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Items: 1 to 50 of 298

1.

Concentrations of legacy and new contaminants are related to metabolite profiles in Hudson Bay polar bears.

Morris AD, Letcher RJ, Dyck M, Chandramouli B, Cosgrove J.

Environ Res. 2018 Oct 11;168:364-374. doi: 10.1016/j.envres.2018.10.001. [Epub ahead of print]

PMID:
30384230
2.

Down-Regulation of hspb9 and hspb11 Contributes to Wavy Notochord in Zebrafish Embryos Following Exposure to Polychlorinated Diphenylsulfides.

Zhang R, Wang X, Zhang X, Zhang J, Zhang X, Shi X, Crump D, Letcher RJ, Giesy JP, Liu C.

Environ Sci Technol. 2018 Oct 29. doi: 10.1021/acs.est.8b04487. [Epub ahead of print]

PMID:
30335980
3.

Chemical and biological transfer: Which one is responsible for the maternal transfer toxicity of tris(1,3-dichloro-2-propyl) phosphate in zebrafish?

Zhang Y, Su G, Li M, Li S, Wang Q, Zhu G, Letcher RJ, Liu C.

Environ Pollut. 2018 Dec;243(Pt B):1376-1382. doi: 10.1016/j.envpol.2018.09.114. Epub 2018 Sep 26.

PMID:
30273864
4.

Predicting global killer whale population collapse from PCB pollution.

Desforges JP, Hall A, McConnell B, Rosing-Asvid A, Barber JL, Brownlow A, De Guise S, Eulaers I, Jepson PD, Letcher RJ, Levin M, Ross PS, Samarra F, Víkingson G, Sonne C, Dietz R.

Science. 2018 Sep 28;361(6409):1373-1376. doi: 10.1126/science.aat1953.

PMID:
30262502
5.

Pollution threatens toothed whales.

Sonne C, Jepson PD, Desforges JP, Alstrup AKO, Olsen MT, Eulaers I, Hansen M, Letcher RJ, McKinney MA, Dietz R.

Science. 2018 Sep 21;361(6408):1208. doi: 10.1126/science.aav2403. No abstract available.

PMID:
30237348
6.

Sex-specific responses in neuroanatomy of hatchling American kestrels in response to embryonic exposure to the flame retardants bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate and 2-ethylhexyl-2,3,4,5-tetrabromobenzoate.

Guigueno MF, Karouna-Renier NK, Henry PFP, Peters LE, Palace VP, Letcher RJ, Fernie KJ.

Environ Toxicol Chem. 2018 Jul 23. doi: 10.1002/etc.4238. [Epub ahead of print]

PMID:
30035332
7.

Are ingested plastics a vector of PCB contamination in northern fulmars from coastal Newfoundland and Labrador?

Provencher JF, Avery-Gomm S, Liboiron M, Braune BM, Macaulay JB, Mallory ML, Letcher RJ.

Environ Res. 2018 Nov;167:184-190. doi: 10.1016/j.envres.2018.07.025. Epub 2018 Jul 17.

PMID:
30032001
8.

Unusually high Deca-BDE concentrations and new flame retardants in a Canadian Arctic top predator, the glaucous gull.

Verreault J, Letcher RJ, Gentes ML, Braune BM.

Sci Total Environ. 2018 Oct 15;639:977-987. doi: 10.1016/j.scitotenv.2018.05.222. Epub 2018 May 26.

PMID:
29929336
9.

Immunologic, reproductive, and carcinogenic risk assessment from POP exposure in East Greenland polar bears (Ursus maritimus) during 1983-2013.

Dietz R, Desforges JP, Gustavson K, Rigét FF, Born EW, Letcher RJ, Sonne C.

Environ Int. 2018 Sep;118:169-178. doi: 10.1016/j.envint.2018.05.020. Epub 2018 Jun 5.

PMID:
29883763
10.

Exposure to tris(1,3-dichloro-2-propyl) phosphate for Two generations decreases fecundity of zebrafish at environmentally relevant concentrations.

Zhang Y, Li M, Li S, Wang Q, Zhu G, Su G, Letcher RJ, Liu C.

Aquat Toxicol. 2018 Jul;200:178-187. doi: 10.1016/j.aquatox.2018.05.010. Epub 2018 May 15.

