Colonization.

Capel E, Zomer AL, Nussbaumer T, Bole C, Izac B, Frapy E, Meyer J, Bouzinba-Ségard H, Bille E, Jamet A, Cavau A, Letourneur F, Bourdoulous S, Rattei T, Nassif X, Coureuil M.

MBio. 2016 Aug 2;7(4). pii: e01173-16. doi: 10.1128/mBio.01173-16.

13.

Correction for Six et al., Molecular Characterization of Nonhemolytic and Nonpigmented Group B Streptococci Responsible for Human Invasive Infections.

Six A, Firon A, Plainvert C, Caplain C, Bouaboud A, Touak G, Dmytruk N, Longo M, Letourneur F, Fouet A, Trieu-Cuot P, Poyart C.

J Clin Microbiol. 2016 Jul;54(7):1932. doi: 10.1128/JCM.00964-16. No abstract available.

14.

Aneuploidy: the impact of chromosome imbalance on nuclear organization and overall genome expression.

Hervé B, Coussement A, Gilbert T, Dumont F, Jacques S, Cuisset L, Chicard M, Hizem S, Bourdoncle P, Letourneur F, Dupont C, Vialard F, Choiset A, Dupont JM.

Clin Genet. 2016 Jul;90(1):35-48. doi: 10.1111/cge.12731. Epub 2016 Mar 23.

PMID:
27283765
15.

Dictyostelium EHD associates with Dynamin and participates in phagosome maturation.

Gueho A, Bosmani C, Gopaldass N, Molle V, Soldati T, Letourneur F.

J Cell Sci. 2016 Jun 15;129(12):2354-67. doi: 10.1242/jcs.182857. Epub 2016 May 11.

16.

Identification by FFPE RNA-Seq of a new recurrent inversion leading to RBM10-TFE3 fusion in renal cell carcinoma with subtle TFE3 break-apart FISH pattern.

Just PA, Letourneur F, Pouliquen C, Dome F, Audebourg A, Biquet P, Vidaud M, Terris B, Sibony M, Pasmant E.

Genes Chromosomes Cancer. 2016 Jun;55(6):541-8. doi: 10.1002/gcc.22356. Epub 2016 Apr 7.

PMID:
26998913
17.

Droplet digital PCR combined with minisequencing, a new approach to analyze fetal DNA from maternal blood: application to the non-invasive prenatal diagnosis of achondroplasia.

Orhant L, Anselem O, Fradin M, Becker PH, Beugnet C, Deburgrave N, Tafuri G, Letourneur F, Goffinet F, Allach El Khattabi L, Leturcq F, Bienvenu T, Tsatsaris V, Nectoux J.

Prenat Diagn. 2016 May;36(5):397-406. doi: 10.1002/pd.4790. Epub 2016 Apr 7.

18.

Endothelial cell dysfunction and cardiac hypertrophy in the STOX1 model of preeclampsia.

Ducat A, Doridot L, Calicchio R, Méhats C, Vilotte JL, Castille J, Barbaux S, Couderc B, Jacques S, Letourneur F, Buffat C, Le Grand F, Laissue P, Miralles F, Vaiman D.

Sci Rep. 2016 Jan 13;6:19196. doi: 10.1038/srep19196.

19.

Molecular Characterization of Nonhemolytic and Nonpigmented Group B Streptococci Responsible for Human Invasive Infections.

Six A, Firon A, Plainvert C, Caplain C, Bouaboud A, Touak G, Dmytruk N, Longo M, Letourneur F, Fouet A, Trieu-Cuot P, Poyart C.

J Clin Microbiol. 2016 Jan;54(1):75-82. doi: 10.1128/JCM.02177-15. Epub 2015 Oct 21. Erratum in: J Clin Microbiol. 2016 Jul;54(7):1932.

20.

Identification of intellectual disability genes showing circadian clock-dependent expression in the mouse hippocampus.

Renaud J, Dumont F, Khelfaoui M, Foisset SR, Letourneur F, Bienvenu T, Khwaja O, Dorseuil O, Billuart P.

Neuroscience. 2015 Nov 12;308:11-50. doi: 10.1016/j.neuroscience.2015.08.066. Epub 2015 Sep 2.

PMID:
26341910
21.

Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth.

