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Items: 11

1.

PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.

Ariës IM, Bodaar K, Karim SA, Chonghaile TN, Hinze L, Burns MA, Pfirrmann M, Degar J, Landrigan JT, Balbach S, Peirs S, Menten B, Isenhart R, Stevenson KE, Neuberg DS, Devidas M, Loh ML, Hunger SP, Teachey DT, Rabin KR, Winter SS, Dunsmore KP, Wood BL, Silverman LB, Sallan SE, Van Vlierberghe P, Orkin SH, Knoechel B, Letai AG, Gutierrez A.

J Exp Med. 2018 Nov 7. pii: jem.20180570. doi: 10.1084/jem.20180570. [Epub ahead of print]

PMID:
30404791
2.

Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways.

Saito Y, Mochizuki Y, Ogahara I, Watanabe T, Hogdal L, Takagi S, Sato K, Kaneko A, Kajita H, Uchida N, Fukami T, Shultz LD, Taniguchi S, Ohara O, Letai AG, Ishikawa F.

Sci Transl Med. 2017 Oct 25;9(413). pii: eaao1214. doi: 10.1126/scitranslmed.aao1214.

PMID:
29070697
3.

Cristae remodeling causes acidification detected by integrated graphene sensor during mitochondrial outer membrane permeabilization.

Pham TD, Pham PQ, Li J, Letai AG, Wallace DC, Burke PJ.

Sci Rep. 2016 Oct 27;6:35907. doi: 10.1038/srep35907.

4.

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.

Pan R, Hogdal LJ, Benito JM, Bucci D, Han L, Borthakur G, Cortes J, DeAngelo DJ, Debose L, Mu H, Döhner H, Gaidzik VI, Galinsky I, Golfman LS, Haferlach T, Harutyunyan KG, Hu J, Leverson JD, Marcucci G, Müschen M, Newman R, Park E, Ruvolo PP, Ruvolo V, Ryan J, Schindela S, Zweidler-McKay P, Stone RM, Kantarjian H, Andreeff M, Konopleva M, Letai AG.

Cancer Discov. 2014 Mar;4(3):362-75. doi: 10.1158/2159-8290.CD-13-0609. Epub 2013 Dec 17.

5.

Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis.

Murphy ÁC, Weyhenmeyer B, Noonan J, Kilbride SM, Schimansky S, Loh KP, Kögel D, Letai AG, Prehn JH, Murphy BM.

Apoptosis. 2014 Apr;19(4):629-42. doi: 10.1007/s10495-013-0935-2.

6.

The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance.

Barbone D, Ryan JA, Kolhatkar N, Chacko AD, Jablons DM, Sugarbaker DJ, Bueno R, Letai AG, Coussens LM, Fennell DA, Broaddus VC.

Cell Death Dis. 2011 Jun 23;2:e174. doi: 10.1038/cddis.2011.58.

7.

Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression.

Dutta-Simmons J, Zhang Y, Gorgun G, Gatt M, Mani M, Hideshima T, Takada K, Carlson NE, Carrasco DE, Tai YT, Raje N, Letai AG, Anderson KC, Carrasco DR.

Blood. 2009 Sep 24;114(13):2699-708. doi: 10.1182/blood-2008-12-194290. Epub 2009 Aug 3.

8.

Diagnosing and exploiting cancer's addiction to blocks in apoptosis.

Letai AG.

Nat Rev Cancer. 2008 Feb;8(2):121-32. doi: 10.1038/nrc2297. Review.

PMID:
18202696
9.

Smallpox and smallpox vaccination.

Letai AG.

N Engl J Med. 2003 May 8;348(19):1920-5; author reply 1920-5. No abstract available.

10.

Pancreas-graft immunogenicity and pretreatment with anti-class II monoclonal antibodies.

Lloyd DM, Cotler SJ, Letai AG, Stuart FP, Thistlethwaite JR Jr.

Diabetes. 1989 Jan;38 Suppl 1:104-8.

PMID:
2642828
11.

Specificity in formation of triple-stranded nucleic acid helical complexes: studies with agarose-linked polyribonucleotide affinity columns.

Letai AG, Palladino MA, Fromm E, Rizzo V, Fresco JR.

Biochemistry. 1988 Dec 27;27(26):9108-12.

PMID:
3242616

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