PMID:
29775925
11.

Isomer-Specific Hexabromocyclododecane (HBCDD) Levels in Top Predator Fish from Across Canada and 36-Year Temporal Trends in Lake Ontario.

Su G, McGoldrick DJ, Clark MG, Evans MS, Gledhill M, Garron C, Armelin A, Backus SM, Letcher RJ.

Environ Sci Technol. 2018 Jun 5;52(11):6197-6207. doi: 10.1021/acs.est.8b01052. Epub 2018 May 22.

PMID:
29737158
12.

Female hatchling American kestrels have a larger hippocampus than males: A link with sexual size dimorphism?

Guigueno MF, Karouna-Renier NK, Henry PFP, Head JA, Peters LE, Palace VP, Letcher RJ, Fernie KJ.

Behav Brain Res. 2018 Sep 3;349:98-101. doi: 10.1016/j.bbr.2018.04.037. Epub 2018 Apr 24.

PMID:
29702178
13.

Perfluoroalkyl Acids in European Starling Eggs Indicate Landfill and Urban Influences in Canadian Terrestrial Environments.

Gewurtz SB, Martin PA, Letcher RJ, Burgess NM, Champoux L, Elliott JE, Idrissi A.

Environ Sci Technol. 2018 May 15;52(10):5571-5580. doi: 10.1021/acs.est.7b06623. Epub 2018 Apr 25.

PMID:
29660979
14.

Liquid Crystal Monomers (LCMs): A New Generation of Persistent Bioaccumulative and Toxic (PBT) Compounds?

Li J, Su G, Letcher RJ, Xu W, Yang M, Zhang Y.

Environ Sci Technol. 2018 May 1;52(9):5005-5006. doi: 10.1021/acs.est.8b01636. Epub 2018 Apr 12. No abstract available.

PMID:
29648453
15.

Persistent organic pollutants and penile bone mineral density in East Greenland and Canadian polar bears (Ursus maritimus) during 1996-2015.

Daugaard-Petersen T, Langebæk R, Rigét FF, Dyck M, Letcher RJ, Hyldstrup L, Jensen JB, Dietz R, Sonne C.

Environ Int. 2018 May;114:212-218. doi: 10.1016/j.envint.2018.02.022. Epub 2018 Mar 6.

PMID:
29522985
16.

Polychlorinated Diphenylsulfides Activate Aryl Hydrocarbon Receptor 2 in Zebrafish Embryos: Potential Mechanism of Developmental Toxicity.

Zhang R, Wang X, Zhang X, Song C, Letcher RJ, Liu C.

Environ Sci Technol. 2018 Apr 3;52(7):4402-4412. doi: 10.1021/acs.est.8b00366. Epub 2018 Mar 15.

PMID:
29522672
17.

Covalent binding of the organophosphate insecticide profenofos to tyrosine on α- and β-tubulin proteins.

Chu S, Baker MR, Leong G, Letcher RJ, Li QX.

Chemosphere. 2018 May;199:154-159. doi: 10.1016/j.chemosphere.2018.02.003. Epub 2018 Feb 20.

PMID:
29433029
18.

A mixed-mode chromatographic separation method for the analysis of dialkyl phosphates.

Chu S, Letcher RJ.

J Chromatogr A. 2018 Feb 2;1535:63-71. doi: 10.1016/j.chroma.2017.12.069. Epub 2018 Jan 2.

PMID:
29306635
19.

Organophosphate esters in East Greenland polar bears and ringed seals: Adipose tissue concentrations and in vitro depletion and metabolite formation.

Strobel A, Willmore WG, Sonne C, Dietz R, Letcher RJ.

Chemosphere. 2018 Apr;196:240-250. doi: 10.1016/j.chemosphere.2017.12.181. Epub 2017 Dec 29.

PMID:
29306196
20.

Organophosphate triesters and selected metabolites enhance binding of thyroxine to human transthyretin in vitro.

Hill KL, Hamers T, Kamstra JH, Willmore WG, Letcher RJ.

Toxicol Lett. 2018 Mar 15;285:87-93. doi: 10.1016/j.toxlet.2017.12.030. Epub 2018 Jan 3.

PMID:
29306024
21.

Hepatic phase I and II biotransformation responses and contaminant exposure in long-finned pilot whales from the Northeastern Atlantic.