Lévy J, Cacheux W, Bara MA, L'Hermitte A, Lepage P, Fraudeau M, Trentesaux C, Lemarchand J, Durand A, Crain AM, Marchiol C, Renault G, Dumont F, Letourneur F, Delacre M, Schmitt A, Terris B, Perret C, Chamaillard M, Couty JP, Romagnolo B.

Nat Cell Biol. 2015 Aug;17(8):1062-73. doi: 10.1038/ncb3206. Epub 2015 Jul 27.

PMID:
26214133
22.

Astrocyte Transcriptome from the Mecp2(308)-Truncated Mouse Model of Rett Syndrome.

Delépine C, Nectoux J, Letourneur F, Baud V, Chelly J, Billuart P, Bienvenu T.

Neuromolecular Med. 2015 Dec;17(4):353-63. doi: 10.1007/s12017-015-8363-9. Epub 2015 Jul 25.

PMID:
26208914
23.

Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism.

Ambolet-Camoit A, Ottolenghi C, Leblanc A, Kim MJ, Letourneur F, Jacques S, Cagnard N, Guguen-Guillouzo C, Barouki R, Aggerbeck M.

Biochimie. 2015 Sep;116:79-91. doi: 10.1016/j.biochi.2015.07.003. Epub 2015 Jul 6.

24.

ERAP1 Gene Expression Is Influenced by Nonsynonymous Polymorphisms Associated With Predisposition to Spondyloarthritis.

Costantino F, Talpin A, Evnouchidou I, Kadi A, Leboime A, Said-Nahal R, Bonilla N, Letourneur F, Leturcq T, Ka Z, van Endert P, Garchon HJ, Chiocchia G, Breban M.

Arthritis Rheumatol. 2015 Jun;67(6):1525-34. doi: 10.1002/art.39072.

25.

Transcriptomic analysis of human placenta in intrauterine growth restriction.

Madeleneau D, Buffat C, Mondon F, Grimault H, Rigourd V, Tsatsaris V, Letourneur F, Vaiman D, Barbaux S, Gascoin G.

Pediatr Res. 2015 Jun;77(6):799-807. doi: 10.1038/pr.2015.40. Epub 2015 Mar 3.

PMID:
25734244
26.

Identification of susceptibility genes for peritoneal, ovarian, and deep infiltrating endometriosis using a pooled sample-based genome-wide association study.

Borghese B, Tost J, de Surville M, Busato F, Letourneur F, Mondon F, Vaiman D, Chapron C.

Biomed Res Int. 2015;2015:461024. doi: 10.1155/2015/461024. Epub 2015 Feb 4.

27.

Synergy of chemotherapy and immunotherapy revealed by a genome-scale analysis of murine tuberculosis.

Rodrigues RF, Zárate-Bladés CR, Rios WM, Soares LS, Souza PR, Brandão IT, Masson AP, Arnoldi FG, Ramos SG, Letourneur F, Jacques S, Cagnard N, Chiocchia G, Silva CL.

J Antimicrob Chemother. 2015;70(6):1774-83. doi: 10.1093/jac/dkv023. Epub 2015 Feb 16.

PMID:
25687643
28.

Impaired alveolarization and intra-uterine growth restriction in rats: a postnatal genome-wide analysis.

Zana-Taieb E, Pham H, Franco-Montoya ML, Jacques S, Letourneur F, Baud O, Jarreau PH, Vaiman D.

J Pathol. 2015 Feb;235(3):420-30. doi: 10.1002/path.4470.

PMID:
25347958
29.

Defective lysosome maturation and Legionella pneumophila replication in Dictyostelium cells mutant for the Arf GAP ACAP-A.

Baïlo N, Cosson P, Charette SJ, Paquet VE, Doublet P, Letourneur F.

J Cell Sci. 2014 Nov 1;127(Pt 21):4702-13. doi: 10.1242/jcs.154559. Epub 2014 Sep 4.

30.

Monocyte-derived dendritic cells from HLA-B27+ axial spondyloarthritis (SpA) patients display altered functional capacity and deregulated gene expression.

Talpin A, Costantino F, Bonilla N, Leboime A, Letourneur F, Jacques S, Dumont F, Amraoui S, Dutertre CA, Garchon HJ, Breban M, Chiocchia G.

Arthritis Res Ther. 2014 Aug 21;16(4):417. doi: 10.1186/s13075-014-0417-0.

31.

A systems biology approach for defining the molecular framework of the hematopoietic stem cell niche.

