Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 20

1.

TC-8831, a nicotinic acetylcholine receptor agonist, reduces L-DOPA-induced dyskinesia in the MPTP macaque.

Johnston TH, Huot P, Fox SH, Koprich JB, Szeliga KT, James JW, Graef JD, Letchworth SR, Jordan KG, Hill MP, Brotchie JM.

Neuropharmacology. 2013 Oct;73:337-47. doi: 10.1016/j.neuropharm.2013.06.005. Epub 2013 Jun 14.

PMID:
23770260
2.

Systemic administration of an alpha-7 nicotinic acetylcholine agonist reverses neuropathic pain in male Sprague Dawley rats.

Loram LC, Taylor FR, Strand KA, Maier SF, Speake JD, Jordan KG, James JW, Wene SP, Pritchard RC, Green H, Van Dyke K, Mazarov A, Letchworth SR, Watkins LR.

J Pain. 2012 Dec;13(12):1162-71. doi: 10.1016/j.jpain.2012.08.009.

3.

Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: correlation with desensitization of α4β2* receptors.

Zhang J, Xiao YD, Jordan KG, Hammond PS, Van Dyke KM, Mazurov AA, Speake JD, Lippiello PM, James JW, Letchworth SR, Bencherif M, Hauser TA.

Eur J Pharm Sci. 2012 Dec 18;47(5):813-23. doi: 10.1016/j.ejps.2012.09.014. Epub 2012 Oct 2.

PMID:
23036283
4.

Comparison of acetylcholine receptor interactions of the marine toxins, 13-desmethylspirolide C and gymnodimine.

Hauser TA, Hepler CD, Kombo DC, Grinevich VP, Kiser MN, Hooker DN, Zhang J, Mountfort D, Selwood A, Akireddy SR, Letchworth SR, Yohannes D.

Neuropharmacology. 2012 Jun;62(7):2239-50. doi: 10.1016/j.neuropharm.2012.01.009. Epub 2012 Jan 27.

PMID:
22306792
5.

Progress and challenges in the study of α6-containing nicotinic acetylcholine receptors.

Letchworth SR, Whiteaker P.

Biochem Pharmacol. 2011 Oct 15;82(8):862-72. doi: 10.1016/j.bcp.2011.06.022. Epub 2011 Jun 28. Review.

6.

Nicotinic receptors as targets for therapeutic discovery.

Lippiello P, Bencherif M, Hauser T, Jordan K, Letchworth S, Mazurov A.

Expert Opin Drug Discov. 2007 Sep;2(9):1185-203. doi: 10.1517/17460441.2.9.1185.

PMID:
23496128
7.

Ispronicline: a novel alpha4beta2 nicotinic acetylcholine receptor-selective agonist with cognition-enhancing and neuroprotective properties.

Lippiello P, Letchworth SR, Gatto GJ, Traina VM, Bencherif M.

J Mol Neurosci. 2006;30(1-2):19-20.

PMID:
17192610
8.

Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance.

Buccafusco JJ, Letchworth SR, Bencherif M, Lippiello PM.

Trends Pharmacol Sci. 2005 Jul;26(7):352-60. Review.

PMID:
15946748
9.

Heterologous expression of human {alpha}6{beta}4{beta}3{alpha}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {alpha}5 subunit.

Grinevich VP, Letchworth SR, Lindenberger KA, Menager J, Mary V, Sadieva KA, Buhlman LM, Bohme GA, Pradier L, Benavides J, Lukas RJ, Bencherif M.

J Pharmacol Exp Ther. 2005 Feb;312(2):619-26. Epub 2004 Sep 8.

PMID:
15356217
10.

TC-1734: an orally active neuronal nicotinic acetylcholine receptor modulator with antidepressant, neuroprotective and long-lasting cognitive effects.

Gatto GJ, Bohme GA, Caldwell WS, Letchworth SR, Traina VM, Obinu MC, Laville M, Reibaud M, Pradier L, Dunbar G, Bencherif M.

CNS Drug Rev. 2004 Summer;10(2):147-66. Review.

11.

Synthesis of a [2-pyridinyl-18F]-labelled fluoro derivative of (-)-cytisine as a candidate radioligand for brain nicotinic alpha4beta2 receptor imaging with PET.

Roger G, Lagnel B, Rouden J, Besret L, Valette H, Demphel S, Gopisetti J, Coulon C, Ottaviani M, Wrenn LA, Letchworth SR, Bohme GA, Benavides J, Lasne MC, Bottlaender M, Dollé F.

Bioorg Med Chem. 2003 Dec 1;11(24):5333-43.

PMID:
14642577
12.

Progression of changes in dopamine transporter binding site density as a result of cocaine self-administration in rhesus monkeys.

Letchworth SR, Nader MA, Smith HR, Friedman DP, Porrino LJ.

J Neurosci. 2001 Apr 15;21(8):2799-807.

13.

Functional and anatomical localization of mu opioid receptors in the striatum, amygdala, and extended amygdala of the nonhuman primate.

Daunais JB, Letchworth SR, Sim-Selley LJ, Smith HR, Childers SR, Porrino LJ.

J Comp Neurol. 2001 May 14;433(4):471-85.

PMID:
11304712
14.

Autoradiographic localization of (125)I[Tyr(14)]orphanin FQ/nociceptin and (125)I[Tyr(10)]orphanin FQ/nociceptin(1-11) binding sites in rat brain.

Letchworth SR, Mathis JP, Rossi GC, Bodnar RJ, Pasternak GW.

J Comp Neurol. 2000 Jul 24;423(2):319-29.

PMID:
10867661
15.

Characterization of a tropane radioligand, [(3)H]2beta-propanoyl-3beta-(4-tolyl) tropane ([(3)H]PTT), for dopamine transport sites in rat brain.

Letchworth SR, Smith HR, Porrino LJ, Bennett BA, Davies HM, Sexton T, Childers SR.

J Pharmacol Exp Ther. 2000 May;293(2):686-96.

PMID:
10773045
16.

Regulation of rat dopamine transporter mRNA and protein by chronic cocaine administration.

Letchworth SR, Sexton T, Childers SR, Vrana KE, Vaughan RA, Davies HM, Porrino LJ.

J Neurochem. 1999 Nov;73(5):1982-9.

17.

Identification of a high-affinity orphanin FQ/nociceptin(1-11) binding site in mouse brain.

Mathis JP, Goldberg IE, Letchworth SR, Ryan-Moro JP, Pasternak GW.

Synapse. 1999 Dec;34(3):181-6.

PMID:
10523755
18.

Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain.

Goldberg IE, Rossi GC, Letchworth SR, Mathis JP, Ryan-Moro J, Leventhal L, Su W, Emmel D, Bolan EA, Pasternak GW.

J Pharmacol Exp Ther. 1998 Aug;286(2):1007-13.

PMID:
9694962
19.

Long-acting blockade of biogenic amine transporters in rat brain by administration of the potent novel tropane 2beta-propanoyl-3beta-(2-Naphthyl)-tropane.

Daunais JB, Hart SL, Smith HR, Letchworth SR, Davies HM, Sexton T, Bennett BA, Childers SR, Porrino LJ.

J Pharmacol Exp Ther. 1998 Jun;285(3):1246-54. Erratum in: J Pharmacol Exp Ther 1998 Nov;287(2):814.

PMID:
9618429
20.

Effects of chronic cocaine administration on dopamine transporter mRNA and protein in the rat.

Letchworth SR, Daunais JB, Hedgecock AA, Porrino LJ.

Brain Res. 1997 Mar 7;750(1-2):214-22.

PMID:
9098547

Supplemental Content

Loading ...
Support Center