Hoydal KS, Jenssen BM, Letcher RJ, Dam M, Arukwe A.

Mar Environ Res. 2018 Mar;134:44-54. doi: 10.1016/j.marenvres.2017.12.010. Epub 2017 Dec 19.

PMID:
29290385
22.

Persistent organic pollutants, skull size and bone density of polar bears (Ursus maritimus) from East Greenland 1892-2015 and Svalbard 1964-2004.

Daugaard-Petersen T, Langebæk R, Rigét FF, Letcher RJ, Hyldstrup L, Jensen JB, Bechshoft T, Wiig Ø, Jenssen BM, Pertoldi C, Lorenzen ED, Dietz R, Sonne C.

Environ Res. 2018 Apr;162:74-80. doi: 10.1016/j.envres.2017.12.009. Epub 2017 Dec 26.

PMID:
29287182
23.

In Vitro and in Silico Competitive Binding of Brominated Polyphenyl Ether Contaminants with Human and Gull Thyroid Hormone Transport Proteins.

Hill KL, Mortensen ÅK, Teclechiel D, Willmore WG, Sylte I, Jenssen BM, Letcher RJ.

Environ Sci Technol. 2018 Feb 6;52(3):1533-1541. doi: 10.1021/acs.est.7b04617. Epub 2018 Jan 16.

PMID:
29283575
24.

Waste-water treatment plants are implicated as an important source of flame retardants in insectivorous tree swallows (Tachicyneta bicolor).

Fernie KJ, Letcher RJ.

Chemosphere. 2018 Mar;195:29-39. doi: 10.1016/j.chemosphere.2017.12.037. Epub 2017 Dec 7.

PMID:
29248750
25.

A veterinary perspective on One Health in the Arctic.

Sonne C, Letcher RJ, Jenssen BM, Desforges JP, Eulaers I, Andersen-Ranberg E, Gustavson K, Styrishave B, Dietz R.

Acta Vet Scand. 2017 Dec 16;59(1):84. doi: 10.1186/s13028-017-0353-5. Review.

26.

Photolysis of highly brominated flame retardants leads to time-dependent dioxin-responsive mRNA expression in chicken embryonic hepatocytes.

Su G, Letcher RJ, Farmahin R, Crump D.

Chemosphere. 2018 Mar;194:352-359. doi: 10.1016/j.chemosphere.2017.11.153. Epub 2017 Nov 30.

PMID:
29220751
27.

The distribution and trends of persistent organic pollutants and mercury in marine mammals from Canada's Eastern Arctic.

Brown TM, Macdonald RW, Muir DCG, Letcher RJ.

Sci Total Environ. 2018 Mar 15;618:500-517. doi: 10.1016/j.scitotenv.2017.11.052. Epub 2017 Nov 13. Review.

PMID:
29145101
28.

Optimization of an in vitro assay methodology for competitive binding of thyroidogenic xenobiotics with thyroxine on human transthyretin and albumin.

Hill KL, Hamers T, Kamstra JH, Willmore WG, Letcher RJ.

MethodsX. 2017 Oct 20;4:404-412. doi: 10.1016/j.mex.2017.10.004. eCollection 2017.

29.

Whole-Life-Stage Characterization in the Basic Biology of Daphnia magna and Effects of TDCIPP on Growth, Reproduction, Survival, and Transcription of Genes.

Li H, Yuan S, Su G, Li M, Wang Q, Zhu G, Letcher RJ, Li Y, Han Z, Liu C.

Environ Sci Technol. 2017 Dec 5;51(23):13967-13975. doi: 10.1021/acs.est.7b04569. Epub 2017 Nov 17.

PMID:
29115819
30.

Steroid hormones and persistent organic pollutants in plasma from North-eastern Atlantic pilot whales.

Hoydal KS, Styrishave B, Ciesielski TM, Letcher RJ, Dam M, Jenssen BM.

Environ Res. 2017 Nov;159:613-621. doi: 10.1016/j.envres.2017.09.003. Epub 2017 Sep 14.

PMID:
28918287
31.

Effects of Polar Bear and Killer Whale Derived Contaminant Cocktails on Marine Mammal Immunity.