Charbord P, Pouget C, Binder H, Dumont F, Stik G, Levy P, Allain F, Marchal C, Richter J, Uzan B, Pflumio F, Letourneur F, Wirth H, Dzierzak E, Traver D, Jaffredo T, Durand C.

Cell Stem Cell. 2014 Sep 4;15(3):376-391. doi: 10.1016/j.stem.2014.06.005. Epub 2014 Jul 17.

32.

Reverse interferon signature is characteristic of antigen-presenting cells in human and rat spondyloarthritis.

Fert I, Cagnard N, Glatigny S, Letourneur F, Jacques S, Smith JA, Colbert RA, Taurog JD, Chiocchia G, Araujo LM, Breban M.

Arthritis Rheumatol. 2014 Apr;66(4):841-51. doi: 10.1002/art.38318.

33.

ARMC5 mutations in macronodular adrenal hyperplasia with Cushing's syndrome.

Assié G, Libé R, Espiard S, Rizk-Rabin M, Guimier A, Luscap W, Barreau O, Lefèvre L, Sibony M, Guignat L, Rodriguez S, Perlemoine K, René-Corail F, Letourneur F, Trabulsi B, Poussier A, Chabbert-Buffet N, Borson-Chazot F, Groussin L, Bertagna X, Stratakis CA, Ragazzon B, Bertherat J.

N Engl J Med. 2013 Nov 28;369(22):2105-14. doi: 10.1056/NEJMoa1304603.

34.

MEPE-derived ASARM peptide inhibits odontogenic differentiation of dental pulp stem cells and impairs mineralization in tooth models of X-linked hypophosphatemia.

Salmon B, Bardet C, Khaddam M, Naji J, Coyac BR, Baroukh B, Letourneur F, Lesieur J, Decup F, Le Denmat D, Nicoletti A, Poliard A, Rowe PS, Huet E, Vital SO, Linglart A, McKee MD, Chaussain C.

PLoS One. 2013;8(2):e56749. doi: 10.1371/journal.pone.0056749. Epub 2013 Feb 22.

35.

Dictyostelium ACAP-A is an ArfGAP involved in cytokinesis, cell migration and actin cytoskeleton dynamics.

Dias M, Blanc C, Thazar-Poulot N, Ben Larbi S, Cosson P, Letourneur F.

J Cell Sci. 2013 Feb 1;126(Pt 3):756-66. doi: 10.1242/jcs.113951. Epub 2012 Dec 21.

36.

Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in mice.

Mondoulet L, Dioszeghy V, Puteaux E, Ligouis M, Dhelft V, Letourneur F, Dupont C, Benhamou PH.

Clin Transl Allergy. 2012 Nov 12;2(1):22. doi: 10.1186/2045-7022-2-22.

37.

A genome-wide approach reveals novel imprinted genes expressed in the human placenta.

Barbaux S, Gascoin-Lachambre G, Buffat C, Monnier P, Mondon F, Tonanny MB, Pinard A, Auer J, Bessières B, Barlier A, Jacques S, Simeoni U, Dandolo L, Letourneur F, Jammes H, Vaiman D.

Epigenetics. 2012 Sep;7(9):1079-90. Epub 2012 Aug 16.

38.

Focal polymicrogyria are associated with submicroscopic chromosomal rearrangements detected by CGH microarray analysis.

Quelin C, Saillour Y, Poirier K, Roubertie A, Boddaert N, Desguerre I, Letourneur F, Beldjord C, Chelly J, Bahi-Buisson N.

Eur J Med Genet. 2012 Oct;55(10):527-30. doi: 10.1016/j.ejmg.2012.06.004. Epub 2012 Jul 2.

PMID:
22766001
39.

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).

Durand A, Donahue B, Peignon G, Letourneur F, Cagnard N, Slomianny C, Perret C, Shroyer NF, Romagnolo B.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8965-70. doi: 10.1073/pnas.1201652109. Epub 2012 May 14.

40.

Foxp3-independent loss of regulatory CD4+ T-cell suppressive capacities induced by self-deprivation.

Delpoux A, Poitrasson-Rivière M, Le Campion A, Pommier A, Yakonowsky P, Jacques S, Letourneur F, Randriamampita C, Lucas B, Auffray C.

Eur J Immunol. 2012 May;42(5):1237-49. doi: 10.1002/eji.201142148.

41.

Angiotensin II facilitates breast cancer cell migration and metastasis.

