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Items: 7


Time dependent modulation of tumor radiosensitivity by a pan HDAC inhibitor: abexinostat.

Rivera S, Leteur C, Mégnin F, Law F, Martins I, Kloos I, Depil S, Modjtahedi N, Perfettini JL, Hennequin C, Deutsch E.

Oncotarget. 2017 Jan 25;8(34):56210-56227. doi: 10.18632/oncotarget.14813. eCollection 2017 Aug 22.


NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy.

Wu Q, Allouch A, Paoletti A, Leteur C, Mirjolet C, Martins I, Voisin L, Law F, Dakhli H, Mintet E, Thoreau M, Muradova Z, Gauthier M, Caron O, Milliat F, Ojcius DM, Rosselli F, Solary E, Modjtahedi N, Deutsch E, Perfettini JL.

Cell Death Differ. 2017 Sep;24(9):1632-1644. doi: 10.1038/cdd.2017.91. Epub 2017 Jun 2.


Preclinical assessment of JNJ-26854165 (Serdemetan), a novel tryptamine compound with radiosensitizing activity in vitro and in tumor xenografts.

Chargari C, Leteur C, Angevin E, Bashir T, Schoentjes B, Arts J, Janicot M, Bourhis J, Deutsch E.

Cancer Lett. 2011 Dec 22;312(2):209-18. doi: 10.1016/j.canlet.2011.08.011. Epub 2011 Aug 22.


[Pharmacological targeting of Mdm2: rationale and perspectives for radiosensitization].

Chargari C, Leteur C, Ferté C, Deberne M, Lahon B, Rivera C, Bourhis J, Deutsch E.

Cancer Radiother. 2011 Jul;15(4):316-22. doi: 10.1016/j.canrad.2011.02.003. Epub 2011 Jun 23. Review. French.


Dependence on phosphoinositide 3-kinase and RAS-RAF pathways drive the activity of RAF265, a novel RAF/VEGFR2 inhibitor, and RAD001 (Everolimus) in combination.

Mordant P, Loriot Y, Leteur C, Calderaro J, Bourhis J, Wislez M, Soria JC, Deutsch E.

Mol Cancer Ther. 2010 Feb;9(2):358-68. doi: 10.1158/1535-7163.MCT-09-1014. Epub 2010 Feb 2.


The aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe.

Tao Y, Leteur C, Calderaro J, Girdler F, Zhang P, Frascogna V, Varna M, Opolon P, Castedo M, Bourhis J, Kroemer G, Deutsch E.

Cell Cycle. 2009 Oct 1;8(19):3172-81. Epub 2009 Oct 4.


Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.

Tao Y, Leteur C, Yang C, Zhang P, Castedo M, Pierré A, Golsteyn RM, Bourhis J, Kroemer G, Deutsch E.

Cell Cycle. 2009 Apr 15;8(8):1196-205. Epub 2009 Apr 16.


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