Desforges JP, Levin M, Jasperse L, De Guise S, Eulaers I, Letcher RJ, Acquarone M, Nordøy E, Folkow LP, Hammer Jensen T, Grøndahl C, Bertelsen MF, St Leger J, Almunia J, Sonne C, Dietz R.

Environ Sci Technol. 2017 Oct 3;51(19):11431-11439. doi: 10.1021/acs.est.7b03532. Epub 2017 Sep 25.

PMID:
28876915
32.

Legacy and new halogenated persistent organic pollutants in polar bears from a contamination hotspot in the Arctic, Hudson Bay Canada.

Letcher RJ, Morris AD, Dyck M, Sverko E, Reiner EJ, Blair DAD, Chu SG, Shen L.

Sci Total Environ. 2018 Jan 1;610-611:121-136. doi: 10.1016/j.scitotenv.2017.08.035. Epub 2017 Aug 10.

PMID:
28803190
33.

Establishment of a three-step method to evaluate effects of chemicals on development of zebrafish embryo/larvae.

Li G, Ye H, Su G, Han Z, Xie C, Zhou B, Letcher RJ, Giesy JP, Yu H, Liu C.

Chemosphere. 2017 Nov;186:209-217. doi: 10.1016/j.chemosphere.2017.07.163. Epub 2017 Aug 2.

PMID:
28780448
34.

Volatile Methylsiloxanes and Organophosphate Esters in the Eggs of European Starlings (Sturnus vulgaris) and Congeneric Gull Species from Locations across Canada.

Lu Z, Martin PA, Burgess NM, Champoux L, Elliott JE, Baressi E, De Silva AO, de Solla SR, Letcher RJ.

Environ Sci Technol. 2017 Sep 5;51(17):9836-9845. doi: 10.1021/acs.est.7b03192. Epub 2017 Aug 23.

PMID:
28771368
35.

Side-chain fluorinated polymer surfactants in aquatic sediment and biosolid-augmented agricultural soil from the Great Lakes basin of North America.

Chu S, Letcher RJ.

Sci Total Environ. 2017 Dec 31;607-608:262-270. doi: 10.1016/j.scitotenv.2017.06.252. Epub 2017 Jul 27.

PMID:
28692896
36.

Halogenated Flame Retardants in Predator and Prey Fish From the Laurentian Great Lakes: Age-Dependent Accumulation and Trophic Transfer.

Su G, Letcher RJ, McGoldrick DJ, Backus SM.

Environ Sci Technol. 2017 Aug 1;51(15):8432-8441. doi: 10.1021/acs.est.7b02338. Epub 2017 Jul 11.

PMID:
28636346
37.

Time-dependent inhibitory effects of Tris(1, 3-dichloro-2-propyl) phosphate on growth and transcription of genes involved in the GH/IGF axis, but not the HPT axis, in female zebrafish.

Zhu Y, Su G, Yang D, Zhang Y, Yu L, Li Y, Giesy JP, Letcher RJ, Liu C.

Environ Pollut. 2017 Oct;229:470-478. doi: 10.1016/j.envpol.2017.06.024. Epub 2017 Jun 15.

PMID:
28624628
38.

Spatiotemporal patterns and relationships among the diet, biochemistry, and exposure to flame retardants in an apex avian predator, the peregrine falcon.

Fernie KJ, Chabot D, Champoux L, Brimble S, Alaee M, Marteinson S, Chen D, Palace V, Bird DM, Letcher RJ.

Environ Res. 2017 Oct;158:43-53. doi: 10.1016/j.envres.2017.05.035. Epub 2017 Jul 3.

PMID:
28599194
39.

Exploring adduct formation between human serum albumin and eleven organophosphate ester flame retardants and plasticizers using MALDI-TOF/TOF and LC-Q/TOF.

Chu S, Baker MR, Leong G, Letcher RJ, Gee SJ, Hammock BD, Li QX.

Chemosphere. 2017 Aug;180:169-177. doi: 10.1016/j.chemosphere.2017.03.124. Epub 2017 Mar 31.

40.

A rapid analytical method to quantify complex organohalogen contaminant mixtures in large samples of high lipid mammalian tissues.

Desforges JP, Eulaers I, Periard L, Sonne C, Dietz R, Letcher RJ.