Rodrigues-Ferreira S, Abdelkarim M, Dillenburg-Pilla P, Luissint AC, di-Tommaso A, Deshayes F, Pontes CL, Molina A, Cagnard N, Letourneur F, Morel M, Reis RI, Casarini DE, Terris B, Couraud PO, Costa-Neto CM, Di Benedetto M, Nahmias C.

PLoS One. 2012;7(4):e35667. doi: 10.1371/journal.pone.0035667. Epub 2012 Apr 20.

42.

Epicutaneous immunotherapy (EPIT) blocks the allergic esophago-gastro-enteropathy induced by sustained oral exposure to peanuts in sensitized mice.

Mondoulet L, Dioszeghy V, Larcher T, Ligouis M, Dhelft V, Puteaux E, Cherel Y, Letourneur F, Dupont C, Benhamou PH.

PLoS One. 2012;7(2):e31967. doi: 10.1371/journal.pone.0031967. Epub 2012 Feb 21.

43.

Association between the IL-1 family gene cluster and spondyloarthritis.

Monnet D, Kadi A, Izac B, Lebrun N, Letourneur F, Zinovieva E, Said-Nahal R, Chiocchia G, Breban M.

Ann Rheum Dis. 2012 Jun;71(6):885-90. doi: 10.1136/annrheumdis-2011-200439. Epub 2012 Feb 6.

PMID:
22312160
44.

Identification of molecular pathways involved in oxaliplatin-associated sinusoidal dilatation.

Agostini J, Benoist S, Seman M, Julié C, Imbeaud S, Letourneur F, Cagnard N, Rougier P, Brouquet A, Zucman-Rossi J, Laurent-Puig P.

J Hepatol. 2012 Apr;56(4):869-76. doi: 10.1016/j.jhep.2011.10.023. Epub 2011 Dec 24.

PMID:
22200551
45.

Analysis of transcriptomic and proteomic profiles demonstrates improved Madin-Darby canine kidney cell function in a renal microfluidic biochip.

Snouber LC, Letourneur F, Chafey P, Broussard C, Monge M, Legallais C, Leclerc E.

Biotechnol Prog. 2012 Mar-Apr;28(2):474-84. doi: 10.1002/btpr.743. Epub 2011 Nov 16.

PMID:
22095740
46.

Combined transcriptomic-(1)H NMR metabonomic study reveals that monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes.

Ellero-Simatos S, Claus SP, Benelli C, Forest C, Letourneur F, Cagnard N, Beaune PH, de Waziers I.

J Proteome Res. 2011 Dec 2;10(12):5493-502. doi: 10.1021/pr200765v. Epub 2011 Nov 9.

47.

Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip.

Prot JM, Briffaut AS, Letourneur F, Chafey P, Merlier F, Grandvalet Y, Legallais C, Leclerc E.

PLoS One. 2011;6(8):e21268. doi: 10.1371/journal.pone.0021268. Epub 2011 Aug 8.

48.

Systematic candidate gene investigations in the SPA2 locus (9q32) show an association between TNFSF8 and susceptibility to spondylarthritis.

Zinovieva E, Kadi A, Letourneur F, Cagnard N, Izac B, Vigier A, Said-Nahal R, Elewaut D, de Vlam K, Pimentel-Santos F, Chiocchia G, Breban M.

Arthritis Rheum. 2011 Jul;63(7):1853-9. doi: 10.1002/art.30377.

49.

The transforming growth factor-α and cyclin D1 genes are direct targets of β-catenin signaling in hepatocyte proliferation.

Torre C, Benhamouche S, Mitchell C, Godard C, Veber P, Letourneur F, Cagnard N, Jacques S, Finzi L, Perret C, Colnot S.

J Hepatol. 2011 Jul;55(1):86-95. doi: 10.1016/j.jhep.2010.10.021. Epub 2010 Nov 30.

PMID:
21145869
50.

Cell cloning-based transcriptome analysis in cyclin-dependent kinase-like 5 mutation patients with severe epileptic encephalopathy.

Nectoux J, Fichou Y, Cagnard N, Bahi-Buisson N, Nusbaum P, Letourneur F, Chelly J, Bienvenu T.

J Mol Med (Berl). 2011 Feb;89(2):193-202. doi: 10.1007/s00109-010-0699-x. Epub 2010 Nov 24.

PMID:
21107515

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