Chemosphere. 2017 Jun;176:243-248. doi: 10.1016/j.chemosphere.2017.02.098. Epub 2017 Feb 24.

PMID:
28273531
41.

Effects of food-borne exposure of juvenile rainbow trout (Oncorhynchus mykiss) to emerging brominated flame retardants 1,2-bis(2,4,6-tribromophenoxy)ethane and 2-ethylhexyl-2,3,4,5-tetrabromobenzoate.

Giraudo M, Douville M, Letcher RJ, Houde M.

Aquat Toxicol. 2017 May;186:40-49. doi: 10.1016/j.aquatox.2017.02.023. Epub 2017 Feb 22.

PMID:
28249227
42.

Disruption of thyroxine and sex hormones by 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane (DBE-DBCH) in American kestrels (Falco sparverius) and associations with reproductive and behavioral changes.

Marteinson SC, Palace V, Letcher RJ, Fernie KJ.

Environ Res. 2017 Apr;154:389-397. doi: 10.1016/j.envres.2017.01.005. Epub 2017 Feb 9.

PMID:
28189029
43.

Contaminants of emerging concern in Caspian tern compared to herring gull eggs from Michigan colonies in the Great Lakes of North America.

Su G, Letcher RJ, Moore JN, Williams LL, Grasman KA.

Environ Pollut. 2017 Mar;222:154-164. doi: 10.1016/j.envpol.2016.12.061. Epub 2017 Jan 12.

PMID:
28089466
44.

Per- and polyfluoroalkyl substances (PFASs) - New endocrine disruptors in polar bears (Ursus maritimus)?

Pedersen KE, Letcher RJ, Sonne C, Dietz R, Styrishave B.

Environ Int. 2016 Nov;96:180-189. doi: 10.1016/j.envint.2016.07.015. Epub 2016 Sep 28.

PMID:
27692342
45.

Transfer of hexabromocyclododecane flame retardant isomers from captive American kestrel eggs to feathers and their association with thyroid hormones and growth.

Marteinson SC, Eulaers I, Jaspers VLB, Covaci A, Eens M, Letcher RJ, Fernie KJ.

Environ Pollut. 2017 Jan;220(Pt A):441-451. doi: 10.1016/j.envpol.2016.09.086. Epub 2016 Oct 1.

PMID:
27707600
46.

Parental transfer of tris(1,3-dichloro-2-propyl) phosphate and transgenerational inhibition of growth of zebrafish exposed to environmentally relevant concentrations.

Yu L, Jia Y, Su G, Sun Y, Letcher RJ, Giesy JP, Yu H, Han Z, Liu C.

Environ Pollut. 2017 Jan;220(Pt A):196-203. doi: 10.1016/j.envpol.2016.09.039. Epub 2016 Sep 16.

PMID:
27646168
47.

Raising the standard of systematic reviews published in Environment International.

Whaley P, Letcher RJ, Covaci A, Alcock R.

Environ Int. 2016 Dec;97:274-276. doi: 10.1016/j.envint.2016.08.007. Epub 2016 Aug 24. No abstract available.

PMID:
27567414
48.

Multigenerational effects of tris(1,3-dichloro-2-propyl) phosphate on the free-living ciliate protozoa Tetrahymena thermophila exposed to environmentally relevant concentrations and after subsequent recovery.

Li J, Ma X, Su G, Giesy JP, Xiao Y, Zhou B, Letcher RJ, Liu C.

Environ Pollut. 2016 Nov;218:50-58. doi: 10.1016/j.envpol.2016.08.034. Epub 2016 Aug 20.

PMID:
27552037
49.

Environmentally relevant organophosphate triesters in herring gulls: In vitro biotransformation and kinetics and diester metabolite formation using a hepatic microsomal assay.

Greaves AK, Su G, Letcher RJ.

Toxicol Appl Pharmacol. 2016 Oct 1;308:59-65. doi: 10.1016/j.taap.2016.08.007. Epub 2016 Aug 11.

PMID:
27523639
50.

A Review of Organophosphate Esters in the Environment from Biological Effects to Distribution and Fate.

Greaves AK, Letcher RJ.

Bull Environ Contam Toxicol. 2017 Jan;98(1):2-7. doi: 10.1007/s00128-016-1898-0. Epub 2016 Aug 10. Review.

PMID:
27510993

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